Published in Nat Neurosci on July 26, 2012
Therapeutic antiviral T cells noncytopathically clear persistently infected microglia after conversion into antigen-presenting cells. J Exp Med (2015) 1.52
The benefits and detriments of macrophages/microglia in models of multiple sclerosis. Clin Dev Immunol (2013) 1.14
TAM receptors affect adult brain neurogenesis by negative regulation of microglial cell activation. J Immunol (2013) 1.11
Caspase-8 promotes NLRP1/NLRP3 inflammasome activation and IL-1β production in acute glaucoma. Proc Natl Acad Sci U S A (2014) 1.07
Minimal NF-κB activity in neurons. Neuroscience (2013) 1.04
Neuroinflammation in Alzheimer's disease; A source of heterogeneity and target for personalized therapy. Neuroscience (2014) 1.01
Emerging strategies for treating brain metastases from breast cancer. Cancer Cell (2015) 1.00
Thinking laterally about neurodegenerative proteinopathies. J Clin Invest (2013) 0.99
Systemic inflammation and the brain: novel roles of genetic, molecular, and environmental cues as drivers of neurodegeneration. Front Cell Neurosci (2015) 0.96
New insights on human polyomavirus JC and pathogenesis of progressive multifocal leukoencephalopathy. Clin Dev Immunol (2013) 0.94
Neuropilin-1 mediates myeloid cell chemoattraction and influences retinal neuroimmune crosstalk. J Clin Invest (2014) 0.92
IL-33 ameliorates Alzheimer's disease-like pathology and cognitive decline. Proc Natl Acad Sci U S A (2016) 0.92
Neuro-endocrine networks controlling immune system in health and disease. Front Immunol (2014) 0.91
Rapid remodeling of tight junctions during paracellular diapedesis in a human model of the blood-brain barrier. J Immunol (2014) 0.91
IFN-Gamma Inhibits JC Virus Replication in Glial Cells by Suppressing T-Antigen Expression. PLoS One (2015) 0.89
HIV-1 target cells in the CNS. J Neurovirol (2014) 0.89
Prenatal alcohol exposure alters steady-state and activated gene expression in the adult rat brain. Alcohol Clin Exp Res (2015) 0.87
Metabolic syndrome and the immunological affair with the blood-brain barrier. Front Immunol (2015) 0.85
Autoantibodies and the immune hypothesis in psychotic brain diseases: challenges and perspectives. Clin Dev Immunol (2013) 0.85
Chronic murine toxoplasmosis is defined by subtle changes in neuronal connectivity. Dis Model Mech (2014) 0.85
The role of the immune system in central nervous system plasticity after acute injury. Neuroscience (2014) 0.84
Immune responses at brain barriers and implications for brain development and neurological function in later life. Front Integr Neurosci (2013) 0.84
HIV-1 transcriptional regulation in the central nervous system and implications for HIV cure research. J Neurovirol (2014) 0.84
TLR4-mediated brain inflammation halts neurogenesis: impact of hormonal replacement therapy. Front Cell Neurosci (2014) 0.83
Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination. Brain (2015) 0.83
Visualizing leukocyte trafficking in the living brain with 2-photon intravital microscopy. Front Cell Neurosci (2013) 0.83
Enlargement of cerebral ventricles as an early indicator of encephalomyelitis. PLoS One (2013) 0.82
Silencing of neurotropic flavivirus replication in the central nervous system by combining multiple microRNA target insertions in two distinct viral genome regions. Virology (2014) 0.82
Cutting Edge: CD99 Is a Novel Therapeutic Target for Control of T Cell-Mediated Central Nervous System Autoimmune Disease. J Immunol (2016) 0.81
Genetic variability in the rat Aplec C-type lectin gene cluster regulates lymphocyte trafficking and motor neuron survival after traumatic nerve root injury. J Neuroinflammation (2013) 0.81
Loss of chromosome Y (LOY) in blood cells is associated with increased risk for disease and mortality in aging men. Hum Genet (2017) 0.80
Reck enables cerebrovascular development by promoting canonical Wnt signaling. Development (2015) 0.80
Plasticity of primary microglia on micropatterned geometries and spontaneous long-distance migration in microfluidic channels. BMC Neurosci (2013) 0.80
NK cells promote neutrophil recruitment in the brain during sepsis-induced neuroinflammation. Sci Rep (2016) 0.79
