PubRank

Matthew A Perugini

Author PubWeight™ 76.44‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Size-distribution analysis of proteins by analytical ultracentrifugation: strategies and application to model systems. Biophys J 2002 5.20
2 Inhibition of lysine biosynthesis: an evolving antibiotic strategy. Mol Biosyst 2007 1.69
3 Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis. Biochem J 2008 1.46
4 Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor. Immunity 2009 1.40
5 Structure and evolution of a novel dimeric enzyme from a clinically important bacterial pathogen. J Biol Chem 2008 1.38
6 Dihydrodipicolinate synthase from Thermotoga maritima. Biochem J 2006 1.37
7 The structural basis for autonomous dimerization of the pre-T-cell antigen receptor. Nature 2010 1.35
8 The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis. Proc Natl Acad Sci U S A 2003 1.24
9 The 2.1A crystal structure of the far-red fluorescent protein HcRed: inherent conformational flexibility of the chromophore. J Mol Biol 2005 1.23
10 Age-related differences in plasma proteins: how plasma proteins change from neonates to adults. PLoS One 2011 1.22
11 Evolution of quaternary structure in a homotetrameric enzyme. J Mol Biol 2008 1.12
12 A family of helminth molecules that modulate innate cell responses via molecular mimicry of host antimicrobial peptides. PLoS Pathog 2011 1.10
13 Ribosome-inactivating proteins: current status and biomedical applications. Drug Discov Today 2012 1.08
14 Properties of GDP-mannose pyrophosphorylase, a critical enzyme and drug target in Leishmania mexicana. J Biol Chem 2004 1.05
15 Solution conformation, backbone dynamics and lipid interactions of the intrinsically unstructured malaria surface protein MSP2. J Mol Biol 2008 1.03
16 Novel Bcl-2 homology-3 domain-like sequences identified from screening randomized peptide libraries for inhibitors of the pro-survival Bcl-2 proteins. J Biol Chem 2009 1.03
17 Substrate-mediated stabilization of a tetrameric drug target reveals Achilles heel in anthrax. J Biol Chem 2009 1.03
18 The purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Clostridium botulinum. Acta Crystallogr Sect F Struct Biol Cryst Commun 2008 1.01
19 Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens? Bioorg Med Chem Lett 2007 1.01
20 The trans-Golgi network GRIP-domain proteins form alpha-helical homodimers. Biochem J 2005 1.00
21 Purification, crystallization and preliminary X-ray diffraction studies to near-atomic resolution of dihydrodipicolinate synthase from methicillin-resistant Staphylococcus aureus. Acta Crystallogr Sect F Struct Biol Cryst Commun 2008 0.99
22 Conserved main-chain peptide distortions: a proposed role for Ile203 in catalysis by dihydrodipicolinate synthase. Protein Sci 2008 0.97
23 A partially structured region of a largely unstructured protein, Plasmodium falciparum merozoite surface protein 2 (MSP2), forms amyloid-like fibrils. J Pept Sci 2007 0.96
24 Dimerization of plant defensin NaD1 enhances its antifungal activity. J Biol Chem 2012 0.96
25 Minimal requirements for actin filament disassembly revealed by structural analysis of malaria parasite actin-depolymerizing factor 1. Proc Natl Acad Sci U S A 2011 0.94
26 Crystallization and preliminary X-ray analysis of dihydrodipicolinate synthase from Clostridium botulinum in the presence of its substrate pyruvate. Acta Crystallogr Sect F Struct Biol Cryst Commun 2009 0.94
27 Crystal structure of a UDP-glucose-specific glycosyltransferase from a Mycobacterium species. J Biol Chem 2008 0.93
28 Methods for sample labeling and meniscus determination in the fluorescence-detected analytical ultracentrifuge. Anal Biochem 2009 0.92
29 Phospholipid interaction induces molecular-level polymorphism in apolipoprotein C-II amyloid fibrils via alternative assembly pathways. J Mol Biol 2007 0.92
