Published in J Cell Biol on May 25, 2009
Regulators of the cytoplasmic dynein motor. Nat Rev Mol Cell Biol (2009) 4.05
Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine. J Cell Biol (2010) 3.50
Sensing centromere tension: Aurora B and the regulation of kinetochore function. Trends Cell Biol (2010) 2.88
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Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells. Genes Dev (2010) 1.66
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Mutual regulation between the spindle checkpoint and APC/C. Semin Cell Dev Biol (2011) 1.29
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Spindle assembly checkpoint proteins are positioned close to core microtubule attachment sites at kinetochores. J Cell Biol (2013) 1.11
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Aurora B controls kinetochore-microtubule attachments by inhibiting Ska complex-KMN network interaction. J Cell Biol (2012) 1.09
Bub3p facilitates spindle checkpoint silencing in fission yeast. Mol Biol Cell (2009) 1.07
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Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint. Chromosoma (2012) 1.05
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Finding the middle ground: how kinetochores power chromosome congression. Cell Mol Life Sci (2010) 1.04
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MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progression. J Cell Biol (2013) 1.02
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Overcoming inhibition in the spindle checkpoint. Genes Dev (2009) 0.99
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On the regulation, function, and localization of the DNA-dependent ATPase PICH. Chromosoma (2012) 0.96
LIS1 controls mitosis and mitotic spindle organization via the LIS1-NDEL1-dynein complex. Hum Mol Genet (2013) 0.95
The current view for the silencing of the spindle assembly checkpoint. Cell Cycle (2014) 0.95
Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit. EMBO J (2013) 0.93
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A novel role of farnesylation in targeting a mitotic checkpoint protein, human Spindly, to kinetochores. J Cell Biol (2015) 0.91
Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors. Mol Biol Cell (2015) 0.86
Polo-like kinase1 is required for recruitment of dynein to kinetochores during mitosis. J Biol Chem (2011) 0.85
Function and regulation of dynein in mitotic chromosome segregation. Chromosoma (2014) 0.84
Molecular mechanism of dynein recruitment to kinetochores by the Rod-Zw10-Zwilch complex and Spindly. J Cell Biol (2017) 0.83
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Structure of the RZZ complex and molecular basis of its interaction with Spindly. J Cell Biol (2017) 0.82
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RanGTP aids anaphase entry through Ubr5-mediated protein turnover. J Cell Biol (2015) 0.78
Control of the spindle checkpoint by lateral kinetochore attachment and limited Mad1 recruitment. Mol Biol Cell (2015) 0.76
A maternal effect rough deal mutation suggests that multiple pathways regulate Drosophila RZZ kinetochore recruitment. J Cell Sci (2015) 0.76
Lipids beyond membranes; farnesylation targets Spindly to kinetochores. Cell Cycle (2015) 0.75
Phospho-regulation pathways during egg activation in Drosophila melanogaster. Genetics (2013) 0.75
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The human cytoplasmic dynein interactome reveals novel activators of motility. Elife (2017) 0.75
Palladin is a novel microtubule-associated protein responsible for spindle orientation. Sci Rep (2017) 0.75
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The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint. J Cell Biol (2003) 8.32
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A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function. Nat Cell Biol (2000) 5.29
Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation. J Cell Biol (2001) 5.03
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The structure of the cold-stable kinetochore fiber in metaphase PtK1 cells. Chromosoma (1981) 4.11
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Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1. Dev Cell (2007) 3.06
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Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1- and myosin X-dependent manner. EMBO J (2007) 2.73
Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division. Cell (2008) 2.68
Dynein/dynactin regulate metaphase spindle length by targeting depolymerizing activities to spindle poles. J Cell Biol (2004) 2.46
Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores. Nat Cell Biol (2000) 2.45
PtdIns(3,4,5)P3 regulates spindle orientation in adherent cells. Dev Cell (2007) 2.45
ZW10 links mitotic checkpoint signaling to the structural kinetochore. J Cell Biol (2005) 2.36
Proteome analysis of the human mitotic spindle. Mol Cell Proteomics (2004) 2.31
Mechanisms for focusing mitotic spindle poles by minus end-directed motor proteins. J Cell Biol (2005) 2.21
Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore. J Cell Biol (2007) 2.18
Kinetochore dynein is required for chromosome motion and congression independent of the spindle checkpoint. Curr Biol (2007) 2.18
Kinetochore dynein: its dynamics and role in the transport of the Rough deal checkpoint protein. Nat Cell Biol (2001) 2.17
Recruitment of Mad2 to the kinetochore requires the Rod/Zw10 complex. Curr Biol (2005) 2.10
Rod-Zw10-Zwilch: a key player in the spindle checkpoint. Trends Cell Biol (2005) 2.06
The rate of poleward chromosome motion is attenuated in Drosophila zw10 and rod mutants. Nat Cell Biol (2000) 2.03
Cenp-F links kinetochores to Ndel1/Nde1/Lis1/dynein microtubule motor complexes. Curr Biol (2007) 2.03
Cooperative mechanisms of mitotic spindle formation. J Cell Sci (2007) 2.02
Rough deal and Zw10 are required for the metaphase checkpoint in Drosophila. Nat Cell Biol (2000) 1.95
Centromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENP. Mol Biol Cell (2006) 1.94
NudE and NudEL are required for mitotic progression and are involved in dynein recruitment to kinetochores. J Cell Biol (2007) 1.85
Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi. EMBO J (2004) 1.82
Stable kinetochore-microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3. EMBO J (2009) 1.76
A new mechanism controlling kinetochore-microtubule interactions revealed by comparison of two dynein-targeting components: SPDL-1 and the Rod/Zwilch/Zw10 complex. Genes Dev (2008) 1.73
Gene silencing of CENP-E by small interfering RNA in HeLa cells leads to missegregation of chromosomes after a mitotic delay. Mol Biol Cell (2004) 1.73
Dynein is a transient kinetochore component whose binding is regulated by microtubule attachment, not tension. J Cell Biol (2000) 1.71
Phosphorylation regulates targeting of cytoplasmic dynein to kinetochores during mitosis. J Cell Biol (2008) 1.64
Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity. J Cell Biol (2007) 1.59
Nudel functions in membrane traffic mainly through association with Lis1 and cytoplasmic dynein. J Cell Biol (2004) 1.47
In vivo dynamics of the rough deal checkpoint protein during Drosophila mitosis. Curr Biol (2004) 1.42
Direct role of dynein motor in stable kinetochore-microtubule attachment, orientation, and alignment. J Cell Biol (2008) 1.41
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SPDL-1 functions as a kinetochore receptor for MDF-1 in Caenorhabditis elegans. J Cell Biol (2008) 1.10
Dynein light intermediate chain: an essential subunit that contributes to spindle checkpoint inactivation. Mol Biol Cell (2008) 1.09
Kinetochore dynein generates a poleward pulling force to facilitate congression and full chromosome alignment. Cell Res (2007) 0.97
Spindly attachments. Genes Dev (2008) 0.81
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature (2010) 9.95
Proteomic characterization of the human centrosome by protein correlation profiling. Nature (2003) 8.74
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci Signal (2010) 8.61
Polo-like kinases and the orchestration of cell division. Nat Rev Mol Cell Biol (2004) 7.22
The Polo kinase Plk4 functions in centriole duplication. Nat Cell Biol (2005) 5.84
Plk4-induced centriole biogenesis in human cells. Dev Cell (2007) 5.68
The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4. Nat Genet (2006) 5.36
Aurora B-mediated abscission checkpoint protects against tetraploidization. Cell (2009) 5.26
Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2. Science (2002) 4.94
Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells. EMBO J (2002) 4.54
Active cyclin B1-Cdk1 first appears on centrosomes in prophase. Nat Cell Biol (2003) 4.31
Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis. Mol Biol Cell (2003) 4.28
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Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together. Cell (2007) 3.98
Cep164, a novel centriole appendage protein required for primary cilium formation. J Cell Biol (2007) 3.88
PICH, a centromere-associated SNF2 family ATPase, is regulated by Plk1 and required for the spindle checkpoint. Cell (2007) 3.80
Human TPX2 is required for targeting Aurora-A kinase to the spindle. J Cell Biol (2002) 3.69
The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase. Mol Cell (2002) 3.65
The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1. Oncogene (2005) 3.64
Phosphoproteome analysis of the human mitotic spindle. Proc Natl Acad Sci U S A (2006) 3.56
Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle. J Cell Biol (2004) 3.49
Cell cycle regulation of central spindle assembly. Nature (2004) 3.27
HURP is a Ran-importin beta-regulated protein that stabilizes kinetochore microtubules in the vicinity of chromosomes. Curr Biol (2006) 3.21
Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis. J Cell Biol (2003) 3.12
Aurora kinases link chromosome segregation and cell division to cancer susceptibility. Curr Opin Genet Dev (2004) 2.96
CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging. Nat Methods (2010) 2.93
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Control of centriole length by CPAP and CP110. Curr Biol (2009) 2.67
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Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication. EMBO J (2002) 2.41
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Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity. J Cell Biol (2007) 1.59
Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells. Cell Motil Cytoskeleton (2004) 1.59
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Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity. Genes Dev (2005) 1.57
Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication. J Cell Sci (2013) 1.55
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Tubulin polyglutamylation stimulates spastin-mediated microtubule severing. J Cell Biol (2010) 1.49
Kinetic framework of spindle assembly checkpoint signalling. Nat Cell Biol (2013) 1.47
Aurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic process. J Biol Chem (2002) 1.47
A complex of two centrosomal proteins, CAP350 and FOP, cooperates with EB1 in microtubule anchoring. Mol Biol Cell (2005) 1.45
Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1. J Cell Sci (2010) 1.42
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Centrosome-associated NDR kinase regulates centrosome duplication. Mol Cell (2007) 1.37
Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis. J Cell Biol (2005) 1.34
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Kinetochore localization and microtubule interaction of the human spindle checkpoint kinase Mps1. Chromosoma (2004) 1.30
Sgt1 is required for human kinetochore assembly. EMBO Rep (2004) 1.30
The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis. J Cell Biol (2009) 1.29