The neuropeptide vasoactive intestinal peptide: direct effects on immune cells and involvement in inflammatory and autoimmune diseases. Acta Physiol (Oxf) (2014) 0.79
Glia in the cytokine-mediated onset of depression: fine tuning the immune response. Front Cell Neurosci (2015) 0.79
Adenosine receptor signaling: a key to opening the blood-brain door. Fluids Barriers CNS (2015) 0.79
Humanized mouse models for HIV-1 infection of the CNS. J Neurovirol (2014) 0.79
Regulation of T-lymphocyte motility, adhesion and de-adhesion by a cell surface mechanism directed by low density lipoprotein receptor-related protein 1 and endogenous thrombospondin-1. Immunology (2014) 0.79
Role of cytokine signaling during nervous system development. Int J Mol Sci (2013) 0.78
Enhanced resistance of CXCR3 deficient mice to ocular HSV-1 infection is due to control of replication in the brain ependyma. J Neuroimmunol (2014) 0.78
Do not judge a cell by its cover-diversity of CNS resident, adjoining and infiltrating myeloid cells in inflammation. Semin Immunopathol (2015) 0.78
Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease. Am J Hum Genet (2016) 0.78
Excessive cytokine response to rapid proliferation of highly pathogenic avian influenza viruses leads to fatal systemic capillary leakage in chickens. PLoS One (2013) 0.78
Splenocytes derived from young WT mice prevent AD progression in APPswe/PSENldE9 transgenic mice. Oncotarget (2015) 0.78
Humanized mice for HIV and AIDS research. Curr Opin Virol (2016) 0.78
Activation of the NLRP3 inflammasome in lipopolysaccharide-induced mouse fatigue and its relevance to chronic fatigue syndrome. J Neuroinflammation (2016) 0.77
Infectious hematopoietic necrosis virus (IHNV) persistence in Sockeye Salmon: influence on brain transcriptome and subsequent response to the viral mimic poly(I:C). BMC Genomics (2015) 0.77
Ninjurin1 deficiency attenuates susceptibility of experimental autoimmune encephalomyelitis in mice. J Biol Chem (2013) 0.77
Are Microglial Cells the Regulators of Lymphocyte Responses in the CNS? Front Cell Neurosci (2015) 0.77
Biomedical insights into cell adhesion and migration-from a viewpoint of central nervous system tumor immunology. Front Cell Dev Biol (2015) 0.77
Astrocytes: Integrative Regulators of Neuroinflammation in Stroke and Other Neurological Diseases. Neurotherapeutics (2016) 0.76
Improved recovery from spinal cord injury in rats with chronic parvovirus serotype-1a infection. Spinal Cord (2015) 0.76
Dynamics of spinal microglia repopulation following an acute depletion. Sci Rep (2016) 0.76
Immune Activation and HIV-Specific CD8(+) T Cells in Cerebrospinal Fluid of HIV Controllers and Noncontrollers. AIDS Res Hum Retroviruses (2016) 0.76
Validation of Flow Cytometry and Magnetic Bead-Based Methods to Enrich CNS Single Cell Suspensions for Quiescent Microglia. J Neuroimmune Pharmacol (2015) 0.76
Brain microbiota disruption within inflammatory demyelinating lesions in multiple sclerosis. Sci Rep (2016) 0.76
Modular and coordinated expression of immune system regulatory and signaling components in the developing and adult nervous system. Front Cell Neurosci (2015) 0.76
Neuroinvasion and Inflammation in Viral Central Nervous System Infections. Mediators Inflamm (2016) 0.76
Intracellular calcium dynamics in cortical microglia responding to focal laser injury in the PC::G5-tdT reporter mouse. Front Mol Neurosci (2015) 0.75
PKR deficiency alters E. coli-induced sickness behaviors but does not exacerbate neuroimmune responses or bacterial load. J Neuroinflammation (2015) 0.75
Alkylindole-sensitive receptors modulate microglial cell migration and proliferation. Glia (2015) 0.75
Autoimmune Profiling Reveals Peroxiredoxin 6 as a Candidate Traumatic Brain Injury Biomarker. J Neurotrauma (2015) 0.75
MiR-126 and miR-126* regulate shear-resistant firm leukocyte adhesion to human brain endothelium. Sci Rep (2017) 0.75
Delineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality. PLoS Pathog (2017) 0.75
Fermented Chinese formula Shuan-Tong-Ling attenuates ischemic stroke by inhibiting inflammation and apoptosis. Neural Regen Res (2017) 0.75
