Published in J Cell Biol on July 07, 2003
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin. J Cell Biol (2010) 5.94
Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system. Nat Cell Biol (2012) 3.90
UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover. Cell (2008) 3.41
Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways. Proc Natl Acad Sci U S A (2011) 3.20
The recognition and retrotranslocation of misfolded proteins from the endoplasmic reticulum. Traffic (2008) 3.07
Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane. Proc Natl Acad Sci U S A (2005) 3.01
Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane. Proc Natl Acad Sci U S A (2005) 2.81
Ubiquitin interactions of NZF zinc fingers. EMBO J (2004) 2.72
Exploring the specificity of the PI3K family inhibitor LY294002. Biochem J (2007) 2.66
RNA interference analysis of Legionella in Drosophila cells: exploitation of early secretory apparatus dynamics. PLoS Pathog (2006) 2.44
Dissecting the ER-associated degradation of a misfolded polytopic membrane protein. Cell (2008) 2.41
The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks. Nat Struct Mol Biol (2011) 2.23
The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks. Nat Cell Biol (2011) 2.15
SEL1L, the homologue of yeast Hrd3p, is involved in protein dislocation from the mammalian ER. J Cell Biol (2006) 2.13
Distinct roles for the AAA ATPases NSF and p97 in the secretory pathway. Mol Biol Cell (2003) 2.09
Int6 and Moe1 interact with Cdc48 to regulate ERAD and proper chromosome segregation. Cell Cycle (2010) 2.08
Inhibition of p97-dependent protein degradation by Eeyarestatin I. J Biol Chem (2008) 2.07
Valosin-containing protein (p97) is a regulator of endoplasmic reticulum stress and of the degradation of N-end rule and ubiquitin-fusion degradation pathway substrates in mammalian cells. Mol Biol Cell (2006) 2.07
Regulation of retrotranslocation by p97-associated deubiquitinating enzyme ataxin-3. J Cell Biol (2006) 2.00
Cdc48/p97 mediates UV-dependent turnover of RNA Pol II. Mol Cell (2011) 1.91
The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment. EMBO J (2006) 1.83
The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER. Mol Cell (2009) 1.82
Linking axonal degeneration to microtubule remodeling by Spastin-mediated microtubule severing. J Cell Biol (2005) 1.80
Polyubiquitin chains: functions, structures, and mechanisms. Cell Mol Life Sci (2008) 1.75
Quality control: ER-associated degradation: protein quality control and beyond. J Cell Biol (2014) 1.75
A foldable CFTR{Delta}F508 biogenic intermediate accumulates upon inhibition of the Hsc70-CHIP E3 ubiquitin ligase. J Cell Biol (2004) 1.70
Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations. Nat Cell Biol (2011) 1.69
Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps. PLoS Pathog (2010) 1.66
Bap31 is an itinerant protein that moves between the peripheral endoplasmic reticulum (ER) and a juxtanuclear compartment related to ER-associated Degradation. Mol Biol Cell (2008) 1.66
The nuclear envelope. Cold Spring Harb Perspect Biol (2010) 1.64
Regulating mitochondrial outer membrane proteins by ubiquitination and proteasomal degradation. Curr Opin Cell Biol (2011) 1.62
Inhibitors of the AAA+ chaperone p97. Molecules (2015) 1.61
The Magnaporthe oryzae effector AvrPiz-t targets the RING E3 ubiquitin ligase APIP6 to suppress pathogen-associated molecular pattern-triggered immunity in rice. Plant Cell (2012) 1.55
VCIP135 acts as a deubiquitinating enzyme during p97-p47-mediated reassembly of mitotic Golgi fragments. J Cell Biol (2004) 1.55
Two distinct surveillance mechanisms monitor meiotic chromosome metabolism in budding yeast. Curr Biol (2006) 1.52
Ubiquitin signals proteolysis-independent stripping of transcription factors. Mol Cell (2014) 1.49
Conformational changes in the AAA ATPase p97-p47 adaptor complex. EMBO J (2006) 1.48
Requirements for the selective degradation of CD4 receptor molecules by the human immunodeficiency virus type 1 Vpu protein in the endoplasmic reticulum. Retrovirology (2007) 1.48
Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformation. Mol Cell Biol (2009) 1.47
An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis. EMBO J (2006) 1.45
BAP31 and BiP are essential for dislocation of SV40 from the endoplasmic reticulum to the cytosol. Nat Cell Biol (2011) 1.45
Cdc48/p97 promotes degradation of aberrant nascent polypeptides bound to the ribosome. Elife (2013) 1.44
Conserved ERAD-like quality control of a plant polytopic membrane protein. Plant Cell (2004) 1.39
Doa1 is a Cdc48 adapter that possesses a novel ubiquitin binding domain. Mol Cell Biol (2006) 1.39
Uncoupling retro-translocation and degradation in the ER-associated degradation of a soluble protein. EMBO J (2004) 1.38
