Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement.
|
Circulation
|
2005
|
43.74
|
2
|
Biological, clinical and population relevance of 95 loci for blood lipids.
|
Nature
|
2010
|
28.21
|
3
|
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus.
|
Nature
|
2010
|
12.07
|
4
|
Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
|
Nat Med
|
2013
|
9.44
|
5
|
Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans.
|
J Clin Invest
|
2009
|
7.09
|
6
|
Population analysis of large copy number variants and hotspots of human genetic disease.
|
Am J Hum Genet
|
2009
|
6.79
|
7
|
Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease.
|
Am J Clin Nutr
|
2010
|
4.85
|
8
|
Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.
|
Am J Hum Genet
|
2008
|
3.61
|
9
|
Metabolic origins and clinical significance of LDL heterogeneity.
|
J Lipid Res
|
2002
|
3.23
|
10
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
11
|
Diagnosis and management of the metabolic syndrome. An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Executive summary.
|
Cardiol Rev
|
2006
|
2.99
|
12
|
Phenotypic predictors of response to simvastatin therapy among African-Americans and Caucasians: the Cholesterol and Pharmacogenetics (CAP) Study.
|
Am J Cardiol
|
2006
|
2.94
|
13
|
Common variants associated with plasma triglycerides and risk for coronary artery disease.
|
Nat Genet
|
2013
|
2.92
|
14
|
Is there a simple way to identify insulin-resistant individuals at increased risk of cardiovascular disease?
|
Am J Cardiol
|
2005
|
2.80
|
15
|
Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels.
|
Hum Mol Genet
|
2002
|
2.71
|
16
|
Saturated fat, carbohydrate, and cardiovascular disease.
|
Am J Clin Nutr
|
2010
|
2.46
|
17
|
A statin-dependent QTL for GATM expression is associated with statin-induced myopathy.
|
Nature
|
2013
|
2.46
|
18
|
Genome-wide association of lipid-lowering response to statins in combined study populations.
|
PLoS One
|
2010
|
2.43
|
19
|
American College of Endocrinology position statement on the insulin resistance syndrome.
|
Endocr Pract
|
2003
|
2.42
|
20
|
Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults.
|
Proc Natl Acad Sci U S A
|
2004
|
2.41
|
21
|
Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement.
|
Curr Opin Cardiol
|
2006
|
2.41
|
22
|
HDL measures, particle heterogeneity, proposed nomenclature, and relation to atherosclerotic cardiovascular events.
|
Clin Chem
|
2011
|
2.33
|
23
|
Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges.
|
Nat Rev Drug Discov
|
2007
|
2.32
|
24
|
Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement: Executive Summary.
|
Crit Pathw Cardiol
|
2005
|
2.31
|
25
|
Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia.
|
J Lipid Res
|
2002
|
2.28
|
26
|
Direct determination of lipoprotein particle sizes and concentrations by ion mobility analysis.
|
Clin Chem
|
2008
|
2.27
|
27
|
Differential effects of ramipril on ambulatory blood pressure in African Americans and Caucasians.
|
Am J Hypertens
|
2007
|
2.06
|
28
|
Pharmacogenomics: challenges and opportunities.
|
Ann Intern Med
|
2006
|
1.96
|
29
|
Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replication.
|
Circ Cardiovasc Genet
|
2008
|
1.89
|
30
|
When good drugs go bad.
|
Nature
|
2007
|
1.85
|
31
|
Ion mobility analysis of lipoprotein subfractions identifies three independent axes of cardiovascular risk.
|
Arterioscler Thromb Vasc Biol
|
2009
|
1.83
|
32
|
A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma.
|
J Lipid Res
|
2008
|
1.79
|
33
|
Genetic variation in PNPLA3 but not APOC3 influences liver fat in non-alcoholic fatty liver disease.
|
J Gastroenterol Hepatol
|
2012
|
1.67
|
34
|
The role of reducing intakes of saturated fat in the prevention of cardiovascular disease: where does the evidence stand in 2010?
