Published in Genes Dev on December 01, 1993
Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin. Mol Cell Biol (1998) 3.79
Synergistic activation of the fibroblast growth factor 4 enhancer by Sox2 and Oct-3 depends on protein-protein interactions facilitated by a specific spatial arrangement of factor binding sites. Mol Cell Biol (1997) 3.34
Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending. EMBO J (1994) 3.20
All Tcf HMG box transcription factors interact with Groucho-related co-repressors. Nucleic Acids Res (2001) 2.98
GATA-3: an unexpected regulator of cell lineage determination in skin. Genes Dev (2003) 2.97
Histone acetyltransferases regulate HIV-1 enhancer activity in vitro. Genes Dev (1997) 2.25
Regulation of cell-type-specific interleukin-2 receptor alpha-chain gene expression: potential role of physical interactions between Elf-1, HMG-I(Y), and NF-kappa B family proteins. Mol Cell Biol (1995) 2.07
Involvement of SOX proteins in lens-specific activation of crystallin genes. EMBO J (1995) 1.86
Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties. Mol Cell Biol (1996) 1.84
Nuclear endpoint of Wnt signaling: neoplastic transformation induced by transactivating lymphoid-enhancing factor 1. Proc Natl Acad Sci U S A (1999) 1.69
Mechanism of regulatory target selection by the SOX high-mobility-group domain proteins as revealed by comparison of SOX1/2/3 and SOX9. Mol Cell Biol (1999) 1.62
The Sry-related HMG box-containing gene Sox6 is expressed in the adult testis and developing nervous system of the mouse. Nucleic Acids Res (1995) 1.61
The erythroid Krüppel-like factor transactivation domain is a critical component for cell-specific inducibility of a beta-globin promoter. Mol Cell Biol (1995) 1.61
Heat shock transcription factor activates yeast metallothionein gene expression in response to heat and glucose starvation via distinct signalling pathways. Mol Cell Biol (1994) 1.60
A CREB-binding site as a target for decapentaplegic signalling during Drosophila endoderm induction. EMBO J (1997) 1.52
The human LEF-1 gene contains a promoter preferentially active in lymphocytes and encodes multiple isoforms derived from alternative splicing. Nucleic Acids Res (2000) 1.50
Nuclear localization and formation of beta-catenin-lymphoid enhancer factor 1 complexes are not sufficient for activation of gene expression. Mol Cell Biol (1999) 1.49
The notch intracellular domain can function as a coactivator for LEF-1. Mol Cell Biol (2001) 1.45
Microphthalmia-associated transcription factor interacts with LEF-1, a mediator of Wnt signaling. EMBO J (2002) 1.37
Wnt-signalling pathway in ovarian epithelial tumours: increased expression of beta-catenin and GSK3beta. Br J Cancer (2003) 1.35
In vitro integration of human immunodeficiency virus type 1 cDNA into targets containing protein-induced bends. Proc Natl Acad Sci U S A (1995) 1.32
Molecular characterization of the B-box protein-protein interaction motif of the ETS-domain transcription factor Elk-1. EMBO J (1997) 1.32
PITX2 and beta-catenin interactions regulate Lef-1 isoform expression. Mol Cell Biol (2007) 1.26
Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression. BMC Cancer (2009) 1.26
Differential importin-alpha recognition and nuclear transport by nuclear localization signals within the high-mobility-group DNA binding domains of lymphoid enhancer factor 1 and T-cell factor 1. Mol Cell Biol (1998) 1.14
Cell-context dependent TCF/LEF expression and function: alternative tales of repression, de-repression and activation potentials. Crit Rev Eukaryot Gene Expr (2011) 1.09
Cooperation among multiple transcription factors is required for access to minimal T-cell receptor alpha-enhancer chromatin in vivo. Mol Cell Biol (1998) 1.06
Sca-1 knockout impairs myocardial and cardiac progenitor cell function. Circ Res (2012) 1.06
Signal- and development-dependent alternative splicing of LEF1 in T cells is controlled by CELF2. Mol Cell Biol (2011) 1.06
