Published in J Exp Med on June 01, 1978
Cellular and genetic control of antibody responses. V. Helper T-cell recognition of H-2 determinants on accessory cells but not B cells. J Exp Med (1979) 2.75
Self recognition in allogeneic radiation bone marrow chimeras. A radiation-resistant host element dictates the self specificity and immune response gene phenotype of T-helper cells. J Exp Med (1981) 2.39
Biochemical characterization of a second family of human Ia molecules, HLA-DS, equivalent to murine I-A subregion molecules. J Exp Med (1982) 2.15
The role of H-2 linked genes in helper T-cell function. IV. Importance of T-cell genotype and host environment in I-region and Ir gene expression. J Exp Med (1978) 2.00
The role of H-2-linked genes in helper T-cell function. VI. Expression of Ir genes by helper T cells. J Exp Med (1979) 1.33
Characterization of antigen-specific, Ia-restricted, L3T4+ cytolytic T lymphocytes and assessment of thymic influence on their self specificity. J Exp Med (1985) 1.26
Cytotoxic T lymphocyte responses in allogeneic radiation bone marrow chimeras. The chimeric host strictly dictates the self-repertoire of Ia-restricted T cells but not H-2K/D-restricted T cells. J Exp Med (1982) 1.24
Nature of T-cell macrophage interaction in helper-cell induction in vitro. II. Two stages of T-helper-cell differentiation analyzed in irradiation and allophenic chimeras. J Exp Med (1979) 1.20
Genetic control of the immune response to collagen. II. Antibody responses produced in fetal liver restored radiation chimeras and thymus reconstituted F1 hybrid nude mice. J Exp Med (1979) 1.15
Positive selection of T-lymphocytes induced by intrathymic injection of a thymic epithelial cell line. Nature (1992) 1.15
Subpopulations of B cells distinguished by cell surface expression of Ia antigens. Correlation of Ia and idiotype during activation by cloned Ia-restricted T cells. J Exp Med (1983) 1.13
Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoire. Proc Natl Acad Sci U S A (2009) 1.09
T cell regulation of B cell activation. I-A-restricted T suppressor cells inhibit the major histocompatibility complex-restricted interactions of T helper cells with B cells and accessory cells. J Exp Med (1983) 1.06
Antigenic marker on a functional subpopulation of B cells, controlled by the I-A subregion of the H-2 complex. Proc Natl Acad Sci U S A (1979) 1.00
Restricted antibody formation to sheep erythrocytes of allogeneic bone marrow chimeras histoincompatible at the K end of the H-2 complex. J Exp Med (1981) 0.99
Antigen-specific helper T cells required for dominant production of an idiotype (THId) are not under immune response (Ir) gene control. J Exp Med (1980) 0.90
Lymphoid function in F1 leads to parent chimeras: lack of evidence for adaptive differentiation of B cells or antigen-presenting cells. J Exp Med (1979) 0.89
T-helper function of parent leads to F1 chimeras. Presence of a separate T-cell subgroup able to stimulate allogeneic B cells but not syngeneic B cells. J Exp Med (1979) 0.85
Structural analysis of a new B-cell-differentiation antigen associated with products of the I-A subregion of the H-2 complex. Proc Natl Acad Sci U S A (1981) 0.83
Cyclosporin A and anti-Ia antibody cause a maturation defect of CD4+8- cells in organ-cultured fetal thymus. Immunology (1989) 0.83
Antigen-specific helper T cells required for dominant idiotype expression are not H-2 restricted. J Exp Med (1981) 0.81
Genetic control of the immune response to myoglobins. Both low and high responder T cells tolerant to the other major histocompatibility complex help high but not low responder B cells. J Exp Med (1982) 0.79
The molecular jury: deciding whether immature thymocytes should live or die. J Exp Med (1996) 0.75
B lymphocyte immune response gene phenotype is genetically determined. J Exp Med (1982) 0.75
