Published in BMJ on January 20, 2010
Devolution and divergence in UK health policies. BMJ (2008) 1.72
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
A new multipoint method for genome-wide association studies by imputation of genotypes. Nat Genet (2007) 52.68
A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet (2009) 30.09
A fine-scale map of recombination rates and hotspots across the human genome. Science (2005) 26.82
A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet (2003) 26.59
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
The fine-scale structure of recombination rate variation in the human genome. Science (2004) 17.05
Replicating genotype-phenotype associations. Nature (2007) 16.11
The effects of human population structure on large genetic association studies. Nat Genet (2004) 14.88
Genome-wide strategies for detecting multiple loci that influence complex diseases. Nat Genet (2005) 14.88
New models of collaboration in genome-wide association studies: the Genetic Association Information Network. Nat Genet (2007) 13.76
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet (2007) 12.62
A comparison of phasing algorithms for trios and unrelated individuals. Am J Hum Genet (2006) 12.45
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
Transcriptome and genome sequencing uncovers functional variation in humans. Nature (2013) 8.89
A common sequence motif associated with recombination hot spots and genome instability in humans. Nat Genet (2008) 8.64
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet (2010) 8.48
Comparison of fine-scale recombination rates in humans and chimpanzees. Science (2005) 7.86
Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet (2013) 7.44
Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination. Science (2009) 7.35
Designing genome-wide association studies: sample size, power, imputation, and the choice of genotyping chip. PLoS Genet (2009) 6.61
Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas. Nat Genet (2012) 6.25
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nat Genet (2011) 5.56
Accessibility, sustainability, excellence: how to expand access to research publications. Executive summary. Int Microbiol (2013) 4.66
A statistical method for predicting classical HLA alleles from SNP data. Am J Hum Genet (2008) 4.65
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet (2013) 4.62
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat Genet (2009) 4.61
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nat Genet (2010) 4.42
Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet (2009) 4.30
The influence of recombination on human genetic diversity. PLoS Genet (2006) 4.04
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet (2012) 3.40
Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21. Hum Mol Genet (2010) 3.34
Human recombination hot spots hidden in regions of strong marker association. Nat Genet (2005) 3.33
Bayesian refinement of association signals for 14 loci in 3 common diseases. Nat Genet (2012) 3.31
Evolutionary dynamics of Staphylococcus aureus during progression from carriage to disease. Proc Natl Acad Sci U S A (2012) 3.29
Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci. Nat Genet (2013) 2.87
A fine-scale chimpanzee genetic map from population sequencing. Science (2012) 2.83
Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer. Nature (2012) 2.66
HAPGEN2: simulation of multiple disease SNPs. Bioinformatics (2011) 2.58
Multiple instances of ancient balancing selection shared between humans and chimpanzees. Science (2013) 2.32
A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection. PLoS Genet (2011) 1.83
Is mate choice in humans MHC-dependent? PLoS Genet (2008) 1.66
Including known covariates can reduce power to detect genetic effects in case-control studies. Nat Genet (2012) 1.66
Recombination and population structure in Salmonella enterica. PLoS Genet (2011) 1.61
Human metabolic profiles are stably controlled by genetic and environmental variation. Mol Syst Biol (2011) 1.60
Application of coalescent methods to reveal fine-scale rate variation and recombination hotspots. Genetics (2004) 1.59
People of the British Isles: preliminary analysis of genotypes and surnames in a UK-control population. Eur J Hum Genet (2011) 1.58
Gang membership, violence, and psychiatric morbidity. Am J Psychiatry (2013) 1.54
Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus. Nat Genet (2012) 1.52
Pneumococcal genome sequencing tracks a vaccine escape variant formed through a multi-fragment recombination event. Nat Genet (2012) 1.43
Presynaptic NMDARs in the hippocampus facilitate transmitter release at theta frequency. Neuron (2010) 1.33
Quantifying the underestimation of relative risks from genome-wide association studies. PLoS Genet (2011) 1.30
High recombination rate in herpes simplex virus type 1 natural populations suggests significant co-infection. Infect Genet Evol (2004) 1.23
A robust clustering algorithm for identifying problematic samples in genome-wide association studies. Bioinformatics (2011) 1.19
Congenital myasthenic syndromes due to mutations in ALG2 and ALG14. Brain (2013) 1.18
Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis. Nat Genet (2013) 1.15
Disease model distortion in association studies. Genet Epidemiol (2011) 1.14
Recessive mutations in SPTBN2 implicate β-III spectrin in both cognitive and motor development. PLoS Genet (2012) 1.14
Economic instruments for obesity prevention: results of a scoping review and modified Delphi survey. Int J Behav Nutr Phys Act (2011) 1.05
A model-based approach to capture genetic variation for future association studies. Genome Res (2006) 1.05
Genomic tools for evolution and conservation in the chimpanzee: Pan troglodytes ellioti is a genetically distinct population. PLoS Genet (2012) 1.00
Gene-gene interactions in breast cancer susceptibility. Hum Mol Genet (2011) 0.97
Homozygous mutations in a predicted endonuclease are a novel cause of congenital dyserythropoietic anemia type I. Haematologica (2013) 0.95
Bayesian hierarchical mixture modeling to assign copy number from a targeted CNV array. Genet Epidemiol (2011) 0.93
Patterns of Eurasian HSV-1 molecular diversity and inferences of human migrations. Infect Genet Evol (2005) 0.90
Fatal hemorrhagic pneumonia caused by infection due to Kytococcus sedentarius--a pathogen or passenger? Ann Hematol (2003) 0.88
A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation. Biol Psychiatry (2013) 0.87
Systematic review of validity testing in colonoscopy simulation. Surg Endosc (2012) 0.86
The antimicrobial effect of Iseganan HCl oral solution in patients receiving stomatotoxic chemotherapy: analysis from a multicenter, double-blind, placebo-controlled, randomized, phase III clinical trial. J Oral Pathol Med (2011) 0.85
Effectiveness of an educational video on concussion knowledge in minor league hockey players: a cluster randomised controlled trial. Br J Sports Med (2013) 0.84
Options for early breast cancer follow-up in primary and secondary care - a systematic review. BMC Cancer (2012) 0.84
Experiments with the site frequency spectrum. Bull Math Biol (2010) 0.81
Assessing association between protein truncating variants and quantitative traits. Bioinformatics (2013) 0.78
The role of ATM in response to metformin treatment and activation of AMPK. Nat Genet (2012) 0.77
Polymerase chain reaction blood tests for the diagnosis of invasive aspergillosis in immunocompromised people. Cochrane Database Syst Rev (2015) 0.77
A review of quality assessment of the methodology used in guidelines and systematic reviews on oral mucositis. J Clin Nurs (2009) 0.75
Polymerase chain reaction blood tests for the diagnosis of invasive aspergillosis in immunocompromised people. Cochrane Database Syst Rev (2015) 0.75
Software process improvement for the medical industry. Stud Health Technol Inform (2005) 0.75
A scientific and psychosocial environmental investigation tool: the Meeting, Understanding, Surveillance, Toxicology, Evaluation and Reporting (MUSTER) model. Postgrad Med J (2011) 0.75