30 Expression, purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Bacillus anthracis in the presence of pyruvate. Acta Crystallogr Sect F Struct Biol Cryst Commun 2009 0.92
31 Crystal, solution and in silico structural studies of dihydrodipicolinate synthase from the common grapevine. PLoS One 2012 0.91
32 Exploring the dihydrodipicolinate synthase tetramer: how resilient is the dimer-dimer interface? Arch Biochem Biophys 2009 0.90
33 The antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping. Proc Natl Acad Sci U S A 2013 0.89
34 Ultramarine, a chromoprotein acceptor for Förster resonance energy transfer. PLoS One 2012 0.89
35 A helical conotoxin from Conus imperialis has a novel cysteine framework and defines a new superfamily. J Biol Chem 2012 0.89
36 Irreversible inhibition of dihydrodipicolinate synthase by 4-oxo-heptenedioic acid analogues. Bioorg Med Chem 2008 0.88
37 Dimerization of bacterial diaminopimelate epimerase is essential for catalysis. J Biol Chem 2013 0.88
38 A mitochondrial protein affects cell morphology, mitochondrial segregation and virulence in Leishmania. Int J Parasitol 2006 0.88
39 X-ray crystal structure and specificity of the Plasmodium falciparum malaria aminopeptidase PfM18AAP. J Mol Biol 2012 0.87
40 Crystal structure of a BCL-W domain-swapped dimer: implications for the function of BCL-2 family proteins. Structure 2011 0.86
41 Structure of Leishmania mexicana phosphomannomutase highlights similarities with human isoforms. J Mol Biol 2006 0.86
42 A tetrameric structure is not essential for activity in dihydrodipicolinate synthase (DHDPS) from Mycobacterium tuberculosis. Arch Biochem Biophys 2011 0.86
43 Targeting of a natural killer cell receptor family by a viral immunoevasin. Nat Immunol 2013 0.86
44 Specificity versus catalytic potency: The role of threonine 44 in Escherichia coli dihydrodipicolinate synthase mediated catalysis. Biochimie 2009 0.86
45 Defining the interaction of perforin with calcium and the phospholipid membrane. Biochem J 2013 0.85
46 Catalytic mechanism and cofactor preference of dihydrodipicolinate reductase from methicillin-resistant Staphylococcus aureus. Arch Biochem Biophys 2011 0.85
47 A biophysical analysis of the tetratricopeptide repeat-rich mitochondrial import receptor, Tom70, reveals an elongated monomer that is inherently flexible, unstable, and unfolds via a multistate pathway. J Biol Chem 2004 0.85
48 Mutating the tight-dimer interface of dihydrodipicolinate synthase disrupts the enzyme quaternary structure: toward a monomeric enzyme. Biochemistry 2008 0.84
49 Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana. PLoS One 2012 0.84
50 Sources of artefacts in the electrospray ionization mass spectra of saturated diacylglycerophosphocholines: from condensed phase hydrolysis reactions through to gas phase intercluster reactions. J Am Soc Mass Spectrom 2006 0.84
51 Characterization of a novel JNK (c-Jun N-terminal kinase) inhibitory peptide. Biochem J 2011 0.84
52 Crystallization and preliminary X-ray diffraction analysis of diaminopimelate epimerase from Escherichia coli. Acta Crystallogr Sect F Struct Biol Cryst Commun 2009 0.83
53 Cloning, expression and crystallization of dihydrodipicolinate reductase from methicillin-resistant Staphylococcus aureus. Acta Crystallogr Sect F Struct Biol Cryst Commun 2009 0.82
54 Characterization of monomeric dihydrodipicolinate synthase variant reveals the importance of substrate binding in optimizing oligomerization. Biochim Biophys Acta 2011 0.81
55 Disruption of quaternary structure in Escherichia coli dihydrodipicolinate synthase (DHDPS) generates a functional monomer that is no longer inhibited by lysine. Arch Biochem Biophys 2010 0.81
