Published in J Mol Biol on April 03, 2008
Architectures and biogenesis of non-flagellar protein appendages in Gram-negative bacteria. EMBO J (2008) 1.48
Chaperone-usher fimbriae of Escherichia coli. PLoS One (2013) 1.17
Supramolecular organization of the repetitive backbone unit of the Streptococcus pneumoniae pilus. PLoS One (2010) 1.11
Analysis of the role of 13 major fimbrial subunits in colonisation of the chicken intestines by Salmonella enterica serovar Enteritidis reveals a role for a novel locus. BMC Microbiol (2008) 0.92
Structural insight into host recognition by aggregative adherence fimbriae of enteroaggregative Escherichia coli. PLoS Pathog (2014) 0.90
SYBR®Green qPCR Salmonella detection system allowing discrimination at the genus, species and subspecies levels. Appl Microbiol Biotechnol (2013) 0.90
Structural basis for the specific recognition of dual receptors by the homopolymeric pH 6 antigen (Psa) fimbriae of Yersinia pestis. Proc Natl Acad Sci U S A (2012) 0.84
Reversible non-stick behaviour of a bacterial protein polymer provides a tuneable molecular mimic for cell and tissue engineering. Adv Mater (2014) 0.75
Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. Mol Microbiol (2002) 3.26
Structural basis of pore formation by the bacterial toxin pneumolysin. Cell (2005) 2.87
Fiber formation across the bacterial outer membrane by the chaperone/usher pathway. Cell (2008) 2.69
Structural framework for DNA translocation via the viral portal protein. EMBO J (2007) 2.58
The structural biology of type IV secretion systems. Nat Rev Microbiol (2009) 2.54
Chaperone priming of pilus subunits facilitates a topological transition that drives fiber formation. Cell (2002) 2.54
Structure of the Escherichia coli ribosomal termination complex with release factor 2. Nature (2003) 2.54
Structure of a type IV secretion system core complex. Science (2009) 2.36
Structure and mechanism of DNA polymerases. Adv Protein Chem (2005) 2.36
VirB11 ATPases are dynamic hexameric assemblies: new insights into bacterial type IV secretion. EMBO J (2003) 2.23
The structural basis for membrane binding and pore formation by lymphocyte perforin. Nature (2010) 2.23
Structure of the outer membrane complex of a type IV secretion system. Nature (2009) 2.17
Motions of the fingers subdomain of klentaq1 are fast and not rate limiting: implications for the molecular basis of fidelity in DNA polymerases. Mol Cell (2005) 2.15
TraG-like proteins of DNA transfer systems and of the Helicobacter pylori type IV secretion system: inner membrane gate for exported substrates? J Bacteriol (2002) 2.04
Fiber assembly by the chaperone-usher pathway. Biochim Biophys Acta (2004) 1.89
Protein modification, bioconjugation, and disulfide bridging using bromomaleimides. J Am Chem Soc (2010) 1.89
Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria. Proc Natl Acad Sci U S A (2006) 1.87
Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted beta strand displacement mechanism. Mol Cell (2006) 1.81
Structure of bacteriophage SPP1 tail reveals trigger for DNA ejection. EMBO J (2007) 1.81
Atomic structure and hierarchical assembly of a cross-β amyloid fibril. Proc Natl Acad Sci U S A (2013) 1.75
Type IV secretion systems: versatility and diversity in function. Cell Microbiol (2010) 1.75
Unveiling molecular scaffolds of the type IV secretion system. J Bacteriol (2004) 1.74
Protein-protein interaction through beta-strand addition. Trends Biochem Sci (2006) 1.69
Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate. Nature (2011) 1.67
Structure of the outer membrane translocator domain of the Haemophilus influenzae Hia trimeric autotransporter. EMBO J (2006) 1.64
Structure of bacteriophage SPP1 head-to-tail connection reveals mechanism for viral DNA gating. Proc Natl Acad Sci U S A (2009) 1.56
