Published in Dev Dyn on July 01, 2009
Protein O-fucosyltransferase 1 (Pofut1) regulates lymphoid and myeloid homeostasis through modulation of Notch receptor ligand interactions. Blood (2011) 1.24
Notch signaling during cell fate determination in the inner ear. Semin Cell Dev Biol (2013) 0.97
Role of glycans and glycosyltransferases in the regulation of Notch signaling. Glycobiology (2010) 0.97
Slc35c2 promotes Notch1 fucosylation and is required for optimal Notch signaling in mammalian cells. J Biol Chem (2010) 0.95
A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins. Glycobiology (2012) 0.94
Deciphering the Fringe-Mediated Notch Code: Identification of Activating and Inhibiting Sites Allowing Discrimination between Ligands. Dev Cell (2016) 0.85
Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol (2015) 0.85
Lunatic, Manic, and Radical Fringe Each Promote T and B Cell Development. J Immunol (2015) 0.78
Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates. Elife (2016) 0.78
The multiple roles of epidermal growth factor repeat O-glycans in animal development. Glycobiology (2015) 0.77
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Fringe is a glycosyltransferase that modifies Notch. Nature (2000) 4.09
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Glycosyltransferase activity of Fringe modulates Notch-Delta interactions. Nature (2000) 3.51
A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency. Development (2002) 2.88
Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2. Nat Cell Biol (2000) 2.83
Defects in somite formation in lunatic fringe-deficient mice. Nature (1998) 2.37
Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum. Development (1994) 2.33
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Mouse duplicate genes are as essential as singletons. Trends Genet (2007) 2.12
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Lunatic and manic fringe cooperatively enhance marginal zone B cell precursor competition for delta-like 1 in splenic endothelial niches. Immunity (2009) 2.03
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The mouse Engrailed-1 gene and ventral limb patterning. Nature (1996) 1.98
A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway. Development (1997) 1.74
Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation. J Exp Med (2007) 1.73
Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1. Mol Biol Cell (2004) 1.71
Lunatic fringe null female mice are infertile due to defects in meiotic maturation. Development (2005) 1.69
Regulation of T lymphopoiesis by Notch1 and Lunatic fringe-mediated competition for intrathymic niches. Nat Immunol (2006) 1.57
Expression of Radical fringe in limb-bud ectoderm regulates apical ectodermal ridge formation. Nature (1997) 1.52
Fringe modifies O-fucose on mouse Notch1 at epidermal growth factor-like repeats within the ligand-binding site and the Abruptex region. J Biol Chem (2002) 1.41
Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1. Immunity (2001) 1.41
Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb. Nature (1997) 1.33
Regions of Drosophila Notch that contribute to ligand binding and the modulatory influence of Fringe. J Biol Chem (2005) 1.30
Manic fringe and lunatic fringe modify different sites of the Notch2 extracellular region, resulting in different signaling modulation. J Biol Chem (2001) 1.23
Notch activation regulates the segregation and differentiation of rhombomere boundary cells in the zebrafish hindbrain. Dev Cell (2004) 1.20
Fringe boundaries coincide with Notch-dependent patterning centres in mammals and alter Notch-dependent development in Drosophila. Nat Genet (1997) 1.19
Lunatic fringe, manic fringe, and radical fringe recognize similar specificity determinants in O-fucosylated epidermal growth factor-like repeats. J Biol Chem (2005) 1.18
Analysis of the genetic pathway leading to formation of ectopic apical ectodermal ridges in mouse Engrailed-1 mutant limbs. Development (1998) 1.16
Modulation of notch signaling during somitogenesis. Annu Rev Cell Dev Biol (2003) 1.15
Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant mice. Genesis (2002) 1.14
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Limbs move beyond the radical fringe. Nature (1999) 1.07
Oscillatory lunatic fringe activity is crucial for segmentation of the anterior but not posterior skeleton. Development (2008) 1.05
