Published in J Clin Endocrinol Metab on June 30, 2009
Fagopyrum tataricum (buckwheat) improved high-glucose-induced insulin resistance in mouse hepatocytes and diabetes in fructose-rich diet-induced mice. Exp Diabetes Res (2012) 0.85
Antihypertriglyceridemia and anti-inflammatory activities of monascus-fermented dioscorea in streptozotocin-induced diabetic rats. Exp Diabetes Res (2011) 0.84
Low circulating levels of IGF-1 in healthy adults are associated with reduced β-cell function, increased intramyocellular lipid, and enhanced fat utilization during fasting. J Clin Endocrinol Metab (2014) 0.77
Recombinant human growth hormone in treatment of diabetes: report of three cases and review of relative literature. Int J Clin Exp Med (2015) 0.75
Influences of glucose loading and of injected insulin on hepatic glucose output. Ann N Y Acad Sci (1959) 8.62
Mechanism of free fatty acid-induced insulin resistance in humans. J Clin Invest (1996) 6.50
Mechanisms of fatty acid-induced inhibition of glucose uptake. J Clin Invest (1994) 5.12
Effect of fatty acids on glucose production and utilization in man. J Clin Invest (1983) 4.00
ON THE HORMONAL REGULATION OF CARBOHYDRATE METABOLISM; STUDIES WITH C14 GLUCOSE. Recent Prog Horm Res (1963) 2.26
Overnight lowering of free fatty acids with Acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects. Diabetes (1999) 2.14
The effect of nicotinic acid on the plasma free fatty acid; demonstration of a metabolic type of sympathicolysis. Acta Med Scand (1962) 1.66
Effect of a sustained reduction in plasma free fatty acid concentration on intramuscular long-chain fatty Acyl-CoAs and insulin action in type 2 diabetic patients. Diabetes (2005) 1.57
Effects of growth hormone on insulin action in man. Mechanisms of insulin resistance, impaired suppression of glucose production, and impaired stimulation of glucose utilization. Diabetes (1982) 1.39
EFFECT OF HUMAN GROWTH HORMONE ON MUSCLE AND ADIPOSE TISSUE METABOLISM IN THE FOREARM OF MAN. J Clin Invest (1965) 1.38
Regulation and function of insulin-like growth factor-binding protein-1. Proc Soc Exp Biol Med (1993) 1.36
Insulin resistance in type 1 diabetes. Diabetes Metab Res Rev (2002) 1.30
Modeling error and apparent isotope discrimination confound estimation of endogenous glucose production during euglycemic glucose clamps. Diabetes (1988) 1.28
Somatogenic receptors of rat liver: regulation by insulin. Endocrinology (1980) 1.23
Effects on insulin secretion and insulin action of a 48-h reduction of plasma free fatty acids with acipimox in nondiabetic subjects genetically predisposed to type 2 diabetes. Am J Physiol Endocrinol Metab (2007) 1.22
The effect of growth hormone on glucose metabolism and insulin secretion in man. J Clin Endocrinol Metab (1982) 1.21
Influence of the crosstalk between growth hormone and insulin signalling on the modulation of insulin sensitivity. Growth Horm IGF Res (2005) 1.18
Alterations in insulin binding induced by changes in vivo in the levels of glucocorticoids and growth hormone. Endocrinology (1978) 1.18
Effects of a growth hormone pulse on total and forearm substrate fluxes in humans. Am J Physiol (1990) 1.15
Comparison of peripheral and portal (via the umbilical vein) routes of insulin infusion in IDDM patients. Diabetes (1992) 1.07
Growth hormone-induced insulin resistance is associated with increased intramyocellular triglyceride content but unaltered VLDL-triglyceride kinetics. Am J Physiol Endocrinol Metab (2006) 1.07
Pharmacological antilipolysis restores insulin sensitivity during growth hormone exposure. Diabetes (2001) 1.05
The metabolic role of growth hormone in humans with particular reference to fasting. Growth Horm IGF Res (2005) 1.04
Effects of growth hormone on insulin sensitivity and forearm metabolism in normal man. Diabetologia (1989) 1.03
Insulin-like growth factor I has a direct effect on glucose and protein metabolism, but no effect on lipid metabolism in type 1 diabetes. J Clin Endocrinol Metab (2004) 1.03
Paradoxical changes in muscle gene expression in insulin-resistant subjects after sustained reduction in plasma free fatty acid concentration. Diabetes (2007) 1.02
Insulin regulates insulin-like growth factor I mRNA in rat hepatocytes. Am J Physiol (1991) 1.00
Dose-response effects of free fatty acids on glucose and lipid metabolism during somatostatin blockade of growth hormone and insulin in humans. J Clin Endocrinol Metab (2007) 0.99
Growth hormone signaling in vivo in human muscle and adipose tissue: impact of insulin, substrate background, and growth hormone receptor blockade. J Clin Endocrinol Metab (2008) 0.97
