Retracted: This article has been retracted.

Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease.

PubWeight™: 2.43‹?› | Rank: Top 2%

🔗 View Article (PMID 20062065)

Published in Nat Med on January 10, 2010

Authors

Xuebin Liu1, Stewart Leung, Chunxia Wang, Zhu Tan, Ji Wang, Taylor B Guo, Lei Fang, Yonggang Zhao, Bing Wan, Xia Qin, Limin Lu, Runsheng Li, Heng Pan, Mingjuan Song, Ailian Liu, Jian Hong, Hongtao Lu, Jingwu Z Zhang

Author Affiliations

1: Department of Neuroimmunology, GlaxoSmithKline Research and Development Center, Shanghai, China.

Articles citing this

Induction and molecular signature of pathogenic TH17 cells. Nat Immunol (2012) 4.43

Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner. Immunity (2011) 3.38

T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt. Nat Immunol (2010) 2.68

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia. Nat Genet (2011) 2.32

The many faces of Th17 cells. Curr Opin Immunol (2011) 1.84

IL-7 promotes T(H)1 development and serum IL-7 predicts clinical response to interferon-β in multiple sclerosis. Sci Transl Med (2011) 1.73

Effector and regulatory T-cell subsets in autoimmunity and tissue inflammation. Scand J Immunol (2010) 1.70

Effect of interleukin-6 receptor blockade on the balance between regulatory T cells and T helper type 17 cells in rheumatoid arthritis patients. Clin Exp Immunol (2013) 1.55

IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells. Proc Natl Acad Sci U S A (2012) 1.54

Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation. Nat Immunol (2012) 1.28

The cytokine milieu in the interplay of pathogenic Th1/Th17 cells and regulatory T cells in autoimmune disease. Cell Mol Immunol (2010) 1.21

Interleukin 7 (IL-7) selectively promotes mouse and human IL-17-producing γδ cells. Proc Natl Acad Sci U S A (2012) 1.18

IL-7 induces expression and activation of integrin α4β7 promoting naive T-cell homing to the intestinal mucosa. Blood (2012) 1.14

Immune checkpoints in central nervous system autoimmunity. Immunol Rev (2012) 1.11

T cell factor-1 negatively regulates expression of IL-17 family of cytokines and protects mice from experimental autoimmune encephalomyelitis. J Immunol (2011) 1.08

Soluble IL7Rα potentiates IL-7 bioactivity and promotes autoimmunity. Proc Natl Acad Sci U S A (2013) 1.07

Eriocalyxin B ameliorates experimental autoimmune encephalomyelitis by suppressing Th1 and Th17 cells. Proc Natl Acad Sci U S A (2013) 0.96

Rheumatoid arthritis synovial fibroblasts produce a soluble form of the interleukin-7 receptor in response to pro-inflammatory cytokines. J Cell Mol Med (2011) 0.96

Early IL-17 production by intrahepatic T cells is important for adaptive immune responses in viral hepatitis. J Immunol (2012) 0.95

The novel role of IL-7 ligation to IL-7 receptor in myeloid cells of rheumatoid arthritis and collagen-induced arthritis. J Immunol (2013) 0.95

IL-7: the global builder of the innate lymphoid network and beyond, one niche at a time. Semin Immunol (2012) 0.94

Interleukin-7 influences FOXP3+CD4+ regulatory T cells peripheral homeostasis. PLoS One (2012) 0.92

Cytokine gene polymorphisms and human autoimmune disease in the era of genome-wide association studies. J Interferon Cytokine Res (2011) 0.90

IL-17-producing NKT cells depend exclusively on IL-7 for homeostasis and survival. Mucosal Immunol (2014) 0.87

A "crossomics" study analysing variability of different components in peripheral blood of healthy caucasoid individuals. PLoS One (2012) 0.86

Janus-like effects of type I interferon in autoimmune diseases. Immunol Rev (2012) 0.86

Interleukin-12 (IL-12), but not IL-23, induces the expression of IL-7 in microglia and macrophages: implications for multiple sclerosis. Immunology (2014) 0.85

IL7Rα contributes to experimental autoimmune encephalomyelitis through altered T cell responses and nonhematopoietic cell lineages. J Immunol (2013) 0.84

Podoplanin negatively regulates CD4+ effector T cell responses. J Clin Invest (2014) 0.82

