Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoire.

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Published in Proc Natl Acad Sci U S A on June 18, 2009

Authors

H Hamlet Chu1, James J Moon, Kensuke Takada, Marion Pepper, Jerry A Molitor, Timothy W Schacker, Kristin A Hogquist, Stephen C Jameson, Marc K Jenkins

Author Affiliations

1: Department of Microbiology, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.

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