Published in PLoS One on January 06, 2010
Ambiguities in helical reconstruction. Elife (2014) 1.19
The recombinases DMC1 and RAD51 are functionally and spatially separated during meiosis in Arabidopsis. Plant Cell (2012) 1.09
DNA strand exchange and RecA homologs in meiosis. Cold Spring Harb Perspect Biol (2014) 0.97
The resistance of DMC1 D-loops to dissociation may account for the DMC1 requirement in meiosis. Nat Struct Mol Biol (2010) 0.97
Helical filaments of human Dmc1 protein on single-stranded DNA: a cautionary tale. J Mol Biol (2010) 0.96
An interaction between DNA polymerase and helicase is essential for the high processivity of the bacteriophage T7 replisome. J Biol Chem (2012) 0.90
Connecting by breaking and repairing: mechanisms of DNA strand exchange in meiotic recombination. FEBS J (2015) 0.84
Details of ssDNA annealing revealed by an HSV-1 ICP8-ssDNA binary complex. Nucleic Acids Res (2013) 0.83
Functional attributes of the Saccharomyces cerevisiae meiotic recombinase Dmc1. DNA Repair (Amst) (2013) 0.81
Role of the conserved lysine within the Walker A motif of human DMC1. DNA Repair (Amst) (2012) 0.80
Nanobiomotors of archaeal DNA repair machineries: current research status and application potential. Cell Biosci (2014) 0.80
Crystal structure of Hop2-Mnd1 and mechanistic insights into its role in meiotic recombination. Nucleic Acids Res (2015) 0.78
Conserved Streptococcus pneumoniae spirosomes suggest a single type of transformation pilus in competence. PLoS Pathog (2015) 0.76
High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy. Nucleic Acids Res (2016) 0.76
Structural and Functional Studies of H. seropedicae RecA Protein - Insights into the Polymerization of RecA Protein as Nucleoprotein Filament. PLoS One (2016) 0.75
UCSF Chimera--a visualization system for exploratory research and analysis. J Comput Chem (2004) 112.47
SWISS-MODEL: An automated protein homology-modeling server. Nucleic Acids Res (2003) 25.86
SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields. J Struct Biol (1996) 22.89
Genome maintenance mechanisms for preventing cancer. Nature (2001) 16.17
A new generation of the IMAGIC image processing system. J Struct Biol (1996) 12.57
DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression. Cell (1992) 10.48
Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family. Cell (1997) 10.32
Molecular views of recombination proteins and their control. Nat Rev Mol Cell Biol (2003) 6.96
The single-end invasion: an asymmetric intermediate at the double-strand break to double-holliday junction transition of meiotic recombination. Cell (2001) 5.94
Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures. Nature (2008) 5.85
The structure of the E. coli recA protein monomer and polymer. Nature (1992) 5.77
DNA double-strand break repair: all's well that ends well. Annu Rev Genet (2006) 5.59
Single-particle electron cryo-microscopy: towards atomic resolution. Q Rev Biophys (2000) 4.86
Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA. EMBO J (1994) 4.55
3D domain swapping: as domains continue to swap. Protein Sci (2002) 4.35
Interhomolog bias during meiotic recombination: meiotic functions promote a highly differentiated interhomolog-only pathway. Cell (1997) 4.30
Chromosome choreography: the meiotic ballet. Science (2003) 4.00
Meiotic prophase arrest with failure of chromosome synapsis in mice deficient for Dmc1, a germline-specific RecA homolog. Mol Cell (1998) 3.81
Three-dimensional reconstruction of single particles from random and nonrandom tilt series. J Electron Microsc Tech (1988) 3.63
The mouse RecA-like gene Dmc1 is required for homologous chromosome synapsis during meiosis. Mol Cell (1998) 3.22
Clarifying the mechanics of DNA strand exchange in meiotic recombination. Nature (2006) 3.02
Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2. EMBO J (2003) 2.95
Crystal structure of a Rad51 filament. Nat Struct Mol Biol (2004) 2.83
The portal protein of bacteriophage SPP1: a DNA pump with 13-fold symmetry. EMBO J (1993) 2.55
On the fitting of model electron densities into EM reconstructions: a reciprocal-space formulation. Acta Crystallogr D Biol Crystallogr (2002) 2.53
Elongation of duplex DNA by recA protein. J Mol Biol (1981) 2.15
Domain structure and dynamics in the helical filaments formed by RecA and Rad51 on DNA. Proc Natl Acad Sci U S A (2001) 2.03
The Rad51/RadA N-terminal domain activates nucleoprotein filament ATPase activity. Structure (2006) 2.00
ATP-mediated conformational changes in the RecA filament. Structure (2003) 1.79
Variation in human meiotic recombination. Annu Rev Genomics Hum Genet (2004) 1.70
Human meiotic recombinase Dmc1 promotes ATP-dependent homologous DNA strand exchange. Nature (2004) 1.70
Crystal structure of archaeal recombinase RADA: a snapshot of its extended conformation. Mol Cell (2004) 1.65
The Rad51 and Dmc1 recombinases: a non-identical twin relationship. Trends Biochem Sci (2001) 1.64
The N-terminal domain of the human Rad51 protein binds DNA: structure and a DNA binding surface as revealed by NMR. J Mol Biol (1999) 1.64
Structural basis for octameric ring formation and DNA interaction of the human homologous-pairing protein Dmc1. Mol Cell (2004) 1.57
Human Dmc1 protein binds DNA as an octameric ring. Proc Natl Acad Sci U S A (1999) 1.53
Archaeal RadA protein binds DNA as both helical filaments and octameric rings. J Mol Biol (2001) 1.51
A comparative analysis of Dmc1 and Rad51 nucleoprotein filaments. Nucleic Acids Res (2008) 1.46
Recognition and separation of single particles with size variation by statistical analysis of their images. J Mol Biol (2004) 1.45
Activation of human meiosis-specific recombinase Dmc1 by Ca2+. J Biol Chem (2005) 1.43
Principles of organization in S layers. J Mol Biol (1986) 1.40
The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51. EMBO J (1999) 1.40
An extended DNA structure through deoxyribose-base stacking induced by RecA protein. Proc Natl Acad Sci U S A (1997) 1.26
Crystal structure of an ATPase-active form of Rad51 homolog from Methanococcus voltae. Insights into potassium dependence. J Biol Chem (2004) 1.23
A dominant, recombination-defective allele of Dmc1 causing male-specific sterility. PLoS Biol (2007) 1.19
A possible role of the C-terminal domain of the RecA protein. A gateway model for double-stranded DNA binding. J Biol Chem (1996) 1.16
Crystal structures of Escherichia coli RecA in a compressed helical filament. J Mol Biol (2004) 1.14
Crystal structure of the left-handed archaeal RadA helical filament: identification of a functional motif for controlling quaternary structures and enzymatic functions of RecA family proteins. Nucleic Acids Res (2007) 1.12
Calcium ion promotes yeast Dmc1 activity via formation of long and fine helical filaments with single-stranded DNA. J Biol Chem (2005) 1.09
DNA recombination and repair in the archaea. Adv Appl Microbiol (2001) 1.08
The synaptic activity of HsDmc1, a human recombination protein specific to meiosis. Proc Natl Acad Sci U S A (2001) 1.02
Role of the N-terminal domain of the human DMC1 protein in octamer formation and DNA binding. J Biol Chem (2005) 0.96
Does a stretched DNA structure dictate the helical geometry of RecA-like filaments? J Mol Biol (2001) 0.91
Structural and functional analyses of five conserved positively charged residues in the L1 and N-terminal DNA binding motifs of archaeal RADA protein. PLoS One (2007) 0.89
Molecular visualization of the yeast Dmc1 protein ring and Dmc1-ssDNA nucleoprotein complex. Biochemistry (2005) 0.89
