Published in Proc Natl Acad Sci U S A on March 01, 1991
Phylogenetic footprinting reveals a nuclear protein which binds to silencer sequences in the human gamma and epsilon globin genes. Mol Cell Biol (1992) 3.57
Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast. Proc Natl Acad Sci U S A (1993) 3.39
Alteration of N-terminal phosphoesterase signature motifs inactivates Saccharomyces cerevisiae Mre11. Genetics (1998) 2.32
Cdc42p GTPase is involved in controlling polarized cell growth in Schizosaccharomyces pombe. Mol Cell Biol (1994) 2.27
An evolutionarily conserved cyclin homolog from Drosophila rescues yeast deficient in G1 cyclins. Cell (1991) 2.19
Recombinant rat CBF-C, the third subunit of CBF/NFY, allows formation of a protein-DNA complex with CBF-A and CBF-B and with yeast HAP2 and HAP3. Proc Natl Acad Sci U S A (1995) 2.17
hCTR1: a human gene for copper uptake identified by complementation in yeast. Proc Natl Acad Sci U S A (1997) 2.04
Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae. Mol Cell Biol (1999) 1.99
Heme binds to a short sequence that serves a regulatory function in diverse proteins. EMBO J (1995) 1.98
The fission yeast rad22 gene, having a function in mating-type switching and repair of DNA damages, encodes a protein homolog to Rad52 of Saccharomyces cerevisiae. Nucleic Acids Res (1993) 1.94
Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription. Proc Natl Acad Sci U S A (1994) 1.91
Xenopus NF-Y pre-sets chromatin to potentiate p300 and acetylation-responsive transcription from the Xenopus hsp70 promoter in vivo. EMBO J (1998) 1.85
Interaction of HapX with the CCAAT-binding complex--a novel mechanism of gene regulation by iron. EMBO J (2007) 1.83
Mutations in yeast HAP2/HAP3 define a hybrid CCAAT box binding domain. EMBO J (1993) 1.72
Genetic dissection of the signaling domain of a mammalian steroid receptor in yeast. Mol Biol Cell (1992) 1.64
Evolutionary variation of the CCAAT-binding transcription factor NF-Y. Nucleic Acids Res (1992) 1.60
Multiple genes encoding the conserved CCAAT-box transcription factor complex are expressed in Arabidopsis. Plant Physiol (1998) 1.59
Roles of a fimbrin and an alpha-actinin-like protein in fission yeast cell polarization and cytokinesis. Mol Biol Cell (2001) 1.55
Yeast SUB1 is a suppressor of TFIIB mutations and has homology to the human co-activator PC4. EMBO J (1996) 1.49
Three classes of mutations in the A subunit of the CCAAT-binding factor CBF delineate functional domains involved in the three-step assembly of the CBF-DNA complex. Mol Cell Biol (1996) 1.49
DNA ligase I mediates essential functions in mammalian cells. Mol Cell Biol (1995) 1.47
Four subunits that are shared by the three classes of RNA polymerase are functionally interchangeable between Homo sapiens and Saccharomyces cerevisiae. Mol Cell Biol (1995) 1.43
Recombinational telomere elongation promoted by DNA circles. Mol Cell Biol (2002) 1.43
Modulation of Saccharomyces cerevisiae DNA double-strand break repair by SRS2 and RAD51. Genetics (1995) 1.38
Cloning of the Schizosaccharomyces pombe gene encoding diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) asymmetrical hydrolase: sequence similarity with the histidine triad (HIT) protein family. Biochem J (1995) 1.38
The gene YALI0E20207g from Yarrowia lipolytica encodes an N-acetylglucosamine kinase implicated in the regulated expression of the genes from the N-acetylglucosamine assimilatory pathway. PLoS One (2015) 1.37
A novel suppressor of ras1 in fission yeast, byr4, is a dosage-dependent inhibitor of cytokinesis. J Cell Biol (1996) 1.36
A yeast expression system for human galactose-1-phosphate uridylyltransferase. Proc Natl Acad Sci U S A (1993) 1.35
Hyperosmotic stress induces the rapid phosphorylation of a soybean phosphatidylinositol transfer protein homolog through activation of the protein kinases SPK1 and SPK2. Plant Cell (2001) 1.32
The Saccharomyces cerevisiae Hap5p homolog from fission yeast reveals two conserved domains that are essential for assembly of heterotetrameric CCAAT-binding factor. Mol Cell Biol (1997) 1.30