Structural basis for host recognition by the Haemophilus influenzae Hia autotransporter. EMBO J (2004) 1.53
Topologies of a substrate protein bound to the chaperonin GroEL. Mol Cell (2007) 1.52
Architectures and biogenesis of non-flagellar protein appendages in Gram-negative bacteria. EMBO J (2008) 1.48
Crystal structure of a vFlip-IKKgamma complex: insights into viral activation of the IKK signalosome. Mol Cell (2008) 1.46
Recognition and separation of single particles with size variation by statistical analysis of their images. J Mol Biol (2004) 1.45
Detection and separation of heterogeneity in molecular complexes by statistical analysis of their two-dimensional projections. J Struct Biol (2007) 1.45
Molecular recognition by SH2 domains. Adv Protein Chem (2002) 1.40
Structural and functional characterization of the VirB5 protein from the type IV secretion system encoded by the conjugative plasmid pKM101. Proc Natl Acad Sci U S A (2003) 1.39
Challenges at the frontiers of structural biology. Nat Struct Biol (2002) 1.39
Structures of two core subunits of the bacterial type IV secretion system, VirB8 from Brucella suis and ComB10 from Helicobacter pylori. Proc Natl Acad Sci U S A (2005) 1.39
Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis. Chem Commun (Camb) (2011) 1.38
Semisynthetic Src SH2 domains demonstrate altered phosphopeptide specificity induced by incorporation of unnatural lysine derivatives. Chem Biol (2010) 1.38
The 2B domain of the Escherichia coli Rep protein is not required for DNA helicase activity. Proc Natl Acad Sci U S A (2002) 1.37
The C-terminal domain of full-length E. coli SSB is disordered even when bound to DNA. Protein Sci (2004) 1.31
Structural biology of bacterial pathogenesis. Curr Opin Struct Biol (2004) 1.28
VirB2 and VirB5 proteins: specialized adhesins in bacterial type-IV secretion systems? Trends Microbiol (2008) 1.27
The structure of p53 tumour suppressor protein reveals the basis for its functional plasticity. EMBO J (2006) 1.26
A large domain swap in the VirB11 ATPase of Brucella suis leaves the hexameric assembly intact. J Mol Biol (2006) 1.26
Dodecameric structure of the small heat shock protein Acr1 from Mycobacterium tuberculosis. J Biol Chem (2005) 1.24
Direct three-dimensional visualization of membrane disruption by amyloid fibrils. Proc Natl Acad Sci U S A (2012) 1.24
Design and synthesis of C-2 substituted thiazolo and dihydrothiazolo ring-fused 2-pyridones: pilicides with increased antivirulence activity. J Med Chem (2010) 1.22
Agrobacterium VirB10 domain requirements for type IV secretion and T pilus biogenesis. Mol Microbiol (2008) 1.21
Globular tetramers of beta(2)-microglobulin assemble into elaborate amyloid fibrils. J Mol Biol (2009) 1.21
Biochemical characterization of protein complexes from the Helicobacter pylori protein interaction map: strategies for complex formation and evidence for novel interactions within type IV secretion systems. Mol Cell Proteomics (2004) 1.20
Chaperone-usher pathways: diversity and pilus assembly mechanism. Philos Trans R Soc Lond B Biol Sci (2012) 1.18
Molecular mechanism of P pilus termination in uropathogenic Escherichia coli. EMBO Rep (2006) 1.18
Architecture of the Helicobacter pylori Cag-type IV secretion system. FEBS J (2011) 1.16
Bromopyridazinedione-mediated protein and peptide bioconjugation. Chem Commun (Camb) (2011) 1.15
Unraveling the molecular basis of subunit specificity in P pilus assembly by mass spectrometry. Proc Natl Acad Sci U S A (2008) 1.14
NMR structure of a complex between the VirB9/VirB7 interaction domains of the pKM101 type IV secretion system. Proc Natl Acad Sci U S A (2007) 1.14
Removal of divalent cations induces structural transitions in red clover necrotic mosaic virus, revealing a potential mechanism for RNA release. J Virol (2006) 1.14
