Published in J Immunol on September 28, 2009
The BEACH Domain Protein SPIRRIG Is Essential for Arabidopsis Salt Stress Tolerance and Functions as a Regulator of Transcript Stabilization and Localization. PLoS Biol (2015) 1.42
The BEACH is hot: a LYST of emerging roles for BEACH-domain containing proteins in human disease. Traffic (2013) 1.35
Age-dependent association between pulmonary tuberculosis and common TOX variants in the 8q12-13 linkage region. Am J Hum Genet (2013) 1.06
Neutral sphingomyelinase 2 (nSMase2) is the primary neutral sphingomyelinase isoform activated by tumour necrosis factor-α in MCF-7 cells. Biochem J (2011) 1.01
Factor associated with neutral sphingomyelinase activity mediates navigational capacity of leukocytes responding to wounds and infection: live imaging studies in zebrafish larvae. J Immunol (2012) 0.87
Genomic characterization of remission in juvenile idiopathic arthritis. Arthritis Res Ther (2013) 0.87
TNF-receptor-1 adaptor protein FAN mediates TNF-induced B16 melanoma motility and invasion. Br J Cancer (2013) 0.86
TNF-R1, an immune checkpoint in melanoma? Genes Cancer (2015) 0.75
Infectivity and insertional mutagenesis of endogenous retrovirus in autoimmune NZB and B/W mice. J Gen Virol (2015) 0.75
Regulation of autophagy by sphingosine kinase 1 and its role in cell survival during nutrient starvation. J Biol Chem (2006) 2.96
The key roles of elongases and desaturases in mammalian fatty acid metabolism: Insights from transgenic mice. Prog Lipid Res (2009) 2.80
Recommendations on the diagnosis and management of Niemann-Pick disease type C. Mol Genet Metab (2009) 2.78
Genotype of 86 Toxoplasma gondii isolates associated with human congenital toxoplasmosis, and correlation with clinical findings. J Infect Dis (2002) 2.78
Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota. Gut (2011) 2.50
Genotype of 88 Toxoplasma gondii isolates associated with toxoplasmosis in immunocompromised patients and correlation with clinical findings. J Infect Dis (2009) 2.33
Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy. J Biol Chem (2008) 2.31
Sparse canonical methods for biological data integration: application to a cross-platform study. BMC Bioinformatics (2009) 2.26
Long-term outcome of children with congenital toxoplasmosis. Am J Obstet Gynecol (2010) 1.66
Changes in transcriptional profiles are associated with early fruit tissue specialization in tomato. Plant Physiol (2005) 1.63
A physical and functional link between splicing factors promotes pre-mRNA 3' end processing. Nucleic Acids Res (2009) 1.60
Sphingosine kinase-1 as a chemotherapy sensor in prostate adenocarcinoma cell and mouse models. Cancer Res (2005) 1.59
OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals. Exp Cell Res (2007) 1.55
Toll-like receptors 2-deficient mice are protected against postischemic coronary endothelial dysfunction. Arterioscler Thromb Vasc Biol (2007) 1.54
Protein serine/threonine kinase StkP positively controls virulence and competence in Streptococcus pneumoniae. Infect Immun (2004) 1.53
Characterization of a eukaryotic type serine/threonine protein kinase and protein phosphatase of Streptococcus pneumoniae and identification of kinase substrates. FEBS J (2005) 1.52
Engraftment of human T, B and NK cells in CB.17 SCID/beige mice by transfer of human spleen cells. Transpl Immunol (2005) 1.51
Gene and metabolite regulatory network analysis of early developing fruit tissues highlights new candidate genes for the control of tomato fruit composition and development. Plant Physiol (2009) 1.50
17Beta-estradiol promotes TLR4-triggered proinflammatory mediator production through direct estrogen receptor alpha signaling in macrophages in vivo. J Immunol (2010) 1.40
Automated SNP detection in expressed sequence tags: statistical considerations and application to maritime pine sequences. Plant Mol Biol (2004) 1.32
Is autophagy the key mechanism by which the sphingolipid rheostat controls the cell fate decision? Autophagy (2007) 1.28
