Published in Angew Chem Int Ed Engl on January 01, 2009
The cancer glycocalyx mechanically primes integrin-mediated growth and survival. Nature (2014) 1.96
Glycan microarrays for decoding the glycome. Annu Rev Biochem (2011) 1.81
The role of flexibility in the rational design of modularly assembled ligands targeting the RNAs that cause the myotonic dystrophies. Chembiochem (2010) 1.13
Investigating cell surface galectin-mediated cross-linking on glycoengineered cells. J Am Chem Soc (2012) 1.02
Glycopolymer probes of signal transduction. Chem Soc Rev (2013) 0.98
End-functionalized glycopolymers as mimetics of chondroitin sulfate proteoglycans. Chem Sci (2010) 0.97
Synthesis of glycopolymers for microarray applications via ligation of reducing sugars to a poly(acryloyl hydrazide) scaffold. J Am Chem Soc (2010) 0.97
Density variant glycan microarray for evaluating cross-linking of mucin-like glycoconjugates by lectins. J Am Chem Soc (2012) 0.93
Deciphering structural elements of mucin glycoprotein recognition. ACS Chem Biol (2012) 0.92
Bishydrazide glycoconjugates for lectin recognition and capture of bacterial pathogens. Bioconjug Chem (2010) 0.87
Control of the molecular orientation of membrane-anchored biomimetic glycopolymers. J Am Chem Soc (2009) 0.87
Chemistry of natural glycan microarrays. Curr Opin Chem Biol (2014) 0.86
Determination of receptor specificities for whole influenza viruses using multivalent glycan arrays. Chem Commun (Camb) (2015) 0.86
Realizing the Promise of Chemical Glycobiology. Chem Sci (2013) 0.82
Chemoselective immobilization of proteins by microcontact printing and bio-orthogonal click reactions. Chembiochem (2013) 0.82
Enhanced microcontact printing of proteins on nanoporous silica surface. Nanotechnology (2010) 0.79
Cell and Protein Recognition at a Supported Bilayer Interface via In Situ Cavitand-Mediated Functional Polymer Growth. Langmuir (2015) 0.77
A Detailed Study on Understanding Glycopolymer Library and Con A Interactions. J Polym Sci A Polym Chem (2013) 0.76
Multi-dimensional glycan microarrays with glyco-macroligands. Glycoconj J (2015) 0.76
Assessing Bacterial Interactions Using Carbohydrate-Based Microarrays. Microarrays (Basel) (2015) 0.75
Click Chemistry: Diverse Chemical Function from a Few Good Reactions. Angew Chem Int Ed Engl (2001) 19.25
Biological roles of oligosaccharides: all of the theories are correct. Glycobiology (1993) 12.38
Printed covalent glycan array for ligand profiling of diverse glycan binding proteins. Proc Natl Acad Sci U S A (2004) 7.55
Glycan topology determines human adaptation of avian H5N1 virus hemagglutinin. Nat Biotechnol (2008) 4.37
Carbohydrate microarrays for the recognition of cross-reactive molecular markers of microbes and host cells. Nat Biotechnol (2002) 3.09
Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands. Nature (2000) 2.94
Influencing receptor-ligand binding mechanisms with multivalent ligand architecture. J Am Chem Soc (2002) 2.94
The cluster glycoside effect. Chem Rev (2002) 2.79
Carbohydrate arrays for the evaluation of protein binding and enzymatic modification. Chem Biol (2002) 2.49
Glycan array screening reveals a candidate ligand for Siglec-8. J Biol Chem (2004) 2.24
Oligosaccharide and glycoprotein microarrays as tools in HIV glycobiology; glycan-dependent gp120/protein interactions. Chem Biol (2004) 2.22
Oligosaccharide microarrays for high-throughput detection and specificity assignments of carbohydrate-protein interactions. Nat Biotechnol (2002) 2.21
Synthesis of sugar arrays in microtiter plate. J Am Chem Soc (2002) 1.96
The chemistry and biology of mucin-type O-linked glycosylation. Bioorg Med Chem (2005) 1.78
A carbohydrate-antioxidant hybrid polymer reduces oxidative damage in spermatozoa and enhances fertility. Nat Chem Biol (2005) 1.52
Quantitative analysis of carbohydrate-protein interactions using glycan microarrays: determination of surface and solution dissociation constants. J Am Chem Soc (2007) 1.52
Carbohydrate and protein immobilization onto solid surfaces by sequential Diels-Alder and azide-alkyne cycloadditions. Bioconjug Chem (2006) 1.51
Effects of clustered epitopes in multivalent ligand-receptor interactions. Biochemistry (2008) 1.48
Control of multivalent interactions by binding epitope density. J Am Chem Soc (2002) 1.46