56 Structural basis for the recognition and cross-linking of amyloid fibrils by human apolipoprotein E. J Biol Chem 2007 0.81
57 Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition. Plant Mol Biol 2013 0.81
58 Disarming bacterial virulence through chemical inhibition of the DNA binding domain of an AraC-like transcriptional activator protein. J Biol Chem 2013 0.81
59 A new robust kinetic assay for DAP epimerase activity. Biochimie 2013 0.80
60 Electron capture dissociation of complexes of diacylglycerophosphocholine and divalent metal ions: competition between charge reduction and radical induced phospholipid fragmentation. J Am Soc Mass Spectrom 2008 0.80
61 Aromatic residues in the C-terminal helix of human apoC-I mediate phospholipid interactions and particle morphology. J Lipid Res 2008 0.80
62 Dual roles of F123 in protein homodimerization and inhibitor binding to biotin protein ligase from Staphylococcus aureus. Mol Microbiol 2013 0.80
63 Crystallization of dihydrodipicolinate synthase from a clinical isolate of Streptococcus pneumoniae. Acta Crystallogr Sect F Struct Biol Cryst Commun 2009 0.80
64 Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the psychrophile Shewanella benthica. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 0.80
65 Caspase inhibitors of the P35 family are more active when purified from yeast than bacteria. PLoS One 2012 0.80
66 High density lipoproteins bind Abeta and apolipoprotein C-II amyloid fibrils. J Lipid Res 2006 0.80
67 Self-assembly of peptides into spherical nanoparticles for delivery of hydrophilic moieties to the cytosol. ACS Nano 2010 0.80
68 Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the grapevine Vitis vinifera. Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 0.79
69 Non-fibrillar components of amyloid deposits mediate the self-association and tangling of amyloid fibrils. J Biol Chem 2004 0.79
70 Development of the procedures for high-yield expression and rapid purification of active recombinant Csk-homologous kinase (CHK): comparison of the catalytic activities of CHK and CSK. Protein Expr Purif 2010 0.79
71 Comparative structure and function analyses of native and his-tagged forms of dihydrodipicolinate reductase from methicillin-resistant Staphylococcus aureus. Protein Expr Purif 2012 0.78
72 New method for purifying histidine-rich glycoprotein from human plasma redefines its functional properties. IUBMB Life 2013 0.77
73 A synthetic peptide that inhibits lipoprotein(a) assembly. Arterioscler Thromb Vasc Biol 2003 0.77
74 Identification of the bona fide DHDPS from a common plant pathogen. Proteins 2014 0.77
75 Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from Agrobacterium tumefaciens. Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 0.76
76 Structural features of apolipoprotein B synthetic peptides that inhibit lipoprotein(a) assembly. J Lipid Res 2004 0.75
77 Crystal structure of the Leishmania major MIX protein: a scaffold protein that mediates protein-protein interactions. Protein Sci 2011 0.75
78 Cloning to crystallization of dihydrodipicolinate synthase from the intracellular pathogen Legionella pneumophila. Acta Crystallogr Sect F Struct Biol Cryst Commun 2013 0.75
79 Fluorescence and analytical ultracentrifugation analyses of the interaction of the tyrosine kinase inhibitor, tyrphostin AG 1478-mesylate, with albumin. Anal Biochem 2005 0.75
80 Size matters! Fragmentation chemistry of [Cu(L)n]2+ complexes of diacylglycerophosphocholines as a function of coordination number (n = 2-7). Rapid Commun Mass Spectrom 2007 0.75
81 Letter: collision-induced dissociation of [metal(L)(2)](2+) complexes (metal = Cu, Ca and Mg) of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine allows distinction of the acyl groups at the sn1 and sn2 positions. Eur J Mass Spectrom (Chichester, Eng) 2007 0.75