Ronald M Krauss

Author PubWeight™ 268.37‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005 43.74
2 Biological, clinical and population relevance of 95 loci for blood lipids. Nature 2010 28.21
3 From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus. Nature 2010 12.07
4 Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis. Nat Med 2013 9.44
5 Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans. J Clin Invest 2009 7.09
6 Population analysis of large copy number variants and hotspots of human genetic disease. Am J Hum Genet 2009 6.79
7 Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease. Am J Clin Nutr 2010 4.85
8 Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein. Am J Hum Genet 2008 3.61
9 Metabolic origins and clinical significance of LDL heterogeneity. J Lipid Res 2002 3.23
10 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
11 Diagnosis and management of the metabolic syndrome. An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Executive summary. Cardiol Rev 2006 2.99
12 Phenotypic predictors of response to simvastatin therapy among African-Americans and Caucasians: the Cholesterol and Pharmacogenetics (CAP) Study. Am J Cardiol 2006 2.94
13 Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet 2013 2.92
14 Is there a simple way to identify insulin-resistant individuals at increased risk of cardiovascular disease? Am J Cardiol 2005 2.80
15 Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels. Hum Mol Genet 2002 2.71
16 Saturated fat, carbohydrate, and cardiovascular disease. Am J Clin Nutr 2010 2.46
17 A statin-dependent QTL for GATM expression is associated with statin-induced myopathy. Nature 2013 2.46
18 Genome-wide association of lipid-lowering response to statins in combined study populations. PLoS One 2010 2.43
19 American College of Endocrinology position statement on the insulin resistance syndrome. Endocr Pract 2003 2.42
20 Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults. Proc Natl Acad Sci U S A 2004 2.41
21 Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement. Curr Opin Cardiol 2006 2.41
22 HDL measures, particle heterogeneity, proposed nomenclature, and relation to atherosclerotic cardiovascular events. Clin Chem 2011 2.33
23 Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges. Nat Rev Drug Discov 2007 2.32
24 Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement: Executive Summary. Crit Pathw Cardiol 2005 2.31
25 Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia. J Lipid Res 2002 2.28
26 Direct determination of lipoprotein particle sizes and concentrations by ion mobility analysis. Clin Chem 2008 2.27
27 Differential effects of ramipril on ambulatory blood pressure in African Americans and Caucasians. Am J Hypertens 2007 2.06
28 Pharmacogenomics: challenges and opportunities. Ann Intern Med 2006 1.96
29 Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replication. Circ Cardiovasc Genet 2008 1.89
30 When good drugs go bad. Nature 2007 1.85
31 Ion mobility analysis of lipoprotein subfractions identifies three independent axes of cardiovascular risk. Arterioscler Thromb Vasc Biol 2009 1.83
32 A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma. J Lipid Res 2008 1.79
33 Genetic variation in PNPLA3 but not APOC3 influences liver fat in non-alcoholic fatty liver disease. J Gastroenterol Hepatol 2012 1.67
34 The role of reducing intakes of saturated fat in the prevention of cardiovascular disease: where does the evidence stand in 2010? Am J Clin Nutr 2011 1.66
35 Alternative splicing of 3-hydroxy-3-methylglutaryl coenzyme A reductase is associated with plasma low-density lipoprotein cholesterol response to simvastatin. Circulation 2008 1.64
36 Tracing sub-structure in the European American population with PCA-informative markers. PLoS Genet 2008 1.56
37 RHOA is a modulator of the cholesterol-lowering effects of statin. PLoS Genet 2012 1.54
38 Replication of association of DENND1A and THADA variants with polycystic ovary syndrome in European cohorts. J Med Genet 2011 1.51
39 High-density lipoproteins: a consensus statement from the National Lipid Association. J Clin Lipidol 2013 1.50