Contributions of the adaptive immune system to mood regulation: Mechanisms and pathways of neuroimmune interactions. Prog Neuropsychopharmacol Biol Psychiatry (2016) 0.75
Phenotypic dynamics of microglial and monocyte-derived cells in glioblastoma-bearing mice. Sci Rep (2016) 0.75
Deferoxamine regulates neuroinflammation and iron homeostasis in a mouse model of postoperative cognitive dysfunction. J Neuroinflammation (2016) 0.75
Co-culture model consisting of human brain microvascular endothelial and peripheral blood mononuclear cells. J Neurosci Methods (2016) 0.75
Targeting Endothelial Adhesion Molecule Transcription for Treatment of Inflammatory Disease: A Proof-of-Concept Study. Mediators Inflamm (2016) 0.75
The role of the immune system in neurofibromatosis type 1-associated nervous system tumors. CNS Oncol (2016) 0.75
Vitamin D inhibits the Staphylococcal enterotoxin B-induced expression of tumor necrosis factor in microglial cells. Immunol Res (2017) 0.75
The nervous and the immune systems: conspicuous physiological analogies. J Comp Physiol A Neuroethol Sens Neural Behav Physiol (2014) 0.75
Microglia in Glia-Neuron Co-cultures Exhibit Robust Phagocytic Activity Without Concomitant Inflammation or Cytotoxicity. Cell Mol Neurobiol (2015) 0.75
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science (2005) 14.43
Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science (2010) 12.15
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med (2007) 11.51
A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science (2012) 8.42
West Nile virus. Lancet Infect Dis (2002) 7.97
Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease. Neuron (2006) 6.38
C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE. Nat Immunol (2009) 5.97
TLR3 deficiency in patients with herpes simplex encephalitis. Science (2007) 5.86
Intravascular danger signals guide neutrophils to sites of sterile inflammation. Science (2010) 5.84
Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo. Science (1988) 5.56
Three or more routes for leukocyte migration into the central nervous system. Nat Rev Immunol (2003) 4.76
Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis. Nat Med (2005) 4.43
Down-regulation of the macrophage lineage through interaction with OX2 (CD200). Science (2000) 4.41
T-lymphocyte entry into the central nervous system. J Neurosci Res (1991) 4.28
Cryptococcosis in the acquired immunodeficiency syndrome. Ann Intern Med (1985) 4.25
TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice. Nat Med (2001) 3.84
Microglial interactions with synapses are modulated by visual experience. PLoS Biol (2010) 3.59
Hematopoietic origin of pathological grooming in Hoxb8 mutant mice. Cell (2010) 3.28
Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: a Review from the Research on Adverse Drug Events and Reports (RADAR) Project. Lancet Oncol (2009) 3.26
Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology. Nat Med (2008) 3.15
Chemokine receptor CCR5 promotes leukocyte trafficking to the brain and survival in West Nile virus infection. J Exp Med (2005) 3.08
Heterogeneity of CNS myeloid cells and their roles in neurodegeneration. Nat Neurosci (2011) 3.06
Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation? J Exp Med (1999) 2.84
Noncytotoxic lytic granule-mediated CD8+ T cell inhibition of HSV-1 reactivation from neuronal latency. Science (2008) 2.73
Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue. Ann Neurol (2004) 2.46
CD4+ T-cell responses are required for clearance of West Nile virus from the central nervous system. J Virol (2006) 2.44
West Nile virus neuroinvasive disease. Ann Neurol (2006) 2.42
A role for platelets and endothelial selectins in tumor necrosis factor-alpha-induced leukocyte recruitment in the brain microvasculature. Circ Res (2000) 2.41
Involvement of JC virus-infected mononuclear cells from the bone marrow and spleen in the pathogenesis of progressive multifocal leukoencephalopathy. N Engl J Med (1988) 2.32
CD8+ T cells require perforin to clear West Nile virus from infected neurons. J Virol (2006) 2.31
Microglia activation in retinal degeneration. J Leukoc Biol (2007) 2.31
Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease. J Neurosci (2011) 2.31
Human cerebrospinal fluid central memory CD4+ T cells: evidence for trafficking through choroid plexus and meninges via P-selectin. Proc Natl Acad Sci U S A (2003) 2.30
Basic principles of immunological surveillance of the normal central nervous system. Glia (2001) 2.13
Brain microglia constitutively express beta-2 integrins. J Neuroimmunol (1990) 2.09
IFN-gamma-producing gamma delta T cells help control murine West Nile virus infection. J Immunol (2003) 2.03
Migration of monocytes after intracerebral injection at entorhinal cortex lesion site. J Leukoc Biol (2012) 1.93
Autopsy findings in the acquired immune deficiency syndrome. JAMA (1984) 1.91
Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice. J Immunol (1998) 1.91
Regional neural activation defines a gateway for autoreactive T cells to cross the blood-brain barrier. Cell (2012) 1.90
Natalizumab and PML. Nat Neurosci (2005) 1.85
Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy. Proc Natl Acad Sci U S A (2009) 1.83
Expression of CCR7 in multiple sclerosis: implications for CNS immunity. Ann Neurol (2004) 1.83
Can the immune system be harnessed to repair the CNS? Nat Rev Neurosci (2008) 1.83
Distribution and phenotype of dendritic cells and resident tissue macrophages in the dura mater, leptomeninges, and choroid plexus of the rat brain as demonstrated in wholemount preparations. J Comp Neurol (1999) 1.81
Two subsets of dendritic cells are present in human cerebrospinal fluid. Brain (2001) 1.78
Leukocyte traffic in the central nervous system: the participants and their roles. Semin Immunol (1999) 1.73
CXCR3 mediates region-specific antiviral T cell trafficking within the central nervous system during West Nile virus encephalitis. J Immunol (2008) 1.61
CXCR4 antagonism increases T cell trafficking in the central nervous system and improves survival from West Nile virus encephalitis. Proc Natl Acad Sci U S A (2008) 1.60
Control of glial immune function by neurons. Glia (2001) 1.58
Microglia are the major cell type expressing MHC class II in human white matter. J Neurol Sci (1987) 1.50
Age-related alterations in the dynamic behavior of microglia. Aging Cell (2010) 1.49
Neurotrophins inhibit major histocompatibility class II inducibility of microglia: involvement of the p75 neurotrophin receptor. Proc Natl Acad Sci U S A (1998) 1.47
Like cops on the beat: the active role of resting microglia. Trends Neurosci (2005) 1.46
Illuminating viral infections in the nervous system. Nat Rev Immunol (2011) 1.46
Male donor-derived cells in the brains of female sex-mismatched bone marrow transplant recipients: a Y-chromosome specific in situ hybridization study. J Neuropathol Exp Neurol (1993) 1.46
Microglia induce CD4 T lymphocyte final effector function and death. J Exp Med (1996) 1.44
Immune control of herpes simplex virus during latency. Curr Opin Immunol (2004) 1.39
Protective autoimmunity: interferon-gamma enables microglia to remove glutamate without evoking inflammatory mediators. J Neurochem (2005) 1.37
CCR6 regulates EAE pathogenesis by controlling regulatory CD4+ T-cell recruitment to target tissues. Eur J Immunol (2009) 1.34
The interaction between herpes simplex virus and human immunodeficiency virus. Herpes (2004) 1.33
IL-12 production by central nervous system microglia is inhibited by astrocytes. J Immunol (1997) 1.31
Phenotype and functions of brain dendritic cells emerging during chronic infection of mice with Toxoplasma gondii. J Immunol (2000) 1.26
Role of cervical lymph nodes in the systemic humoral immune response to human serum albumin microinfused into rat cerebrospinal fluid. J Neuroimmunol (1989) 1.24
Generation of cytotoxic T cells against virus-infected human brain macrophages in a murine model of HIV-1 encephalitis. J Immunol (2002) 1.23
HIV patients developing primary CNS lymphoma lack EBV-specific CD4+ T cell function irrespective of absolute CD4+ T cell counts. PLoS Med (2007) 1.20
Major histocompatibility complex antigen expression on rat microglia following epidural kainic acid lesions. J Neurosci Res (1988) 1.19
Turnover of rat brain perivascular cells. Exp Neurol (2001) 1.18