A rapid method for the isolation of functional thymus-derived murine lymphocytes. Eur J Immunol (1973) 45.44
On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition? J Exp Med (1978) 9.51
H-2 dependence of co-operation between T and B cells in vivo. J Immunol (1972) 5.10
The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help. J Exp Med (1978) 4.27
Collaboration of allogeneic T and B lymphocytes in the primary antibody response to sheep erythrocytes in vitro. J Exp Med (1975) 2.30
T cell function in bone marrow chimeras: absence of host-reactive T cells and cooperation of helper T cells across allogeneic barriers. Transplant Rev (1976) 1.49
Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15. Immunity (1998) 9.02
Turnover of naive- and memory-phenotype T cells. J Exp Med (1994) 8.07
A receptor for antibody on B lymphocytes. I. Method of detection and functional significance. J Exp Med (1972) 7.47
Induction of bystander T cell proliferation by viruses and type I interferon in vivo. Science (1996) 7.00
IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc Natl Acad Sci U S A (2001) 6.91
Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity. Cell (1990) 6.33
T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature (1994) 6.20
A monoclonal antibody discriminating between subsets of T and B cells. J Immunol (1981) 6.15
The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. Immunity (1999) 6.10
Circulating T and B lymphocytes of the mouse. I. Migratory properties. Cell Immunol (1973) 3.53
Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice. Prevention by removing mature T cells from marrow. J Exp Med (1978) 3.46
Antigen-induced selective recruitment of circulating lymphocytes. Cell Immunol (1971) 3.35
Quantitative features of a sandwich radioimmunolabeling technique for lymphocyte surface receptors. J Exp Med (1972) 3.28
Cell-to-cell interaction in the immune response. VI. Contribution of thymus-derived cells and antibody-forming cell precursors to immunological memory. J Exp Med (1971) 3.14
Interaction between lymphocytes in immune responses. Cell Immunol (1971) 3.03
Collaboration of histoincompatible T and B lymphocytes using cells from tetraparental bone marrow chimeras. J Exp Med (1975) 3.03
T cell priming in vivo: a major role for B cells in presenting antigen to T cells in lymph nodes. J Immunol (1987) 2.93
Reentry of T cells to the adult thymus is restricted to activated T cells. J Exp Med (1991) 2.81
Properties of purified T cell subsets. I. In vitro responses to class I vs. class II H-2 alloantigens. J Exp Med (1985) 2.79
Cell-to-cell interaction in the immune response. X. T-cell-dependent suppression in tolerant mice. J Exp Med (1974) 2.77
TCR-Mediated internalization of peptide-MHC complexes acquired by T cells. Science (1999) 2.70
A defect in central tolerance in NOD mice. Nat Immunol (2001) 2.59
Type I interferon-mediated stimulation of T cells by CpG DNA. J Exp Med (1998) 2.58
Homeostatic T cell proliferation: how far can T cells be activated to self-ligands? J Exp Med (2000) 2.55
Association of immunity and tolerance to host H-2 determinants in irradiated F1 hybrid mice reconstituted with bone marrow cells from one parental strain. J Exp Med (1975) 2.39
Tolerance to histocompatibility determinants in tetraparental bone marrow chimeras. J Exp Med (1975) 2.29
Properties of purified T cell subsets. II. In vivo responses to class I vs. class II H-2 differences. J Exp Med (1986) 2.29
T cell stimulation in vivo by lipopolysaccharide (LPS). J Exp Med (1997) 2.29
Activation of thymus cells by histocompatibility antigens. Nat New Biol (1971) 2.26
Identity of cells that imprint H-2-restricted T-cell specificity in the thymus. Nature (1986) 2.11
Thymus-derived cells in mouse thoracic duct lymph. Nat New Biol (1971) 2.07