The DNA sequence specificity of HMG boxes lies in the minor wing of the structure. EMBO J (1994) 1.04
Functional interactions between Dlx2 and lymphoid enhancer factor regulate Msx2. Nucleic Acids Res (2006) 1.03
E-cadherin involved in inactivation of WNT/beta-catenin signalling in urothelial carcinoma and normal urothelial cells. Br J Cancer (2003) 1.01
Activation of the immunoglobulin kappa 3' enhancer in pre-B cells correlates with the suppression of a nuclear factor binding to a sequence flanking the active core. Nucleic Acids Res (1994) 1.00
Functional analysis of DNA bending and unwinding by the high mobility group domain of LEF-1. Proc Natl Acad Sci U S A (1997) 0.99
Ku protein as a potential human T-cell leukemia virus type 1 (HTLV-1) Tax target in clastogenic chromosomal instability of mammalian cells. Retrovirology (2005) 0.98
LexA chimeras reveal the function of Drosophila Fos as a context-dependent transcriptional activator. Proc Natl Acad Sci U S A (2000) 0.97
Characterization of a transient TCF/LEF-responsive progenitor population in the embryonic mouse retina. Invest Ophthalmol Vis Sci (2008) 0.96
The DNA bend angle and binding affinity of an HMG box increased by the presence of short terminal arms. Nucleic Acids Res (1996) 0.96
Runx2 and bone morphogenic protein 2 regulate the expression of an alternative Lef1 transcript during osteoblast maturation. J Cell Physiol (2009) 0.95
Ligand-dependent and -independent transactivation by thyroid hormone receptor beta 2 is determined by the structure of the hormone response element. Mol Cell Biol (1995) 0.94
Discovery of inhibitors of aberrant gene transcription from Libraries of DNA binding molecules: inhibition of LEF-1-mediated gene transcription and oncogenic transformation. J Am Chem Soc (2009) 0.93
The HMG domain protein SSRP1/PREIIBF is involved in activation of the human embryonic beta-like globin gene. Mol Cell Biol (1998) 0.92
Context dependent transactivation domains activate the immunoglobulin mu heavy chain gene enhancer. EMBO J (1996) 0.92
The peri-kappa B site mediates human immunodeficiency virus type 2 enhancer activation in monocytes but not in T cells. J Virol (1995) 0.91
A dimer-specific function of the transcription factor NFATp. Proc Natl Acad Sci U S A (2008) 0.91
Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain. Brain Struct Funct (2012) 0.89
Looping mediated interaction between the promoter and 3' UTR regulates type II collagen expression in chondrocytes. PLoS One (2012) 0.85
A re-evaluation of two key reagents for in vivo studies of Wnt signaling. Dev Dyn (2011) 0.82
Nmp4/CIZ: road block at the intersection of PTH and load. Bone (2009) 0.82
A yeast model system for functional analysis of beta-catenin signaling. J Cell Biol (2002) 0.82
GATA elements are necessary for the activity and tissue specificity of the T-cell receptor beta-chain transcriptional enhancer. Mol Cell Biol (1994) 0.80
An enhancer LEF-1/TCF-1 site is essential for insertion site-independent transgene expression in thymus. Nucleic Acids Res (1996) 0.78
Past visits present: TCF/LEFs partner with ATFs for β-catenin-independent activity. PLoS Genet (2013) 0.77
GRG5/AES interacts with T-cell factor 4 (TCF4) and downregulates Wnt signaling in human cells and zebrafish embryos. PLoS One (2013) 0.75
Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro. Cell (1985) 11.03
A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication. Cell (1987) 10.22
A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA. Cell (1998) 10.14
Activation of the AIDS retrovirus promoter by the cellular transcription factor, Sp1. Science (1986) 8.01
Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer. Nat Genet (2001) 5.09
The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein. Genes Dev (1998) 4.38
A thymus-specific member of the HMG protein family regulates the human T cell receptor C alpha enhancer. Genes Dev (1991) 4.25
