Lynne E Maquat

Author PubWeight™ 91.79‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3' UTRs via Alu elements. Nature 2011 5.42
2 Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function. Genes Dev 2007 4.97
3 Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities. Mol Cell 2003 4.17
4 Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay. Cell 2005 4.02
5 Mechanistic links between nonsense-mediated mRNA decay and pre-mRNA splicing in mammalian cells. Curr Opin Cell Biol 2005 3.99
6 Regulation of cytoplasmic mRNA decay. Nat Rev Genet 2012 3.30
7 Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay. Cell 2008 3.26
8 Quantitative microarray profiling provides evidence against widespread coupling of alternative splicing with nonsense-mediated mRNA decay to control gene expression. Genes Dev 2006 3.18
9 The multiple lives of NMD factors: balancing roles in gene and genome regulation. Nat Rev Genet 2008 3.00
10 The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling. EMBO J 2002 2.76
11 Organizing principles of mammalian nonsense-mediated mRNA decay. Annu Rev Genet 2013 2.55
12 Applying nonsense-mediated mRNA decay research to the clinic: progress and challenges. Trends Mol Med 2006 2.39
13 Regulation of multiple core spliceosomal proteins by alternative splicing-coupled nonsense-mediated mRNA decay. Mol Cell Biol 2008 2.25
14 Staufen1 regulates diverse classes of mammalian transcripts. EMBO J 2007 2.18
15 The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells. Mol Cell 2004 2.09
16 UPF1 association with the cap-binding protein, CBP80, promotes nonsense-mediated mRNA decay at two distinct steps. Mol Cell 2010 2.04
17 CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells. Nat Struct Mol Biol 2005 2.00
18 SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs. Genes Dev 2008 1.97
19 A yeast model of FUS/TLS-dependent cytotoxicity. PLoS Biol 2011 1.95
20 The pioneer translation initiation complex is functionally distinct from but structurally overlaps with the steady-state translation initiation complex. Genes Dev 2004 1.93
21 Characterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1. RNA 2003 1.93
22 eIF4G is required for the pioneer round of translation in mammalian cells. Nat Struct Mol Biol 2004 1.54
23 Nonsense-mediated mRNA decay (NMD) in animal embryogenesis: to die or not to die, that is the question. Curr Opin Genet Dev 2011 1.52
24 Evidence that poly(A) binding protein C1 binds nuclear pre-mRNA poly(A) tails. Mol Cell Biol 2006 1.50
25 Beta -Globin mRNA decay in erythroid cells: UG site-preferred endonucleolytic cleavage that is augmented by a premature termination codon. Proc Natl Acad Sci U S A 2002 1.33
26 STAU1 binding 3' UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdown. Genes Dev 2013 1.32
27 Re-capping the message. Trends Biochem Sci 2009 1.28
28 Failsafe nonsense-mediated mRNA decay does not detectably target eIF4E-bound mRNA. Nat Struct Mol Biol 2007 1.26
29 Staufen-mediated mRNA decay. Wiley Interdiscip Rev RNA 2013 1.26
30 Efficiency of the pioneer round of translation affects the cellular site of nonsense-mediated mRNA decay. Mol Cell 2008 1.22
31 Remodeling of the pioneer translation initiation complex involves translation and the karyopherin importin beta. Genes Dev 2009 1.22
32 Control of myogenesis by rodent SINE-containing lncRNAs. Genes Dev 2013 1.21
33 Temporal and spatial characterization of nonsense-mediated mRNA decay. Genes Dev 2013 1.18
34 Rules that govern UPF1 binding to mRNA 3' UTRs. Proc Natl Acad Sci U S A 2013 1.13
35 Staufen2 functions in Staufen1-mediated mRNA decay by binding to itself and its paralog and promoting UPF1 helicase but not ATPase activity. Proc Natl Acad Sci U S A 2012 1.06
36 Cap-binding protein 1-mediated and eukaryotic translation initiation factor 4E-mediated pioneer rounds of translation in yeast. Proc Natl Acad Sci U S A 2005 1.05
37 mRNA-mRNA duplexes that autoelicit Staufen1-mediated mRNA decay. Nat Struct Mol Biol 2013 1.01
38 Staufen1 dimerizes through a conserved motif and a degenerate dsRNA-binding domain to promote mRNA decay. Nat Struct Mol Biol 2013 1.00
39 The dharma of nonsense-mediated mRNA decay in mammalian cells. Mol Cells 2014 0.95
40 NMD resulting from encephalomyocarditis virus IRES-directed translation initiation seems to be restricted to CBP80/20-bound mRNA. EMBO Rep 2008 0.95
41 "Alu"strious long ncRNAs and their role in shortening mRNA half-lives. Cell Cycle 2011 0.92
42 Biochemical analysis of long non-coding RNA-containing ribonucleoprotein complexes. Methods 2012 0.91
43 Chapter 9. Studying nonsense-mediated mRNA decay in mammalian cells. Methods Enzymol 2008 0.87
44 Immunopurification and analysis of protein and RNA components of mRNP in mammalian cells. Methods Mol Biol 2004 0.85
45 An enemy within: fly reconnaissance deploys an endonuclease to destroy nonsense-containing mRNA. Trends Cell Biol 2004 0.80
46 Affinity purification of long noncoding RNA-protein complexes from formaldehyde cross-linked mammalian cells. Methods Mol Biol 2015 0.78
47 New gene expression pipelines gush lncRNAs. Genome Biol 2013 0.77
48 RNA turnover in eukaryotes: nucleases, pathways and analysis of mRNA decay. Preface. Methods Enzymol 2008 0.77
49 UPF1 learns to relax and unwind. Mol Cell 2011 0.77
50 Nonsense-mediated decay: assaying for effects on selenoprotein mRNAs. Methods Enzymol 2002 0.76
51 RNA-protein interactions: insight into gene function. Methods 2002 0.76
52 Telomeric RNAs as a novel player in telomeric integrity. F1000 Biol Rep 2009 0.75
53 RNA turnover in eukaryotes: analysis of specialized and quality control RNA decay pathways. Preface. Methods Enzymol 2008 0.75
54 RNA turnover in prokaryotes, archaea and organelles. Preface. Methods Enzymol 2008 0.75