Published in Hum Genet on October 27, 2009
The host genetic diversity in malaria infection. J Trop Med (2012) 1.08
Age-related susceptibility to severe malaria associated with galectin-2 in highland Papuans. J Infect Dis (2010) 0.82
NOS2 variants reveal a dual genetic control of nitric oxide levels, susceptibility to Plasmodium infection, and cerebral malaria. Infect Immun (2013) 0.78
Relationship of bovine NOS2 gene polymorphisms to the risk of bovine tuberculosis in Holstein cattle. J Vet Med Sci (2015) 0.78
Nitric oxide in liver fibrosis: The role of inducible nitric oxide synthase. Clin Mol Hepatol (2015) 0.78
Polymorphisms in host genes encoding NOSII, C-reactive protein, and adhesion molecules thrombospondin and E-selectin are risk factors for Plasmodium falciparum malaria in India. Eur J Clin Microbiol Infect Dis (2015) 0.77
A non-synonymous SNP in the NOS2 associated with septic shock in patients with sepsis in Chinese populations. Hum Genet (2012) 0.77
Inducible nitric oxide synthase (iNOS) regulatory region variation in non-human primates. Infect Genet Evol (2015) 0.76
Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics (1989) 73.50
A new statistical method for haplotype reconstruction from population data. Am J Hum Genet (2001) 59.30
The Interaction of Selection and Linkage. I. General Considerations; Heterotic Models. Genetics (1964) 35.22
Hypervariable 'minisatellite' regions in human DNA. Nature (1985) 31.03
A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet (2003) 26.59
BLAST 2 Sequences, a new tool for comparing protein and nucleotide sequences. FEMS Microbiol Lett (1999) 25.40
Statistical properties of the number of recombination events in the history of a sample of DNA sequences. Genetics (1985) 20.92
Modeling linkage disequilibrium and identifying recombination hotspots using single-nucleotide polymorphism data. Genetics (2003) 17.73
Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis. Nat Genet (1999) 17.09
Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex. Nat Genet (2001) 15.53
The L-arginine-nitric oxide pathway. N Engl J Med (1993) 14.38
Clinical features and prognostic indicators in paediatric cerebral malaria: a study of 131 comatose Malawian children. Q J Med (1989) 10.29
Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase. Am J Hum Genet (1998) 7.56
Nitric oxide: a physiologic messenger molecule. Annu Rev Biochem (1994) 5.11
Perspectives series: host/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activity. J Clin Invest (1997) 4.62
Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet (2009) 4.30
Structure of chi hotspots of generalized recombination. Cell (1981) 4.19
CENSOR--a program for identification and elimination of repetitive elements from DNA sequences. Comput Chem (1996) 4.09
Multiple comparison procedures updated. Clin Exp Pharmacol Physiol (1998) 3.92
Immunological processes in malaria pathogenesis. Nat Rev Immunol (2005) 3.80
Repeats in genomic DNA: mining and meaning. Curr Opin Struct Biol (1998) 3.78
SNP frequencies in human genes an excess of rare alleles and differing modes of selection. Trends Genet (2000) 3.78
Inducible nitric oxide synthase: what difference does it make? J Clin Invest (1997) 3.72
A recombination hotspot responsible for two inherited peripheral neuropathies is located near a mariner transposon-like element. Nat Genet (1996) 3.45
Impaired nitric oxide bioavailability and L-arginine reversible endothelial dysfunction in adults with falciparum malaria. J Exp Med (2007) 3.13
Recombinational and mutational hotspots within the human lipoprotein lipase gene. Am J Hum Genet (2000) 2.83
Angiopoietin-2 is associated with decreased endothelial nitric oxide and poor clinical outcome in severe falciparum malaria. Proc Natl Acad Sci U S A (2008) 2.80
Nitric oxide in Tanzanian children with malaria: inverse relationship between malaria severity and nitric oxide production/nitric oxide synthase type 2 expression. J Exp Med (1996) 2.75
Maternal malaria and gravidity interact to modify infant susceptibility to malaria. PLoS Med (2005) 2.72
A new NOS2 promoter polymorphism associated with increased nitric oxide production and protection from severe malaria in Tanzanian and Kenyan children. Lancet (2002) 2.69
The detection of linkage disequilibrium in molecular sequence data. Genetics (1995) 2.39
Multiple NF-kappaB enhancer elements regulate cytokine induction of the human inducible nitric oxide synthase gene. J Biol Chem (1998) 2.35
