PubRank

Josep Rizo

Author PubWeight™ 122.93‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis. Cell 2006 4.36
2 Jasmonate perception by inositol-phosphate-potentiated COI1-JAZ co-receptor. Nature 2010 3.87
3 Three-dimensional structure of the complexin/SNARE complex. Neuron 2002 3.69
4 The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20. Mol Cell 2002 3.24
5 Close membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids. Nat Struct Mol Biol 2006 3.14
6 Munc18-1 binds directly to the neuronal SNARE complex. Proc Natl Acad Sci U S A 2007 3.03
7 RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction. Cell 2011 2.90
8 The Mad2 spindle checkpoint protein has two distinct natively folded states. Nat Struct Mol Biol 2004 2.87
9 A broken alpha -helix in folded alpha -Synuclein. J Biol Chem 2003 2.80
10 Reconstitution of the vital functions of Munc18 and Munc13 in neurotransmitter release. Science 2012 2.70
11 Distinct domains of complexin I differentially regulate neurotransmitter release. Nat Struct Mol Biol 2007 2.63
12 Conformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpoint. EMBO J 2004 2.57
13 Conformational switch of syntaxin-1 controls synaptic vesicle fusion. Science 2008 2.44
14 Sly1 binds to Golgi and ER syntaxins via a conserved N-terminal peptide motif. Dev Cell 2002 2.43
15 How Tlg2p/syntaxin 16 'snares' Vps45. EMBO J 2002 2.31
16 p31comet blocks Mad2 activation through structural mimicry. Cell 2007 2.26
17 Dual modes of Munc18-1/SNARE interactions are coupled by functionally critical binding to syntaxin-1 N terminus. J Neurosci 2007 2.02
18 A conformational switch in the Piccolo C2A domain regulated by alternative splicing. Nat Struct Mol Biol 2003 1.98
19 Synaptic vesicle exocytosis. Cold Spring Harb Perspect Biol 2011 1.97
20 Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex. Nat Struct Mol Biol 2011 1.95
21 Genetic analysis of synaptotagmin 2 in spontaneous and Ca2+-triggered neurotransmitter release. EMBO J 2006 1.93
22 SNARE-mediated lipid mixing depends on the physical state of the vesicles. Biophys J 2005 1.91
23 Structural basis for a Munc13-1 homodimer to Munc13-1/RIM heterodimer switch. PLoS Biol 2006 1.88
24 A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity? EMBO J 2005 1.86
25 A protein sequence that can encode native structure by disfavoring alternate conformations. Nat Struct Biol 2002 1.85
26 Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming. J Cell Biol 2009 1.80
27 The Janus-faced nature of the C(2)B domain is fundamental for synaptotagmin-1 function. Nat Struct Mol Biol 2008 1.76
28 A quaternary SNARE-synaptotagmin-Ca2+-phospholipid complex in neurotransmitter release. J Mol Biol 2007 1.73
29 A minimal domain responsible for Munc13 activity. Nat Struct Mol Biol 2005 1.68
30 Binding of the Munc13-1 MUN domain to membrane-anchored SNARE complexes. Biochemistry 2008 1.67
31 At the junction of SNARE and SM protein function. Curr Opin Cell Biol 2010 1.65
32 Binding of the complexin N terminus to the SNARE complex potentiates synaptic-vesicle fusogenicity. Nat Struct Mol Biol 2010 1.63
33 Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis. Nat Struct Mol Biol 2010 1.58
34 Binding of Munc18-1 to synaptobrevin and to the SNARE four-helix bundle. Biochemistry 2010 1.46
35 Insights into mad2 regulation in the spindle checkpoint revealed by the crystal structure of the symmetric mad2 dimer. PLoS Biol 2008 1.41
36 Convergence and divergence in the mechanism of SNARE binding by Sec1/Munc18-like proteins. Proc Natl Acad Sci U S A 2002 1.37
37 Differential but convergent functions of Ca2+ binding to synaptotagmin-1 C2 domains mediate neurotransmitter release. Proc Natl Acad Sci U S A 2009 1.37
38 Phosphatidylinositol phosphates as co-activators of Ca2+ binding to C2 domains of synaptotagmin 1. J Biol Chem 2006 1.34
39 Calcium binding to PICK1 is essential for the intracellular retention of AMPA receptors underlying long-term depression. J Neurosci 2010 1.34
40 Structure/function analysis of Ca2+ binding to the C2A domain of synaptotagmin 1. J Neurosci 2002 1.32