|
Am J Clin Nutr
|
2011
|
1.66
|
35
|
Alternative splicing of 3-hydroxy-3-methylglutaryl coenzyme A reductase is associated with plasma low-density lipoprotein cholesterol response to simvastatin.
|
Circulation
|
2008
|
1.64
|
36
|
Tracing sub-structure in the European American population with PCA-informative markers.
|
PLoS Genet
|
2008
|
1.56
|
37
|
RHOA is a modulator of the cholesterol-lowering effects of statin.
|
PLoS Genet
|
2012
|
1.54
|
38
|
Replication of association of DENND1A and THADA variants with polycystic ovary syndrome in European cohorts.
|
J Med Genet
|
2011
|
1.51
|
39
|
High-density lipoproteins: a consensus statement from the National Lipid Association.
|
J Clin Lipidol
|
2013
|
1.50
|
40
|
A reappraisal of the impact of dairy foods and milk fat on cardiovascular disease risk.
|
Eur J Nutr
|
2009
|
1.38
|
41
|
Consumption of fructose-sweetened beverages for 10 weeks increases postprandial triacylglycerol and apolipoprotein-B concentrations in overweight and obese women.
|
Br J Nutr
|
2008
|
1.38
|
42
|
Determination and use of haplotypes: ethnic comparison and association of the lipoprotein lipase gene and coronary artery disease in Mexican-Americans.
|
Genet Med
|
2003
|
1.38
|
43
|
Enteric microbiome metabolites correlate with response to simvastatin treatment.
|
PLoS One
|
2011
|
1.31
|
44
|
Lipidomic analysis of variation in response to simvastatin in the Cholesterol and Pharmacogenetics Study.
|
Metabolomics
|
2010
|
1.29
|
45
|
Reversal of small, dense LDL subclass phenotype by normalization of adiposity.
|
Obesity (Silver Spring)
|
2009
|
1.28
|
46
|
Structural basis of transfer between lipoproteins by cholesteryl ester transfer protein.
|
Nat Chem Biol
|
2012
|
1.27
|
47
|
Saturated fatty acids and risk of coronary heart disease: modulation by replacement nutrients.
|
Curr Atheroscler Rep
|
2010
|
1.23
|
48
|
A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT.
|
Pharmacogenet Genomics
|
2012
|
1.23
|
49
|
Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment.
|
PLoS One
|
2012
|
1.22
|
50
|
Protein in optimal health: heart disease and type 2 diabetes.
|
Am J Clin Nutr
|
2008
|
1.22
|
51
|
Altered activities of anti-atherogenic enzymes LCAT, paraoxonase, and platelet-activating factor acetylhydrolase in atherosclerosis-susceptible mice.
|
J Lipid Res
|
2002
|
1.19
|
52
|
Combined influence of LDLR and HMGCR sequence variation on lipid-lowering response to simvastatin.
|
Arterioscler Thromb Vasc Biol
|
2010
|
1.19
|
53
|
Smallest LDL particles are most strongly related to coronary disease progression in men.
|
Arterioscler Thromb Vasc Biol
|
2003
|
1.17
|
54
|
Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins.
|
Proc Natl Acad Sci U S A
|
2008
|
1.15
|
55
|
Coordinately regulated alternative splicing of genes involved in cholesterol biosynthesis and uptake.
|
PLoS One
|
2011
|
1.14
|
56
|
Use of an electronic medical record to characterize cases of intermediate statin-induced muscle toxicity.
|
Prev Cardiol
|
2009
|
1.11
|
57
|
Hepatic nuclear factor 1-alpha: inflammation, genetics, and atherosclerosis.
|
Curr Opin Lipidol
|
2009
|
1.09
|
58
|
Characterization of low-density lipoprotein cholesterol-lowering efficacy for atorvastatin in a population-based DNA biorepository.
|
Basic Clin Pharmacol Toxicol
|
2008
|
1.09
|
59
|
VLDL hydrolysis by LPL activates PPAR-alpha through generation of unbound fatty acids.
|
J Lipid Res
|
2010
|
1.08
|
60
|
Individualized hormone-replacement therapy?