Cryptococcus gattii isolates from the British Columbia cryptococcosis outbreak induce less protective inflammation in a murine model of infection than Cryptococcus neoformans. Infect Immun (2009) 1.18
Minocycline-mediated inhibition of microglia activation impairs oligodendrocyte progenitor cell responses and remyelination in a non-immune model of demyelination. J Neuroimmunol (2005) 1.17
Herpes simplex type I (HSV-1) infection of the nervous system: is an immune response a good thing? J Neuroimmunol (2009) 1.16
The central nervous system as an immunocompetent organ: role of glial cells in antigen presentation. J Immunol (1996) 1.16
Dendritic cells and dendritic-like microglia in focal cortical ischemia of the mouse brain. J Neuroimmunol (2002) 1.15
Perivascular cells act as scavengers in the cerebral perivascular spaces and remain distinct from pericytes, microglia and macrophages. Acta Neuropathol (1993) 1.14
Role of genetic background in P selectin-dependent immune surveillance of the central nervous system. J Neuroimmunol (2002) 1.12
How to drain without lymphatics? Dendritic cells migrate from the cerebrospinal fluid to the B-cell follicles of cervical lymph nodes. Blood (2005) 1.12
T-cells in the cerebrospinal fluid express a similar repertoire of inflammatory chemokine receptors in the absence or presence of CNS inflammation: implications for CNS trafficking. Clin Exp Immunol (2002) 1.12
Microglia are activated to become competent antigen presenting and effector cells in the inflammatory environment of the Theiler's virus model of multiple sclerosis. J Neuroimmunol (2003) 1.11
Functional analysis of macrophages, B cells and splenic dendritic cells as antigen-presenting cells in West Nile virus-specific murine T lymphocyte proliferation. Immunol Cell Biol (1991) 1.06
The Epstein-Barr virus and post-transplant lymphoproliferative disease: interplay of immunosuppression, EBV, and the immune system in disease pathogenesis. Transpl Infect Dis (2001) 1.06
Mice deficient for CCR6 fail to control chronic experimental autoimmune encephalomyelitis. J Neuroimmunol (2009) 1.02
Microglial progenitors with a high proliferative potential in the embryonic and adult mouse brain. Proc Natl Acad Sci U S A (1991) 1.01
Neurotrophins and the anti-inflammatory agents interleukin-4 (IL-4), IL-10, IL-11 and transforming growth factor-beta1 (TGF-beta1) down-regulate T cell costimulatory molecules B7 and CD40 on cultured rat microglia. J Neuroimmunol (1999) 0.99
Ultrastructural location of major histocompatibility complex (MHC) class II positive perivascular cells in histologically normal human brain. J Neuropathol Exp Neurol (1992) 0.98
Lymphocyte phenotype and subset distribution in normal cerebrospinal fluid. J Neuroimmunol (1995) 0.97
Induction of class I antigen processing components in oligodendroglia and microglia during viral encephalomyelitis. Glia (2008) 0.96
Thinking about HIV: the intersection of virus, neuroinflammation and cognitive dysfunction. Immunol Res (2010) 0.95
Encephalitogenic T cells use LFA-1 for transendothelial migration but not during capture and initial adhesion strengthening in healthy spinal cord microvessels in vivo. Eur J Immunol (2002) 0.94
Neuronal FasL induces cell death of encephalitogenic T lymphocytes. Brain Pathol (2000) 0.94
Primary central nervous system lymphomas in patients with AIDS. Ann Neurol (1988) 0.93
Bacillus Calmette-Guérin sequestered in the brain parenchyma escapes immune recognition. J Neuroimmunol (1998) 0.92
Reactive perivascular T-cell infiltrate predicts survival in primary central nervous system B-cell lymphomas. Br J Haematol (2007) 0.92
Immune surveillance of the human central nervous system (CNS): different migration pathways of immune cells through the blood-brain barrier and blood-cerebrospinal fluid barrier in healthy persons. Cytometry A (2006) 0.88
Immune surveillance of the normal human CNS takes place in dependence of the locoregional blood-brain barrier configuration and is mainly performed by CD3(+)/CD8(+) lymphocytes. Neuropathology (2010) 0.87