Calorimetric and structural studies of 1,2,3-trisubstituted cyclopropanes as conformationally constrained peptide inhibitors of Src SH2 domain binding. J Am Chem Soc (2002) 1.13
Structure of the VirB4 ATPase, alone and bound to the core complex of a type IV secretion system. Proc Natl Acad Sci U S A (2012) 1.12
A pre-equilibrium before nucleotide binding limits fingers subdomain closure by Klentaq1. J Biol Chem (2007) 1.12
Small heat-shock protein HSPB1 mutants stabilize microtubules in Charcot-Marie-Tooth neuropathy. J Neurosci (2011) 1.12
Structural and energetic basis of folded-protein transport by the FimD usher. Nature (2013) 1.11
Crystal structure of the P pilus rod subunit PapA. PLoS Pathog (2007) 1.11
Two-step and one-step secretion mechanisms in Gram-negative bacteria: contrasting the type IV secretion system and the chaperone-usher pathway of pilus biogenesis. Biochem J (2010) 1.11
The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket. J Biol Chem (2004) 1.10
Elongated oligomers assemble into mammalian PrP amyloid fibrils. J Mol Biol (2006) 1.10
Hexameric ring structure of human MCM10 DNA replication factor. EMBO Rep (2007) 1.10
SbsB structure and lattice reconstruction unveil Ca2+ triggered S-layer assembly. Nature (2012) 1.09
Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26. Structure (2006) 1.06
Structure of a bacterial type IV secretion core complex at subnanometre resolution. EMBO J (2013) 1.05
Pilus biogenesis at the outer membrane of Gram-negative bacterial pathogens. Curr Opin Struct Biol (2012) 1.05
The crystal structure of a partial mouse Notch-1 ankyrin domain: repeats 4 through 7 preserve an ankyrin fold. Protein Sci (2005) 1.04
The tyrosine gate as a potential entropic lever in the receptor-binding site of the bacterial adhesin FimH. Biochemistry (2012) 1.04
Rotations of the 2B sub-domain of E. coli UvrD helicase/translocase coupled to nucleotide and DNA binding. J Mol Biol (2011) 1.04
Biochemical dissection of the ATPase TraB, the VirB4 homologue of the Escherichia coli pKM101 conjugation machinery. J Bacteriol (2010) 1.03
Mutant alpha-latrotoxin (LTXN4C) does not form pores and causes secretion by receptor stimulation: this action does not require neurexins. J Biol Chem (2003) 1.02
Crystal structure of the Haemophilus influenzae Hap adhesin reveals an intercellular oligomerization mechanism for bacterial aggregation. EMBO J (2011) 1.01
4.6A Cryo-EM reconstruction of tobacco mosaic virus from images recorded at 300 keV on a 4k x 4k CCD camera. J Struct Biol (2010) 1.00
Molecular characterization of Bacillus pasteurii UreE, a metal-binding chaperone for the assembly of the urease active site. J Biol Inorg Chem (2002) 0.99
Dimerization and interactions of Brucella suis VirB8 with VirB4 and VirB10 are required for its biological activity. Proc Natl Acad Sci U S A (2006) 0.98
Structure of triglyceride-rich human low-density lipoproteins according to cryoelectron microscopy. Biochemistry (2003) 0.98
An intramolecular FRET system monitors fingers subdomain opening in Klentaq1. Protein Sci (2008) 0.98
Donor-strand exchange in chaperone-assisted pilus assembly revealed in atomic detail by molecular dynamics. J Mol Biol (2007) 0.97
Structural insights into Helicobacter pylori oncoprotein CagA interaction with β1 integrin. Proc Natl Acad Sci U S A (2012) 0.97
Structural Biology of Bacterial Type IV Secretion Systems. Annu Rev Biochem (2015) 0.97
Structural biology of the p53 tumour suppressor. Curr Opin Struct Biol (2009) 0.96
Crystal structure of the anticoagulant slow form of thrombin. J Biol Chem (2002) 0.96
A bacterial glycosidase enables mannose-6-phosphate modification and improved cellular uptake of yeast-produced recombinant human lysosomal enzymes. Nat Biotechnol (2012) 0.96
Structure of the hDmc1-ssDNA filament reveals the principles of its architecture. PLoS One (2010) 0.95