The lowering of hepatic fatty acid uptake improves liver function and insulin sensitivity without affecting hepatic fat content in humans. Am J Physiol Endocrinol Metab (2008) 0.95
Increased overnight growth hormone concentrations in diabetic compared with normal adolescents. J Clin Endocrinol Metab (1990) 0.94
Effect of nicotinic acid administration on hepatic very low density lipoprotein-triglyceride production. Am J Physiol Endocrinol Metab (2001) 0.92
Pronounced blood glucose-lowering effect of the antilipolytic drug acipimox in noninsulin-dependent diabetes mellitus patients during a 3-day intensified treatment period. J Clin Endocrinol Metab (1994) 0.91
Metabolic consequences of sustained suppression of free fatty acids by acipimox in patients with NIDDM. Diabetes (1993) 0.90
Inhibition of lipolysis during acute GH exposure increases insulin sensitivity in previously untreated GH-deficient adults. Eur J Endocrinol (2003) 0.88
Elevated leptin levels are associated with excess gains in fat mass in girls, but not boys, with type 1 diabetes: longitudinal study during adolescence. J Clin Endocrinol Metab (2001) 0.87
The effects of a specific growth hormone antagonist on overnight insulin requirements and insulin sensitivity in young adults with Type 1 diabetes mellitus. Diabetologia (2003) 0.87
Modulation of basal glucose metabolism and insulin sensitivity by growth hormone and free fatty acids during short-term fasting. Eur J Endocrinol (2004) 0.84
The nicotinic acid analogue acipimox increases plasma leptin and decreases free fatty acids in type 2 diabetic patients. Eur J Endocrinol (2000) 0.84
The dawn phenomenon is related to overnight growth hormone release in adolescent diabetics. Clin Endocrinol (Oxf) (1990) 0.82
Hepatic glucose output in humans measured with labeled glucose to reduce negative errors. Am J Physiol (1989) 0.80
Influence of growth hormone on glucose-glucose 6-phosphate cycle and insulin action in normal humans. Am J Physiol (1992) 0.80
Failure of current insulin regimes to meet the overnight requirements of adolescents with insulin-dependent diabetes. Diabetes Res (1990) 0.79
Biphasic nature of blood glucose and free fatty acid changes following intravenous nicotinic acid in man. J Clin Endocrinol Metab (1967) 0.78
Natural course of growth hormone hypersecretion in insulin-dependent diabetes mellitus. Med Hypotheses (1996) 0.78
Mediation of the hepatic effects of growth hormone by its lipolytic activity. J Clin Endocrinol Metab (1999) 0.78
The frequency and amplitude of growth hormone secretory episodes as determined by deconvolution analysis are increased in adolescents with insulin dependent diabetes mellitus and are unaffected by short-term euglycaemia. Clin Endocrinol (Oxf) (1993) 0.77
Effects of a physiological growth hormone pulse on substrate metabolism in insulin-dependent (type 1) diabetic subjects. J Clin Endocrinol Metab (1992) 0.77
Effect of recombinant human growth hormone treatment on insulin-like growth factor (IGF-I) levels in insulin-dependent diabetic patients. Acta Diabetol (1995) 0.76
Impaired somatomedin generation test in children with insulin-dependent diabetes mellitus. Diabetes (1985) 0.76
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet (2007) 19.04
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet (2007) 12.62
A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. Nat Genet (2006) 8.65
Manual closed-loop insulin delivery in children and adolescents with type 1 diabetes: a phase 2 randomised crossover trial. Lancet (2010) 6.50
Summary and recommendations of the Fifth International Workshop-Conference on Gestational Diabetes Mellitus. Diabetes Care (2007) 6.38
Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus. Diabetes (2004) 4.81
Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms. Am J Hum Genet (2005) 4.36
A family with severe insulin resistance and diabetes due to a mutation in AKT2. Science (2004) 3.54
Early insulin therapy in very-low-birth-weight infants. N Engl J Med (2008) 3.51
Overnight closed loop insulin delivery (artificial pancreas) in adults with type 1 diabetes: crossover randomised controlled studies. BMJ (2011) 3.36
Insulin, insulin-like growth factor-I (IGF-I), IGF binding proteins, their biologic interactions, and colorectal cancer. J Natl Cancer Inst (2002) 3.32
Hypomethylation of multiple imprinted loci in individuals with transient neonatal diabetes is associated with mutations in ZFP57. Nat Genet (2008) 3.06
Effectiveness of an early supplementation scheme of high-dose vitamin A versus standard WHO protocol in Gambian mothers and infants: a randomised controlled trial. Lancet (2007) 3.01