Multiple mechanisms of meiotic recombination. Cell (2006) 0.84
Structural basis of pore formation by the bacterial toxin pneumolysin. Cell (2005) 2.87
Novel pro- and anti-recombination activities of the Bloom's syndrome helicase. Genes Dev (2007) 2.82
Saccharomyces cerevisiae Mer3 helicase stimulates 3'-5' heteroduplex extension by Rad51; implications for crossover control in meiotic recombination. Cell (2004) 2.79
Ca2+ activates human homologous recombination protein Rad51 by modulating its ATPase activity. Proc Natl Acad Sci U S A (2004) 2.74
Structural framework for DNA translocation via the viral portal protein. EMBO J (2007) 2.58
Structure of the Escherichia coli ribosomal termination complex with release factor 2. Nature (2003) 2.54
Structure of a type IV secretion system core complex. Science (2009) 2.36
Structure of the SWI2/SNF2 chromatin-remodeling domain of eukaryotic Rad54. Nat Struct Mol Biol (2005) 2.25
The structural basis for membrane binding and pore formation by lymphocyte perforin. Nature (2010) 2.23
Rad54 protein promotes branch migration of Holliday junctions. Nature (2006) 2.08
Structure of bacteriophage SPP1 tail reveals trigger for DNA ejection. EMBO J (2007) 1.81
Atomic structure and hierarchical assembly of a cross-β amyloid fibril. Proc Natl Acad Sci U S A (2013) 1.75
Rad54 dissociates homologous recombination intermediates by branch migration. Nat Struct Mol Biol (2007) 1.61
Complex formation by the human Rad51B and Rad51C DNA repair proteins and their activities in vitro. J Biol Chem (2002) 1.60
Structure of bacteriophage SPP1 head-to-tail connection reveals mechanism for viral DNA gating. Proc Natl Acad Sci U S A (2009) 1.56
Topologies of a substrate protein bound to the chaperonin GroEL. Mol Cell (2007) 1.52
Human Rad54 protein stimulates DNA strand exchange activity of hRad51 protein in the presence of Ca2+. J Biol Chem (2004) 1.48
Recognition and separation of single particles with size variation by statistical analysis of their images. J Mol Biol (2004) 1.45
Detection and separation of heterogeneity in molecular complexes by statistical analysis of their two-dimensional projections. J Struct Biol (2007) 1.45
Activation of human meiosis-specific recombinase Dmc1 by Ca2+. J Biol Chem (2005) 1.43
FANCJ uses its motor ATPase to destabilize protein-DNA complexes, unwind triplexes, and inhibit RAD51 strand exchange. J Biol Chem (2009) 1.43
Challenges at the frontiers of structural biology. Nat Struct Biol (2002) 1.39
Identification of specific inhibitors of human RAD51 recombinase using high-throughput screening. ACS Chem Biol (2011) 1.30
The structure of p53 tumour suppressor protein reveals the basis for its functional plasticity. EMBO J (2006) 1.26
Dodecameric structure of the small heat shock protein Acr1 from Mycobacterium tuberculosis. J Biol Chem (2005) 1.24
Direct three-dimensional visualization of membrane disruption by amyloid fibrils. Proc Natl Acad Sci U S A (2012) 1.24
Globular tetramers of beta(2)-microglobulin assemble into elaborate amyloid fibrils. J Mol Biol (2009) 1.21
Human Rad52 binds and wraps single-stranded DNA and mediates annealing via two hRad52-ssDNA complexes. Nucleic Acids Res (2010) 1.19
RECQ1 possesses DNA branch migration activity. J Biol Chem (2008) 1.19
Rad54, the motor of homologous recombination. DNA Repair (Amst) (2010) 1.18
Removal of divalent cations induces structural transitions in red clover necrotic mosaic virus, revealing a potential mechanism for RNA release. J Virol (2006) 1.14
Structure of the VirB4 ATPase, alone and bound to the core complex of a type IV secretion system. Proc Natl Acad Sci U S A (2012) 1.12
Inhibition of homologous recombination in human cells by targeting RAD51 recombinase. J Med Chem (2012) 1.10