40 A reappraisal of the impact of dairy foods and milk fat on cardiovascular disease risk. Eur J Nutr 2009 1.38
41 Consumption of fructose-sweetened beverages for 10 weeks increases postprandial triacylglycerol and apolipoprotein-B concentrations in overweight and obese women. Br J Nutr 2008 1.38
42 Determination and use of haplotypes: ethnic comparison and association of the lipoprotein lipase gene and coronary artery disease in Mexican-Americans. Genet Med 2003 1.38
43 Enteric microbiome metabolites correlate with response to simvastatin treatment. PLoS One 2011 1.31
44 Lipidomic analysis of variation in response to simvastatin in the Cholesterol and Pharmacogenetics Study. Metabolomics 2010 1.29
45 Reversal of small, dense LDL subclass phenotype by normalization of adiposity. Obesity (Silver Spring) 2009 1.28
46 Structural basis of transfer between lipoproteins by cholesteryl ester transfer protein. Nat Chem Biol 2012 1.27
47 Saturated fatty acids and risk of coronary heart disease: modulation by replacement nutrients. Curr Atheroscler Rep 2010 1.23
48 A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT. Pharmacogenet Genomics 2012 1.23
49 Metabolomics reveals amino acids contribute to variation in response to simvastatin treatment. PLoS One 2012 1.22
50 Protein in optimal health: heart disease and type 2 diabetes. Am J Clin Nutr 2008 1.22
51 Altered activities of anti-atherogenic enzymes LCAT, paraoxonase, and platelet-activating factor acetylhydrolase in atherosclerosis-susceptible mice. J Lipid Res 2002 1.19
52 Combined influence of LDLR and HMGCR sequence variation on lipid-lowering response to simvastatin. Arterioscler Thromb Vasc Biol 2010 1.19
53 Smallest LDL particles are most strongly related to coronary disease progression in men. Arterioscler Thromb Vasc Biol 2003 1.17
54 Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins. Proc Natl Acad Sci U S A 2008 1.15
55 Coordinately regulated alternative splicing of genes involved in cholesterol biosynthesis and uptake. PLoS One 2011 1.14
56 Use of an electronic medical record to characterize cases of intermediate statin-induced muscle toxicity. Prev Cardiol 2009 1.11
57 Hepatic nuclear factor 1-alpha: inflammation, genetics, and atherosclerosis. Curr Opin Lipidol 2009 1.09
58 Characterization of low-density lipoprotein cholesterol-lowering efficacy for atorvastatin in a population-based DNA biorepository. Basic Clin Pharmacol Toxicol 2008 1.09
59 VLDL hydrolysis by LPL activates PPAR-alpha through generation of unbound fatty acids. J Lipid Res 2010 1.08
60 Individualized hormone-replacement therapy? N Engl J Med 2002 1.08
61 Association of the APOLIPOPROTEIN A1/C3/A4/A5 gene cluster with triglyceride levels and LDL particle size in familial combined hyperlipidemia. Circ Res 2004 1.07
62 Cardiovascular pharmacogenomics. Circ Res 2011 1.03
63 Genome-wide association and pharmacological profiling of 29 anticancer agents using lymphoblastoid cell lines. Pharmacogenomics 2014 1.00
64 Role of CYP27A in cholesterol and bile acid metabolism. J Lipid Res 2004 0.99
65 Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project. PLoS One 2012 0.98
66 Pharmacogenomics of statin response. Curr Opin Mol Ther 2008 0.97
67 Association between angiotensinogen, angiotensin II receptor genes, and blood pressure response to an angiotensin-converting enzyme inhibitor. Circulation 2007 0.97
68 Multivariate methods and software for association mapping in dose-response genome-wide association studies. BioData Min 2012 0.96
69 Low-density lipoprotein particle size loci in familial combined hyperlipidemia: evidence for multiple loci from a genome scan. Arterioscler Thromb Vasc Biol 2004 0.96
70 A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function. Hum Mol Genet 2013 0.96
71 The role of HMGCR alternative splicing in statin efficacy. Trends Cardiovasc Med 2009 0.96
72 Polymorphisms in the peroxisome proliferator activated receptor alpha gene are associated with levels of apolipoprotein CIII and triglyceride in African-Americans but not Caucasians. Atherosclerosis 2007 0.96
