Published in Circ Cardiovasc Genet on December 09, 2008
The gene expression profile of patients with new-onset heart failure reveals important gender-specific differences. Eur Heart J (2009) 1.73
Gene expression profiling in sepsis: timing, tissue, and translational considerations. Trends Mol Med (2014) 1.25
Modulation of sarcoplasmic reticulum Ca(2+) cycling in systolic and diastolic heart failure associated with aging. Heart Fail Rev (2010) 0.98
Sprouty1 inhibits angiogenesis in association with up-regulation of p21 and p27. Mol Cell Biochem (2010) 0.88
Age-dependent sex effects on outcomes after pediatric cardiac surgery. J Am Heart Assoc (2014) 0.81
Changes in expression of proteoglycan core proteins and heparan sulfate enzymes in the developing and adult murine aorta. J Cardiovasc Transl Res (2011) 0.81
Identification of differentially expressed transcripts and pathways in blood one week and six months following implant of left ventricular assist devices. PLoS One (2013) 0.79
Large Scale Gene Expression Meta-Analysis Reveals Tissue-Specific, Sex-Biased Gene Expression in Humans. Front Genet (2016) 0.77
Sex-dimorphism in cardiac nutrigenomics: effect of trans fat and/or monosodium glutamate consumption. BMC Genomics (2011) 0.77
Best Practice BioBanking of Human Heart Tissue. Biophys Rev (2015) 0.75
Interleukin-6 (IL-6) rs1800796 and cyclin dependent kinase inhibitor (CDKN2A/CDKN2B) rs2383207 are associated with ischemic stroke in indigenous West African Men. J Neurol Sci (2017) 0.75
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A (2005) 167.46
Bioconductor: open software development for computational biology and bioinformatics. Genome Biol (2004) 143.19
DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol (2003) 84.79
TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes. Nucleic Acids Res (2006) 22.20
More powerful procedures for multiple significance testing. Stat Med (1990) 17.12
Identifying differentially expressed genes using false discovery rate controlling procedures. Bioinformatics (2003) 16.60
Using GOstats to test gene lists for GO term association. Bioinformatics (2006) 12.58
Long-term trends in the incidence of and survival with heart failure. N Engl J Med (2002) 10.37
Lifetime risk of developing coronary heart disease. Lancet (1999) 7.54
Tissue-specific expression and regulation of sexually dimorphic genes in mice. Genome Res (2006) 6.45
The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases. Cell (2007) 6.04
Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases. Proc Natl Acad Sci U S A (2007) 4.20
Comparison of relative mRNA quantification models and the impact of RNA integrity in quantitative real-time RT-PCR. Biotechnol Lett (2006) 3.53
JMJD6 is a histone arginine demethylase. Science (2007) 3.48
cis-Acting sequences that mediate induction of beta-myosin heavy chain gene expression during left ventricular hypertrophy due to aortic constriction. Circulation (1997) 2.54
Mathematical formulae for the prediction of the residual beta cell function during the first two years of disease in children and adolescents with insulin-dependent diabetes mellitus. Med Hypotheses (1995) 2.53
Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulation. Nat Cell Biol (2007) 2.50
The MEF2D transcription factor mediates stress-dependent cardiac remodeling in mice. J Clin Invest (2008) 2.24
Genomic profiling of the human heart before and after mechanical support with a ventricular assist device reveals alterations in vascular signaling networks. Physiol Genomics (2004) 2.17
Roles of jumonji and jumonji family genes in chromatin regulation and development. Dev Dyn (2006) 2.08
Cardiac-specific ablation of G-protein receptor kinase 2 redefines its roles in heart development and beta-adrenergic signaling. Circ Res (2006) 2.08
Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function. Proc Natl Acad Sci U S A (1996) 2.06
Transcriptional genomics associates FOX transcription factors with human heart failure. Circulation (2006) 2.00
Identification of transcription factor binding sites in the human genome sequence. Mamm Genome (2002) 2.00
Basal myosin light chain phosphorylation is a determinant of Ca2+ sensitivity of force and activation dependence of the kinetics of myocardial force development. Am J Physiol Heart Circ Physiol (2004) 1.93