A human mitochondrial GTP binding protein related to tRNA modification may modulate phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation. Mol Cell Biol (2002) 1.30
Human ARF4 expression rescues sec7 mutant yeast cells. Mol Cell Biol (1996) 1.27
The Schizosaccharomyces pombe spo20(+) gene encoding a homologue of Saccharomyces cerevisiae Sec14 plays an important role in forespore membrane formation. Mol Biol Cell (2001) 1.26
An oligopeptide transporter gene family in Arabidopsis. Plant Physiol (2002) 1.25
Schizosaccharomyces pombe pfh1+ encodes an essential 5' to 3' DNA helicase that is a member of the PIF1 subfamily of DNA helicases. Mol Biol Cell (2002) 1.23
Yeast coactivator MBF1 mediates GCN4-dependent transcriptional activation. Mol Cell Biol (1998) 1.21
Subunit interaction in the CCAAT-binding heteromeric complex is mediated by a very short alpha-helix in HAP2. Proc Natl Acad Sci U S A (1994) 1.21
Suppression mechanisms of COX assembly defects in yeast and human: insights into the COX assembly process. Biochim Biophys Acta (2008) 1.20
The fission yeast prp4+ gene involved in pre-mRNA splicing codes for a predicted serine/threonine kinase and is essential for growth. Nucleic Acids Res (1993) 1.15
ScOPT1 and AtOPT4 function as proton-coupled oligopeptide transporters with broad but distinct substrate specificities. Biochem J (2006) 1.14
Roles of Oxa1-related inner-membrane translocases in assembly of respiratory chain complexes. Biochim Biophys Acta (2008) 1.13
The AAPT1 gene of soybean complements a cholinephosphotransferase-deficient mutant of yeast. Plant Cell (1994) 1.11
Mutations in MTO2 related to tRNA modification impair mitochondrial gene expression and protein synthesis in the presence of a paromomycin resistance mutation in mitochondrial 15 S rRNA. J Biol Chem (2005) 1.09
The CCAAT-binding complex coordinates the oxidative stress response in eukaryotes. Nucleic Acids Res (2009) 1.08
Isolation of a human cDNA for heme A:farnesyltransferase by functional complementation of a yeast cox10 mutant. Proc Natl Acad Sci U S A (1994) 1.06
Expression analyses of Arabidopsis oligopeptide transporters during seed germination, vegetative growth and reproduction. Planta (2005) 1.06
A wild-type DNA ligase I gene is expressed in Bloom's syndrome cells. Proc Natl Acad Sci U S A (1991) 1.04
Functional characterization of phospholipid N-methyltransferases from Arabidopsis and soybean. J Biol Chem (2009) 1.03
Variations in Mre11/Rad50/Nbs1 status and DNA damage-induced S-phase arrest in the cell lines of the NCI60 panel. BMC Cancer (2011) 1.00
H1TF2A, the large subunit of a heterodimeric, glutamine-rich CCAAT-binding transcription factor involved in histone H1 cell cycle regulation. Mol Cell Biol (1994) 0.94
Triple gene block protein interactions involved in movement of Barley stripe mosaic virus. J Virol (2008) 0.93
Insights into Alternanthera mosaic virus TGB3 Functions: Interactions with Nicotiana benthamiana PsbO Correlate with Chloroplast Vesiculation and Veinal Necrosis Caused by TGB3 Over-Expression. Front Plant Sci (2013) 0.90
Changes of telomere length cause reciprocal changes in the lifespan of mother cells in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1997) 0.90
The Neurospora aab-1 gene encodes a CCAAT binding protein homologous to yeast HAP5. Genetics (1998) 0.87
Expression and functional analysis of NUCLEAR FACTOR-Y, subunit B genes in barley. Planta (2011) 0.87
Isolation of a gene encoding a chaperonin-like protein by complementation of yeast amino acid transport mutants with human cDNA. Proc Natl Acad Sci U S A (1992) 0.85
A streamlined process to phenotypically profile heterologous cDNAs in parallel using yeast cell-based assays. Genome Res (2001) 0.85
Divergent subunit interactions among fungal mRNA 5'-capping machineries. Eukaryot Cell (2002) 0.84
Identification and characterization of NF-Y transcription factor families in Canola (Brassica napus L.). Planta (2013) 0.84
The gluconeogenic enzyme fructose-1,6-bisphosphatase is dispensable for growth of the yeast Yarrowia lipolytica in gluconeogenic substrates. Eukaryot Cell (2008) 0.83
