Published in Mol Cell Biol on July 20, 2009
Uridine insertion/deletion editing in trypanosomes: a playground for RNA-guided information transfer. Wiley Interdiscip Rev RNA (2011) 1.29
TbRGG2 facilitates kinetoplastid RNA editing initiation and progression past intrinsic pause sites. RNA (2010) 1.11
Architecture of the trypanosome RNA editing accessory complex, MRB1. Nucleic Acids Res (2012) 1.10
A protein-protein interaction map of trypanosome ~20S editosomes. J Biol Chem (2009) 1.08
Endonuclease associations with three distinct editosomes in Trypanosoma brucei. J Biol Chem (2011) 1.07
MRB3010 is a core component of the MRB1 complex that facilitates an early step of the kinetoplastid RNA editing process. RNA (2011) 1.01
Functional characterization of two paralogs that are novel RNA binding proteins influencing mitochondrial transcripts of Trypanosoma brucei. RNA (2012) 0.97
The zinc-fingers of KREPA3 are essential for the complete editing of mitochondrial mRNAs in Trypanosoma brucei. PLoS One (2010) 0.89
Multifunctional G-rich and RRM-containing domains of TbRGG2 perform separate yet essential functions in trypanosome RNA editing. Eukaryot Cell (2012) 0.88
Editosome accessory factors KREPB9 and KREPB10 in Trypanosoma brucei. Eukaryot Cell (2012) 0.85
OB-fold domain of KREPA4 mediates high-affinity interaction with guide RNA and possesses annealing activity. RNA (2010) 0.85
U-Insertion/Deletion mRNA-Editing Holoenzyme: Definition in Sight. Trends Parasitol (2015) 0.84
A core MRB1 complex component is indispensable for RNA editing in insect and human infective stages of Trypanosoma brucei. PLoS One (2013) 0.84
A trypanosomal pentatricopeptide repeat protein stabilizes the mitochondrial mRNAs of cytochrome oxidase subunits 1 and 2. Eukaryot Cell (2011) 0.82
Inhibitors of RNA editing as potential chemotherapeutics against trypanosomatid pathogens. Int J Parasitol Drugs Drug Resist (2011) 0.81
Gene Loss and Error-Prone RNA Editing in the Mitochondrion of Perkinsela, an Endosymbiotic Kinetoplastid. MBio (2015) 0.81
An arginine-glycine-rich RNA binding protein impacts the abundance of specific mRNAs in the mitochondria of Trypanosoma brucei. Eukaryot Cell (2014) 0.78
Dynamics of mitochondrial RNA-binding protein complex in Trypanosoma brucei and its petite mutant under optimized immobilization conditions. Eukaryot Cell (2014) 0.77
The oligonucleotide binding (OB)-fold domain of KREPA4 is essential for stable incorporation into editosomes. PLoS One (2012) 0.76
A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei. Mol Biochem Parasitol (1999) 11.77
Complex management: RNA editing in trypanosomes. Trends Biochem Sci (2005) 3.69
An RNA ligase essential for RNA editing and survival of the bloodstream form of Trypanosoma brucei. Science (2001) 3.52
Arginine methylation facilitates the nuclear export of hnRNP proteins. Genes Dev (1998) 2.74
Targeting of a tetracycline-inducible expression system to the transcriptionally silent minichromosomes of Trypanosoma brucei. Mol Biochem Parasitol (2002) 2.74
Trypanosoma brucei gBP21. An arginine-rich mitochondrial protein that binds to guide RNA with high affinity. J Biol Chem (1997) 2.17
Mitochondrial proteins and complexes in Leishmania and Trypanosoma involved in U-insertion/deletion RNA editing. RNA (2004) 2.06
Unexplained complexity of the mitochondrial genome and transcriptome in kinetoplastid flagellates. Curr Genet (2005) 2.01
Protein arginine methylation: Cellular functions and methods of analysis. Biochim Biophys Acta (2006) 1.96
An essential RNase III insertion editing endonuclease in Trypanosoma brucei. Proc Natl Acad Sci U S A (2005) 1.96
Separate insertion and deletion subcomplexes of the Trypanosoma brucei RNA editing complex. Mol Cell (2003) 1.94