Elongated oligomers assemble into mammalian PrP amyloid fibrils. J Mol Biol (2006) 1.10
Hexameric ring structure of human MCM10 DNA replication factor. EMBO Rep (2007) 1.10
Interactions of human rad54 protein with branched DNA molecules. J Biol Chem (2007) 1.08
Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26. Structure (2006) 1.06
Structure of a bacterial type IV secretion core complex at subnanometre resolution. EMBO J (2013) 1.05
Bloom syndrome helicase stimulates RAD51 DNA strand exchange activity through a novel mechanism. J Biol Chem (2009) 1.04
Interaction of the mediator head module with RNA polymerase II. Structure (2012) 1.02
Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes. Blood (2010) 1.02
Mutant alpha-latrotoxin (LTXN4C) does not form pores and causes secretion by receptor stimulation: this action does not require neurexins. J Biol Chem (2003) 1.02
Structure and subunit arrangement of the A-type ATP synthase complex from the archaeon Methanococcus jannaschii visualized by electron microscopy. J Biol Chem (2004) 1.01
4.6A Cryo-EM reconstruction of tobacco mosaic virus from images recorded at 300 keV on a 4k x 4k CCD camera. J Struct Biol (2010) 1.00
Structure of triglyceride-rich human low-density lipoproteins according to cryoelectron microscopy. Biochemistry (2003) 0.98
Cooperation of RAD51 and RAD54 in regression of a model replication fork. Nucleic Acids Res (2010) 0.97
The resistance of DMC1 D-loops to dissociation may account for the DMC1 requirement in meiosis. Nat Struct Mol Biol (2010) 0.97
Structural biology of the p53 tumour suppressor. Curr Opin Struct Biol (2009) 0.96
A role for SSRP1 in recombination-mediated DNA damage response. J Cell Biochem (2009) 0.95
Capsid structure and its stability at the late stages of bacteriophage SPP1 assembly. J Virol (2012) 0.94
An expanded and flexible form of the vacuolar ATPase membrane sector. Structure (2006) 0.92
Human Rad54 protein stimulates human Mus81-Eme1 endonuclease. Proc Natl Acad Sci U S A (2008) 0.91
Molecular structure of human geminin. Nat Struct Mol Biol (2004) 0.91
Structural analysis of the Saf pilus by electron microscopy and image processing. J Mol Biol (2008) 0.90
Rad51 protein stimulates the branch migration activity of Rad54 protein. J Biol Chem (2008) 0.90
Genome gating in tailed bacteriophage capsids. Adv Exp Med Biol (2012) 0.89
Quaternary structure of the specific p53-DNA complex reveals the mechanism of p53 mutant dominance. Nucleic Acids Res (2011) 0.89
The dual role of HOP2 in mammalian meiotic homologous recombination. Nucleic Acids Res (2013) 0.88
Analyzing the branch migration activities of eukaryotic proteins. Methods (2010) 0.88
Lengsin is a survivor of an ancient family of class I glutamine synthetases re-engineered by evolution for a role in the vertebrate lens. Structure (2006) 0.87
Polarity and bypass of DNA heterology during branch migration of Holliday junctions by human RAD54, BLM, and RECQ1 proteins. J Biol Chem (2012) 0.86
The RecA/RAD51 protein drives migration of Holliday junctions via polymerization on DNA. Proc Natl Acad Sci U S A (2011) 0.83
Formation of nucleoprotein RecA filament on single-stranded DNA. Analysis by stepwise increase in ligand complexity. FEBS J (2005) 0.82
Reconstituting the key steps of the DNA double-strand break repair in vitro. Methods Mol Biol (2011) 0.78
Analysis of the activities of RAD54, a SWI2/SNF2 protein, using a specific small-molecule inhibitor. J Biol Chem (2013) 0.77
Determination of Escherichia coli RNA polymerase structure by single particle cryoelectron microscopy. Methods Enzymol (2003) 0.77
Quaternary structure of the European spiny lobster (Palinurus elephas) 1x6-mer hemocyanin from cryoEM and amino acid sequence data. J Mol Biol (2003) 0.77