Published in J Immunol on September 28, 2009
Neuroimmunological blood brain barrier opening in experimental cerebral malaria. PLoS Pathog (2012) 1.35
TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation. J Exp Med (2012) 1.24
Role of reactive oxygen and nitrogen species in the vascular responses to inflammation. Free Radic Biol Med (2011) 1.17
Production of proinflammatory cytokines and chemokines during neuroinflammation: novel roles for estrogen receptors alpha and beta. Endocrinology (2010) 1.17
LPS-induced murine systemic inflammation is driven by parenchymal cell activation and exclusively predicted by early MCP-1 plasma levels. Am J Pathol (2011) 1.04
Molecular and cellular neuroinflammatory status of mouse brain after systemic lipopolysaccharide challenge: importance of CCR2/CCL2 signaling. J Neuroinflammation (2014) 1.04
Experimental cerebral malaria pathogenesis--hemodynamics at the blood brain barrier. PLoS Pathog (2014) 0.97
Resistance of the brain to Escherichia coli K1 infection depends on MyD88 signaling and the contribution of neutrophils and monocytes. Infect Immun (2013) 0.96
CXCL1 can be regulated by IL-6 and promotes granulocyte adhesion to brain capillaries during bacterial toxin exposure and encephalomyelitis. J Neuroinflammation (2012) 0.95
Brain-reactive antibodies and disease. Annu Rev Immunol (2013) 0.94
Endotoxin-induced uveitis is primarily dependent on radiation-resistant cells and on MyD88 but not TRIF. J Leukoc Biol (2011) 0.86
Role of brain transmigrating neutrophils in depression-like behavior during systemic infection. Mol Psychiatry (2013) 0.85
Increased toll-like receptor 4 in cerebral endothelial cells contributes to the astrocyte swelling and brain edema in acute hepatic encephalopathy. J Neurochem (2013) 0.85
Glia-pinealocyte network: the paracrine modulation of melatonin synthesis by tumor necrosis factor (TNF). PLoS One (2012) 0.85
Neurotrauma and inflammation: CNS and PNS responses. Mediators Inflamm (2015) 0.84
Sphingosine kinase 1 deficiency exacerbates LPS-induced neuroinflammation. PLoS One (2012) 0.84
Real-time detection of implant-associated neutrophil responses using a formyl peptide receptor-targeting NIR nanoprobe. Int J Nanomedicine (2012) 0.84
Neutrophil responses to injury or inflammation impair peripheral gustatory function. Neuroscience (2010) 0.83
Repeated Social Defeat, Neuroinflammation, and Behavior: Monocytes Carry the Signal. Neuropsychopharmacology (2016) 0.82
Treatment with gelsolin reduces brain inflammation and apoptotic signaling in mice following thermal injury. J Neuroinflammation (2011) 0.82
Lipopolysaccharide potentiates polychlorinated biphenyl-induced disruption of the blood-brain barrier via TLR4/IRF-3 signaling. Toxicology (2012) 0.81
Imaging Plasmodium immunobiology in the liver, brain, and lung. Parasitol Int (2013) 0.81
Individual Cytokines Modulate the Neurological Symptoms of ATM Deficiency in a Region Specific Manner(1,2,3). eNeuro (2015) 0.79
Role and interactions of annexin A1 and oestrogens in the manifestation of sexual dimorphisms in cerebral and systemic inflammation. Br J Pharmacol (2013) 0.78
Toll-like receptors 4 and 9 are responsible for the maintenance of the inflammatory reaction in canine steroid-responsive meningitis-arteritis, a large animal model for neutrophilic meningitis. J Neuroinflammation (2012) 0.77
Contribution of the platelet activating factor signaling pathway to cerebral microcirculatory dysfunction during experimental sepsis by ExoU producing Pseudomonas aeruginosa. Pathog Dis (2015) 0.76
Fueling the fire in acute kidney injury: endothelial cells collect their Toll. Kidney Int (2011) 0.76
TLR4 signaling is involved in brain vascular toxicity of PCB153 bound to nanoparticles. PLoS One (2013) 0.76
Soluble CD14 in cerebrospinal fluid is associated with markers of inflammation and axonal damage in untreated HIV-infected patients: a retrospective cross-sectional study. BMC Infect Dis (2016) 0.76
Regulatory effects of the JAK3/STAT1 pathway on the release of secreted phospholipase A₂-IIA in microvascular endothelial cells of the injured brain. J Neuroinflammation (2012) 0.76