Gender differences in advanced heart failure: insights from the BEST study. J Am Coll Cardiol (2003) 1.91
Metoprolol CR/XL in female patients with heart failure: analysis of the experience in Metoprolol Extended-Release Randomized Intervention Trial in Heart Failure (MERIT-HF). Circulation (2002) 1.74
Cardiac sodium channel gene variants and sudden cardiac death in women. Circulation (2007) 1.67
Mixed messages: transcription patterns in failing and recovering human myocardium. Circ Res (2005) 1.61
Female predominance and transmission distortion in the long-QT syndrome. N Engl J Med (2006) 1.55
Cardiovascular roles of nitric oxide: a review of insights from nitric oxide synthase gene disrupted mice. Cardiovasc Res (2008) 1.53
Gender differences in survival in advanced heart failure. Insights from the FIRST study. Circulation (1999) 1.36
Gender differences in molecular remodeling in pressure overload hypertrophy. J Am Coll Cardiol (1999) 1.32
Sexually dimorphic gene expression in the heart of mice and men. J Mol Med (Berl) (2007) 1.30
Hypertrophic remodeling: gender differences in the early response to left ventricular pressure overload. J Am Coll Cardiol (1998) 1.28
Sex differences in the prognosis of congestive heart failure: results from the Cardiac Insufficiency Bisoprolol Study (CIBIS II). Circulation (2001) 1.06
Tropomyosin 3 expression leads to hypercontractility and attenuates myofilament length-dependent Ca(2+) activation. Am J Physiol Heart Circ Physiol (2002) 1.03
Sex- and age-dependent human transcriptome variability: implications for chronic heart failure. Proc Natl Acad Sci U S A (2003) 0.96
Physiological and molecular mechanisms governing sexual dimorphism of kidney, cardiac, and vascular function. Am J Physiol Regul Integr Comp Physiol (2006) 0.93
Hypertensive cardiac remodeling in males and females: from the bench to the bedside. Hypertension (2007) 0.86
Dysregulation of connexins and inactivation of NFATc1 in the cardiovascular system of Nkx2-5 null mutants. J Mol Cell Cardiol (2005) 0.85
The gender differences in the relaxation to levosimendan of human internal mammary artery. Cardiovasc Drugs Ther (2007) 0.83
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus. Nature (2010) 12.07
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease. Nat Genet (2008) 9.52
Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. PLoS One (2008) 7.16
Evaluation study of congestive heart failure and pulmonary artery catheterization effectiveness: the ESCAPE trial. JAMA (2005) 6.10
Whole-genome shotgun assembly and comparison of human genome assemblies. Proc Natl Acad Sci U S A (2004) 6.08
Timing of antiretroviral therapy after diagnosis of cryptococcal meningitis. N Engl J Med (2014) 4.91
Outcomes of left ventricular assist device implantation as destination therapy in the post-REMATCH era: implications for patient selection. Circulation (2007) 4.67
Gene-expression profiling for rejection surveillance after cardiac transplantation. N Engl J Med (2010) 4.31
A transposon-based genetic screen in mice identifies genes altered in colorectal cancer. Science (2009) 4.16
Extended mechanical circulatory support with a continuous-flow rotary left ventricular assist device. J Am Coll Cardiol (2009) 4.03
Clinical management of continuous-flow left ventricular assist devices in advanced heart failure. J Heart Lung Transplant (2010) 4.00
Genome-wide analysis of retroviral DNA integration. Nat Rev Microbiol (2005) 3.98
Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms. Nature (2002) 3.92
Retroviral DNA integration: viral and cellular determinants of target-site selection. PLoS Pathog (2006) 3.67
Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies. N Engl J Med (2016) 3.40
Use of an intrapericardial, continuous-flow, centrifugal pump in patients awaiting heart transplantation. Circulation (2012) 3.24
Selection of target sites for mobile DNA integration in the human genome. PLoS Comput Biol (2006) 3.21
Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia. Blood (2008) 3.18
Adult mouse epicardium modulates myocardial injury by secreting paracrine factors. J Clin Invest (2011) 2.99
Clinical features and serum biomarkers in HIV immune reconstitution inflammatory syndrome after cryptococcal meningitis: a prospective cohort study. PLoS Med (2010) 2.94
Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial. J Card Fail (2009) 2.89
Cellular basis of abnormal calcium transients of failing human ventricular myocytes. Circ Res (2003) 2.86
The 2013 International Society for Heart and Lung Transplantation Guidelines for mechanical circulatory support: executive summary. J Heart Lung Transplant (2013) 2.71
Reciprocal regulation of myocardial microRNAs and messenger RNA in human cardiomyopathy and reversal of the microRNA signature by biomechanical support. Circulation (2009) 2.70
L-type Ca2+ channel density and regulation are altered in failing human ventricular myocytes and recover after support with mechanical assist devices. Circ Res (2002) 2.62
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet (2012) 2.53
A subpopulation of human peripheral blood NK cells that lacks inhibitory receptors for self-MHC is developmentally immature. Blood (2007) 2.39
Cardiac improvement during mechanical circulatory support: a prospective multicenter study of the LVAD Working Group. Circulation (2007) 2.34
Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis. J Clin Invest (2010) 2.32
Animal models of heart failure: a scientific statement from the American Heart Association. Circ Res (2012) 2.31
Right ventricular failure in patients with the HeartMate II continuous-flow left ventricular assist device: incidence, risk factors, and effect on outcomes. J Thorac Cardiovasc Surg (2010) 2.29
Elevated myocardial and lymphocyte GRK2 expression and activity in human heart failure. Eur Heart J (2005) 2.29
Genomic profiling of the human heart before and after mechanical support with a ventricular assist device reveals alterations in vascular signaling networks. Physiol Genomics (2004) 2.17
BET bromodomains mediate transcriptional pause release in heart failure. Cell (2013) 2.17
Recruitment of dynein to the Jurkat immunological synapse. Proc Natl Acad Sci U S A (2006) 2.15
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet (2010) 2.15
Interaction between loop diuretic-associated mortality and blood urea nitrogen concentration in chronic heart failure. J Am Coll Cardiol (2011) 2.09
Class IV semaphorins promote angiogenesis by stimulating Rho-initiated pathways through plexin-B. Cancer Res (2004) 2.05
Transcriptional genomics associates FOX transcription factors with human heart failure. Circulation (2006) 2.00
Identification of transcription factor binding sites in the human genome sequence. Mamm Genome (2002) 2.00
High-sensitivity ST2 for prediction of adverse outcomes in chronic heart failure. Circ Heart Fail (2010) 1.96
A microfabricated platform to measure and manipulate the mechanics of engineered cardiac microtissues. Tissue Eng Part A (2012) 1.95
DNA sequence and analysis of human chromosome 8. Nature (2006) 1.91
Is depressed myocyte contractility centrally involved in heart failure? Circ Res (2003) 1.88
Ventricular-arterial coupling, remodeling, and prognosis in chronic heart failure. J Am Coll Cardiol (2013) 1.86
Left ventricular assist device therapy improves utilization of donor hearts. J Am Coll Cardiol (2002) 1.85
Strong synaptic transmission impact by copy number variations in schizophrenia. Proc Natl Acad Sci U S A (2010) 1.85
A comparative study of discriminating human heart failure etiology using gene expression profiles. BMC Bioinformatics (2005) 1.85
Renal and hepatic function improve in advanced heart failure patients during continuous-flow support with the HeartMate II left ventricular assist device. Circulation (2009) 1.84
Abnormal frequency-dependent responses represent the pathophysiologic signature of contractile failure in human myocardium. J Mol Cell Cardiol (2004) 1.81
Tissue-specific alternative splicing of TCF7L2. Hum Mol Genet (2009) 1.80
Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes. Genome Biol (2007) 1.79
Molecular signature of recovery following combination left ventricular assist device (LVAD) support and pharmacologic therapy. Eur Heart J (2006) 1.78
Impact of center volume on outcomes of left ventricular assist device implantation as destination therapy: analysis of the Thoratec HeartMate Registry, 1998 to 2005. Circ Heart Fail (2009) 1.77
KIR reconstitution is altered by T cells in the graft and correlates with clinical outcomes after unrelated donor transplantation. Blood (2005) 1.74