Bile duct proliferation in Jag1/fringe heterozygous mice identifies candidate modifiers of the Alagille syndrome hepatic phenotype. Hepatology (2008) 1.02
Segmental and neuronal architecture of the hindbrain of Krox-20 mouse mutants. Development (1997) 0.97
The chick limbless mutation causes abnormalities in limb bud dorsal-ventral patterning: implications for the mechanism of apical ridge formation. Development (1996) 0.94
MFng is dispensable for mouse pancreas development and function. Mol Cell Biol (2009) 0.89
A deficiency of lunatic fringe is associated with cystic dilation of the rete testis. Reproduction (2008) 0.87
Of chicken wings and frog legs: a smorgasbord of evolutionary variation in mechanisms of tetrapod limb development. Dev Biol (2005) 0.86
Lunatic fringe protein processing by proprotein convertases may contribute to the short protein half-life in the segmentation clock. Biochim Biophys Acta (2008) 0.85
The knockout mouse project. Nat Genet (2004) 7.80
Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. N Engl J Med (2016) 3.88
Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genes. Genes Dev (2006) 3.30
CTCF maintains differential methylation at the Igf2/H19 locus. Nat Genet (2002) 3.15
Rapid production of gene replacement constructs and generation of a green fluorescent protein-tagged centromeric marker in Aspergillus nidulans. Eukaryot Cell (2004) 2.41
Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice. Proc Natl Acad Sci U S A (2002) 2.03
Many roads lead to primary autosomal recessive microcephaly. Prog Neurobiol (2009) 1.78
NOTCH1 mutations in individuals with left ventricular outflow tract malformations reduce ligand-induced signaling. Hum Mol Genet (2008) 1.37
The endothelin receptor-B is required for the migration of neural crest-derived melanocyte and enteric neuron precursors. Dev Biol (2003) 1.32
Biomedical waste management in nursing homes and smaller hospitals in Delhi. Waste Manag (2008) 1.20
Fibulin-3 promotes glioma growth and resistance through a novel paracrine regulation of Notch signaling. Cancer Res (2012) 1.17
Growth-associated protein-43 is required for commissural axon guidance in the developing vertebrate nervous system. J Neurosci (2002) 1.16
Clock regulatory elements control cyclic expression of Lunatic fringe during somitogenesis. Dev Cell (2002) 1.10
Stem cell therapy for neonatal brain injury: perspectives and challenges. Ann Neurol (2011) 1.05
Oscillatory lunatic fringe activity is crucial for segmentation of the anterior but not posterior skeleton. Development (2008) 1.05
Bile duct proliferation in Jag1/fringe heterozygous mice identifies candidate modifiers of the Alagille syndrome hepatic phenotype. Hepatology (2008) 1.02
What's the hype about CDK5RAP2? Cell Mol Life Sci (2011) 1.02
Cardiac outflow tract septation failure in Pax3-deficient embryos is due to p53-dependent regulation of migrating cardiac neural crest. Mech Dev (2008) 0.99
PDK1 attenuation fails to prevent tumor formation in PTEN-deficient transgenic mouse models. Cancer Res (2011) 0.99
Sizzled-tolloid interactions maintain foregut progenitors by regulating fibronectin-dependent BMP signaling. Dev Cell (2012) 0.95
Expression of Sonic hedgehog during cell proliferation in the human cerebellum. Stem Cells Dev (2011) 0.95
A 178-kb BAC transgene imprints the mouse Gtl2 gene and localizes tissue-specific regulatory elements. Genomics (2004) 0.93
Molecular genetic analysis of the glycosyltransferase Fringe in Drosophila. Proc Natl Acad Sci U S A (2003) 0.92
Dual role of Nr2e3 in photoreceptor development and maintenance. Exp Eye Res (2008) 0.91
Coordination between extrinsic extracellular matrix cues and intrinsic responses to orient the centrosome in polarizing cerebellar granule neurons. J Neurosci (2010) 0.90
Neurospheres derived from human embryoid bodies treated with retinoic Acid show an increase in nestin and ngn2 expression that correlates with the proportion of tyrosine hydroxylase-positive cells. Stem Cells Dev (2007) 0.90
Inhibition of retinal and choroidal neovascularization by a novel KDR kinase inhibitor. Mol Vis (2005) 0.90
Interrogating a hexokinase-selected small-molecule library for inhibitors of Plasmodium falciparum hexokinase. Antimicrob Agents Chemother (2013) 0.90