|
N Engl J Med
|
2002
|
1.08
|
61
|
Association of the APOLIPOPROTEIN A1/C3/A4/A5 gene cluster with triglyceride levels and LDL particle size in familial combined hyperlipidemia.
|
Circ Res
|
2004
|
1.07
|
62
|
Cardiovascular pharmacogenomics.
|
Circ Res
|
2011
|
1.03
|
63
|
Genome-wide association and pharmacological profiling of 29 anticancer agents using lymphoblastoid cell lines.
|
Pharmacogenomics
|
2014
|
1.00
|
64
|
Role of CYP27A in cholesterol and bile acid metabolism.
|
J Lipid Res
|
2004
|
0.99
|
65
|
Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
|
PLoS One
|
2012
|
0.98
|
66
|
Pharmacogenomics of statin response.
|
Curr Opin Mol Ther
|
2008
|
0.97
|
67
|
Association between angiotensinogen, angiotensin II receptor genes, and blood pressure response to an angiotensin-converting enzyme inhibitor.
|
Circulation
|
2007
|
0.97
|
68
|
Multivariate methods and software for association mapping in dose-response genome-wide association studies.
|
BioData Min
|
2012
|
0.96
|
69
|
Low-density lipoprotein particle size loci in familial combined hyperlipidemia: evidence for multiple loci from a genome scan.
|
Arterioscler Thromb Vasc Biol
|
2004
|
0.96
|
70
|
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function.
|
Hum Mol Genet
|
2013
|
0.96
|
71
|
The role of HMGCR alternative splicing in statin efficacy.
|
Trends Cardiovasc Med
|
2009
|
0.96
|
72
|
Polymorphisms in the peroxisome proliferator activated receptor alpha gene are associated with levels of apolipoprotein CIII and triglyceride in African-Americans but not Caucasians.
|
Atherosclerosis
|
2007
|
0.96
|
73
|
Fatty acid desaturase regulation in adipose tissue by dietary composition is independent of weight loss and is correlated with the plasma triacylglycerol response.
|
Am J Clin Nutr
|
2007
|
0.96
|
74
|
Pharmacogenomics of statin response.
|
Curr Opin Lipidol
|
2007
|
0.95
|
75
|
Changes in lipoprotein(a), oxidized phospholipids, and LDL subclasses with a low-fat high-carbohydrate diet.
|
J Lipid Res
|
2010
|
0.95
|
76
|
ATHENA: a tool for meta-dimensional analysis applied to genotypes and gene expression data to predict HDL cholesterol levels.
|
Pac Symp Biocomput
|
2013
|
0.95
|
77
|
Behavioral versus genetic correlates of lipoproteins and adiposity in identical twins discordant for exercise.
|
Circulation
|
2005
|
0.94
|
78
|
Influence of dietary carbohydrate and fat on LDL and HDL particle distributions.
|
Curr Atheroscler Rep
|
2005
|
0.92
|
79
|
Further investigation in europeans of susceptibility variants for polycystic ovary syndrome discovered in genome-wide association studies of Chinese individuals.
|
J Clin Endocrinol Metab
|
2015
|
0.92
|
80
|
ApoC-III content of apoB-containing lipoproteins is associated with binding to the vascular proteoglycan biglycan.
|
J Lipid Res
|
2002
|
0.91
|
81
|
Haplotypes in the APOA1-C3-A4-A5 gene cluster affect plasma lipids in both humans and baboons.
|
Hum Mol Genet
|
2004
|
0.91
|
82
|
Effects of the PPAR-δ agonist MBX-8025 on atherogenic dyslipidemia.
|
Atherosclerosis
|
2011
|
0.91
|
83
|
Levels of cholesterol in small LDL particles predict atherosclerosis progression and incident CHD in the HDL-Atherosclerosis Treatment Study (HATS).
|
PLoS One
|
2013
|
0.90
|
84
|
Apolipoprotein CIII bound to apoB-containing lipoproteins is associated with small, dense LDL independent of plasma triglyceride levels in healthy men.
|
Atherosclerosis
|
2010
|
0.89
|
85
|
Genetic nondiscrimination legislation: a critical prerequisite for pharmacogenomics data sharing.