Synthesis of end-labeled multivalent ligands for exploring cell-surface-receptor-ligand interactions. Chem Biol (2000) 1.45
Synthesis of neoglycopolymers by a combination of "click chemistry" and living radical polymerization. J Am Chem Soc (2006) 1.43
Versatile fluorescent derivatization of glycans for glycomic analysis. Nat Methods (2005) 1.41
Noncovalent cell surface engineering: incorporation of bioactive synthetic glycopolymers into cellular membranes. J Am Chem Soc (2008) 1.41
Covalent display of oligosaccharide arrays in microtiter plates. J Am Chem Soc (2004) 1.40
Neuroactive chondroitin sulfate glycomimetics. J Am Chem Soc (2008) 1.39
Nonstatistical binding of a protein to clustered carbohydrates. Proc Natl Acad Sci U S A (1999) 1.34
Glycan microarray of Globo H and related structures for quantitative analysis of breast cancer. Proc Natl Acad Sci U S A (2008) 1.33
Polyacrylamide-based glycoconjugates as tools in glycobiology. Glycoconj J (1998) 1.27
Interfacing carbon nanotubes with living cells. J Am Chem Soc (2006) 1.25
Carbohydrate-protein interactions by "clicked" carbohydrate self-assembled monolayers. Anal Chem (2006) 1.20
Synthesis of oxime-linked mucin mimics containing the tumor-related T(N) and sialyl T(N) antigens. Org Lett (2001) 1.18
Carbohydrate chips for studying high-throughput carbohydrate-protein interactions. J Am Chem Soc (2004) 1.14
Selective immobilization of multivalent ligands for surface plasmon resonance and fluorescence microscopy. Anal Biochem (2002) 1.12
Carbohydrate microarrays for assaying galactosyltransferase activity. Org Lett (2007) 1.11
"Click" chemistry by microcontact printing. Angew Chem Int Ed Engl (2006) 1.09
Carbohydrate microarrays by microcontact "click" chemistry. Langmuir (2008) 1.04
GlycoChip: multiarray for the study of carbohydrate-binding proteins. Lab Chip (2003) 1.04
Synthetic glycoprotein mimics inhibit L-selectin-mediated rolling and promote L-selectin shedding. Chem Biol (2004) 1.00
Serum antibody screening by surface plasmon resonance using a natural glycan microarray. Glycoconj J (2008) 1.00
A glycopolymer chaperone for fibroblast growth factor-2. Bioconjug Chem (2004) 0.97
Multivalent carbohydrate recognition on a glycodendrimer-functionalized flow-through chip. Chembiochem (2008) 0.97
Hierarchical assembly of model cell surfaces: synthesis of mucin mimetic polymers and their display on supported bilayers. J Am Chem Soc (2007) 0.96
Biomimetic engineering of carbon nanotubes by using cell surface mucin mimics. Angew Chem Int Ed Engl (2004) 0.95
Molecular orientation of membrane-anchored mucin glycoprotein mimics. J Phys Chem B (2007) 0.81
Copper-free click chemistry for dynamic in vivo imaging. Proc Natl Acad Sci U S A (2007) 8.50
Bioorthogonal chemistry: fishing for selectivity in a sea of functionality. Angew Chem Int Ed Engl (2009) 8.15
Chemistry in living systems. Nat Chem Biol (2005) 7.55
A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems. J Am Chem Soc (2004) 7.51
Glycans in cancer and inflammation--potential for therapeutics and diagnostics. Nat Rev Drug Discov (2005) 6.14
In vivo imaging of membrane-associated glycans in developing zebrafish. Science (2008) 5.45
Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation. Proc Natl Acad Sci U S A (2001) 4.88
Chemical remodelling of cell surfaces in living animals. Nature (2004) 4.86
A comparative study of bioorthogonal reactions with azides. ACS Chem Biol (2006) 4.26
Cu-free click cycloaddition reactions in chemical biology. Chem Soc Rev (2010) 3.89
Second-generation difluorinated cyclooctynes for copper-free click chemistry. J Am Chem Soc (2008) 3.65
Redirecting lipoic acid ligase for cell surface protein labeling with small-molecule probes. Nat Biotechnol (2007) 3.41
A chemical approach for identifying O-GlcNAc-modified proteins in cells. Proc Natl Acad Sci U S A (2003) 2.97
Copper-free click chemistry in living animals. Proc Natl Acad Sci U S A (2010) 2.76
Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones. J Am Chem Soc (2010) 2.74
Introducing genetically encoded aldehydes into proteins. Nat Chem Biol (2007) 2.65
MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence. Proc Natl Acad Sci U S A (2003) 2.62
Imaging the glycome. Proc Natl Acad Sci U S A (2008) 2.62
A metabolic labeling approach toward proteomic analysis of mucin-type O-linked glycosylation. Proc Natl Acad Sci U S A (2003) 2.56