Recommendations for successful training on methods of delivery of biologics for cardiac regeneration: a report of the International Society for Cardiovascular Translational Research. JACC Cardiovasc Interv (2010) 1.74
A role for the beta-catenin/T-cell factor signaling cascade in vascular remodeling. Circ Res (2002) 1.72
The cost of medical management in advanced heart failure during the final two years of life. J Card Fail (2008) 1.71
Clinical characteristics and outcomes of patients with improvement in renal function during the treatment of decompensated heart failure. J Card Fail (2011) 1.70
The adult human heart as a source for stem cells: repair strategies with embryonic-like progenitor cells. Nat Clin Pract Cardiovasc Med (2007) 1.70
Divergent mitochondrial biogenesis responses in human cardiomyopathy. Circulation (2013) 1.69
Clinical, molecular, and genomic changes in response to a left ventricular assist device. J Am Coll Cardiol (2011) 1.69
Reciprocal transcriptional regulation of metabolic and signaling pathways correlates with disease severity in heart failure. Circ Cardiovasc Genet (2011) 1.68
Increased cardiac myocyte progenitors in failing human hearts. Circulation (2008) 1.68
Genomic analysis of sleep deprivation reveals translational regulation in the hippocampus. Physiol Genomics (2012) 1.64
Sex differences in obesity-related changes in left ventricular morphology: the Strong Heart Study. J Hypertens (2011) 1.61
Simultaneous assessment of unprocessed ProBNP1-108 in addition to processed BNP32 improves identification of high-risk ambulatory patients with heart failure. Circ Heart Fail (2010) 1.60
Multiple biomarkers for risk prediction in chronic heart failure. Circ Heart Fail (2012) 1.57
Infection in permanent circulatory support: experience from the REMATCH trial. J Heart Lung Transplant (2004) 1.56
Improved survival of patients with end-stage heart failure listed for heart transplantation: analysis of organ procurement and transplantation network/U.S. United Network of Organ Sharing data, 1990 to 2005. J Am Coll Cardiol (2007) 1.56
Detection of cardiac allograft rejection and response to immunosuppressive therapy with peripheral blood gene expression. Circulation (2004) 1.56
Neuregulin-1 beta is associated with disease severity and adverse outcomes in chronic heart failure. Circulation (2009) 1.55
Risk assessment for continuous flow left ventricular assist devices: does the destination therapy risk score work? An analysis of over 1,000 patients. J Am Coll Cardiol (2012) 1.55
Oxidative stress regulates left ventricular PDE5 expression in the failing heart. Circulation (2010) 1.54
The role of cerebral hyperperfusion in postoperative neurologic dysfunction after left ventricular assist device implantation for end-stage heart failure. J Thorac Cardiovasc Surg (2009) 1.52
Homo- and hetero-oligomerization of PDZ-RhoGEF, LARG and p115RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential. Oncogene (2004) 1.52
Analysis of the DNA sequence and duplication history of human chromosome 15. Nature (2006) 1.50
Ubiquitin proteasome dysfunction in human hypertrophic and dilated cardiomyopathies. Circulation (2010) 1.49
Structure-based prediction of insertion-site preferences of transposons into chromosomes. Nucleic Acids Res (2006) 1.48
Identification of a gene expression profile that differentiates between ischemic and nonischemic cardiomyopathy. Circulation (2004) 1.47
Modulation of contractility by myocyte-derived arginase in normal and hypertrophied feline myocardium. Am J Physiol Heart Circ Physiol (2005) 1.46
Gene coexpression network topology of cardiac development, hypertrophy, and failure. Circ Cardiovasc Genet (2010) 1.46
Improved mechanical reliability of the HeartMate XVE left ventricular assist system. Ann Thorac Surg (2006) 1.45
Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations. Circ Res (2013) 1.44
The ethical attitude of emergency physicians toward resuscitation in Korea. J Emerg Med (2007) 1.44
Lipoprotein(a) as a potential causal genetic risk factor of cardiovascular disease: a rationale for increased efforts to understand its pathophysiology and develop targeted therapies. J Am Coll Cardiol (2012) 1.43
Clinical and genetic modifiers of long-term survival in heart failure. J Am Coll Cardiol (2009) 1.42