Characterization of epithelial V-like antigen in human choroid plexus epithelial cells: potential role in CNS immune surveillance. Neurosci Lett (2011) 0.83
Effect of highly active antiretroviral therapy on the incidence of HIV-associated malignancies at an urban medical center. J Acquir Immune Defic Syndr (1999) 0.81
Sell Memorial Lecture. Helping the body to cure itself: immune modulation by therapeutic vaccination for spinal cord injury. J Spinal Cord Med (2003) 0.79
AIDS-related primary brain lymphoma in Michigan, January 1990 to December 2000. AIDS Patient Care STDS (2002) 0.77
Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat Med (2007) 8.58
Neutrophil recruitment and function in health and inflammation. Nat Rev Immunol (2013) 7.10
Intravascular danger signals guide neutrophils to sites of sterile inflammation. Science (2010) 5.84
Intraluminal crawling of neutrophils to emigration sites: a molecularly distinct process from adhesion in the recruitment cascade. J Exp Med (2006) 3.38
Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo. Nat Med (2012) 3.38
A novel mechanism of rapid nuclear neutrophil extracellular trap formation in response to Staphylococcus aureus. J Immunol (2010) 3.20
Metabolic profiling of serum samples by 1H nuclear magnetic resonance spectroscopy as a potential diagnostic approach for septic shock. Crit Care Med (2014) 2.97
Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs. J Clin Invest (2003) 2.89
PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils. Nat Immunol (2008) 2.88
The neutrophil in vascular inflammation. Nat Med (2011) 2.84
Enhanced S-nitroso-albumin formation from inhaled NO during ischemia/reperfusion. Circ Res (2004) 2.75
An intracellular signaling hierarchy determines direction of migration in opposing chemotactic gradients. J Cell Biol (2002) 2.48
Functional innervation of hepatic iNKT cells is immunosuppressive following stroke. Science (2011) 2.44
Platelets express functional Toll-like receptor-4. Blood (2005) 2.37
TNF-alpha-secreting monocytes are recruited into the brain of cholestatic mice. Hepatology (2006) 2.23
Intravascular neutrophil extracellular traps capture bacteria from the bloodstream during sepsis. Cell Host Microbe (2012) 2.17
NETosis: how vital is it? Blood (2013) 2.11
An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells. Nat Immunol (2010) 2.03
Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis. J Clin Invest (2013) 2.03
Platelets contribute to the pathogenesis of experimental autoimmune encephalomyelitis. Circ Res (2012) 1.85
Interaction of CD44 and hyaluronan is the dominant mechanism for neutrophil sequestration in inflamed liver sinusoids. J Exp Med (2008) 1.84
The physiology of leukocyte recruitment: an in vivo perspective. J Immunol (2008) 1.84
Immune surveillance by the liver. Nat Immunol (2013) 1.79
LSP1 is an endothelial gatekeeper of leukocyte transendothelial migration. J Exp Med (2005) 1.72
Mice that exclusively express TLR4 on endothelial cells can efficiently clear a lethal systemic Gram-negative bacterial infection. J Clin Invest (2009) 1.70
TLR4 contributes to disease-inducing mechanisms resulting in central nervous system autoimmune disease. J Immunol (2004) 1.70
Real-time imaging of trapping and urease-dependent transmigration of Cryptococcus neoformans in mouse brain. J Clin Invest (2010) 1.67
IVIg therapy in brain inflammation: etiology-dependent differential effects on leucocyte recruitment. Brain (2004) 1.61
Targeting adhesion molecules as a potential mechanism of action for intravenous immunoglobulin. Circulation (2005) 1.60
Intravascular immunity: the host-pathogen encounter in blood vessels. Nat Rev Immunol (2009) 1.60
Real-time high resolution 3D imaging of the lyme disease spirochete adhering to and escaping from the vasculature of a living host. PLoS Pathog (2008) 1.59
Toll gates and traffic arteries: from endothelial TLR2 to atherosclerosis. Circ Res (2004) 1.59
PI3K accelerates, but is not required for, neutrophil chemotaxis to fMLP. J Cell Sci (2008) 1.54
Endothelial paxillin and focal adhesion kinase (FAK) play a critical role in neutrophil transmigration. Eur J Immunol (2012) 1.53
Role of CD44 and hyaluronan in neutrophil recruitment. J Immunol (2004) 1.53