Sp1 binds to promoter sequences and activates herpes simplex virus 'immediate-early' gene transcription in vitro. Nature (1985) 3.99
Trace amines: identification of a family of mammalian G protein-coupled receptors. Proc Natl Acad Sci U S A (2001) 3.23
Diversity of LEF/TCF action in development and disease. Oncogene (2006) 2.84
Essential contact residues within SV40 large T antigen binding sites I and II identified by alkylation-interference. Cell (1984) 2.59
Two distinct nuclear transcription factors recognize loop and bulge residues of the HIV-1 TAR RNA hairpin. Genes Dev (1991) 2.49
Inhibition of axonal growth by SNAP-25 antisense oligonucleotides in vitro and in vivo. Nature (1993) 2.43
In vitro formation of short RNA polymerase II transcripts that terminate within the HIV-1 and HIV-2 promoter-proximal downstream regions. Genes Dev (1989) 2.36
Histone acetyltransferases regulate HIV-1 enhancer activity in vitro. Genes Dev (1997) 2.25
Purification of TCF-1 alpha, a T-cell-specific transcription factor that activates the T-cell receptor C alpha gene enhancer in a context-dependent manner. New Biol (1990) 2.21
In vitro activation of the HIV-1 enhancer in extracts from cells treated with a phorbol ester tumor promoter. EMBO J (1987) 2.09
NF-kappa B-mediated chromatin reconfiguration and transcriptional activation of the HIV-1 enhancer in vitro. Genes Dev (1996) 2.07
Functional selectivity of recombinant mammalian SWI/SNF subunits. Genes Dev (2000) 2.07
Activation of the HIV-1 enhancer by the LEF-1 HMG protein on nucleosome-assembled DNA in vitro. Genes Dev (1995) 2.07
Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice. J Clin Invest (1999) 2.02
Prediction of femoral fracture load using automated finite element modeling. J Biomech (1998) 1.99
GABAB receptors - the first 7TM heterodimers. Trends Pharmacol Sci (1999) 1.94
Tat-associated kinase, TAK, activity is regulated by distinct mechanisms in peripheral blood lymphocytes and promonocytic cell lines. J Virol (1998) 1.93
CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA. Mol Cell Biol (2000) 1.89
Steroid receptor-mediated inhibition of rat prolactin gene expression does not require the receptor DNA-binding domain. Cell (1988) 1.87
HIV-1 Tat: coping with negative elongation factors. Curr Opin Immunol (1999) 1.81
Trans-activation by human immunodeficiency virus Tat protein requires the C-terminal domain of RNA polymerase II. Proc Natl Acad Sci U S A (1996) 1.68
Distinct roles for P-CREB and LEF-1 in TCR alpha enhancer assembly and activation on chromatin templates in vitro. Genes Dev (1997) 1.65
The human LEF-1 gene contains a promoter preferentially active in lymphocytes and encodes multiple isoforms derived from alternative splicing. Nucleic Acids Res (2000) 1.50
Nuclear localization and formation of beta-catenin-lymphoid enhancer factor 1 complexes are not sufficient for activation of gene expression. Mol Cell Biol (1999) 1.49
The nuclear localization signal of lymphoid enhancer factor-1 is recognized by two differentially expressed Srp1-nuclear localization sequence receptor proteins. J Biol Chem (1996) 1.49
Chromatin-specific regulation of LEF-1-beta-catenin transcription activation and inhibition in vitro. Genes Dev (2001) 1.48
Identification and characterization of two G protein-coupled receptors for neuropeptide FF. J Biol Chem (2000) 1.41
Cloning of an SNF2/SWI2-related protein that binds specifically to the SPH motifs of the SV40 enhancer and to the HIV-1 promoter. J Biol Chem (1995) 1.35
Friction in airway smooth muscle: mechanism, latch, and implications in asthma. J Appl Physiol (1985) (1996) 1.34
Mutational analysis of simian virus 40 large T antigen DNA binding sites. EMBO J (1984) 1.31
Comparison of two murine models of familial hypertrophic cardiomyopathy. Circ Res (2001) 1.30
HIV-1 Tat interacts with cyclin T1 to direct the P-TEFb CTD kinase complex to TAR RNA. Cold Spring Harb Symp Quant Biol (1998) 1.29