RNA editing in Trypanosoma brucei requires three different editosomes. Mol Cell Biol (2007) 1.87
Compositionally and functionally distinct editosomes in Trypanosoma brucei. RNA (2006) 1.86
Uridine insertion/deletion RNA editing in trypanosome mitochondria: a complex business. RNA (2003) 1.85
Symmetrical dimethylarginine methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing. J Cell Biol (2002) 1.83
Trypanosoma brucei RBP16 is a mitochondrial Y-box family protein with guide RNA binding activity. J Biol Chem (1999) 1.77
The F1-ATP synthase complex in bloodstream stage trypanosomes has an unusual and essential function. EMBO J (2005) 1.75
Guide RNA-binding complex from mitochondria of trypanosomatids. Mol Cell (2008) 1.75
Annealing of RNA editing substrates facilitated by guide RNA-binding protein gBP21. EMBO J (2001) 1.73
Crystal structures of T. brucei MRP1/MRP2 guide-RNA binding complex reveal RNA matchmaking mechanism. Cell (2006) 1.67
Association of guide RNA binding protein gBP21 with active RNA editing complexes in Trypanosoma brucei. Mol Cell Biol (1998) 1.66
TbMP81 is required for RNA editing in Trypanosoma brucei. EMBO J (2002) 1.65
Extensive editing of both processed and preprocessed maxicircle CR6 transcripts in Trypanosoma brucei. J Biol Chem (1992) 1.64
3' adenylation determines mRNA abundance and monitors completion of RNA editing in T. brucei mitochondria. EMBO J (2008) 1.63
RNA interference analyses suggest a transcript-specific regulatory role for mitochondrial RNA-binding proteins MRP1 and MRP2 in RNA editing and other RNA processing in Trypanosoma brucei. J Biol Chem (2004) 1.58
RBP16 is a multifunctional gene regulatory protein involved in editing and stabilization of specific mitochondrial mRNAs in Trypanosoma brucei. RNA (2003) 1.53
Adaptations of Trypanosoma brucei to gradual loss of kinetoplast DNA: Trypanosoma equiperdum and Trypanosoma evansi are petite mutants of T. brucei. Proc Natl Acad Sci U S A (2008) 1.51
TbRGG1, an essential protein involved in kinetoplastid RNA metabolism that is associated with a novel multiprotein complex. RNA (2008) 1.47
The involvement of gRNA-binding protein gBP21 in RNA editing-an in vitro and in vivo analysis. Nucleic Acids Res (1999) 1.45
Mitochondrial mRNA 3' cleavage/polyadenylation and RNA editing in Trypanosoma brucei are independent events. Mol Biochem Parasitol (1997) 1.44
ATP synthase is responsible for maintaining mitochondrial membrane potential in bloodstream form Trypanosoma brucei. Eukaryot Cell (2006) 1.39
TbRGG2, an essential RNA editing accessory factor in two Trypanosoma brucei life cycle stages. J Biol Chem (2008) 1.33
Opposing effects of polyadenylation on the stability of edited and unedited mitochondrial RNAs in Trypanosoma brucei. Mol Cell Biol (2005) 1.32
An aurora kinase homologue is involved in regulating both mitosis and cytokinesis in Trypanosoma brucei. J Biol Chem (2006) 1.31
RNA-binding properties of the mitochondrial Y-box protein RBP16. Nucleic Acids Res (2000) 1.20
Mapping contacts between gRNA and mRNA in trypanosome RNA editing. Nucleic Acids Res (1999) 1.16
The major messenger ribonucleoprotein particle protein p50 (YB-1) promotes nucleic acid strand annealing. J Biol Chem (2001) 1.16
Structure and function of the native and recombinant mitochondrial MRP1/MRP2 complex from Trypanosoma brucei. Int J Parasitol (2008) 1.13
Positive and negative effects of the major mammalian messenger ribonucleoprotein p50 on binding of 40 S ribosomal subunits to the initiation codon of beta-globin mRNA. J Biol Chem (2002) 1.11
Mechanism of the gBP21-mediated RNA/RNA annealing reaction: matchmaking and charge reduction. Nucleic Acids Res (2002) 1.09