Role of H-2 gene products in the function of T helper cells from normal and chimeric mice in vivo. Immunol Rev (1978) 1.95
Circulating T and B lymphocytes of the mouse. II. Lifespan. Cell Immunol (1973) 1.94
Fate of H2-activated T lymphocytes in syngeneic hosts. I. Fate in lymphoid tissues and intestines traced with 3H-thymidine, 125I-deoxyuridine and 51chromium. Cell Immunol (1976) 1.89
T cells can use either T cell receptor or CD28 receptors to absorb and internalize cell surface molecules derived from antigen-presenting cells. J Exp Med (2000) 1.88
Receptor for antibody-antigen complexes used to separate T cells from B cells. Nat New Biol (1972) 1.87
A monoclonal antibody detecting an Ia specificity mapping in the I-A or I-E subregion. Immunogenetics (1981) 1.83
Surface immunoglobulins on thymus and thymus-derived lymphoid cells. J Exp Med (1971) 1.79
Interaction of thymus lymphocytes with histoincompatible cells. II. Recirculating lymphocytes derived from antigen-activated thymus cells. Cell Immunol (1972) 1.78
Negative selection in the thymus includes semimature T cells. J Exp Med (1997) 1.77
The generation of killer cells to trinitrophenyl-modified allogeneic targets by lymphocyte populations negatively selected to strong alloantigens. J Exp Med (1977) 1.75
Abnormal differentiation of thymocytes in mice treated with cyclosporin A. Nature (1988) 1.73
Requirements for peptide-induced T cell receptor downregulation on naive CD8+ T cells. J Exp Med (1997) 1.70
Interaction of thymus lymphocytes with histoincompatible cells. I. Quantitation of the proliferative response of thymus cells. Cell Immunol (1972) 1.68
Stimulation of mature unprimed CD8+ T cells by semiprofessional antigen-presenting cells in vivo. J Exp Med (1992) 1.61
Two subsets of epithelial cells in the thymic medulla. J Exp Med (1992) 1.59
Upregulation of surface markers on dying thymocytes. J Exp Med (1995) 1.59
Effects of blocking helper T cell induction in vivo with anti-Ia antibodies. Possible role of I-A/E hybrid molecules as restriction elements. J Exp Med (1980) 1.59
Effect of recent antigen priming on adoptive immune responses. I. Specific unresponsiveness of cells from lymphoid organs of mice primed with heterologous erythrocytes. J Exp Med (1973) 1.58
Capacity of unprimed CD4+ and CD8+ T cells expressing V beta 11 receptors to respond to I-E alloantigens in vivo. J Exp Med (1989) 1.58
Five types of lymphocytes (Ig-theta-, Ig-theta+weak, Ig-theta+strong, Ig+theta- and Ig+theta+) characterized by double immunofluorescence and electrophoretic mobility. Organ distribution in normal and nude mice. Eur J Immunol (1975) 1.54
Strong T cell tolerance in parent----F1 bone marrow chimeras prepared with supralethal irradiation. Evidence for clonal deletion and anergy. J Exp Med (1990) 1.54
Surface markers of T cells causing lethal graft-vs-host disease to class I vs class II H-2 differences. J Immunol (1985) 1.51
T cell function in bone marrow chimeras: absence of host-reactive T cells and cooperation of helper T cells across allogeneic barriers. Transplant Rev (1976) 1.49
Lifespan of gamma/delta T cells. J Exp Med (1998) 1.49
Interaction of thymus lymphocytes with histoincompatible cells. 3. Immunological characteristics of recirculating lymphocytes derived from activated thymus cells. Cell Immunol (1972) 1.49
Induction of neonatal tolerance to Mlsa antigens by CD8+ T cells. Science (1990) 1.47
Cell-to-cell interaction in the immune response. VII. Requirement for differentiation of thymus-derived cells. J Exp Med (1971) 1.46
DNA as an adjuvant: capacity of insect DNA and synthetic oligodeoxynucleotides to augment T cell responses to specific antigen. J Exp Med (1998) 1.41
Variable capacity of L3T4+ T cells to cause lethal graft-versus-host disease across minor histocompatibility barriers in mice. J Exp Med (1987) 1.41
Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection. Mucosal Immunol (2012) 1.39