From mechanism to mouse: a tale of two bioorthogonal reactions. Acc Chem Res (2011) 2.50
The glycosylphosphatidylinositol anchor: a complex membrane-anchoring structure for proteins. Biochemistry (2008) 2.40
Investigating cellular metabolism of synthetic azidosugars with the Staudinger ligation. J Am Chem Soc (2002) 2.26
Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis. Nat Struct Mol Biol (2004) 2.25
Discovery of aminoacyl-tRNA synthetase activity through cell-surface display of noncanonical amino acids. Proc Natl Acad Sci U S A (2006) 2.23
Mechanistic investigation of the staudinger ligation. J Am Chem Soc (2005) 2.19
Chemical technologies for probing glycans. Cell (2006) 2.04
A cell nanoinjector based on carbon nanotubes. Proc Natl Acad Sci U S A (2007) 2.00
Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling. Proc Natl Acad Sci U S A (2007) 1.98
Metabolic labeling of glycans with azido sugars for visualization and glycoproteomics. Methods Enzymol (2006) 1.93
Probing mucin-type O-linked glycosylation in living animals. Proc Natl Acad Sci U S A (2006) 1.85
A hydrophilic azacyclooctyne for Cu-free click chemistry. Org Lett (2008) 1.84
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag. Proc Natl Acad Sci U S A (2009) 1.83
Programmed assembly of 3-dimensional microtissues with defined cellular connectivity. Proc Natl Acad Sci U S A (2009) 1.83
Cholesterol catabolism by Mycobacterium tuberculosis requires transcriptional and metabolic adaptations. Chem Biol (2012) 1.79
A FRET-based fluorogenic phosphine for live-cell imaging with the Staudinger ligation. Angew Chem Int Ed Engl (2008) 1.79
The chemistry and biology of mucin-type O-linked glycosylation. Bioorg Med Chem (2005) 1.78
Deconvoluting the functions of polypeptide N-alpha-acetylgalactosaminyltransferase family members by glycopeptide substrate profiling. Chem Biol (2004) 1.78
Visualizing enveloping layer glycans during zebrafish early embryogenesis. Proc Natl Acad Sci U S A (2010) 1.74
Sulfotransferases and sulfatases in mycobacteria. Chem Biol (2002) 1.74
Integrated microfluidic bioprocessor for single-cell gene expression analysis. Proc Natl Acad Sci U S A (2008) 1.73
Metabolic labeling of glycans with azido sugars and subsequent glycan-profiling and visualization via Staudinger ligation. Nat Protoc (2007) 1.73
Imaging cell surface glycans with bioorthogonal chemical reporters. J Am Chem Soc (2007) 1.65
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter. Proc Natl Acad Sci U S A (2010) 1.63
Metabolic cross-talk allows labeling of O-linked beta-N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway. Proc Natl Acad Sci U S A (2011) 1.61
5'-Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice. Mol Microbiol (2006) 1.59
Site-specific antibody-drug conjugates: the nexus of bioorthogonal chemistry, protein engineering, and drug development. Bioconjug Chem (2015) 1.58
Symbol nomenclature for glycan representation. Proteomics (2009) 1.56
Sulfate metabolism in mycobacteria. Chembiochem (2006) 1.55
Identification of palmitoylated mitochondrial proteins using a bio-orthogonal azido-palmitate analogue. FASEB J (2007) 1.55
Metabolic labeling of sialic acids in living animals with alkynyl sugars. Angew Chem Int Ed Engl (2009) 1.53
Copper-free click chemistry for the in situ crosslinking of photodegradable star polymers. Chem Commun (Camb) (2008) 1.52
In vivo imaging of Caenorhabditis elegans glycans. ACS Chem Biol (2009) 1.48
Bringing chemistry to life. Nat Methods (2011) 1.45
Trehalose is required for growth of Mycobacterium smegmatis. J Biol Chem (2004) 1.44
Substrate recognition, protein dynamics, and iron-sulfur cluster in Pseudomonas aeruginosa adenosine 5'-phosphosulfate reductase. J Mol Biol (2006) 1.42
Noncovalent cell surface engineering: incorporation of bioactive synthetic glycopolymers into cellular membranes. J Am Chem Soc (2008) 1.41
Metabolic oligosaccharide engineering as a tool for glycobiology. Curr Opin Chem Biol (2003) 1.41
Site-specific chemical protein conjugation using genetically encoded aldehyde tags. Nat Protoc (2012) 1.40
Programmable cell adhesion encoded by DNA hybridization. Angew Chem Int Ed Engl (2006) 1.39
Selective enrichment of azide-containing peptides from complex mixtures. J Proteome Res (2009) 1.38