Modulatory effects of vagal stimulation on neurophysiological parameters and the cellular immune response in the rat brain during systemic inflammation. Intensive Care Med Exp (2016) 0.75
Fungal Infection in the Brain: What We Learned from Intravital Imaging. Front Immunol (2016) 0.75
Blood-Brain Barrier Deterioration and Hippocampal Gene Expression in Polymicrobial Sepsis: An Evaluation of Endothelial MyD88 and the Vagus Nerve. PLoS One (2016) 0.75
Endothelial bioreactor system ameliorates multiple organ dysfunction in septic rats. Intensive Care Med Exp (2016) 0.75
Complement component C3a plays a critical role in endothelial activation and leukocyte recruitment into the brain. J Neuroinflammation (2016) 0.75
PKR deficiency alters E. coli-induced sickness behaviors but does not exacerbate neuroimmune responses or bacterial load. J Neuroinflammation (2015) 0.75
Myocyte TLR4 enhances enteric and systemic inflammation driving late murine endotoxic ileus. Am J Physiol Gastrointest Liver Physiol (2015) 0.75
Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat Med (2007) 8.58
Neutrophil recruitment and function in health and inflammation. Nat Rev Immunol (2013) 7.10
Intravascular danger signals guide neutrophils to sites of sterile inflammation. Science (2010) 5.84
Intraluminal crawling of neutrophils to emigration sites: a molecularly distinct process from adhesion in the recruitment cascade. J Exp Med (2006) 3.38
Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo. Nat Med (2012) 3.38
A novel mechanism of rapid nuclear neutrophil extracellular trap formation in response to Staphylococcus aureus. J Immunol (2010) 3.20
Metabolic profiling of serum samples by 1H nuclear magnetic resonance spectroscopy as a potential diagnostic approach for septic shock. Crit Care Med (2014) 2.97
Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs. J Clin Invest (2003) 2.89
PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils. Nat Immunol (2008) 2.88
The neutrophil in vascular inflammation. Nat Med (2011) 2.84
Enhanced S-nitroso-albumin formation from inhaled NO during ischemia/reperfusion. Circ Res (2004) 2.75
An intracellular signaling hierarchy determines direction of migration in opposing chemotactic gradients. J Cell Biol (2002) 2.48
Functional innervation of hepatic iNKT cells is immunosuppressive following stroke. Science (2011) 2.44
Platelets express functional Toll-like receptor-4. Blood (2005) 2.37
TNF-alpha-secreting monocytes are recruited into the brain of cholestatic mice. Hepatology (2006) 2.23
Intravascular neutrophil extracellular traps capture bacteria from the bloodstream during sepsis. Cell Host Microbe (2012) 2.17
NETosis: how vital is it? Blood (2013) 2.11
An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells. Nat Immunol (2010) 2.03
Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis. J Clin Invest (2013) 2.03
Platelets contribute to the pathogenesis of experimental autoimmune encephalomyelitis. Circ Res (2012) 1.85
Interaction of CD44 and hyaluronan is the dominant mechanism for neutrophil sequestration in inflamed liver sinusoids. J Exp Med (2008) 1.84
The physiology of leukocyte recruitment: an in vivo perspective. J Immunol (2008) 1.84
Immune surveillance by the liver. Nat Immunol (2013) 1.79
LSP1 is an endothelial gatekeeper of leukocyte transendothelial migration. J Exp Med (2005) 1.72
Mice that exclusively express TLR4 on endothelial cells can efficiently clear a lethal systemic Gram-negative bacterial infection. J Clin Invest (2009) 1.70
TLR4 contributes to disease-inducing mechanisms resulting in central nervous system autoimmune disease. J Immunol (2004) 1.70
Real-time imaging of trapping and urease-dependent transmigration of Cryptococcus neoformans in mouse brain. J Clin Invest (2010) 1.67
Immune surveillance in the central nervous system. Nat Neurosci (2012) 1.63
IVIg therapy in brain inflammation: etiology-dependent differential effects on leucocyte recruitment. Brain (2004) 1.61