HIV-1 TAR RNA enhances the interaction between Tat and cyclin T1. J Biol Chem (2000) 1.26
Functional properties of a cloned 5-hydroxytryptamine ionotropic receptor subunit: comparison with native mouse receptors. J Physiol (1994) 1.26
Expression of Wnt ligands and Frizzled receptors in colonic mucosa and in colon carcinoma. Mol Pathol (2002) 1.25
Home monitoring of transcutaneous oxygen tension in the early detection of hypoxaemia in infants and young children. Arch Dis Child (1991) 1.23
Cloned human and rat galanin GALR3 receptors. Pharmacology and activation of G-protein inwardly rectifying K+ channels. J Biol Chem (1998) 1.18
Differential importin-alpha recognition and nuclear transport by nuclear localization signals within the high-mobility-group DNA binding domains of lymphoid enhancer factor 1 and T-cell factor 1. Mol Cell Biol (1998) 1.14
HIV-1 core promoter lacks a simple initiator element but contains a bipartite activator at the transcription start site. J Biol Chem (1993) 1.13
Prediction of fracture location in the proximal femur using finite element models. Med Eng Phys (2001) 1.13
Expression cloning of a rat hypothalamic galanin receptor coupled to phosphoinositide turnover. J Biol Chem (1997) 1.13
Hyperkinetic borderline hypertension in Tecumseh, Michigan. J Hypertens (1991) 1.10
A neural network predicts progression for men with gleason score 3+4 versus 4+3 tumors after radical prostatectomy. Urology (2000) 1.10
Control of interneuron dendritic growth through NRG1/erbB4-mediated kalirin-7 disinhibition. Mol Psychiatry (2011) 1.09
A Wnt kinase network alters nuclear localization of TCF-1 in colon cancer. Oncogene (2009) 1.07
31P NMR saturation-transfer measurements in Saccharomyces cerevisiae: characterization of phosphate exchange reactions by iodoacetate and antimycin A inhibition. Biochemistry (1987) 1.05
Regulation of BRCA1. Nature (1995) 1.04
D2, D3, and D4 dopamine receptors couple to G protein-regulated potassium channels in Xenopus oocytes. Mol Pharmacol (1996) 0.99
Cell-specific expression of group X and group V secretory phospholipases A(2) in human lung airway epithelial cells. Am J Respir Cell Mol Biol (2000) 0.97
(2S,4R)-4-methylglutamic acid (SYM 2081): a selective, high-affinity ligand for kainate receptors. J Pharmacol Exp Ther (1997) 0.97
Role of protein kinase C in calcium sensitization during muscarinic stimulation in airway smooth muscle. Am J Physiol (1997) 0.95
Intestinal adenoma formation and MYC activation are regulated by cooperation between MYB and Wnt signaling. Cell Death Differ (2009) 0.91
Genetically engineered neural networks for predicting prostate cancer progression after radical prostatectomy. Urology (1999) 0.90
Halothane attenuates calcium sensitization in airway smooth muscle by inhibiting G-proteins. Anesthesiology (1998) 0.89
cGMP-independent mechanism of airway smooth muscle relaxation induced by S-nitrosoglutathione. Am J Physiol (1998) 0.88
Cortical neurons containing calretinin are selectively resistant to calcium overload and excitotoxicity in vitro. Neuroscience (1994) 0.88
Cloning and characterization of the human galanin GALR2 receptor. Peptides (1998) 0.87
Organization of the mouse 5-HT3 receptor gene and functional expression of two splice variants. Brain Res Mol Brain Res (1994) 0.86
Pharmacological characterization of a novel positive modulator at alpha 4 beta 3 delta-containing extrasynaptic GABA(A) receptors. Neuropharmacology (2010) 0.86
Physical mapping, cloning, and identification of genes within a 500-kb region containing BRCA1. Proc Natl Acad Sci U S A (1995) 0.85
Induction of heat shock proteins by canavanine in Tetrahymena. No change in ATP levels measured in vivo by NMR. J Biol Chem (1986) 0.85
Reversibility characteristics of glucose-induced trehalase activation associated with the breaking of dormancy in yeast ascospores. Eur J Biochem (1983) 0.85