An IFN-gamma-dependent pathway controls stimulation of memory phenotype CD8+ T cell turnover in vivo by IL-12, IL-18, and IFN-gamma. J Immunol (2001) 1.38
Transgenic HLA-DR alpha faithfully reconstitutes IE-controlled immune functions and induces cross-tolerance to E alpha in E alpha 0 mutant mice. Cell (1989) 1.37
Antigen-induced selective recruitment of circulating lymphocytes. 1971. J Immunol (2006) 1.37
Functions of purified L3T4+ and Lyt-2+ cells in vitro and in vivo. Immunol Rev (1986) 1.36
A novel class II MHC molecule with unusual tissue distribution. Nature (1991) 1.33
Fc-receptors, Ia-antigens, and immunoglobulin on normal and activated mouse T lymphocytes. J Exp Med (1975) 1.32
Radiosensitivity of T and B lymphocytes. I. Effect of irradiation on cell migration. Eur J Immunol (1974) 1.31
Thymus-grafted SCID mice show transient thymopoiesis and limited depletion of V beta 11+ T cells. J Exp Med (1992) 1.30
Thymic selection by a single MHC/peptide ligand produces a semidiverse repertoire of CD4+ T cells. Immunity (1997) 1.30
Effect of recent antigen priming on adoptive immune responses. III. Antigen-induced selective recruitment of subsets of recirculating lymphocytes reactive to H-2 determinants. J Exp Med (1976) 1.30
A role for Fas in negative selection of thymocytes in vivo. J Exp Med (1998) 1.30
Thymus-derived cells as killer cells in cell-mediated immunity. Transplant Proc (1971) 1.29
B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of V beta 5+ thymocytes. J Immunol (1994) 1.28
Capacity of purified Lyt-2+ T cells to mount primary proliferative and cytotoxic responses to Ia- tumour cells. Nature (1986) 1.26
Specific adsorption of IgM antibody onto H-2-activated mouse T lymphocytes. J Exp Med (1976) 1.26
Transfected Drosophila cells as a probe for defining the minimal requirements for stimulating unprimed CD8+ T cells. Proc Natl Acad Sci U S A (1996) 1.25
HIV results in the frame. CD4+ cell turnover. Nature (1995) 1.24
Stimulation of naïve and memory T cells by cytokines. Immunol Rev (1999) 1.23
Radiosensitivity of T and B lymphocytes. II. Effect of irradiation on response of T cells to alloantigens. Eur J Immunol (1974) 1.23
Several different cell surface molecules control negative selection of medullary thymocytes. J Exp Med (1999) 1.22
Viruses and T cell turnover: evidence for bystander proliferation. Immunol Rev (1996) 1.22
Growth of epithelial cells in the thymic medulla is under the control of mature T cells. J Exp Med (1992) 1.22
Features of T cells causing H-2-restricted lethal graft-vs.-host disease across minor histocompatibility barriers. J Exp Med (1982) 1.22
Antigen-presenting cells for unprimed T cells. Immunol Today (1989) 1.21
T cell subsets and graft-versus-host disease. Transplantation (1987) 1.19
Resting and activated T cells display different requirements for CD8 molecules. J Exp Med (1994) 1.19
B lymphocytes as stimulators of a mixed lymphocyte reaction. Transplantation (1973) 1.18
Tolerogenicity of thymic epithelium. Eur J Immunol (1990) 1.18
Restricted tissue distribution of Mlsa determinants. Stimulation of Mlsa-reactive T cells by B cells but not by dendritic cells or macrophages. J Exp Med (1989) 1.16
Cell-to-cell interaction in the immune response. 8. Radiosensitivity of thymus-derived lymphocytes. J Exp Med (1972) 1.16
Expression of M locus differences by B cells but not T cells. Nature (1974) 1.15
Differing roles for B7 and intercellular adhesion molecule-1 in negative selection of thymocytes. J Exp Med (1996) 1.14
Thymic selection and cell division. J Exp Med (1995) 1.14
Lifespan of lymphocytes. Immunol Res (1995) 1.14
Capacity of small B cell-enriched populations to stimulate mixed lymphocyte reactions: marked differences between irradiated vs. mitomycin C-treated stimulators. Eur J Immunol (1985) 1.14