Poor prognosis of young adults with type 1 diabetes: a longitudinal study. Diabetes Care (2003) 2.75
Overnight closed-loop insulin delivery in young people with type 1 diabetes: a free-living, randomized clinical trial. Diabetes Care (2014) 2.53
Prevalence and determinants of hyperglycemia in very low birth weight infants: cohort analyses of the NIRTURE study. J Pediatr (2010) 2.50
Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma. Diabetes (2003) 2.28
Risk of microalbuminuria and progression to macroalbuminuria in a cohort with childhood onset type 1 diabetes: prospective observational study. BMJ (2008) 2.25
Size at birth and early childhood growth in relation to maternal smoking, parity and infant breast-feeding: longitudinal birth cohort study and analysis. Pediatr Res (2002) 2.22
Association of weight gain in infancy and early childhood with metabolic risk in young adults. J Clin Endocrinol Metab (2006) 2.15
Circulating concentrations of insulin-like growth factor-I and development of glucose intolerance: a prospective observational study. Lancet (2002) 2.12
The prevalence of stunting, overweight and obesity, and metabolic disease risk in rural South African children. BMC Public Health (2010) 2.08
Childhood obesity and the timing of puberty. Trends Endocrinol Metab (2009) 2.00
Upward weight percentile crossing in infancy and early childhood independently predicts fat mass in young adults: the Stockholm Weight Development Study (SWEDES). Am J Clin Nutr (2006) 1.99
Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth. PLoS Med (2010) 1.88
Early development of adiposity and insulin resistance after catch-up weight gain in small-for-gestational-age children. J Clin Endocrinol Metab (2006) 1.87
Closed-loop basal insulin delivery over 36 hours in adolescents with type 1 diabetes: randomized clinical trial. Diabetes Care (2012) 1.84
Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes. Diabetes (2011) 1.78
Downregulation of adipose tissue fatty acid trafficking in obesity: a driver for ectopic fat deposition? Diabetes (2010) 1.76
European Society for Paediatric Endocrinology/Lawson Wilkins Pediatric Endocrine Society consensus statement on diabetic ketoacidosis in children and adolescents. Pediatrics (2004) 1.71
Insulin sensitivity and secretion are related to catch-up growth in small-for-gestational-age infants at age 1 year: results from a prospective cohort. J Clin Endocrinol Metab (2003) 1.70
Low IGF-I and elevated testosterone during puberty in subjects with type 1 diabetes developing microalbuminuria in comparison to normoalbuminuric control subjects: the Oxford Regional Prospective Study. Diabetes Care (2003) 1.68
Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes. Diabetes (2007) 1.68
The relationship of disordered eating habits and attitudes to clinical outcomes in young adult females with type 1 diabetes. Diabetes Care (2005) 1.64
Overnight closed-loop insulin delivery with model predictive control: assessment of hypoglycemia and hyperglycemia risk using simulation studies. J Diabetes Sci Technol (2009) 1.63
Closed-loop insulin delivery during pregnancy complicated by type 1 diabetes. Diabetes Care (2011) 1.57
Safety and efficacy of 24-h closed-loop insulin delivery in well-controlled pregnant women with type 1 diabetes: a randomized crossover case series. Diabetes Care (2011) 1.57
Regulation of human metabolism by hypoxia-inducible factor. Proc Natl Acad Sci U S A (2010) 1.56
Conscious level in children with diabetic ketoacidosis is related to severity of acidosis and not to blood glucose concentration. Pediatr Diabetes (2006) 1.52
Effect of oxandrolone and timing of pubertal induction on final height in Turner's syndrome: randomised, double blind, placebo controlled trial. BMJ (2011) 1.50
The potential impact of the fetal genotype on maternal blood pressure during pregnancy. J Hypertens (2014) 1.49
Infancy weight gain predicts childhood body fat and age at menarche in girls. J Clin Endocrinol Metab (2009) 1.47
Simulation environment to evaluate closed-loop insulin delivery systems in type 1 diabetes. J Diabetes Sci Technol (2010) 1.47
Parental attitudes towards overnight closed-loop glucose control in children with type 1 diabetes. Diabetes Technol Ther (2010) 1.46
The association between the FTO gene and fat mass in humans develops by the postnatal age of two weeks. J Clin Endocrinol Metab (2008) 1.45
Anogenital distance from birth to 2 years: a population study. Environ Health Perspect (2009) 1.44