Low nitric oxide bioavailability contributes to the genesis of experimental cerebral malaria. Nat Med (2006) 2.33
Minimal haplotype tagging. Proc Natl Acad Sci U S A (2003) 2.28
Hypervariable minisatellite DNA is a hotspot for homologous recombination in human cells. Cell (1990) 2.11
Impact of the -308 TNF promoter polymorphism on the transcriptional regulation of the TNF gene: relevance to disease. J Leukoc Biol (1999) 1.87
Cytokine-mediated transcriptional induction of the human inducible nitric oxide synthase gene requires both activator protein 1 and nuclear factor kappaB-binding sites. J Biol Chem (1998) 1.81
Complex regulation of human inducible nitric oxide synthase gene transcription by Stat 1 and NF-kappa B. Proc Natl Acad Sci U S A (2001) 1.78
Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: initial analysis of the human NOS2 promoter. Proc Natl Acad Sci U S A (1996) 1.71
Polymorphism in promoter region of inducible nitric oxide synthase gene and protection against malaria. Lancet (1998) 1.65
A novel gene, Translin, encodes a recombination hotspot binding protein associated with chromosomal translocations. Nat Genet (1995) 1.64
Molecular cloning, structure, and chromosomal localization of the human inducible nitric oxide synthase gene. J Biol Chem (1994) 1.64
Nitric oxide production and nitric oxide synthase type 2 expression by human mononuclear phagocytes: a review. Mol Med (1998) 1.62
Cytokine-induced changes in chromatin structure and in vivo footprints in the inducible NOS promoter. Am J Physiol Lung Cell Mol Physiol (2001) 1.49
Nitric oxide and parasitic disease. Adv Parasitol (1996) 1.38
Inducible nitric oxide synthase polymorphism and fatal cerebral malaria. Lancet (1998) 1.35
Analysis of the cytokine-stimulated human inducible nitric oxide synthase (iNOS) gene: characterization of differences between human and mouse iNOS promoters. Biochem Biophys Res Commun (1998) 1.29
Arginine, nitric oxide, carbon monoxide, and endothelial function in severe malaria. Curr Opin Infect Dis (2008) 1.27
Cellular tumor necrosis factor, gamma interferon, and interleukin-6 responses as correlates of immunity and risk of clinical Plasmodium falciparum malaria in children from Papua New Guinea. Infect Immun (2009) 1.20
Host polymorphisms and the incidence of malaria in Ugandan children. Am J Trop Med Hyg (2004) 1.18
Nitric oxide: a novel mediator of inflammation. Proc Soc Exp Biol Med (1995) 1.11
Blood mononuclear cell nitric oxide production and plasma cytokine levels in healthy gabonese children with prior mild or severe malaria. Infect Immun (1999) 1.02
Nucleotide and haplotypic diversity of the NOS2A promoter region and its relationship to cerebral malaria. Hum Genet (2003) 1.00
Nitric oxide synthase 2 promoter polymorphisms and systemic lupus erythematosus in african-americans. J Rheumatol (2003) 0.99
Nitric oxide synthase type 2 promoter polymorphisms, nitric oxide production, and disease severity in Tanzanian children with malaria. J Infect Dis (1999) 0.98
Transcriptional regulation of human inducible nitric oxide synthase gene in an intestinal epithelial cell line. Am J Physiol (1997) 0.97
Promoter analysis of human inducible nitric oxide synthase gene associated with cardiovascular homeostasis. Biochem Biophys Res Commun (1994) 0.96
Nitric oxide production and mononuclear cell nitric oxide synthase activity in malaria-tolerant Papuan adults. Infect Immun (2003) 0.91
Haplotypic relationship between SNP and microsatellite markers at the NOS2A locus in two populations. Genes Immun (2003) 0.89
Synergistic regulation of inducible nitric oxide synthase gene by CCAAT/enhancer-binding protein beta and nuclear factor-kappaB in hepatocytes. Genes Cells (1998) 0.89
iNOS promoter variants and severe malaria in Ghanaian children. Trop Med Int Health (2004) 0.88
Evolution of a homopurine-homopyrimidine pentanucleotide repeat sequence upstream of the human inducible nitric oxide synthase gene. Gene (1997) 0.88
Inducible nitric oxide synthase (NOS2) promoter CCTTT repeat polymorphism: relationship to in vivo nitric oxide production/NOS activity in an asymptomatic malaria-endemic population. Am J Trop Med Hyg (2003) 0.86
Analysis of expression and promoter function of the human inducible nitric oxide synthase gene in DLD-1 cells and monkey hepatocytes. Biochim Biophys Acta (1997) 0.81
Human- and mouse-inducible nitric oxide synthase promoters require activation of phosphatidylcholine-specific phospholipase C and NF-kappa B. Mol Med (1997) 0.80