Characterization of soybean choline kinase cDNAs and their expression in yeast and Escherichia coli. Plant Physiol (1996) 0.82
Yarrowia lipolytica mutants devoid of pyruvate carboxylase activity show an unusual growth phenotype. Eukaryot Cell (2005) 0.82
NFY interacts with the promoter region of two genes involved in the rat peroxisomal fatty acid beta-oxidation: the multifunctional protein type 1 and the 3-ketoacyl-CoA B thiolase. Lipids Health Dis (2004) 0.81
Disruption of Yarrowia lipolytica TPS1 gene encoding trehalose-6-P synthase does not affect growth in glucose but impairs growth at high temperature. PLoS One (2011) 0.78
Isolation and characterization of cDNAs encoding the sea urchin (Strongylocentrotus purpuratus) homologue of the CCAAT binding protein NF-Y A subunit. Nucleic Acids Res (1993) 0.78
Mechanistic study on the nuclear modifier gene MSS1 mutation suppressing neomycin sensitivity of the mitochondrial 15S rRNA C1477G mutation in Saccharomyces cerevisiae. PLoS One (2014) 0.78
Disruption of PMR1, encoding a Ca2+-ATPase homolog in Yarrowia lipolytica, affects secretion and processing of homologous and heterologous proteins. J Bacteriol (1998) 0.77
New nucleotide sequence data on the EMBL File Server. Nucleic Acids Res (1991) 0.75
Long telomeres produced by telomerase-resistant recombination are established from a single source and are subject to extreme sequence scrambling. PLoS Genet (2012) 0.75
A stress response related to the carbon source and the absence of KlHAP2 in Kluyveromyces lactis. J Ind Microbiol Biotechnol (2010) 0.75
High efficiency transformation of E. coli by high voltage electroporation. Nucleic Acids Res (1988) 34.78
Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell (1988) 12.68
Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system. Proc Natl Acad Sci U S A (1987) 10.38
Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1. Science (1987) 10.25
Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element. Cell (1988) 9.34
Isolation of a recombinant copy of the gene encoding C/EBP. Genes Dev (1988) 9.11
Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2. Nature (1987) 8.87
Weight matrix descriptions of four eukaryotic RNA polymerase II promoter elements derived from 502 unrelated promoter sequences. J Mol Biol (1990) 8.75
A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs. Nature (1988) 6.54
A multiplicity of CCAAT box-binding proteins. Cell (1987) 6.37
Human CCAAT-binding proteins have heterologous subunits. Cell (1988) 5.81
Expression of genes in yeast using the ADCI promoter. Methods Enzymol (1983) 4.94
Identification and characterization of HAP4: a third component of the CCAAT-bound HAP2/HAP3 heteromer. Genes Dev (1989) 4.43
A protein involved in minichromosome maintenance in yeast binds a transcriptional enhancer conserved in eukaryotes. Genes Dev (1989) 3.41
Striking conservation of TFIID in Schizosaccharomyces pombe and Saccharomyces cerevisiae. Nature (1990) 3.03
Several distinct "CCAAT" box binding proteins coexist in eukaryotic cells. Proc Natl Acad Sci U S A (1988) 3.01
The yeast transcription activator PRTF, a homolog of the mammalian serum response factor, is encoded by the MCM1 gene. Genes Dev (1989) 2.89
A yeast and a human CCAAT-binding protein have heterologous subunits that are functionally interchangeable. Cell (1988) 2.84
The JUN oncoprotein, a vertebrate transcription factor, activates transcription in yeast. Nature (1988) 2.77
Yeast HAP2 and HAP3 activators both bind to the CYC1 upstream activation site, UAS2, in an interdependent manner. Cell (1987) 2.73
Co-evolution from yeast to mouse: cDNA cloning of the two NF-Y (CP-1/CBF) subunits. EMBO J (1990) 2.49
The HAP2 subunit of yeast CCAAT transcriptional activator contains adjacent domains for subunit association and DNA recognition: model for the HAP2/3/4 complex. Genes Dev (1990) 2.37
Yeast repressor alpha 2 binds to its operator cooperatively with yeast protein Mcm1. Mol Cell Biol (1989) 2.33