73 Fatty acid desaturase regulation in adipose tissue by dietary composition is independent of weight loss and is correlated with the plasma triacylglycerol response. Am J Clin Nutr 2007 0.96
74 Pharmacogenomics of statin response. Curr Opin Lipidol 2007 0.95
75 Changes in lipoprotein(a), oxidized phospholipids, and LDL subclasses with a low-fat high-carbohydrate diet. J Lipid Res 2010 0.95
76 ATHENA: a tool for meta-dimensional analysis applied to genotypes and gene expression data to predict HDL cholesterol levels. Pac Symp Biocomput 2013 0.95
77 Behavioral versus genetic correlates of lipoproteins and adiposity in identical twins discordant for exercise. Circulation 2005 0.94
78 Influence of dietary carbohydrate and fat on LDL and HDL particle distributions. Curr Atheroscler Rep 2005 0.92
79 Further investigation in europeans of susceptibility variants for polycystic ovary syndrome discovered in genome-wide association studies of Chinese individuals. J Clin Endocrinol Metab 2015 0.92
80 ApoC-III content of apoB-containing lipoproteins is associated with binding to the vascular proteoglycan biglycan. J Lipid Res 2002 0.91
81 Haplotypes in the APOA1-C3-A4-A5 gene cluster affect plasma lipids in both humans and baboons. Hum Mol Genet 2004 0.91
82 Effects of the PPAR-δ agonist MBX-8025 on atherogenic dyslipidemia. Atherosclerosis 2011 0.91
83 Levels of cholesterol in small LDL particles predict atherosclerosis progression and incident CHD in the HDL-Atherosclerosis Treatment Study (HATS). PLoS One 2013 0.90
84 Apolipoprotein CIII bound to apoB-containing lipoproteins is associated with small, dense LDL independent of plasma triglyceride levels in healthy men. Atherosclerosis 2010 0.89
85 Genetic nondiscrimination legislation: a critical prerequisite for pharmacogenomics data sharing. Pharmacogenomics 2007 0.89
86 High disaccharide intake associates with atherogenic lipoprotein profile. Br J Nutr 2011 0.89
87 Saturated Fats Versus Polyunsaturated Fats Versus Carbohydrates for Cardiovascular Disease Prevention and Treatment. Annu Rev Nutr 2015 0.87
88 A nutrient-dense, high-fiber, fruit-based supplement bar increases HDL cholesterol, particularly large HDL, lowers homocysteine, and raises glutathione in a 2-wk trial. FASEB J 2012 0.86
89 A gene score of nine LDL and HDL regulating genes is associated with fluvastatin-induced cholesterol changes in women. J Lipid Res 2009 0.86
90 MBX-8025, a novel peroxisome proliferator receptor-delta agonist: lipid and other metabolic effects in dyslipidemic overweight patients treated with and without atorvastatin. J Clin Endocrinol Metab 2011 0.85
91 Metabolic effects of nandrolone decanoate and resistance training in men with HIV. Am J Physiol Endocrinol Metab 2002 0.85
92 Endurance training has little effect on active muscle free fatty acid, lipoprotein cholesterol, or triglyceride net balances. Am J Physiol Endocrinol Metab 2006 0.84
93 Analysis of polymorphisms in the 3' untranslated region of the LDL receptor gene and their effect on plasma cholesterol levels and drug response. Int J Mol Med 2008 0.84
94 Statin-induced changes in gene expression in EBV-transformed and native B-cells. Hum Mol Genet 2013 0.83
95 Changes in atherogenic dyslipidemia induced by carbohydrate restriction in men are dependent on dietary protein source. J Nutr 2011 0.83
96 Metabolic and cardiovascular genes in polycystic ovary syndrome: a candidate-wide association study (CWAS). Steroids 2011 0.83
97 Properties of triglyceride-rich and cholesterol-rich lipoproteins in the remnant-like particle fraction of human blood plasma. J Lipid Res 2002 0.82
98 CYP3A4*22 and CYP3A5*3 are associated with increased levels of plasma simvastatin concentrations in the cholesterol and pharmacogenetics study cohort. Pharmacogenet Genomics 2014 0.82
99 Plasma clearance of human low-density lipoprotein in human apolipoprotein B transgenic mice is related to particle diameter. Metabolism 2004 0.81
100 Concordant lipoprotein and weight responses to dietary fat change in identical twins with divergent exercise levels 1. Am J Clin Nutr 2005 0.81