Analysis of polymorphic sites in the promoter of the nitric oxide synthase 2 gene. Biochem Biophys Res Commun (2005) 0.77
Vivax malaria: neglected and not benign. Am J Trop Med Hyg (2007) 10.16
WHO, the Global Fund, and medical malpractice in malaria treatment. Lancet (2004) 9.27
Multidrug-resistant Plasmodium vivax associated with severe and fatal malaria: a prospective study in Papua, Indonesia. PLoS Med (2008) 6.61
Malaria: progress, perils, and prospects for eradication. J Clin Invest (2008) 6.54
New developments in Plasmodium vivax malaria: severe disease and the rise of chloroquine resistance. Curr Opin Infect Dis (2009) 4.00
Malaria in pregnancy: pathogenesis and immunity. Lancet Infect Dis (2007) 3.88
Iron deficiency protects against severe Plasmodium falciparum malaria and death in young children. Clin Infect Dis (2012) 3.69
Immunity to malaria after administration of ultra-low doses of red cells infected with Plasmodium falciparum. Lancet (2002) 3.21
Impaired nitric oxide bioavailability and L-arginine reversible endothelial dysfunction in adults with falciparum malaria. J Exp Med (2007) 3.13
Artemisinin combination therapy for vivax malaria. Lancet Infect Dis (2010) 3.08
The relationship between age and the manifestations of and mortality associated with severe malaria. Clin Infect Dis (2008) 3.05
Antibodies that inhibit Plasmodium falciparum adhesion to chondroitin sulfate A are associated with increased birth weight and the gestational age of newborns. Infect Immun (2003) 3.05
Adverse pregnancy outcomes in an area where multidrug-resistant plasmodium vivax and Plasmodium falciparum infections are endemic. Clin Infect Dis (2008) 3.01
Decreased susceptibility to Plasmodium falciparum infection in pregnant women with iron deficiency. J Infect Dis (2008) 2.82
Angiopoietin-2 is associated with decreased endothelial nitric oxide and poor clinical outcome in severe falciparum malaria. Proc Natl Acad Sci U S A (2008) 2.80
Maternal malaria and gravidity interact to modify infant susceptibility to malaria. PLoS Med (2005) 2.72
A new NOS2 promoter polymorphism associated with increased nitric oxide production and protection from severe malaria in Tanzanian and Kenyan children. Lancet (2002) 2.69
Chloroquine resistant Plasmodium vivax: in vitro characterisation and association with molecular polymorphisms. PLoS One (2007) 2.66
Intermittent treatment to prevent pregnancy malaria does not confer benefit in an area of widespread drug resistance. Clin Infect Dis (2011) 2.56
Moderate-intensity exercise reduces the incidence of colds among postmenopausal women. Am J Med (2006) 2.53
Therapeutic efficacies of artesunate-sulfadoxine-pyrimethamine and chloroquine-sulfadoxine-pyrimethamine in vivax malaria pilot studies: relationship to Plasmodium vivax dhfr mutations. Antimicrob Agents Chemother (2002) 2.52
Patterns of microRNA expression characterize stages of human B-cell differentiation. Blood (2009) 2.46
Malaria morbidity in Papua Indonesia, an area with multidrug resistant Plasmodium vivax and Plasmodium falciparum. Malar J (2008) 2.41
Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32. Nat Genet (2010) 2.37
Melioidosis epidemiology and risk factors from a prospective whole-population study in northern Australia. Trop Med Int Health (2004) 2.36
Malaria in pregnancy. BJOG (2005) 2.35
Unmetabolized folic acid in plasma is associated with reduced natural killer cell cytotoxicity among postmenopausal women. J Nutr (2006) 2.25
The World Bank: false financial and statistical accounts and medical malpractice in malaria treatment. Lancet (2006) 2.22
A prospective comparative study of knowlesi, falciparum, and vivax malaria in Sabah, Malaysia: high proportion with severe disease from Plasmodium knowlesi and Plasmodium vivax but no mortality with early referral and artesunate therapy. Clin Infect Dis (2012) 2.20
Cost-effectiveness study of three antimalarial drug combinations in Tanzania. PLoS Med (2006) 2.18
Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. Blood (2010) 2.15
Effect of exercise on serum estrogens in postmenopausal women: a 12-month randomized clinical trial. Cancer Res (2004) 2.14
Severe Plasmodium knowlesi malaria in a tertiary care hospital, Sabah, Malaysia. Emerg Infect Dis (2011) 2.11
Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection. PLoS Med (2009) 2.11
Parasite burden and severity of malaria in Tanzanian children. N Engl J Med (2014) 2.07