Hypoglycemia prevalence in prepubertal children with type 1 diabetes on standard insulin regimen: use of continuous glucose monitoring system. Diabetes Care (2003) 1.43
Dietary energy intake at the age of 4 months predicts postnatal weight gain and childhood body mass index. Pediatrics (2006) 1.43
The relationship between microalbuminuria and glomerular filtration rate in young type 1 diabetic subjects: The Oxford Regional Prospective Study. Kidney Int (2005) 1.40
Evaluation of a portable ambulatory prototype for automated overnight closed-loop insulin delivery in young people with type 1 diabetes. Pediatr Diabetes (2012) 1.40
Paradoxical elevation of high-molecular weight adiponectin in acquired extreme insulin resistance due to insulin receptor antibodies. Diabetes (2007) 1.35
Birth weight, infant growth and insulin resistance. Eur J Endocrinol (2004) 1.34
Insulin-like growth factor I concentrations in infancy predict differential gains in body length and adiposity: the Cambridge Baby Growth Study. Am J Clin Nutr (2009) 1.33
Fasted to fed trafficking of Fatty acids in human adipose tissue reveals a novel regulatory step for enhanced fat storage. J Clin Endocrinol Metab (2009) 1.28
Randomized cross-over trial of insulin glargine plus lispro or NPH insulin plus regular human insulin in adolescents with type 1 diabetes on intensive insulin regimens. Diabetes Care (2003) 1.27
Lessons from large population studies on timing and tempo of puberty (secular trends and relation to body size): the European trend. Mol Cell Endocrinol (2006) 1.25
Earlier mother's age at menarche predicts rapid infancy growth and childhood obesity. PLoS Med (2007) 1.22
ISPAD Clinical Practice Consensus Guidelines 2014. Assessment and monitoring of glycemic control in children and adolescents with diabetes. Pediatr Diabetes (2014) 1.19
Evaluating the accuracy and large inaccuracy of two continuous glucose monitoring systems. Diabetes Technol Ther (2012) 1.16
Nutritional status and HIV in rural South African children. BMC Pediatr (2011) 1.15
Common polymorphism in H19 associated with birthweight and cord blood IGF-II levels in humans. BMC Genet (2005) 1.14
Secretion of adipokines by human adipose tissue in vivo: partitioning between capillary and lymphatic transport. Am J Physiol Endocrinol Metab (2011) 1.14
Pregnancy insulin, glucose, and BMI contribute to birth outcomes in nondiabetic mothers. Diabetes Care (2008) 1.12
Automated overnight closed-loop glucose control in young children with type 1 diabetes. Diabetes Technol Ther (2011) 1.11
Glucose and lipid metabolism in small for gestational age infants at 48 hours of age. Pediatrics (2003) 1.11
Fat distribution in non-obese girls with and without precocious pubarche: central adiposity related to insulinaemia and androgenaemia from prepuberty to postmenarche. Clin Endocrinol (Oxf) (2003) 1.11
DNA methylation profiling at imprinted loci after periconceptional micronutrient supplementation in humans: results of a pilot randomized controlled trial. FASEB J (2012) 1.11
ISPAD Clinical Practice Consensus Guidelines 2014. Nutritional management in children and adolescents with diabetes. Pediatr Diabetes (2014) 1.11
Metformin treatment to prevent early puberty in girls with precocious pubarche. J Clin Endocrinol Metab (2006) 1.10
Metabolic signatures of human adipose tissue hypoxia in obesity. Diabetes (2012) 1.10
Factors controlling testis descent. Eur J Endocrinol (2008) 1.10
Meta-analysis of overnight closed-loop randomized studies in children and adults with type 1 diabetes: the Cambridge cohort. J Diabetes Sci Technol (2011) 1.09
Assessing the validity of the association between the SUMO4 M55V variant and risk of type 1 diabetes. Nat Genet (2005) 1.09
Closed-loop insulin delivery for treatment of type 1 diabetes. BMC Med (2011) 1.08
Prevalence of abnormal lipid profiles and the relationship with the development of microalbuminuria in adolescents with type 1 diabetes. Diabetes Care (2009) 1.08
Upper and lower body adipose tissue function: a direct comparison of fat mobilization in humans. Obes Res (2004) 1.07
The impact of abnormalities in IGF and inflammatory systems on the metabolic syndrome. Diabetes Care (2004) 1.07
Metformin therapy during puberty delays menarche, prolongs pubertal growth, and augments adult height: a randomized study in low-birth-weight girls with early-normal onset of puberty. J Clin Endocrinol Metab (2006) 1.06
Does the fetal genotype affect maternal physiology during pregnancy? Trends Mol Med (2007) 1.05
Femoral adipose tissue may accumulate the fat that has been recycled as VLDL and nonesterified fatty acids. Diabetes (2010) 1.04