Opposing functions of IL-2 and IL-7 in the regulation of immune responses. Cytokine (2011) 0.82

IL-7 receptor blockade following T cell depletion promotes long-term allograft survival. J Clin Invest (2014) 0.81

Preferential recruitment of Th17 cells to cervical cancer via CCR6-CCL20 pathway. PLoS One (2015) 0.80

Perspectives of the relationship between IL-7 and autoimmune diseases. Clin Rheumatol (2013) 0.80

Exogenous amino acids are essential for interleukin-7 induced CD8 T cell growth. [corrected]. PLoS One (2012) 0.80

Differential response of regulatory and conventional CD4⁺ lymphocytes to CD3 engagement: clues to a possible mechanism of anti-CD3 action? J Immunol (2013) 0.80

Interleukin-7 produced by intestinal epithelial cells in response to Citrobacter rodentium infection plays a major role in innate immunity against this pathogen. Infect Immun (2015) 0.80

Interleukin-7 and Toll-like receptor 7 induce synergistic B cell and T cell activation. PLoS One (2014) 0.79

IL7R gene expression network associates with human healthy ageing. Immun Ageing (2015) 0.79

The role of interleukin-6 signalling and its therapeutic blockage in skewing the T cell balance in rheumatoid arthritis. Clin Exp Immunol (2017) 0.79

Interleukin-7 receptor single nucleotide polymorphism rs6897932 (C/T) and the susceptibility to systemic lupus erythematosus. Inflammation (2014) 0.77

Variants of Interleukin-7/Interleukin-7 Receptor Alpha are Associated with Both Neuromyelitis Optica and Multiple Sclerosis Among Chinese Han Population in Southeastern China. Chin Med J (Engl) (2015) 0.77

Empowering T helper 17 cells in autoimmunity. Nat Med (2010) 0.77

IL-7/IL-7 Receptor Signaling Differentially Affects Effector CD4+ T Cell Subsets Involved in Experimental Autoimmune Encephalomyelitis. J Immunol (2015) 0.75

Retraction: Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease. Nat Med (2013) 0.75

Ginger extract modulates the expression of IL-12 and TGF-β in the central nervous system and serum of mice with experimental autoimmune encephalomyelitis. Avicenna J Phytomed (2017) 0.75

T-bet promotes the accumulation of encephalitogenic Th17 cells in the CNS. J Neuroimmunol (2016) 0.75

Levels of hepatic Th17 cells and regulatory T cells upregulated by hepatic stellate cells in advanced HBV-related liver fibrosis. J Transl Med (2017) 0.75

Genetic association of rs1520333 G/A polymorphism in the IL7 gene with multiple sclerosis susceptibility in Isfahan population. Adv Biomed Res (2014) 0.75

Evaluation of Selected MicroRNAs Expression in Remission Phase of Multiple Sclerosis and Their Potential Link to Cognition, Depression, and Disability. J Mol Neurosci (2017) 0.75

Articles cited by this

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature (2006) 46.36

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity (2006) 29.29

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med (2005) 28.73

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol (2005) 27.17

IL-17 and Th17 Cells. Annu Rev Immunol (2009) 23.02

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature (2003) 22.89

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol (2004) 17.40

Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med (2007) 17.06

IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature (2007) 16.59

IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu Rev Immunol (2007) 14.99

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med (2006) 14.33

Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation. Immunity (2007) 12.12

IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis. J Immunol (2006) 10.33

Immunology of multiple sclerosis. Annu Rev Immunol (2005) 9.08

Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J Exp Med (2004) 8.98

A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage. Nat Med (2007) 8.97

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J Exp Med (1994) 8.97

Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med (2006) 8.41

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nat Med (2002) 8.33

Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. Immunity (2009) 8.20

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J Exp Med (1995) 7.52

IL-21 and TGF-beta are required for differentiation of human T(H)17 cells. Nature (2008) 7.00

IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc Natl Acad Sci U S A (2001) 6.91

Interleukin-17 and type 17 helper T cells. N Engl J Med (2009) 6.83

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo. Nat Immunol (2009) 6.74

New insights into the regulation of T cells by gamma(c) family cytokines. Nat Rev Immunol (2009) 5.57

Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell (2002) 5.44

TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1. Nat Med (2007) 5.41

Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis. Am J Pathol (2007) 5.27

Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. Nat Genet (2007) 5.09

Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis. Mult Scler (1999) 4.91

Multiple sclerosis: a complicated picture of autoimmunity. Nat Immunol (2007) 4.87

Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis. J Clin Invest (2006) 4.77

Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis. Nat Genet (2007) 4.22

Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells. Nat Immunol (2003) 3.82

The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance. J Immunol (2005) 3.51

Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells. J Exp Med (2008) 3.50

Natural recovery and protection from autoimmune encephalomyelitis: contribution of CD4+CD25+ regulatory cells within the central nervous system. J Immunol (2005) 3.41

IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A (2008) 2.60

Cell biology of IL-7, a key lymphotrophin. Cytokine Growth Factor Rev (2005) 2.35

STAT3 and NF-kappaB signal pathway is required for IL-23-mediated IL-17 production in spontaneous arthritis animal model IL-1 receptor antagonist-deficient mice. J Immunol (2006) 2.31

Loss of STAT3 in CD4+ T cells prevents development of experimental autoimmune diseases. J Immunol (2008) 2.22

IL-23 promotes maintenance but not commitment to the Th17 lineage. J Immunol (2008) 2.06

Role of IFN-gamma in induction of Foxp3 and conversion of CD4+ CD25- T cells to CD4+ Tregs. J Clin Invest (2006) 2.02

A shift from adaptive to innate immunity: a potential mechanism of disease progression in multiple sclerosis. J Neurol (2008) 1.74

Uncoupling of proliferation and Stat5 activation in thymic stromal lymphopoietin-mediated signal transduction. J Immunol (2002) 1.65

STAT3 in CD4+ T helper cell differentiation and inflammatory diseases. Cytokine (2009) 1.55

TSLP and IL-7 use two different mechanisms to regulate human CD4+ T cell homeostasis. J Exp Med (2009) 1.39

CD4+CD25+FoxP3+ T lymphocytes fail to suppress myelin basic protein-induced proliferation in patients with multiple sclerosis. J Neuroimmunol (2006) 1.36

Interleukin-7 receptor signaling network: an integrated systems perspective. Cell Mol Immunol (2008) 1.22

Interferon gamma, interleukin 4 and transforming growth factor beta in experimental autoimmune encephalomyelitis in Lewis rats: dynamics of cellular mRNA expression in the central nervous system and lymphoid cells. J Neurosci Res (1995) 1.13

IL-7/STAT5 cytokine signaling pathway is essential but insufficient for maintenance of naive CD4 T cell survival in peripheral lymphoid organs. J Immunol (2007) 1.11

Preferential expansion of autoreactive T lymphocytes from the memory T-cell pool by IL-7. J Neuroimmunol (1999) 1.02

Building different mouse models for human MS. Ann N Y Acad Sci (2007) 1.00

Depletion of CD4(+)CD25(+) T cells exacerbates experimental autoimmune encephalomyelitis induced by mouse, but not rat, antigens. J Neurosci Res (2009) 0.90

IL-15 and psoriasis: another genetic link to Th17? J Invest Dermatol (2007) 0.88

Articles by these authors

PATRIC: the comprehensive bacterial bioinformatics resource with a focus on human pathogenic species. Infect Immun (2011) 4.57

Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis. Nat Med (2013) 2.85

A strong ferroelectric ferromagnet created by means of spin-lattice coupling. Nature (2010) 2.63

EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin. Mol Cell (2009) 2.50

Depression in older people in rural China. Arch Intern Med (2005) 2.28

miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. J Cell Biol (2012) 2.15

Critical regulation of CD4+ T cell survival and autoimmunity by beta-arrestin 1. Nat Immunol (2007) 2.15

Aberrant regulation of synovial T cell activation by soluble costimulatory molecules in rheumatoid arthritis. J Immunol (2006) 2.15

Role of IFN-gamma in induction of Foxp3 and conversion of CD4+ CD25- T cells to CD4+ Tregs. J Clin Invest (2006) 2.02

Renal medullary microRNAs in Dahl salt-sensitive rats: miR-29b regulates several collagens and related genes. Hypertension (2010) 1.94

Upregulation of Cyclin B1 by miRNA and its implications in cancer. Nucleic Acids Res (2011) 1.84

Severity of depression and risk for subsequent dementia: cohort studies in China and the UK. Br J Psychiatry (2008) 1.81

Regulatory effects of IFN-beta on production of osteopontin and IL-17 by CD4+ T Cells in MS. Eur J Immunol (2009) 1.81

