Wall teichoic acid function, biosynthesis, and inhibition.

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Published in Chembiochem on January 04, 2010

Authors

Jonathan G Swoboda1, Jennifer Campbell, Timothy C Meredith, Suzanne Walker

Author Affiliations

1: Department of Microbiology and Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA.

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Single amino acid substitutions in either YhjD or MsbA confer viability to 3-deoxy-d-manno-oct-2-ulosonic acid-depleted Escherichia coli. Mol Microbiol (2007) 0.98

An antibiotic that inhibits a late step in wall teichoic acid biosynthesis induces the cell wall stress stimulon in Staphylococcus aureus. Antimicrob Agents Chemother (2012) 0.98

Decoupling catalytic activity from biological function of the ATPase that powers lipopolysaccharide transport. Proc Natl Acad Sci U S A (2014) 0.98

Substrate analogues to study cell-wall biosynthesis and its inhibition. Curr Opin Chem Biol (2002) 0.97

Teichoic acid biosynthesis as an antibiotic target. Curr Opin Microbiol (2013) 0.97

Detection of lipid-linked peptidoglycan precursors by exploiting an unexpected transpeptidase reaction. J Am Chem Soc (2014) 0.97

Isolation of transcription factor complexes by in vivo biotinylation tagging and direct binding to streptavidin beads. Methods Mol Biol (2006) 0.97

Development of improved inhibitors of wall teichoic acid biosynthesis with potent activity against Staphylococcus aureus. Bioorg Med Chem Lett (2010) 0.97

A strategy to discover inhibitors of O-linked glycosylation. J Am Chem Soc (2007) 0.96

Two distinct mechanisms for TIM barrel prenyltransferases in bacteria. J Am Chem Soc (2011) 0.96

Involvement of multiple developmental genes on chromosome 1p in lung tumorigenesis. Hum Mol Genet (2004) 0.95

A microfluidic platform for rapid, stress-induced antibiotic susceptibility testing of Staphylococcus aureus. Lab Chip (2012) 0.94

Haloduracin α binds the peptidoglycan precursor lipid II with 2:1 stoichiometry. J Am Chem Soc (2011) 0.94

Dissecting ramoplanin: mechanistic analysis of synthetic ramoplanin analogues as a guide to the design of improved antibiotics. J Am Chem Soc (2004) 0.94

The identification of protein-protein interactions of the nuclear pore complex of Saccharomyces cerevisiae using high throughput matrix-assisted laser desorption ionization time-of-flight tandem mass spectrometry. Mol Cell Proteomics (2002) 0.94

Semi-targeted plasma proteomics discovery workflow utilizing two-stage protein depletion and off-line LC-MALDI MS/MS. J Proteome Res (2010) 0.93

ABC transporters required for export of wall teichoic acids do not discriminate between different main chain polymers. ACS Chem Biol (2011) 0.93

High-frequency transposition for determining antibacterial mode of action. Nat Chem Biol (2011) 0.92

Synthesis of mono- and disaccharide analogs of moenomycin and lipid II for inhibition of transglycosylase activity of penicillin-binding protein 1b. Bioorg Med Chem (2004) 0.92

In vitro antimicrobial activity of wall teichoic acid biosynthesis inhibitors against Staphylococcus aureus isolates. Antimicrob Agents Chemother (2010) 0.92

Studying a cell division amidase using defined peptidoglycan substrates. J Am Chem Soc (2009) 0.91

Streptomyces ghanaensis pleiotropic regulatory gene wblA(gh) influences morphogenesis and moenomycin production. Biotechnol Lett (2011) 0.90

Pseudomonas aeruginosa directly shunts β-oxidation degradation intermediates into de novo fatty acid biosynthesis. J Bacteriol (2012) 0.90

Reconstitution and characterization of a new desosaminyl transferase, EryCIII, from the erythromycin biosynthetic pathway. J Am Chem Soc (2004) 0.90

WaaA of the hyperthermophilic bacterium Aquifex aeolicus is a monofunctional 3-deoxy-D-manno-oct-2-ulosonic acid transferase involved in lipopolysaccharide biosynthesis. J Biol Chem (2009) 0.90

Role of wall teichoic acids in Staphylococcus aureus endophthalmitis. Invest Ophthalmol Vis Sci (2011) 0.89