Sphingomyelin hydrolysis during apoptosis. Biochim Biophys Acta (2002) 1.27
GDP-D-mannose 3,5-epimerase (GME) plays a key role at the intersection of ascorbate and non-cellulosic cell-wall biosynthesis in tomato. Plant J (2009) 1.27
Incidence and natural history of mucopolysaccharidosis type III in France and comparison with United Kingdom and Greece. Am J Med Genet A (2011) 1.26
The sphingosine 1-phosphate receptor S1P2 triggers hepatic wound healing. FASEB J (2007) 1.25
Chronic estradiol administration in vivo promotes the proinflammatory response of macrophages to TLR4 activation: involvement of the phosphatidylinositol 3-kinase pathway. J Immunol (2008) 1.24
Somatostatin receptor subtype 2 sensitizes human pancreatic cancer cells to death ligand-induced apoptosis. Proc Natl Acad Sci U S A (2002) 1.23
The transactivating function 1 of estrogen receptor alpha is dispensable for the vasculoprotective actions of 17beta-estradiol. Proc Natl Acad Sci U S A (2009) 1.23
Silencing of the mitochondrial ascorbate synthesizing enzyme L-galactono-1,4-lactone dehydrogenase affects plant and fruit development in tomato. Plant Physiol (2007) 1.21
Overexpression of sphingosine kinase 1 is an oncogenic event in erythroleukemic progression. Blood (2005) 1.20
The TLR-mediated response of plasmacytoid dendritic cells is positively regulated by estradiol in vivo through cell-intrinsic estrogen receptor α signaling. Blood (2011) 1.19
Danon's disease (X-linked vacuolar cardiomyopathy and myopathy): a case with a novel Lamp-2 gene mutation. Neuromuscul Disord (2002) 1.13
RegR, a global LacI/GalR family regulator, modulates virulence and competence in Streptococcus pneumoniae. Infect Immun (2003) 1.13
Spinal muscular atrophy associated with progressive myoclonic epilepsy is caused by mutations in ASAH1. Am J Hum Genet (2012) 1.11
Disruption of sphingosine 1-phosphate lyase confers resistance to chemotherapy and promotes oncogenesis through Bcl-2/Bcl-xL upregulation. Cancer Res (2009) 1.11
Oxidized LDL-induced smooth muscle cell proliferation involves the EGF receptor/PI-3 kinase/Akt and the sphingolipid signaling pathways. Arterioscler Thromb Vasc Biol (2002) 1.11
The MicAB two-component signaling system is involved in virulence of Streptococcus pneumoniae. Infect Immun (2003) 1.10
Ceramide-induced autophagy: to junk or to protect cells? Autophagy (2009) 1.09
Detection of intracellular reactive oxygen species in cultured cells using fluorescent probes. Methods Enzymol (2002) 1.09
Low doses of bisphenol A induce gene expression related to lipid synthesis and trigger triglyceride accumulation in adult mouse liver. Hepatology (2011) 1.08
Striking phenotypic variability in two familial cases of myosin storage myopathy with a MYH7 Leu1793pro mutation. Neuromuscul Disord (2009) 1.07
Ceramide in apoptosis: a revisited role. Neurochem Res (2002) 1.06
Apelin treatment increases complete Fatty Acid oxidation, mitochondrial oxidative capacity, and biogenesis in muscle of insulin-resistant mice. Diabetes (2011) 1.05
Transcriptome analysis of bud burst in sessile oak (Quercus petraea). New Phytol (2006) 1.04
Lysosomes and lysosomal proteins in cancer cell death (new players of an old struggle). Biochim Biophys Acta (2005) 1.04
Glutathione peroxidase-1 protects from CD95-induced apoptosis. J Biol Chem (2002) 1.03
Functions of sphingolipid metabolism in mammals--lessons from genetic defects. Biochim Biophys Acta (2008) 1.03
Estrogen receptor alpha signaling in inflammatory leukocytes is dispensable for 17beta-estradiol-mediated inhibition of experimental autoimmune encephalomyelitis. J Immunol (2004) 1.03
IL-6 deficiency attenuates murine diet-induced non-alcoholic steatohepatitis. PLoS One (2009) 1.01
Caspase-10 triggers Bid cleavage and caspase cascade activation in FasL-induced apoptosis. J Biol Chem (2005) 1.00
Characterization of the dihydrolipoamide dehydrogenase from Streptococcus pneumoniae and its role in pneumococcal infection. Mol Microbiol (2002) 1.00
Current thoughts on the phosphatidylinositol transfer protein family. FEBS Lett (2002) 0.99