RNAa is conserved in mammalian cells. PLoS One (2010) 1.81

Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Genes Dev (2012) 1.64

Overview of the ID, EPI and REL tasks of BioNLP Shared Task 2011. BMC Bioinformatics (2012) 1.62

Role of osteopontin in synovial Th17 differentiation in rheumatoid arthritis. Arthritis Rheum (2010) 1.62

LncRNAs expression signatures of renal clear cell carcinoma revealed by microarray. PLoS One (2012) 1.59

Induction of CD4+CD25+ regulatory T cells by copolymer-I through activation of transcription factor Foxp3. Proc Natl Acad Sci U S A (2005) 1.57

Leucine deprivation increases hepatic insulin sensitivity via GCN2/mTOR/S6K1 and AMPK pathways. Diabetes (2011) 1.55

Liver X receptor (LXR) mediates negative regulation of mouse and human Th17 differentiation. J Clin Invest (2011) 1.54

Vaccination with selected synovial T cells in rheumatoid arthritis. Arthritis Rheum (2007) 1.53

Combination small molecule MEK and PI3K inhibition enhances uveal melanoma cell death in a mutant GNAQ- and GNA11-dependent manner. Clin Cancer Res (2012) 1.52

Composition, sources, and potential toxicological significance of PAHs in the surface sediments of the Meiliang Bay, Taihu Lake, China. Environ Int (2005) 1.51

Formation of complexes at plasmodesmata for potyvirus intercellular movement is mediated by the viral protein P3N-PIPO. PLoS Pathog (2010) 1.50

Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine. Mol Pharmacol (2010) 1.48

Use of remote centralized raters via live 2-way video in a multicenter clinical trial for schizophrenia. J Clin Psychopharmacol (2008) 1.46

Kinetic differences in the induction of interferon stimulated genes by interferon-α and interleukin 28B are altered by infection with hepatitis C virus. Hepatology (2014) 1.46

Role of osteopontin in amplification and perpetuation of rheumatoid synovitis. J Clin Invest (2005) 1.42

c-Jun downregulation by HDAC3-dependent transcriptional repression promotes osmotic stress-induced cell apoptosis. Mol Cell (2007) 1.40

Abnormal expression of Toll-like receptor 4 is associated with susceptibility to ethanol-induced gastric mucosal injury in mice. Dig Dis Sci (2013) 1.39

Characterization of a high-activity mutant of human butyrylcholinesterase against (-)-cocaine. Chem Biol Interact (2010) 1.39

Identification of MACC1 as a novel prognostic marker in hepatocellular carcinoma. J Transl Med (2011) 1.38

Leukemia inhibitory factor inhibits T helper 17 cell differentiation and confers treatment effects of neural progenitor cell therapy in autoimmune disease. Immunity (2011) 1.38

Critical and reciprocal regulation of KLF4 and SLUG in transforming growth factor β-initiated prostate cancer epithelial-mesenchymal transition. Mol Cell Biol (2011) 1.34

Berberine differentially modulates the activities of ERK, p38 MAPK, and JNK to suppress Th17 and Th1 T cell differentiation in type 1 diabetic mice. J Biol Chem (2009) 1.33

Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis. J Neuroimmunol (2009) 1.32

Recombination of CXCR4, VEGF, and MMP-9 predicting lymph node metastasis in human breast cancer. Cancer Lett (2007) 1.27

Length of stay data as a guide to hospital economic performance for ICU patients. Med Care (2003) 1.27

Angiogenesis by transplantation of HIF-1 alpha modified EPCs into ischemic limbs. J Cell Biochem (2008) 1.25

Rescue of mesangial cells from high glucose-induced over-proliferation and extracellular matrix secretion by hydrogen sulfide. Nephrol Dial Transplant (2011) 1.24

SIRT1 activators suppress inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB activity. PLoS One (2012) 1.23

A catenated strut in a catenated metal-organic framework. Angew Chem Int Ed Engl (2010) 1.22

The cytokine milieu in the interplay of pathogenic Th1/Th17 cells and regulatory T cells in autoimmune disease. Cell Mol Immunol (2010) 1.21

Leucine deprivation decreases fat mass by stimulation of lipolysis in white adipose tissue and upregulation of uncoupling protein 1 (UCP1) in brown adipose tissue. Diabetes (2009) 1.20