In vivo 31P nuclear magnetic resonance saturation transfer measurements of phosphate exchange reactions in the yeast Saccharomyces cerevisiae. FEBS Lett (1985) 0.84
Calcium concentration-dependent mechanisms through which ketamine relaxes canine airway smooth muscle. Anesthesiology (1997) 0.84
Biological actions of oncogenes. Pharmacol Ther (1993) 0.83
Substituted 1,2-dihydrophthalazines: potent, selective, and noncompetitive inhibitors of the AMPA receptor. J Med Chem (1996) 0.83
Molecular modelling and site-directed mutagenesis of human GALR1 galanin receptor defines determinants of receptor subtype specificity. Protein Eng (2002) 0.83
The strain variation and virulence of granulovirus of diamondback moth (Plutella xylostella Linnaeus, Lep., Yponomeutidae) isolated in Kenya. J Invertebr Pathol (2002) 0.82
Clinical evaluation comparing AxSYM CA 15-3, IMx CA 15-3 and Truquant BRTM RIA. Tumour Biol (1998) 0.81
Effects of intravenous anesthetics on Ca2+ sensitivity in canine tracheal smooth muscle. Anesthesiology (2000) 0.81
Cross-bridge cycling kinetics, actomyosin ATPase activity and myosin heavy chain isoforms in skeletal and smooth respiratory muscles. Comp Biochem Physiol B Biochem Mol Biol (1998) 0.81
Efficacy trials with tissue-culture grown, inactivated vaccines against chlamydial abortion in sheep. Vaccine (1995) 0.81
An in situ hybridization study of the distribution of the GABA(B2) protein mRNA in the rat CNS. Brain Res Mol Brain Res (1999) 0.81
Calcium sensitization produced by G protein activation in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol (2001) 0.80
The effects of ethanol on CA(2+) sensitivity in airway smooth muscle. Anesth Analg (2001) 0.80
Protein and RNA affinity selection techniques using HIV-1 Tat. Methods Enzymol (1999) 0.79
The in vivo production of Spodoptera littoralis nuclear polyhedrosis virus. J Virol Methods (1998) 0.79
The Tecumseh Blood Pressure Study. Normative data on blood pressure self-determination. Arch Intern Med (1990) 0.79
A versatile, computer-controlled, closed-loop system for continuous infusion of muscle relaxants. Mayo Clin Proc (1993) 0.78
Relationship between force and regulatory myosin light chain phosphorylation in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol (2000) 0.78
The HIP116 SNF2/SW12-related transcription factor gene (SNF2L3) is located on human chromosome 3q25.1-q26.1. Genomics (1995) 0.78
Differential backfilling of interneuron populations based upon axon projections in a lobster abdominal ganglion. J Neurobiol (1983) 0.78
Effect of halothane on intracellular calcium oscillations in porcine tracheal smooth muscle cells. Am J Physiol (1999) 0.78
The role of free/total prostate-specific antigen ratio in the prediction of final pathologic stage for men with clinically localized prostate cancer. Urology (1996) 0.78
Hydrogen peroxide decreases Ca(2+) sensitivity in airway smooth muscle by inhibiting rMLC phosphorylation. Am J Physiol (1999) 0.78
Halothane attenuation of calcium sensitivity in airway smooth muscle. Mechanisms of action during muscarinic receptor stimulation. Anesthesiology (1997) 0.78
Postural interneurons in the abdominal nervous system of lobster. I. Organization, morphologies and motor programs for flexion, extension and inhibition. J Comp Physiol A (1986) 0.78
Use of nitric oxide-nucleophile adducts as biological sources of nitric oxide: effects on airway smooth muscle. J Pharmacol Exp Ther (1996) 0.77
Effect of phorbol esters on Ca2+ sensitivity and myosin light-chain phosphorylation in airway smooth muscle. Am J Physiol (1998) 0.77
Halothane and potassium channels in airway smooth muscle. Br J Anaesth (1996) 0.77
The role of cGMP in the relaxation to nitric oxide donors in airway smooth muscle. Eur J Pharmacol (1998) 0.77
Technical evaluation of five glucose meters with data management capabilities. Am J Clin Pathol (1999) 0.77
S-nitrosoglutathione-induced decrease in calcium sensitivity of airway smooth muscle. Am J Physiol Lung Cell Mol Physiol (2000) 0.76