Isolation and characterization of a mammalian gene encoding a high-affinity cAMP phosphodiesterase. Proc Natl Acad Sci U S A (1989) 2.31
Cloning of three human multifunctional de novo purine biosynthetic genes by functional complementation of yeast mutations. Proc Natl Acad Sci U S A (1990) 2.16
The cell type-specific octamer transcription factor OTF-2 has two domains required for the activation of transcription. EMBO J (1990) 2.01
The HAP3 regulatory locus of Saccharomyces cerevisiae encodes divergent overlapping transcripts. Mol Cell Biol (1988) 1.87
Communication between mitochondria and the nucleus in regulation of cytochrome genes in the yeast Saccharomyces cerevisiae. Annu Rev Cell Biol (1989) 1.83
Yeast HAP2 and HAP3: transcriptional activators in a heteromeric complex. Science (1988) 1.79
The B subunit of a rat heteromeric CCAAT-binding transcription factor shows a striking sequence identity with the yeast Hap2 transcription factor. Proc Natl Acad Sci U S A (1990) 1.63
Constitutive expression of the yeast HEM1 gene is actually a composite of activation and repression. Proc Natl Acad Sci U S A (1987) 1.45
The presence of a DNA binding complex correlates with E beta class II MHC gene expression. EMBO J (1990) 0.96
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature (2000) 20.54
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell (2001) 15.97
Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell (2001) 15.05
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature (2001) 14.44
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev (1999) 14.43
Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast. Methods Enzymol (1983) 12.99
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science (2000) 12.98
A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site. Proc Natl Acad Sci U S A (1982) 11.42
Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site. Cell (1983) 10.52
Fusion of Escherichia coli lacZ to the cytochrome c gene of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1981) 9.45
Five intermediate complexes in transcription initiation by RNA polymerase II. Cell (1989) 9.22
Extrachromosomal rDNA circles--a cause of aging in yeast. Cell (1997) 8.68
High-efficiency transformation of yeast by electroporation. Methods Enzymol (1991) 7.99
Distinctly regulated tandem upstream activation sites mediate catabolite repression of the CYC1 gene of S. cerevisiae. Cell (1984) 6.86
Improved methods for maximizing expression of a cloned gene: a bacterium that synthesizes rabbit beta-globin. Cell (1980) 6.20
Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains. Cell (1992) 5.14
Upstream activation sites of the CYC1 gene of Saccharomyces cerevisiae are active when inverted but not when placed downstream of the "TATA box". Proc Natl Acad Sci U S A (1984) 4.88
Yeast promoters: positive and negative elements. Cell (1984) 4.87
Each of three "TATA elements" specifies a subset of the transcription initiation sites at the CYC-1 promoter of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1985) 4.69
Identification and characterization of HAP4: a third component of the CCAAT-bound HAP2/HAP3 heteromer. Genes Dev (1989) 4.43
Yeast HAP1 activator binds to two upstream activation sites of different sequence. Cell (1987) 4.37
Function of a yeast TATA element-binding protein in a mammalian transcription system. Nature (1988) 3.91
MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks. Cell (1999) 3.62
Functional dissection and sequence of yeast HAP1 activator. Cell (1989) 3.56
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants. Science (1997) 3.48
Elimination of replication block protein Fob1 extends the life span of yeast mother cells. Mol Cell (1999) 3.46
Yeast HAP1 activator competes with the factor RC2 for binding to the upstream activation site UAS1 of the CYC1 gene. Cell (1987) 3.46
Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae. Cell (1997) 3.44
Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae. Cell (1995) 3.37
Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: evidence for transcriptional adaptors. Cell (1990) 3.31