A type III protein arginine methyltransferase from the protozoan parasite Trypanosoma brucei. J Biol Chem (2009) 1.06
gRNA/pre-mRNA annealing and RNA chaperone activities of RBP16. RNA (2008) 1.06
RBP16 stimulates trypanosome RNA editing in vitro at an early step in the editing reaction. RNA (2006) 1.06
Arginine methylation regulates mitochondrial gene expression in Trypanosoma brucei through multiple effector proteins. RNA (2006) 1.05
Isolation and compositional analysis of trypanosomatid editosomes. Methods Enzymol (2007) 1.03
Methylation of Xenopus CIRP2 regulates its arginine- and glycine-rich region-mediated nucleocytoplasmic distribution. Nucleic Acids Res (2002) 1.02
In vitro and in vivo analysis of the major type I protein arginine methyltransferase from Trypanosoma brucei. Mol Biochem Parasitol (2005) 1.00
Differential effects of arginine methylation on RBP16 mRNA binding, guide RNA (gRNA) binding, and gRNA-containing ribonucleoprotein complex (gRNP) formation. J Biol Chem (2007) 0.97
The effect of down-regulation of mitochondrial RNA-binding proteins MRP1 and MRP2 on respiratory complexes in procyclic Trypanosoma brucei. Mol Biochem Parasitol (2006) 0.93
Evolutionarily divergent type II protein arginine methyltransferase in Trypanosoma brucei. Eukaryot Cell (2007) 0.92
Targeted depletion of a mitochondrial nucleotidyltransferase suggests the presence of multiple enzymes that polymerize mRNA 3' tails in Trypanosoma brucei mitochondria. Mol Biochem Parasitol (2007) 0.90
The ins and outs of editing RNA in kinetoplastids. Parasitol Today (1995) 0.86
Trypanosoma brucei: functions of RBP16 cold shock and RGG domains in macromolecular interactions. Exp Parasitol (2003) 0.85
RBP16 is a multifunctional gene regulatory protein involved in editing and stabilization of specific mitochondrial mRNAs in Trypanosoma brucei. RNA (2003) 1.53
Pentatricopeptide repeat proteins in Trypanosoma brucei function in mitochondrial ribosomes. Mol Cell Biol (2007) 1.44
TbRGG2, an essential RNA editing accessory factor in two Trypanosoma brucei life cycle stages. J Biol Chem (2008) 1.33
Opposing effects of polyadenylation on the stability of edited and unedited mitochondrial RNAs in Trypanosoma brucei. Mol Cell Biol (2005) 1.32
Amino acid substitutions in yeast TFIIF confer upstream shifts in transcription initiation and altered interaction with RNA polymerase II. Mol Cell Biol (2004) 1.26
Dual core processing: MRB1 is an emerging kinetoplast RNA editing complex. Trends Parasitol (2013) 1.17
Nuclear Exclusion of the HIV-1 host defense factor APOBEC3G requires a novel cytoplasmic retention signal and is not dependent on RNA binding. J Biol Chem (2007) 1.13
Functions of Saccharomyces cerevisiae TFIIF during transcription start site utilization. Mol Cell Biol (2008) 1.12
TbRGG2 facilitates kinetoplastid RNA editing initiation and progression past intrinsic pause sites. RNA (2010) 1.11
Polyadenylation regulates the stability of Trypanosoma brucei mitochondrial RNAs. J Biol Chem (2003) 1.11
Architecture of the trypanosome RNA editing accessory complex, MRB1. Nucleic Acids Res (2012) 1.10
Yeast RNA polymerase II lacking the Rpb9 subunit is impaired for interaction with transcription factor IIF. J Biol Chem (2003) 1.09
UTP-dependent turnover of Trypanosoma brucei mitochondrial mRNA requires UTP polymerization and involves the RET1 TUTase. RNA (2005) 1.06
A type III protein arginine methyltransferase from the protozoan parasite Trypanosoma brucei. J Biol Chem (2009) 1.06
gRNA/pre-mRNA annealing and RNA chaperone activities of RBP16. RNA (2008) 1.06
RBP16 stimulates trypanosome RNA editing in vitro at an early step in the editing reaction. RNA (2006) 1.06