41 The crystal structure of a Munc13 C-terminal module exhibits a remarkable similarity to vesicle tethering factors. Structure 2011 1.32
42 NMR structures of the selenoproteins Sep15 and SelM reveal redox activity of a new thioredoxin-like family. J Biol Chem 2005 1.29
43 Genetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosis. Proc Natl Acad Sci U S A 2008 1.29
44 Structural basis for the evolutionary inactivation of Ca2+ binding to synaptotagmin 4. Nat Struct Mol Biol 2004 1.26
45 Facile detection of protein-protein interactions by one-dimensional NMR spectroscopy. Biochemistry 2003 1.25
46 Synaptotagmin function in dense core vesicle exocytosis studied in cracked PC12 cells. Nat Neurosci 2002 1.25
47 The N-terminal domains of syntaxin 7 and vti1b form three-helix bundles that differ in their ability to regulate SNARE complex assembly. J Biol Chem 2002 1.25
48 Remote homology between Munc13 MUN domain and vesicle tethering complexes. J Mol Biol 2009 1.24
49 NMR analysis of the closed conformation of syntaxin-1. J Biomol NMR 2008 1.19
50 Structural analysis of conserved oligomeric Golgi complex subunit 2. J Biol Chem 2007 1.15
51 Complexin/synaptotagmin interplay controls acrosomal exocytosis. J Biol Chem 2007 1.15
52 Rabphilin regulates SNARE-dependent re-priming of synaptic vesicles for fusion. EMBO J 2006 1.11
53 Solution structure of the Vam7p PX domain. Biochemistry 2002 1.10
54 Reluctance to membrane binding enables accessibility of the synaptobrevin SNARE motif for SNARE complex formation. Proc Natl Acad Sci U S A 2011 1.04
55 Evidence for SNARE zippering during Ca2+-triggered exocytosis in PC12 cells. Neuropharmacology 2003 0.99
56 Endocytosis of synaptotagmin 1 is mediated by a novel, tryptophan-containing motif. Traffic 2003 0.97
57 Three-dimensional structure of the rSly1 N-terminal domain reveals a conformational change induced by binding to syntaxin 5. J Mol Biol 2004 0.96
58 Intramolecular occlusion of the diacylglycerol-binding site in the C1 domain of munc13-1. Biochemistry 2005 0.94
59 Role of electrostatic and hydrophobic interactions in Ca(2+)-dependent phospholipid binding by the C(2)A-domain from synaptotagmin I. Diabetes 2002 0.94
60 Subtle Interplay between synaptotagmin and complexin binding to the SNARE complex. J Mol Biol 2013 0.94
61 Three-dimensional structure of an independently folded extracellular domain of human amyloid-beta precursor protein. Biochemistry 2004 0.92
62 NMR structure and calcium-binding properties of the tellurite resistance protein TerD from Klebsiella pneumoniae. J Mol Biol 2010 0.92
63 Prevalent mechanism of membrane bridging by synaptotagmin-1. Proc Natl Acad Sci U S A 2013 0.90
64 Membrane bridging and hemifusion by denaturated Munc18. PLoS One 2011 0.89
65 Crystal structure of the RIM2 C2A-domain at 1.4 A resolution. Biochemistry 2005 0.89
66 Are neuronal SNARE proteins Ca2+ sensors? J Mol Biol 2005 0.88
67 Solution structure of the RIM1alpha PDZ domain in complex with an ELKS1b C-terminal peptide. J Mol Biol 2005 0.87
68 SNARE function revisited. Nat Struct Biol 2003 0.86
69 Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7. PLoS One 2010 0.85
70 Analysis of SNARE complex/synaptotagmin-1 interactions by one-dimensional NMR spectroscopy. Biochemistry 2013 0.85
71 Unexpected Ca2+-binding properties of synaptotagmin 9. Proc Natl Acad Sci U S A 2004 0.84
72 Autoinhibition of Mint1 adaptor protein regulates amyloid precursor protein binding and processing. Proc Natl Acad Sci U S A 2012 0.84
73 NMR measurement of the off rate from the first calcium-binding site of the synaptotagmin I C2A domain. FEBS Lett 2002 0.83
74 Crystal structure of the RIM1alpha C2B domain at 1.7 A resolution. Biochemistry 2007 0.83
75 How much can SNAREs flex their muscles? Nat Struct Mol Biol 2007 0.82
76 Synaptotagmin-SNARE coupling enlightened. Nat Struct Mol Biol 2010 0.80
77 A dynamic t-SNARE complex. Structure 2008 0.79
78 Bimodal-hybrid heterocyclic amine targeting oxidative pathways and copper mis-regulation in Alzheimer's disease. Metallomics 2014 0.75