Isolation of the gene encoding the yeast TATA binding protein TFIID: a gene identical to the SPT15 suppressor of Ty element insertions. Cell (1989) 3.18
Yeast TATA-binding protein TFIID binds to TATA elements with both consensus and nonconsensus DNA sequences. Proc Natl Acad Sci U S A (1989) 3.18
Molecular biology of aging. Cell (1999) 3.08
Striking conservation of TFIID in Schizosaccharomyces pombe and Saccharomyces cerevisiae. Nature (1990) 3.03
Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors. EMBO J (1994) 3.00
A yeast and a human CCAAT-binding protein have heterologous subunits that are functionally interchangeable. Cell (1988) 2.84
Structure of the malB region in Escherichia coli K12. II. Genetic map of the malE,F,G operon. Mol Gen Genet (1979) 2.83
Yeast HAP2 and HAP3 activators both bind to the CYC1 upstream activation site, UAS2, in an interdependent manner. Cell (1987) 2.73
Daughter cells of Saccharomyces cerevisiae from old mothers display a reduced life span. J Cell Biol (1994) 2.71
Loss of transcriptional silencing causes sterility in old mother cells of S. cerevisiae. Cell (1996) 2.53
Open reading frame cloning: identification, cloning, and expression of open reading frame DNA. Proc Natl Acad Sci U S A (1982) 2.39
The HAP2 subunit of yeast CCAAT transcriptional activator contains adjacent domains for subunit association and DNA recognition: model for the HAP2/3/4 complex. Genes Dev (1990) 2.37
SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production. Oncogene (2011) 2.35
Association of the Bloom syndrome protein with topoisomerase IIIalpha in somatic and meiotic cells. Cancer Res (2000) 2.13
Export of unprocessed precursor maltose-binding protein to the periplasm of Escherichia coli cells. J Bacteriol (1987) 2.12
Mutational analysis of a yeast transcriptional terminator. Proc Natl Acad Sci U S A (1989) 2.12
ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complex. Mol Cell Biol (1995) 2.11
Cloning of yeast HAP5: a novel subunit of a heterotrimeric complex required for CCAAT binding. Genes Dev (1995) 2.00
ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2. Mol Cell Biol (1993) 2.00
Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae. Mol Cell Biol (1999) 1.99
The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase. EMBO J (2001) 1.99
Cloning and molecular analysis of the HAP2 locus: a global regulator of respiratory genes in Saccharomyces cerevisiae. Mol Cell Biol (1985) 1.98
Heme binds to a short sequence that serves a regulatory function in diverse proteins. EMBO J (1995) 1.98
Mutational analysis of upstream activation sequence 2 of the CYC1 gene of Saccharomyces cerevisiae: a HAP2-HAP3-responsive site. Mol Cell Biol (1988) 1.95
Nucleolar localization of the Werner syndrome protein in human cells. Proc Natl Acad Sci U S A (1998) 1.92
Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription. Proc Natl Acad Sci U S A (1994) 1.91
The HAP3 regulatory locus of Saccharomyces cerevisiae encodes divergent overlapping transcripts. Mol Cell Biol (1988) 1.87
Evidence for BLM and Topoisomerase IIIalpha interaction in genomic stability. Hum Mol Genet (2001) 1.85
Expression of the human fibroblast interferon gene in Escherichia coli. Proc Natl Acad Sci U S A (1980) 1.84
Communication between mitochondria and the nucleus in regulation of cytochrome genes in the yeast Saccharomyces cerevisiae. Annu Rev Cell Biol (1989) 1.83
Saccharomyces cerevisiae contains two functional citrate synthase genes. Mol Cell Biol (1986) 1.82
In vitro construction and characterization of phoA-lacZ gene fusions in Escherichia coli. J Bacteriol (1983) 1.82
Yeast HAP2 and HAP3: transcriptional activators in a heteromeric complex. Science (1988) 1.79
Passage through stationary phase advances replicative aging in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1999) 1.76
Genetic selection for genes encoding sequence-specific DNA-binding proteins. Proc Natl Acad Sci U S A (1989) 1.75
ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3. Mol Cell Biol (1997) 1.74
ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription. Mol Cell Biol (1996) 1.74