Sphingolipids as modulators of cancer cell death: potential therapeutic targets. Biochim Biophys Acta (2006) 0.98
N-acetylcysteine prevents the deleterious effect of tumor necrosis factor-(alpha) on calcium transients and contraction in adult rat cardiomyocytes. Circulation (2004) 0.98
Endothelial estrogen receptor-alpha plays a crucial role in the atheroprotective action of 17beta-estradiol in low-density lipoprotein receptor-deficient mice. Circulation (2009) 0.98
Design, synthesis and activity as acid ceramidase inhibitors of 2-oxooctanoyl and N-oleoylethanolamine analogues. Chem Phys Lipids (2006) 0.96
Transcriptional regulation of hepatic fatty acid metabolism. Subcell Biochem (2008) 0.96
Synthesis of a novel ceramide analogue and its use in a high-throughput fluorogenic assay for ceramidases. Chembiochem (2007) 0.96
IL-13 attenuates gastrointestinal candidiasis in normal and immunodeficient RAG-2(-/-) mice via peroxisome proliferator-activated receptor-gamma activation. J Immunol (2008) 0.95
Genome-wide analysis of intraspecific DNA polymorphism in 'Micro-Tom', a model cultivar of tomato (Solanum lycopersicum). Plant Cell Physiol (2013) 0.95
Estrogen enhances susceptibility to experimental autoimmune myasthenia gravis by promoting type 1-polarized immune responses. J Immunol (2005) 0.95
Proteomic analysis of S-acylated proteins in human B cells reveals palmitoylation of the immune regulators CD20 and CD23. PLoS One (2012) 0.95
On-tissue localization of ceramides and other sphingolipids by MALDI mass spectrometry imaging. Anal Chem (2014) 0.94
Systemic ceramide accumulation leads to severe and varied pathological consequences. EMBO Mol Med (2013) 0.94
A simple fluorogenic method for determination of acid ceramidase activity and diagnosis of Farber disease. J Lipid Res (2010) 0.94
Potential roles of membrane fluidity and ceramide in hyperthermia and alcohol stimulation of TRAIL apoptosis. Apoptosis (2007) 0.93
Phenylbutyrate up-regulates the adrenoleukodystrophy-related gene as a nonclassical peroxisome proliferator. J Cell Biol (2005) 0.93
Mice deficient in Neu4 sialidase exhibit abnormal ganglioside catabolism and lysosomal storage. Hum Mol Genet (2008) 0.93
The natural marine anhydrophytosphingosine, Jaspine B, induces apoptosis in melanoma cells by interfering with ceramide metabolism. Biochem Pharmacol (2009) 0.93
Neutral sphingomyelinase inhibition participates to the benefits of N-acetylcysteine treatment in post-myocardial infarction failing heart rats. J Mol Cell Cardiol (2007) 0.93
Estradiol promotes functional responses in inflammatory and steady-state dendritic cells through differential requirement for activation function-1 of estrogen receptor α. J Immunol (2013) 0.93
Ceramide production associated with retinal apoptosis after retinal detachment. Graefes Arch Clin Exp Ophthalmol (2008) 0.92
A MANBA mutation resulting in residual beta-mannosidase activity associated with severe leukoencephalopathy: a possible pseudodeficiency variant. BMC Med Genet (2009) 0.91
Regulation of autophagy by sphingolipids. Anticancer Agents Med Chem (2011) 0.91
The StkP/PhpP signaling couple in Streptococcus pneumoniae: cellular organization and physiological characterization. J Bacteriol (2009) 0.91
Acid ceramidase expression modulates the sensitivity of A375 melanoma cells to dacarbazine. J Biol Chem (2011) 0.91
Sphingolipids in macroautophagy. Methods Mol Biol (2008) 0.90
The French Gaucher's disease registry: clinical characteristics, complications and treatment of 562 patients. Orphanet J Rare Dis (2012) 0.89
Genotype-dependent response to carbon availability in growing tomato fruit. Plant Cell Environ (2010) 0.89
LuxS impacts on LytA-dependent autolysis and on competence in Streptococcus pneumoniae. Microbiology (2006) 0.89
IPPRED: server for proteins interactions inference. Bioinformatics (2003) 0.89
Role of FAN in tumor necrosis factor-alpha and lipopolysaccharide-induced interleukin-6 secretion and lethality in D-galactosamine-sensitized mice. J Biol Chem (2004) 0.89