Measuring chemotaxis and chemokinesis: the under-agarose cell migration assay. Sci STKE (2003) 1.50
Essential role for neutrophil recruitment to the liver in concanavalin A-induced hepatitis. J Immunol (2004) 1.49
A requirement for microglial TLR4 in leukocyte recruitment into brain in response to lipopolysaccharide. J Immunol (2006) 1.49
Nucleation of platelets with blood-borne pathogens on Kupffer cells precedes other innate immunity and contributes to bacterial clearance. Nat Immunol (2013) 1.46
Leukocyte migration is regulated by L-selectin endoproteolytic release. Immunity (2003) 1.42
Lipopolysaccharide-induced leukocyte-endothelial cell interactions: a role for CD14 versus toll-like receptor 4 within microvessels. J Immunol (2002) 1.38
Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection. Nat Immunol (2013) 1.37
Molecular mechanisms of leukocyte recruitment: organ-specific mechanisms of action. Thromb Haemost (2003) 1.36
Immune cell Toll-like receptor 4 is required for cardiac myocyte impairment during endotoxemia. Circ Res (2004) 1.35
Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome. J Neurosci (2009) 1.35
Molecular mechanisms involved in vascular interactions of the Lyme disease pathogen in a living host. PLoS Pathog (2008) 1.34
The role of TLR2 in vivo following challenge with Staphylococcus aureus and prototypic ligands. J Immunol (2006) 1.34
Neutrophils recruited to sites of infection protect from virus challenge by releasing neutrophil extracellular traps. Cell Host Microbe (2013) 1.33
Leukocyte PI3Kgamma and PI3Kdelta have temporally distinct roles for leukocyte recruitment in vivo. Blood (2007) 1.33
Neutrophils promote liver metastasis via Mac-1-mediated interactions with circulating tumor cells. Cancer Res (2012) 1.30
Modulating leukocyte recruitment in inflammation. J Allergy Clin Immunol (2007) 1.30
Toll-like receptor 2 ligands on the staphylococcal cell wall downregulate superantigen-induced T cell activation and prevent toxic shock syndrome. Nat Med (2009) 1.29
Overlapping roles of P-selectin and alpha 4 integrin to recruit leukocytes to the central nervous system in experimental autoimmune encephalomyelitis. J Immunol (2002) 1.25
Chemokines: sirens of neutrophil recruitment-but is it just one song? Immunity (2010) 1.24
Anti-adhesive effect of nitric oxide on Plasmodium falciparum cytoadherence under flow. Am J Pathol (2003) 1.23
Role of endothelial TLR4 for neutrophil recruitment into central nervous system microvessels in systemic inflammation. J Immunol (2009) 1.23
Rules of recruitment for Th1 and Th2 lymphocytes in inflamed liver: a role for alpha-4 integrin and vascular adhesion protein-1. Immunity (2005) 1.23
Vav1 is essential for mechanotactic crawling and migration of neutrophils out of the inflamed microvasculature. J Immunol (2009) 1.23
Antibodies against neutrophil LY6G do not inhibit leukocyte recruitment in mice in vivo. Blood (2013) 1.23
Neutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrow. J Exp Med (2013) 1.21
Macrophages eliminate circulating tumor cells after monoclonal antibody therapy. J Clin Invest (2014) 1.21
Rod-Shaped monocytes patrol the brain vasculature and give rise to perivascular macrophages under the influence of proinflammatory cytokines and angiopoietin-2. J Neurosci (2008) 1.20
The use of spinning-disk confocal microscopy for the intravital analysis of platelet dynamics in response to systemic and local inflammation. PLoS One (2011) 1.17
Endothelial LSP1 is involved in endothelial dome formation, minimizing vascular permeability changes during neutrophil transmigration in vivo. Blood (2010) 1.15
Cytotoxic CD4+ T cells use granulysin to kill Cryptococcus neoformans, and activation of this pathway is defective in HIV patients. Blood (2006) 1.15
Fundamentally different roles for LFA-1, Mac-1 and alpha4-integrin in neutrophil chemotaxis. J Cell Sci (2005) 1.15
Leukocyte adhesion in the liver: distinct adhesion paradigm from other organs. J Hepatol (2007) 1.12
Molecular regulators of leucocyte chemotaxis during inflammation. Cardiovasc Res (2010) 1.11