Mutations in yeast HAP2/HAP3 define a hybrid CCAAT box binding domain. EMBO J (1993) 1.72
Transcription by RNA polymerase II induces changes of DNA topology in yeast. Genes Dev (1988) 1.69
A therapeutic role for sirtuins in diseases of aging? Trends Biochem Sci (2007) 1.65
Nuclear structure in normal and Bloom syndrome cells. Proc Natl Acad Sci U S A (2000) 1.60
The short life span of Saccharomyces cerevisiae sgs1 and srs2 mutants is a composite of normal aging processes and mitotic arrest due to defective recombination. Genetics (2001) 1.59
Isolation, sequence, and regulation by oxygen of the yeast HEM13 gene coding for coproporphyrinogen oxidase. J Biol Chem (1988) 1.56
The yeast activator HAP1--a GAL4 family member--binds DNA in a directly repeated orientation. Genes Dev (1994) 1.56
Vectors for expression of cloned genes in yeast: regulation, overproduction, and underproduction. Methods Enzymol (1991) 1.55
Aging in Saccharomyces cerevisiae. Annu Rev Microbiol (1998) 1.52
Structure of a HAP1-DNA complex reveals dramatically asymmetric DNA binding by a homodimeric protein. Nat Struct Biol (1999) 1.51
Yeast SUB1 is a suppressor of TFIIB mutations and has homology to the human co-activator PC4. EMBO J (1996) 1.49
Mutations in the WRN gene in mice accelerate mortality in a p53-null background. Mol Cell Biol (2000) 1.48
Increased dosage of a transcriptional activator gene enhances iron-limited growth of Saccharomyces cerevisiae. J Gen Microbiol (1992) 1.46
Constitutive expression of the yeast HEM1 gene is actually a composite of activation and repression. Proc Natl Acad Sci U S A (1987) 1.45
The nine amino-terminal residues of delta-aminolevulinate synthase direct beta-galactosidase into the mitochondrial matrix. Mol Cell Biol (1986) 1.45
Molecular mechanisms of yeast aging. Trends Biochem Sci (1998) 1.42
Sir2: an NAD-dependent histone deacetylase that connects chromatin silencing, metabolism, and aging. Cold Spring Harb Symp Quant Biol (2000) 1.41
Mutant lambda phage repressor with a specific defect in its positive control function. Proc Natl Acad Sci U S A (1982) 1.39
Molecular links between aging and adipose tissue. Int J Obes (Lond) (2005) 1.37
Expression and functional significance of alternatively spliced CS1 fibronectin in rheumatoid arthritis microvasculature. J Clin Invest (1994) 1.34
The overproducing CYP1 and the underproducing hap1 mutations are alleles of the same gene which regulates in trans the expression of the structural genes encoding iso-cytochromes c. Curr Genet (1986) 1.33
Organization of the regulatory region of the yeast CYC7 gene: multiple factors are involved in regulation. Mol Cell Biol (1987) 1.33
Mutations that alter transcriptional activation but not DNA binding in the zinc finger of yeast activator HAPI. Nature (1989) 1.31
The Saccharomyces cerevisiae Hap5p homolog from fission yeast reveals two conserved domains that are essential for assembly of heterotetrameric CCAAT-binding factor. Mol Cell Biol (1997) 1.30
Identification of a novel simian parvovirus in cynomolgus monkeys with severe anemia. A paradigm of human B19 parvovirus infection. J Clin Invest (1994) 1.26
Identification of a yeast protein homologous in function to the mammalian general transcription factor, TFIIA. EMBO J (1989) 1.25
Analysis of mutational alterations in the hydrophilic segment of the maltose-binding protein signal peptide. J Bacteriol (1989) 1.25
HAP1 positive control mutants specific for one of two binding sites. Genes Dev (1992) 1.24
A common muscarinic pathway for diapause recovery in the distantly related nematode species Caenorhabditis elegans and Ancylostoma caninum. Proc Natl Acad Sci U S A (2000) 1.24
Subunit interaction in the CCAAT-binding heteromeric complex is mediated by a very short alpha-helix in HAP2. Proc Natl Acad Sci U S A (1994) 1.21
Metabolic changes in Saccharomyces cerevisiae strains lacking citrate synthases. J Biol Chem (1988) 1.21
Nijmegen breakage syndrome disease protein and MRE11 at PML nuclear bodies and meiotic telomeres. Cancer Res (2000) 1.20