Sequential recruitment of the endoplasmic reticulum and chloroplasts for plant potyvirus replication. J Virol (2009) 1.20

Carbon monoxide enhances salt tolerance by nitric oxide-mediated maintenance of ion homeostasis and up-regulation of antioxidant defence in wheat seedling roots. Plant Cell Environ (2008) 1.20

"Turn-on" fluorescent sensor for Hg2+ via displacement approach. Inorg Chem (2008) 1.19

Synovial autoreactive T cells in rheumatoid arthritis resist IDO-mediated inhibition. J Immunol (2006) 1.19

Association of CD4+CD25+Foxp3+ regulatory T cells with chronic activity and viral clearance in patients with hepatitis B. Int Immunol (2006) 1.18

Ago1 Interacts with RNA polymerase II and binds to the promoters of actively transcribed genes in human cancer cells. PLoS Genet (2013) 1.18

Primary hyperparathyroidism is associated with abnormal cortical and trabecular microstructure and reduced bone stiffness in postmenopausal women. J Bone Miner Res (2013) 1.17

A mechanical actuator driven electrochemically by artificial molecular muscles. ACS Nano (2009) 1.16

Integrated materials design of organic semiconductors for field-effect transistors. J Am Chem Soc (2013) 1.16

Total synthesis of polycavernoside A, a lethal toxin of the red alga Polycavernosa tsudai. J Org Chem (2005) 1.14

A rapid and simple isothermal nucleic acid amplification test for detection of herpes simplex virus types 1 and 2. J Clin Virol (2010) 1.13

Cross-reactivity with myelin basic protein and human herpesvirus-6 in multiple sclerosis. Ann Neurol (2003) 1.13

Electric field manipulation of magnetization rotation and tunneling magnetoresistance of magnetic tunnel junctions at room temperature. Adv Mater (2014) 1.13

Residues and source identification of persistent organic pollutants in farmland soils irrigated by effluents from biological treatment plants. Environ Int (2005) 1.12

MEKK1 mediates the ubiquitination and degradation of c-Jun in response to osmotic stress. Mol Cell Biol (2006) 1.12

Anti beta2-microglobulin monoclonal antibodies induce apoptosis in myeloma cells by recruiting MHC class I to and excluding growth and survival cytokine receptors from lipid rafts. Blood (2007) 1.12

Role of osteopontin in induction of monocyte chemoattractant protein 1 and macrophage inflammatory protein 1beta through the NF-kappaB and MAPK pathways in rheumatoid arthritis. Arthritis Rheum (2009) 1.11

Rabbit embryonic stem cell lines derived from fertilized, parthenogenetic or somatic cell nuclear transfer embryos. Exp Cell Res (2006) 1.10

Trabecular bone score (TBS)--a novel method to evaluate bone microarchitectural texture in patients with primary hyperparathyroidism. J Clin Endocrinol Metab (2013) 1.10

Cyclophilin A is required for CXCR4-mediated nuclear export of heterogeneous nuclear ribonucleoprotein A2, activation and nuclear translocation of ERK1/2, and chemotactic cell migration. J Biol Chem (2007) 1.09

Increased CD8+ cytotoxic T cell responses to myelin basic protein in multiple sclerosis. J Immunol (2004) 1.09

Embryonic stem cells generated by nuclear transfer of human somatic nuclei into rabbit oocytes. Cell Res (2003) 1.08

Musashi2 predicts poor prognosis and invasion in hepatocellular carcinoma by driving epithelial-mesenchymal transition. J Cell Mol Med (2013) 1.06

Role of Sox2 and Oct4 in predicting survival of hepatocellular carcinoma patients after hepatectomy. Clin Biochem (2011) 1.06

Electric pulses applied prior to intramuscular DNA vaccination greatly improve the vaccine immunogenicity. Vaccine (2006) 1.05

Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy. Autophagy (2012) 1.05

Antitumor activity of a novel oncrasin analogue is mediated by JNK activation and STAT3 inhibition. PLoS One (2011) 1.04

Direct nanoimprinting of metal nanoparticles for nanoscale electronics fabrication. Nano Lett (2007) 1.04

CXCL12 induces tyrosine phosphorylation of cortactin, which plays a role in CXC chemokine receptor 4-mediated extracellular signal-regulated kinase activation and chemotaxis. J Biol Chem (2006) 1.04

IL-21 regulates Th17 cells in rheumatoid arthritis. Hum Immunol (2010) 1.03