|
Pharmacogenomics
|
2007
|
0.89
|
86
|
High disaccharide intake associates with atherogenic lipoprotein profile.
|
Br J Nutr
|
2011
|
0.89
|
87
|
Saturated Fats Versus Polyunsaturated Fats Versus Carbohydrates for Cardiovascular Disease Prevention and Treatment.
|
Annu Rev Nutr
|
2015
|
0.87
|
88
|
A nutrient-dense, high-fiber, fruit-based supplement bar increases HDL cholesterol, particularly large HDL, lowers homocysteine, and raises glutathione in a 2-wk trial.
|
FASEB J
|
2012
|
0.86
|
89
|
A gene score of nine LDL and HDL regulating genes is associated with fluvastatin-induced cholesterol changes in women.
|
J Lipid Res
|
2009
|
0.86
|
90
|
MBX-8025, a novel peroxisome proliferator receptor-delta agonist: lipid and other metabolic effects in dyslipidemic overweight patients treated with and without atorvastatin.
|
J Clin Endocrinol Metab
|
2011
|
0.85
|
91
|
Metabolic effects of nandrolone decanoate and resistance training in men with HIV.
|
Am J Physiol Endocrinol Metab
|
2002
|
0.85
|
92
|
Endurance training has little effect on active muscle free fatty acid, lipoprotein cholesterol, or triglyceride net balances.
|
Am J Physiol Endocrinol Metab
|
2006
|
0.84
|
93
|
Analysis of polymorphisms in the 3' untranslated region of the LDL receptor gene and their effect on plasma cholesterol levels and drug response.
|
Int J Mol Med
|
2008
|
0.84
|
94
|
Statin-induced changes in gene expression in EBV-transformed and native B-cells.
|
Hum Mol Genet
|
2013
|
0.83
|
95
|
Changes in atherogenic dyslipidemia induced by carbohydrate restriction in men are dependent on dietary protein source.
|
J Nutr
|
2011
|
0.83
|
96
|
Metabolic and cardiovascular genes in polycystic ovary syndrome: a candidate-wide association study (CWAS).
|
Steroids
|
2011
|
0.83
|
97
|
Properties of triglyceride-rich and cholesterol-rich lipoproteins in the remnant-like particle fraction of human blood plasma.
|
J Lipid Res
|
2002
|
0.82
|
98
|
CYP3A4*22 and CYP3A5*3 are associated with increased levels of plasma simvastatin concentrations in the cholesterol and pharmacogenetics study cohort.
|
Pharmacogenet Genomics
|
2014
|
0.82
|
99
|
Plasma clearance of human low-density lipoprotein in human apolipoprotein B transgenic mice is related to particle diameter.
|
Metabolism
|
2004
|
0.81
|
100
|
Concordant lipoprotein and weight responses to dietary fat change in identical twins with divergent exercise levels 1.
|
Am J Clin Nutr
|
2005
|
0.81
|
101
|
Is the size of low-density lipoprotein particles related to the risk of coronary heart disease?
|
JAMA
|
2002
|
0.81
|
102
|
Plasma triglyceride concentrations are rapidly reduced following individual bouts of endurance exercise in women.
|
Eur J Appl Physiol
|
2010
|
0.81
|
103
|
Organophosphorus flame retardants inhibit specific liver carboxylesterases and cause serum hypertriglyceridemia.
|
ACS Chem Biol
|
2014
|
0.81
|
104
|
Increased plasma concentrations of lipoprotein(a) during a low-fat, high-carbohydrate diet are associated with increased plasma concentrations of apolipoprotein C-III bound to apolipoprotein B-containing lipoproteins.
|
Am J Clin Nutr
|
2007
|
0.80
|
105
|
Obesity in BSB mice is correlated with expression of genes for iron homeostasis and leptin.
|
Obes Res
|
2004
|
0.80
|
106
|
Acute overactive endocannabinoid signaling induces glucose intolerance, hepatic steatosis, and novel cannabinoid receptor 1 responsive genes.