Replication of mitochondrial DNA occurs by strand displacement with alternative light-strand origins, not via a strand-coupled mechanism. Genes Dev (2005) 1.94
p47 GTPases regulate Toxoplasma gondii survival in activated macrophages. Infect Immun (2005) 1.93
The role of biomechanics and inflammation in cartilage injury and repair. Clin Orthop Relat Res (2004) 1.89
Relationship of cell-free hemoglobin to impaired endothelial nitric oxide bioavailability and perfusion in severe falciparum malaria. J Infect Dis (2009) 1.86
Low plasma arginine concentrations in children with cerebral malaria and decreased nitric oxide production. Lancet (2003) 1.86
Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. Nat Genet (2013) 1.85
The anaemia of Plasmodium vivax malaria. Malar J (2012) 1.82
Malaria in pregnancy and the endemicity spectrum: what can we learn? Trends Parasitol (2004) 1.81
A novel histological grading scheme for placental malaria applied in areas of high and low malaria transmission. J Infect Dis (2010) 1.79
Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL. Blood (2010) 1.79
Exercise effect on weight and body fat in men and women. Obesity (Silver Spring) (2007) 1.68
Increasing incidence of Plasmodium knowlesi malaria following control of P. falciparum and P. vivax Malaria in Sabah, Malaysia. PLoS Negl Trop Dis (2013) 1.68
Limitations of microscopy to differentiate Plasmodium species in a region co-endemic for Plasmodium falciparum, Plasmodium vivax and Plasmodium knowlesi. Malar J (2013) 1.66
Is plasma arginine concentration decreased in patients with sepsis? A systematic review and meta-analysis. Crit Care Med (2011) 1.63
Correlates of circulating C-reactive protein and serum amyloid A concentrations in breast cancer survivors. Breast Cancer Res Treat (2008) 1.60
Cardiovascular disease in the developing world: prevalences, patterns, and the potential of early disease detection. J Am Coll Cardiol (2012) 1.59
Hypertension and maternal-fetal conflict during placental malaria. PLoS Med (2006) 1.56
Real-time quantitative reverse transcription PCR for monitoring of blood-stage Plasmodium falciparum infections in malaria human challenge trials. Am J Trop Med Hyg (2012) 1.55
A simple, valid, numerical score for grading chest x-ray severity in adult smear-positive pulmonary tuberculosis. Thorax (2010) 1.55
A simple score to predict the outcome of severe malaria in adults. Clin Infect Dis (2010) 1.54
Superresolution fluorescence imaging of mitochondrial nucleoids reveals their spatial range, limits, and membrane interaction. Mol Cell Biol (2011) 1.52
Phase II study of cenersen, an antisense inhibitor of p53, in combination with fludarabine, cyclophosphamide and rituximab for high-risk chronic lymphocytic leukemia. Leuk Lymphoma (2011) 1.51
Outcomes of patients with melioidosis treated with meropenem. Antimicrob Agents Chemother (2004) 1.48
Deaths due to Plasmodium knowlesi malaria in Sabah, Malaysia: association with reporting as Plasmodium malariae and delayed parenteral artesunate. Malar J (2012) 1.47
Parasite-dependent expansion of TNF receptor II-positive regulatory T cells with enhanced suppressive activity in adults with severe malaria. PLoS Pathog (2009) 1.46
Granzyme B expression by CD8+ T cells is required for the development of experimental cerebral malaria. J Immunol (2011) 1.46
Adjunctive granulocyte colony-stimulating factor for treatment of septic shock due to melioidosis. Clin Infect Dis (2003) 1.44
Plasmodium falciparum: chondroitin sulfate A is the major receptor for adhesion of parasitized erythrocytes in the placenta. Exp Parasitol (2006) 1.44
Plasmodium knowlesi malaria in children. Emerg Infect Dis (2011) 1.42
Eosinophils in severe sepsis in northern australia: do the usual rules apply in the tropics? Crit Care Med (2013) 1.42
Vitamin D insufficiency in a multiethnic cohort of breast cancer survivors. Am J Clin Nutr (2008) 1.41
Pneumonia risk stratification in tropical Australia: does the SMART-COP score apply? Med J Aust (2010) 1.41
Epidemiology of Plasmodium knowlesi malaria in north-east Sabah, Malaysia: family clusters and wide age distribution. Malar J (2012) 1.40
High deformability of Plasmodium vivax-infected red blood cells under microfluidic conditions. J Infect Dis (2009) 1.40
Malaria tolerance--for whom the cell tolls? Trends Parasitol (2006) 1.40
CD38 variation as a prognostic factor in chronic lymphocytic leukemia. Leuk Lymphoma (2013) 1.39
Maternal peripheral blood level of IL-10 as a marker for inflammatory placental malaria. Malar J (2008) 1.37