PubRank

Tom A Rapoport

Author PubWeight™ 147.12‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 X-ray structure of a protein-conducting channel. Nature 2003 9.20
2 A class of membrane proteins shaping the tubular endoplasmic reticulum. Cell 2006 8.53
3 A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Nature 2004 6.37
4 Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins. Cell 2006 5.54
5 Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains. J Cell Biol 2003 4.35
6 Retro-translocation of proteins from the endoplasmic reticulum into the cytosol. Nat Rev Mol Cell Biol 2002 4.29
7 Mathematical models of protein kinase signal transduction. Mol Cell 2002 4.08
8 A class of dynamin-like GTPases involved in the generation of the tubular ER network. Cell 2009 3.88
9 Structure of a complex of the ATPase SecA and the protein-translocation channel. Nature 2008 3.73
10 Membrane proteins of the endoplasmic reticulum induce high-curvature tubules. Science 2008 3.60
11 Mechanisms determining the morphology of the peripheral ER. Cell 2010 3.35
12 Structural organization of the endoplasmic reticulum. EMBO Rep 2002 3.25
13 The reticulon and DP1/Yop1p proteins form immobile oligomers in the tubular endoplasmic reticulum. J Biol Chem 2008 3.13
14 Protein translocation by the Sec61/SecY channel. Annu Rev Cell Dev Biol 2005 3.09
15 Gangliosides are receptors for murine polyoma virus and SV40. EMBO J 2003 2.99
16 Rough sheets and smooth tubules. Cell 2006 2.97
17 Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane. Proc Natl Acad Sci U S A 2005 2.81
18 Mechanisms shaping the membranes of cellular organelles. Annu Rev Cell Dev Biol 2009 2.71
19 Mechanisms of Sec61/SecY-mediated protein translocation across membranes. Annu Rev Biophys 2011 2.40
20 Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p. Cell 2010 2.33
21 The plug domain of the SecY protein stabilizes the closed state of the translocation channel and maintains a membrane seal. Mol Cell 2007 2.18
22 Protein translocation is mediated by oligomers of the SecY complex with one SecY copy forming the channel. Cell 2007 2.17
23 Three-dimensional structure of the bacterial protein-translocation complex SecYEG. Nature 2002 2.16
24 The signal sequence coding region promotes nuclear export of mRNA. PLoS Biol 2007 2.09
25 Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes. Proc Natl Acad Sci U S A 2011 2.06
26 The ATPase SpoIIIE transports DNA across fused septal membranes during sporulation in Bacillus subtilis. Cell 2007 2.03
27 Stacked endoplasmic reticulum sheets are connected by helicoidal membrane motifs. Cell 2013 1.97
28 Architecture of the ribosome-channel complex derived from native membranes. J Mol Biol 2005 1.97
29 Targeting of rough endoplasmic reticulum membrane proteins and ribosomes in invertebrate neurons. Mol Biol Cell 2002 1.97
30 Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY. J Cell Biol 2005 1.93
31 Unfolded cholera toxin is transferred to the ER membrane and released from protein disulfide isomerase upon oxidation by Ero1. J Cell Biol 2002 1.86
32 A large conformational change of the translocation ATPase SecA. Proc Natl Acad Sci U S A 2004 1.86
33 A role for the two-helix finger of the SecA ATPase in protein translocation. Nature 2008 1.75
34 Crystal structure of the long-chain fatty acid transporter FadL. Science 2004 1.74
35 Role of ubiquitination in retro-translocation of cholera toxin and escape of cytosolic degradation. EMBO Rep 2002 1.71
36 Single copies of Sec61 and TRAP associate with a nontranslating mammalian ribosome. Structure 2008 1.68
37 Ribosome binding of a single copy of the SecY complex: implications for protein translocation. Mol Cell 2007 1.59
38 Polyubiquitin serves as a recognition signal, rather than a ratcheting molecule, during retrotranslocation of proteins across the endoplasmic reticulum membrane. J Biol Chem 2003 1.55
39 Weaving the web of ER tubules. Cell 2011 1.53
40 Processing and turnover of the Hedgehog protein in the endoplasmic reticulum. J Cell Biol 2011 1.48
41 Lipid interaction of the C terminus and association of the transmembrane segments facilitate atlastin-mediated homotypic endoplasmic reticulum fusion. Proc Natl Acad Sci U S A 2012 1.46
42 Structure of a bacterial homologue of vitamin K epoxide reductase. Nature 2010 1.44
43 Structure of the mammalian ribosome-channel complex at 17A resolution. J Mol Biol 2002 1.43
44 The dynamin-like GTPase Sey1p mediates homotypic ER fusion in S. cerevisiae. J Cell Biol 2012 1.38
45 Vitamin K epoxide reductase prefers ER membrane-anchored thioredoxin-like redox partners. Proc Natl Acad Sci U S A 2010 1.34
46 Role of p97 AAA-ATPase in the retrotranslocation of the cholera toxin A1 chain, a non-ubiquitinated substrate. J Biol Chem 2005 1.33
47 RecA-like motor ATPases--lessons from structures. Biochim Biophys Acta 2004 1.33
48 A novel dimer interface and conformational changes revealed by an X-ray structure of B. subtilis SecA. J Mol Biol 2006 1.27
49 Cooperation of transmembrane segments during the integration of a double-spanning protein into the ER membrane. EMBO J 2003 1.27
50 Preserving the membrane barrier for small molecules during bacterial protein translocation. Nature 2011 1.23
51 Gem1 and ERMES do not directly affect phosphatidylserine transport from ER to mitochondria or mitochondrial inheritance. Traffic 2012 1.21
52 Determining the conductance of the SecY protein translocation channel for small molecules. Mol Cell 2007 1.19
53 Mapping polypeptide interactions of the SecA ATPase during translocation. Proc Natl Acad Sci U S A 2009 1.18
54 Generation of nonidentical compartments in vesicular transport systems. J Cell Biol 2005 1.17
55 Interactions between Sec complex and prepro-alpha-factor during posttranslational protein transport into the endoplasmic reticulum. Mol Biol Cell 2003 1.12
56 Conformational flexibility and peptide interaction of the translocation ATPase SecA. J Mol Biol 2009 1.11
57 Bacterial protein translocation requires only one copy of the SecY complex in vivo. J Cell Biol 2012 1.08
58 Ribosome binding to and dissociation from translocation sites of the endoplasmic reticulum membrane. Mol Biol Cell 2006 1.04
59 E2-25K mediates US11-triggered retro-translocation of MHC class I heavy chains in a permeabilized cell system. Proc Natl Acad Sci U S A 2006 1.04
60 Structural insight into the protein translocation channel. Curr Opin Struct Biol 2004 0.99
61 Analysis of polypeptide movement in the SecY channel during SecA-mediated protein translocation. J Biol Chem 2008 0.98
62 Multiple mechanisms determine ER network morphology during the cell cycle in Xenopus egg extracts. J Cell Biol 2013 0.95
63 A conserved role for atlastin GTPases in regulating lipid droplet size. Cell Rep 2013 0.91
64 A novel centrosome-associated protein with affinity for microtubules. J Cell Sci 2002 0.87
65 The ER-associated degradation component Der1p and its homolog Dfm1p are contained in complexes with distinct cofactors of the ATPase Cdc48p. FEBS Lett 2008 0.87
66 Crystal structure of an unusual thioredoxin protein with a zinc finger domain. J Biol Chem 2007 0.85