|
PLoS One
|
2011
|
0.80
|
107
|
Steroidogenic regulatory factor FOS is underexpressed in polycystic ovary syndrome (PCOS) adipose tissue and genetically associated with PCOS susceptibility.
|
J Clin Endocrinol Metab
|
2012
|
0.80
|
108
|
Reversal of small, dense LDL subclass phenotype by weight loss is associated with impaired fat oxidation.
|
Obesity (Silver Spring)
|
2010
|
0.79
|
109
|
Effects of simvastatin, an HMG-CoA reductase inhibitor, in patients with hypertriglyceridemia.
|
Clin Cardiol
|
2003
|
0.79
|
110
|
Low-Density Lipoprotein Particle Number Is Associated With Cardiovascular Events Among Those Not Classified Into Statin Benefit Groups.
|
J Am Coll Cardiol
|
2015
|
0.79
|
111
|
Effects on lipoprotein subclasses of combined expression of human hepatic lipase and human apoB in transgenic rabbits.
|
Arterioscler Thromb Vasc Biol
|
2003
|
0.78
|
112
|
Relationship of sex to diabetes risk in statin trials.
|
Diabetes Care
|
2013
|
0.78
|
113
|
Harnessing expression data to identify novel candidate genes in polycystic ovary syndrome.
|
PLoS One
|
2011
|
0.78
|
114
|
Alternative splicing in the regulation of cholesterol homeostasis.
|
Curr Opin Lipidol
|
2013
|
0.78
|
115
|
CNR1 genotype influences HDL-cholesterol response to change in dietary fat intake.
|
PLoS One
|
2012
|
0.78
|
116
|
Impact of mifepristone, a glucocorticoid/progesterone antagonist, on HDL cholesterol, HDL particle concentration, and HDL function.
|
J Clin Endocrinol Metab
|
2012
|
0.77
|
117
|
Lipid metabolism in children and adolescents: Impact on vascular biology.
|
J Clin Lipidol
|
2008
|
0.77
|
118
|
Nonalcoholic steatohepatitis is associated with an atherogenic lipoprotein subfraction profile.
|
Lipids Health Dis
|
2014
|
0.76
|
119
|
In Memoriam: Alexander V. Nichols (1924 – 2015).
|
J Lipid Res
|
2015
|
0.76
|
120
|
Prediction of LDL cholesterol response to statin using transcriptomic and genetic variation.
|
Genome Biol
|
2014
|
0.76
|
121
|
Analysis and quantitation of biotinylated apoB-containing lipoproteins with streptavidin-Cy3.
|
J Lipid Res
|
2002
|
0.76
|
122
|
Alcohol and the heart: does raising high-density lipoprotein matter?
|
Circulation
|
2011
|
0.76
|
123
|
The editor's roundtable: expanded versus standard lipid panels in assessing and managing cardiovascular risk.
|
Am J Cardiol
|
2008
|
0.76
|
124
|
Ancestry and other genetic associations with plasma PCSK9 response to simvastatin.
|
Pharmacogenet Genomics
|
2014
|
0.76
|
125
|
Insulin resistance syndrome and dyslipidemia.
|
Endocr Pract
|
2003
|
0.76
|
126
|
Individual and Combined Associations of Genetic Variants in CYP3A4, CYP3A5, and SLCO1B1 With Simvastatin and Simvastatin Acid Plasma Concentrations.
|
J Cardiovasc Pharmacol
|
2015
|
0.75
|
127
|
Genetic variation in the UGT1A locus is associated with simvastatin efficacy in a clinical practice setting.
|
Pharmacogenomics
|
2014
|
0.75
|
128
|
Phospholipid transfer protein and atherosclerosis: genetic studies take aim at a moving target.
|
Circulation
|
2010
|
0.75
|
129
|
Energy substrate partitioning and efficiency in individuals with atherogenic lipoprotein phenotype.
|
Obesity (Silver Spring)
|
2011
|
0.75
|
130
|
PharmGKB summary: very important pharmacogene information for RYR1.
|
Pharmacogenet Genomics
|
2016
|
0.75
|
131
|
Diet, lipids, and cardiovascular disease.
|
Curr Opin Lipidol
|
2016
|
0.75
|