101 Is the size of low-density lipoprotein particles related to the risk of coronary heart disease? JAMA 2002 0.81
102 Plasma triglyceride concentrations are rapidly reduced following individual bouts of endurance exercise in women. Eur J Appl Physiol 2010 0.81
103 Organophosphorus flame retardants inhibit specific liver carboxylesterases and cause serum hypertriglyceridemia. ACS Chem Biol 2014 0.81
104 Increased plasma concentrations of lipoprotein(a) during a low-fat, high-carbohydrate diet are associated with increased plasma concentrations of apolipoprotein C-III bound to apolipoprotein B-containing lipoproteins. Am J Clin Nutr 2007 0.80
105 Obesity in BSB mice is correlated with expression of genes for iron homeostasis and leptin. Obes Res 2004 0.80
106 Acute overactive endocannabinoid signaling induces glucose intolerance, hepatic steatosis, and novel cannabinoid receptor 1 responsive genes. PLoS One 2011 0.80
107 Steroidogenic regulatory factor FOS is underexpressed in polycystic ovary syndrome (PCOS) adipose tissue and genetically associated with PCOS susceptibility. J Clin Endocrinol Metab 2012 0.80
108 Reversal of small, dense LDL subclass phenotype by weight loss is associated with impaired fat oxidation. Obesity (Silver Spring) 2010 0.79
109 Effects of simvastatin, an HMG-CoA reductase inhibitor, in patients with hypertriglyceridemia. Clin Cardiol 2003 0.79
110 Low-Density Lipoprotein Particle Number Is Associated With Cardiovascular Events Among Those Not Classified Into Statin Benefit Groups. J Am Coll Cardiol 2015 0.79
111 Effects on lipoprotein subclasses of combined expression of human hepatic lipase and human apoB in transgenic rabbits. Arterioscler Thromb Vasc Biol 2003 0.78
112 Relationship of sex to diabetes risk in statin trials. Diabetes Care 2013 0.78
113 Harnessing expression data to identify novel candidate genes in polycystic ovary syndrome. PLoS One 2011 0.78
114 Alternative splicing in the regulation of cholesterol homeostasis. Curr Opin Lipidol 2013 0.78
115 CNR1 genotype influences HDL-cholesterol response to change in dietary fat intake. PLoS One 2012 0.78
116 Impact of mifepristone, a glucocorticoid/progesterone antagonist, on HDL cholesterol, HDL particle concentration, and HDL function. J Clin Endocrinol Metab 2012 0.77
117 Lipid metabolism in children and adolescents: Impact on vascular biology. J Clin Lipidol 2008 0.77
118 Nonalcoholic steatohepatitis is associated with an atherogenic lipoprotein subfraction profile. Lipids Health Dis 2014 0.76
119 In Memoriam: Alexander V. Nichols (1924 – 2015). J Lipid Res 2015 0.76
120 Prediction of LDL cholesterol response to statin using transcriptomic and genetic variation. Genome Biol 2014 0.76
121 Analysis and quantitation of biotinylated apoB-containing lipoproteins with streptavidin-Cy3. J Lipid Res 2002 0.76
122 Alcohol and the heart: does raising high-density lipoprotein matter? Circulation 2011 0.76
123 The editor's roundtable: expanded versus standard lipid panels in assessing and managing cardiovascular risk. Am J Cardiol 2008 0.76
124 Ancestry and other genetic associations with plasma PCSK9 response to simvastatin. Pharmacogenet Genomics 2014 0.76
125 Insulin resistance syndrome and dyslipidemia. Endocr Pract 2003 0.76
126 Individual and Combined Associations of Genetic Variants in CYP3A4, CYP3A5, and SLCO1B1 With Simvastatin and Simvastatin Acid Plasma Concentrations. J Cardiovasc Pharmacol 2015 0.75
127 Genetic variation in the UGT1A locus is associated with simvastatin efficacy in a clinical practice setting. Pharmacogenomics 2014 0.75
128 Phospholipid transfer protein and atherosclerosis: genetic studies take aim at a moving target. Circulation 2010 0.75
129 Energy substrate partitioning and efficiency in individuals with atherogenic lipoprotein phenotype. Obesity (Silver Spring) 2011 0.75
130 PharmGKB summary: very important pharmacogene information for RYR1. Pharmacogenet Genomics 2016 0.75
131 Diet, lipids, and cardiovascular disease. Curr Opin Lipidol 2016 0.75