Arginine methylation regulates mitochondrial gene expression in Trypanosoma brucei through multiple effector proteins. RNA (2006) 1.05
MRB3010 is a core component of the MRB1 complex that facilitates an early step of the kinetoplastid RNA editing process. RNA (2011) 1.01
In vitro and in vivo analysis of the major type I protein arginine methyltransferase from Trypanosoma brucei. Mol Biochem Parasitol (2005) 1.00
Proteomic analysis reveals diverse classes of arginine methylproteins in mitochondria of trypanosomes. Mol Cell Proteomics (2012) 0.98
Functional characterization of two paralogs that are novel RNA binding proteins influencing mitochondrial transcripts of Trypanosoma brucei. RNA (2012) 0.97
Differential effects of arginine methylation on RBP16 mRNA binding, guide RNA (gRNA) binding, and gRNA-containing ribonucleoprotein complex (gRNP) formation. J Biol Chem (2007) 0.97
Protein arginine methylation in parasitic protozoa. Eukaryot Cell (2011) 0.97
Guide RNA biogenesis involves a novel RNase III family endoribonuclease in Trypanosoma brucei. RNA (2011) 0.96
Isolation of RNA binding proteins involved in insertion/deletion editing. Methods Enzymol (2007) 0.96
TbPRMT6 is a type I protein arginine methyltransferase that contributes to cytokinesis in Trypanosoma brucei. Eukaryot Cell (2010) 0.94
Roles for TbDSS-1 in RNA surveillance and decay of maturation by-products from the 12S rRNA locus. Nucleic Acids Res (2007) 0.92
Additive and transcript-specific effects of KPAP1 and TbRND activities on 3' non-encoded tail characteristics and mRNA stability in Trypanosoma brucei. PLoS One (2012) 0.92
Evolutionarily divergent type II protein arginine methyltransferase in Trypanosoma brucei. Eukaryot Cell (2007) 0.92
Global proteomic analysis in trypanosomes reveals unique proteins and conserved cellular processes impacted by arginine methylation. J Proteomics (2013) 0.91
Targeted depletion of a mitochondrial nucleotidyltransferase suggests the presence of multiple enzymes that polymerize mRNA 3' tails in Trypanosoma brucei mitochondria. Mol Biochem Parasitol (2007) 0.90
Multifunctional G-rich and RRM-containing domains of TbRGG2 perform separate yet essential functions in trypanosome RNA editing. Eukaryot Cell (2012) 0.88
TbDSS-1, an essential Trypanosoma brucei exoribonuclease homolog that has pleiotropic effects on mitochondrial RNA metabolism. Eukaryot Cell (2004) 0.88
A novel member of the RNase D exoribonuclease family functions in mitochondrial guide RNA metabolism in Trypanosoma brucei. J Biol Chem (2011) 0.86
Genetic interactions between TFIIF and TFIIS. Genetics (2006) 0.85
Trypanosoma brucei: functions of RBP16 cold shock and RGG domains in macromolecular interactions. Exp Parasitol (2003) 0.85
Structure of the Trypanosoma brucei p22 protein, a cytochrome oxidase subunit II-specific RNA-editing accessory factor. J Biol Chem (2010) 0.85
A core MRB1 complex component is indispensable for RNA editing in insect and human infective stages of Trypanosoma brucei. PLoS One (2013) 0.84
Evidence for a degradosome-like complex in the mitochondria of Trypanosoma brucei. FEBS Lett (2009) 0.83
Biphasic decay of guide RNAs in Trypanosoma brucei. Mol Biochem Parasitol (2005) 0.83
Functional interplay between protein arginine methyltransferases in Trypanosoma brucei. Microbiologyopen (2014) 0.82
Generation of polyclonal antiserum for the detection of methylarginine proteins. J Immunol Methods (2007) 0.81
Ribosome biogenesis requires a highly diverged XRN family 5'->3' exoribonuclease for rRNA processing in Trypanosoma brucei. RNA (2013) 0.78
Marked for translation: long A/U tails as an interface between completion of RNA editing and ribosome recruitment. Mol Cell (2011) 0.75