Integrin-induced PIP5K1C kinase polarization regulates neutrophil polarization, directionality, and in vivo infiltration. Immunity (2010) 1.10
P-selectin can support both Th1 and Th2 lymphocyte rolling in the intestinal microvasculature. Am J Pathol (2005) 1.09
Use of CD44 by CD4+ Th1 and Th2 lymphocytes to roll and adhere. Blood (2006) 1.09
Neutrophil-active chemokines in in vivo imaging of neutrophil trafficking. Eur J Immunol (2012) 1.08
Reevaluation of P-selectin and alpha 4 integrin as targets for the treatment of experimental autoimmune encephalomyelitis. J Immunol (2006) 1.06
Cellular and molecular choreography of neutrophil recruitment to sites of sterile inflammation. J Mol Med (Berl) (2011) 1.05
Endothelial domes encapsulate adherent neutrophils and minimize increases in vascular permeability in paracellular and transcellular emigration. PLoS One (2008) 1.05
Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules. Mol Microbiol (2012) 1.05
Selective down-regulation of neutrophil Mac-1 in endotoxemic hepatic microcirculation via IL-10. J Immunol (2009) 1.04
Inducible nitric oxide synthase (iNOS) in endotoxemia: chimeric mice reveal different cellular sources in various tissues. FASEB J (2002) 1.03
Multichannel fluorescence spinning disk microscopy reveals early endogenous CD4 T cell recruitment in contact sensitivity via complement. J Immunol (2008) 1.03
Mast cell-expressed complement receptor, not TLR2, is the main detector of zymosan in peritonitis. Eur J Immunol (2007) 1.03
Profound differences in leukocyte-endothelial cell responses to lipopolysaccharide versus lipoteichoic acid. J Immunol (2002) 1.03
Loss of CD34 leads to exacerbated autoimmune arthritis through increased vascular permeability. J Immunol (2009) 1.03
Local coordination verses systemic disregulation: complexities in leukocyte recruitment revealed by local and systemic activation of TLR4 in vivo. J Leukoc Biol (2005) 1.01
Different domains of Pseudomonas aeruginosa exoenzyme S activate distinct TLRs. J Immunol (2004) 1.01
Bone marrow-derived mast cells accumulate in the central nervous system during inflammation but are dispensable for experimental autoimmune encephalomyelitis pathogenesis. J Immunol (2009) 1.01
Varying importance of soluble and membrane CD14 in endothelial detection of lipopolysaccharide. J Immunol (2008) 1.00
Cellular and molecular mechanisms underlying LPS-associated myocyte impairment. Am J Physiol Heart Circ Physiol (2005) 1.00
A critical temporal window for selectin-dependent CD4+ lymphocyte homing and initiation of late-phase inflammation in contact sensitivity. J Exp Med (2004) 0.99
Mast cells regulate the magnitude and the cytokine microenvironment of the contact hypersensitivity response. Am J Pathol (2008) 0.97
The role of selectins and integrins in adenovirus vector-induced neutrophil recruitment to the liver. Eur J Immunol (2002) 0.97
Damage-associated molecular patterns control neutrophil recruitment. J Innate Immun (2013) 0.96
Neutrophils and intravascular immunity in the liver during infection and sterile inflammation. Toxicol Pathol (2011) 0.96
Recombinant PfEMP1 peptide inhibits and reverses cytoadherence of clinical Plasmodium falciparum isolates in vivo. Blood (2002) 0.95
Preventing the activation or cycling of the Rap1 GTPase alters adhesion and cytoskeletal dynamics and blocks metastatic melanoma cell extravasation into the lungs. Cancer Res (2010) 0.95
Lipoteichoic acid induces unique inflammatory responses when compared to other toll-like receptor 2 ligands. PLoS One (2009) 0.95
Complexity of inducible nitric oxide synthase: cellular source determines benefit versus toxicity. Circulation (2003) 0.93
Assessment of the safety and feasibility of administering antipyretic therapy in critically ill adults: a pilot randomized clinical trial. J Crit Care (2012) 0.93
GPI-linked endothelial CD14 contributes to the detection of LPS. Am J Physiol Heart Circ Physiol (2006) 0.93
Active Negative Pressure Peritoneal Therapy After Abbreviated Laparotomy: The Intraperitoneal Vacuum Randomized Controlled Trial. Ann Surg (2015) 0.93
Divergent roles of Toll-like receptor 2 in response to lipoteichoic acid and Staphylococcus aureus in vivo. Eur J Immunol (2010) 0.92