Targeting adhesion molecules as a potential mechanism of action for intravenous immunoglobulin. Circulation (2005) 1.60
Intravascular immunity: the host-pathogen encounter in blood vessels. Nat Rev Immunol (2009) 1.60
Real-time high resolution 3D imaging of the lyme disease spirochete adhering to and escaping from the vasculature of a living host. PLoS Pathog (2008) 1.59
Toll gates and traffic arteries: from endothelial TLR2 to atherosclerosis. Circ Res (2004) 1.59
PI3K accelerates, but is not required for, neutrophil chemotaxis to fMLP. J Cell Sci (2008) 1.54
Endothelial paxillin and focal adhesion kinase (FAK) play a critical role in neutrophil transmigration. Eur J Immunol (2012) 1.53
Role of CD44 and hyaluronan in neutrophil recruitment. J Immunol (2004) 1.53
Measuring chemotaxis and chemokinesis: the under-agarose cell migration assay. Sci STKE (2003) 1.50
Essential role for neutrophil recruitment to the liver in concanavalin A-induced hepatitis. J Immunol (2004) 1.49
A requirement for microglial TLR4 in leukocyte recruitment into brain in response to lipopolysaccharide. J Immunol (2006) 1.49
Nucleation of platelets with blood-borne pathogens on Kupffer cells precedes other innate immunity and contributes to bacterial clearance. Nat Immunol (2013) 1.46
Leukocyte migration is regulated by L-selectin endoproteolytic release. Immunity (2003) 1.42
Lipopolysaccharide-induced leukocyte-endothelial cell interactions: a role for CD14 versus toll-like receptor 4 within microvessels. J Immunol (2002) 1.38
Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection. Nat Immunol (2013) 1.37
Molecular mechanisms of leukocyte recruitment: organ-specific mechanisms of action. Thromb Haemost (2003) 1.36
Immune cell Toll-like receptor 4 is required for cardiac myocyte impairment during endotoxemia. Circ Res (2004) 1.35
Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome. J Neurosci (2009) 1.35
Molecular mechanisms involved in vascular interactions of the Lyme disease pathogen in a living host. PLoS Pathog (2008) 1.34
The role of TLR2 in vivo following challenge with Staphylococcus aureus and prototypic ligands. J Immunol (2006) 1.34
Neutrophils recruited to sites of infection protect from virus challenge by releasing neutrophil extracellular traps. Cell Host Microbe (2013) 1.33
Leukocyte PI3Kgamma and PI3Kdelta have temporally distinct roles for leukocyte recruitment in vivo. Blood (2007) 1.33
Modulating leukocyte recruitment in inflammation. J Allergy Clin Immunol (2007) 1.30
Neutrophils promote liver metastasis via Mac-1-mediated interactions with circulating tumor cells. Cancer Res (2012) 1.30
Toll-like receptor 2 ligands on the staphylococcal cell wall downregulate superantigen-induced T cell activation and prevent toxic shock syndrome. Nat Med (2009) 1.29
Overlapping roles of P-selectin and alpha 4 integrin to recruit leukocytes to the central nervous system in experimental autoimmune encephalomyelitis. J Immunol (2002) 1.25
Chemokines: sirens of neutrophil recruitment-but is it just one song? Immunity (2010) 1.24
Anti-adhesive effect of nitric oxide on Plasmodium falciparum cytoadherence under flow. Am J Pathol (2003) 1.23
Rules of recruitment for Th1 and Th2 lymphocytes in inflamed liver: a role for alpha-4 integrin and vascular adhesion protein-1. Immunity (2005) 1.23
Vav1 is essential for mechanotactic crawling and migration of neutrophils out of the inflamed microvasculature. J Immunol (2009) 1.23
Antibodies against neutrophil LY6G do not inhibit leukocyte recruitment in mice in vivo. Blood (2013) 1.23
Neutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrow. J Exp Med (2013) 1.21
Macrophages eliminate circulating tumor cells after monoclonal antibody therapy. J Clin Invest (2014) 1.21
Rod-Shaped monocytes patrol the brain vasculature and give rise to perivascular macrophages under the influence of proinflammatory cytokines and angiopoietin-2. J Neurosci (2008) 1.20
The use of spinning-disk confocal microscopy for the intravital analysis of platelet dynamics in response to systemic and local inflammation. PLoS One (2011) 1.17