Diacylglycerol acyltransferase-1 (DGAT1) inhibition perturbs postprandial gut hormone release. PLoS One (2013) 0.89
Functional characterization of a novel Ku70/80 pause site at the H19/Igf2 imprinting control region. Mol Cell Biol (2005) 0.89
GAP-43 is key to mitotic spindle control and centrosome-based polarization in neurons. Cell Cycle (2007) 0.88
Dynamic expression patterns of Nkx6.1 and Nkx6.2 in the developing mes-diencephalic basal plate. Dev Dyn (2010) 0.88
Optimized derivation and functional characterization of 5-HT neurons from human embryonic stem cells. Stem Cells Dev (2009) 0.87
AAV8-mediated long-term expression of human LCAT significantly improves lipid profiles in hCETP;Ldlr(+/-) mice. J Cardiovasc Transl Res (2011) 0.87
Failure to express GAP-43 leads to disruption of a multipotent precursor and inhibits astrocyte differentiation. Mol Cell Neurosci (2004) 0.86
Demonstration of diet-induced decoupling of fatty acid and cholesterol synthesis by combining gene expression array and 2H2O quantification. Am J Physiol Endocrinol Metab (2011) 0.86
The vertebrate segmentation clock and its role in skeletal birth defects. Birth Defects Res C Embryo Today (2007) 0.85
Functional characterization of a testis-specific DNA binding activity at the H19/Igf2 imprinting control region. Mol Cell Biol (2003) 0.85
Preterm delivery disrupts the developmental program of the cerebellum. PLoS One (2011) 0.85
Lunatic fringe protein processing by proprotein convertases may contribute to the short protein half-life in the segmentation clock. Biochim Biophys Acta (2008) 0.85
Both cell-autonomous and cell non-autonomous functions of GAP-43 are required for normal patterning of the cerebellum in vivo. Cerebellum (2008) 0.84
NRSF downregulation induces neuronal differentiation in mouse embryonic stem cells. Differentiation (2008) 0.83
Meiotic functions of RAD18. J Cell Sci (2011) 0.83
Prevalence of herbal and dietary supplement usage in Thai outpatients with chronic kidney disease: a cross-sectional survey. BMC Complement Altern Med (2013) 0.83
CMV promotor activity during ES cell differentiation: potential insight into embryonic stem cell differentiation. Cell Biol Int (2006) 0.82
A Molecular atlas of Xenopus respiratory system development. Dev Dyn (2014) 0.82
Conditional induction of Math1 specifies embryonic stem cells to cerebellar granule neuron lineage and promotes differentiation into mature granule neurons. Stem Cells (2013) 0.82
Mir-125a-5p-mediated regulation of Lfng is essential for the avian segmentation clock. Dev Cell (2013) 0.81
VIP blockade leads to microcephaly in mice via disruption of Mcph1-Chk1 signaling. J Clin Invest (2011) 0.81
Heterozygous disruption of renal outer medullary potassium channel in rats is associated with reduced blood pressure. Hypertension (2013) 0.81
Pleiotrophin is an important regulator of the renin-angiotensin system in mouse aorta. Biochem Biophys Res Commun (2004) 0.79
NOTCH1 missense alleles associated with left ventricular outflow tract defects exhibit impaired receptor processing and defective EMT. Biochim Biophys Acta (2010) 0.79
The AMPA receptor positive allosteric modulator, S18986, is neuroprotective against neonatal excitotoxic and inflammatory brain damage through BDNF synthesis. Neuropharmacology (2009) 0.78
In vitro induction of neural differentiation of embryonic stem (ES) cells closely mimics molecular mechanisms of embryonic brain development. Pediatr Res (2006) 0.77
Early protein malnutrition disrupts cerebellar development and impairs motor coordination. Br J Nutr (2011) 0.77
Spatial memory deficits in maternal iron deficiency paradigms are associated with altered glucocorticoid levels. Horm Behav (2013) 0.77
Pleiotrophin is a major regulator of the catecholamine biosynthesis pathway in mouse aorta. Biochem Biophys Res Commun (2004) 0.77
Multiple Dlk1 splice variants are expressed during early mouse embryogenesis. Int J Dev Biol (2014) 0.76
Expression of a modified H19 RNA does not cause embryonic lethality in mice. Mamm Genome (2006) 0.76
Growth and differentiation factor 10 (Gdf10) is involved in Bergmann glial cell development under Shh regulation. Glia (2014) 0.76
In vivo analysis of gene knockdown in tetracycline-inducible shRNA mice. Methods Enzymol (2010) 0.75
Expression and characterization of penicillin-binding proteins in Burkholderia cenocepacia. Curr Microbiol (2009) 0.75