Compositional profiling of heparin/heparan sulfate using mass spectrometry: assay for specificity of a novel extracellular human endosulfatase. Glycobiology (2005) 1.35
A chemical reporter strategy to probe glycoprotein fucosylation. J Am Chem Soc (2006) 1.35
Function and structure of a prokaryotic formylglycine-generating enzyme. J Biol Chem (2008) 1.35
A conserved mechanism for sulfonucleotide reduction. PLoS Biol (2005) 1.34
Membrane proteomics of phagosomes suggests a connection to autophagy. Proc Natl Acad Sci U S A (2008) 1.34
Spontaneous assembly of viruses on multilayered polymer surfaces. Nat Mater (2006) 1.33
Chemical approaches to perturb, profile, and perceive glycans. Acc Chem Res (2009) 1.33
A decade of bioorthogonal chemistry. Acc Chem Res (2011) 1.32
Boron nitride nanotubes are noncytotoxic and can be functionalized for interaction with proteins and cells. J Am Chem Soc (2009) 1.31
Rapid detection, discovery, and identification of post-translationally myristoylated proteins during apoptosis using a bio-orthogonal azidomyristate analog. FASEB J (2007) 1.31
Direct cell surface modification with DNA for the capture of primary cells and the investigation of myotube formation on defined patterns. Langmuir (2009) 1.30
(D)-Amino acid chemical reporters reveal peptidoglycan dynamics of an intracellular pathogen. ACS Chem Biol (2013) 1.29
Difluorobenzocyclooctyne: synthesis, reactivity, and stabilization by beta-cyclodextrin. J Am Chem Soc (2010) 1.29
Synthetic riboswitches that induce gene expression in diverse bacterial species. Appl Environ Microbiol (2010) 1.29
A fluorogenic dye activated by the staudinger ligation. J Am Chem Soc (2003) 1.29
Expanding the diversity of unnatural cell-surface sialic acids. Chembiochem (2004) 1.29
5'-adenosinephosphosulfate lies at a metabolic branch point in mycobacteria. J Biol Chem (2002) 1.27
Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach. Proc Natl Acad Sci U S A (2002) 1.26
Metabolic labeling of fucosylated glycans in developing zebrafish. ACS Chem Biol (2011) 1.25
Synthesis of heterobifunctional protein fusions using copper-free click chemistry and the aldehyde tag. Angew Chem Int Ed Engl (2012) 1.25
PapA1 and PapA2 are acyltransferases essential for the biosynthesis of the Mycobacterium tuberculosis virulence factor sulfolipid-1. Proc Natl Acad Sci U S A (2007) 1.25
Interfacing carbon nanotubes with living cells. J Am Chem Soc (2006) 1.25
Reactivity of biarylazacyclooctynones in copper-free click chemistry. J Am Chem Soc (2012) 1.24
An inhibitor of the human UDP-GlcNAc 4-epimerase identified from a uridine-based library: a strategy to inhibit O-linked glycosylation. Chem Biol (2002) 1.22
Rapid and selective detection of fatty acylated proteins using omega-alkynyl-fatty acids and click chemistry. J Lipid Res (2009) 1.20
Metabolic functionalization of recombinant glycoproteins. Biochemistry (2004) 1.19
Synthesis, characterization, and theory of [9]-, [12]-, and [18]cycloparaphenylene: carbon nanohoop structures. J Am Chem Soc (2008) 1.19
A new approach to mineralization of biocompatible hydrogel scaffolds: an efficient process toward 3-dimensional bonelike composites. J Am Chem Soc (2003) 1.18
A chemical method for labeling lysine methyltransferase substrates. Chembiochem (2010) 1.18
A sulfated metabolite produced by stf3 negatively regulates the virulence of Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2006) 1.16
Synthetic glycopeptides and glycoproteins as tools for biology. Chem Soc Rev (2004) 1.16
Fluorophore targeting to cellular proteins via enzyme-mediated azide ligation and strain-promoted cycloaddition. J Am Chem Soc (2012) 1.15
The regulation of sulfur metabolism in Mycobacterium tuberculosis. PLoS Pathog (2011) 1.15
Probing glycosyltransferase activities with the Staudinger ligation. J Am Chem Soc (2004) 1.15
The roles of enzyme localisation and complex formation in glycan assembly within the Golgi apparatus. Curr Opin Cell Biol (2004) 1.15
Drug targeting Mycobacterium tuberculosis cell wall synthesis: development of a microtiter plate-based screen for UDP-galactopyranose mutase and identification of an inhibitor from a uridine-based library. Antimicrob Agents Chemother (2003) 1.14
Imaging bacterial peptidoglycan with near-infrared fluorogenic azide probes. Proc Natl Acad Sci U S A (2014) 1.14