Endothelial LSP1 is involved in endothelial dome formation, minimizing vascular permeability changes during neutrophil transmigration in vivo. Blood (2010) 1.15
Cytotoxic CD4+ T cells use granulysin to kill Cryptococcus neoformans, and activation of this pathway is defective in HIV patients. Blood (2006) 1.15
Fundamentally different roles for LFA-1, Mac-1 and alpha4-integrin in neutrophil chemotaxis. J Cell Sci (2005) 1.15
Leukocyte adhesion in the liver: distinct adhesion paradigm from other organs. J Hepatol (2007) 1.12
Molecular regulators of leucocyte chemotaxis during inflammation. Cardiovasc Res (2010) 1.11
Integrin-induced PIP5K1C kinase polarization regulates neutrophil polarization, directionality, and in vivo infiltration. Immunity (2010) 1.10
P-selectin can support both Th1 and Th2 lymphocyte rolling in the intestinal microvasculature. Am J Pathol (2005) 1.09
Use of CD44 by CD4+ Th1 and Th2 lymphocytes to roll and adhere. Blood (2006) 1.09
Neutrophil-active chemokines in in vivo imaging of neutrophil trafficking. Eur J Immunol (2012) 1.08
Reevaluation of P-selectin and alpha 4 integrin as targets for the treatment of experimental autoimmune encephalomyelitis. J Immunol (2006) 1.06
Cellular and molecular choreography of neutrophil recruitment to sites of sterile inflammation. J Mol Med (Berl) (2011) 1.05
Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules. Mol Microbiol (2012) 1.05
Endothelial domes encapsulate adherent neutrophils and minimize increases in vascular permeability in paracellular and transcellular emigration. PLoS One (2008) 1.05
Selective down-regulation of neutrophil Mac-1 in endotoxemic hepatic microcirculation via IL-10. J Immunol (2009) 1.04
Profound differences in leukocyte-endothelial cell responses to lipopolysaccharide versus lipoteichoic acid. J Immunol (2002) 1.03
Mast cell-expressed complement receptor, not TLR2, is the main detector of zymosan in peritonitis. Eur J Immunol (2007) 1.03
Inducible nitric oxide synthase (iNOS) in endotoxemia: chimeric mice reveal different cellular sources in various tissues. FASEB J (2002) 1.03
Loss of CD34 leads to exacerbated autoimmune arthritis through increased vascular permeability. J Immunol (2009) 1.03
Multichannel fluorescence spinning disk microscopy reveals early endogenous CD4 T cell recruitment in contact sensitivity via complement. J Immunol (2008) 1.03
Local coordination verses systemic disregulation: complexities in leukocyte recruitment revealed by local and systemic activation of TLR4 in vivo. J Leukoc Biol (2005) 1.01
Bone marrow-derived mast cells accumulate in the central nervous system during inflammation but are dispensable for experimental autoimmune encephalomyelitis pathogenesis. J Immunol (2009) 1.01
Different domains of Pseudomonas aeruginosa exoenzyme S activate distinct TLRs. J Immunol (2004) 1.01
Varying importance of soluble and membrane CD14 in endothelial detection of lipopolysaccharide. J Immunol (2008) 1.00
Cellular and molecular mechanisms underlying LPS-associated myocyte impairment. Am J Physiol Heart Circ Physiol (2005) 1.00
A critical temporal window for selectin-dependent CD4+ lymphocyte homing and initiation of late-phase inflammation in contact sensitivity. J Exp Med (2004) 0.99
Mast cells regulate the magnitude and the cytokine microenvironment of the contact hypersensitivity response. Am J Pathol (2008) 0.97
The role of selectins and integrins in adenovirus vector-induced neutrophil recruitment to the liver. Eur J Immunol (2002) 0.97
Damage-associated molecular patterns control neutrophil recruitment. J Innate Immun (2013) 0.96
Neutrophils and intravascular immunity in the liver during infection and sterile inflammation. Toxicol Pathol (2011) 0.96
Lipoteichoic acid induces unique inflammatory responses when compared to other toll-like receptor 2 ligands. PLoS One (2009) 0.95
Preventing the activation or cycling of the Rap1 GTPase alters adhesion and cytoskeletal dynamics and blocks metastatic melanoma cell extravasation into the lungs. Cancer Res (2010) 0.95