Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer.

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Published in Cancer Res on October 13, 2009

Authors

Lei Xu1, Dan G Duda, Emmanuelle di Tomaso, Marek Ancukiewicz, Daniel C Chung, Gregory Y Lauwers, Rekha Samuel, Paul Shellito, Brian G Czito, Pei-Chun Lin, Martin Poleski, Rex Bentley, Jeffrey W Clark, Christopher G Willett, Rakesh K Jain

Author Affiliations

1: Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.

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