ANCCA, an estrogen-regulated AAA+ ATPase coactivator for ERalpha, is required for coregulator occupancy and chromatin modification. Proc Natl Acad Sci U S A (2007) 1.37
Cdc48p(Npl4p/Ufd1p) binds and segregates membrane-anchored/tethered complexes via a polyubiquitin signal present on the anchors. Mol Cell (2007) 1.37
Cholera toxin: an intracellular journey into the cytosol by way of the endoplasmic reticulum. Toxins (Basel) (2010) 1.34
Enzymatic blockade of the ubiquitin-proteasome pathway. PLoS Biol (2011) 1.33
The role of the N-domain in the ATPase activity of the mammalian AAA ATPase p97/VCP. J Biol Chem (2012) 1.32
In vitro analysis of Hrd1p-mediated retrotranslocation of its multispanning membrane substrate 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase. J Biol Chem (2009) 1.31
The protein translocation channel binds proteasomes to the endoplasmic reticulum membrane. EMBO J (2005) 1.31
Regulation of nicotinic receptor expression by the ubiquitin-proteasome system. EMBO J (2004) 1.28
Modulation of HIV-1-host interaction: role of the Vpu accessory protein. Retrovirology (2010) 1.26
An endoplasmic reticulum (ER) membrane complex composed of SPFH1 and SPFH2 mediates the ER-associated degradation of inositol 1,4,5-trisphosphate receptors. J Biol Chem (2009) 1.26
Structure-activity relationship study reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPase. ChemMedChem (2013) 1.25
The life cycle of the metazoan nuclear envelope. Curr Opin Cell Biol (2008) 1.24
Structure and function of the yeast U-box-containing ubiquitin ligase Ufd2p. Proc Natl Acad Sci U S A (2007) 1.24
Structural insights into the p97-Ufd1-Npl4 complex. Proc Natl Acad Sci U S A (2007) 1.22
Ubiquitylation of an ERAD substrate occurs on multiple types of amino acids. Mol Cell (2010) 1.21
Lysine methylation of VCP by a member of a novel human protein methyltransferase family. Nat Commun (2012) 1.21
The ERAD inhibitor Eeyarestatin I is a bifunctional compound with a membrane-binding domain and a p97/VCP inhibitory group. PLoS One (2010) 1.21
Deciphering the ubiquitin-mediated pathway in apicomplexan parasites: a potential strategy to interfere with parasite virulence. PLoS One (2008) 1.18
The complexities of p97 function in health and disease. Mol Biosyst (2010) 1.17
The p97/VCP ATPase is critical in muscle atrophy and the accelerated degradation of muscle proteins. EMBO J (2012) 1.15
Involvement of the p97-Ufd1-Npl4 complex in the regulated endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors. J Biol Chem (2005) 1.13
Role of the ubiquitin system in regulating ion transport. Pflugers Arch (2010) 1.12
Glycoprotein-specific ubiquitin ligases recognize N-glycans in unfolded substrates. EMBO Rep (2005) 1.12
Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domains. J Mol Biol (2014) 1.11
UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1α accumulation. BMC Biol (2012) 1.10
The p97 ATPase associates with EEA1 to regulate the size of early endosomes. Cell Res (2011) 1.09
The power of AAA-ATPases on the road of pre-60S ribosome maturation--molecular machines that strip pre-ribosomal particles. Biochim Biophys Acta (2011) 1.09
SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation. Cell Rep (2012) 1.09
A newly identified essential complex, Dre2-Tah18, controls mitochondria integrity and cell death after oxidative stress in yeast. PLoS One (2009) 1.08
Proteostasis regulation at the endoplasmic reticulum: a new perturbation site for targeted cancer therapy. Cell Res (2011) 1.07
Folding-competent and folding-defective forms of ricin A chain have different fates after retrotranslocation from the endoplasmic reticulum. Mol Biol Cell (2010) 1.07
A viral deubiquitylating enzyme restores dislocation of substrates from the endoplasmic reticulum (ER) in semi-intact cells. J Biol Chem (2012) 1.06
An Armadillo motif in Ufd3 interacts with Cdc48 and is involved in ubiquitin homeostasis and protein degradation. Proc Natl Acad Sci U S A (2009) 1.06
Mannose receptor polyubiquitination regulates endosomal recruitment of p97 and cytosolic antigen translocation for cross-presentation. Proc Natl Acad Sci U S A (2011) 1.05
ER Stress Proteins in Autoimmune and Inflammatory Diseases. Front Immunol (2012) 1.04
E2-25K mediates US11-triggered retro-translocation of MHC class I heavy chains in a permeabilized cell system. Proc Natl Acad Sci U S A (2006) 1.04
Roles of p97-associated deubiquitinases in protein quality control at the endoplasmic reticulum. Curr Protein Pept Sci (2012) 1.03
The RAD23 family provides an essential connection between the 26S proteasome and ubiquitylated proteins in Arabidopsis. Plant Cell (2010) 1.03
Hsp90-mediated cytosolic refolding of exogenous proteins internalized by dendritic cells. EMBO J (2007) 1.02
Huntingtin interacts with the cue domain of gp78 and inhibits gp78 binding to ubiquitin and p97/VCP. PLoS One (2010) 1.02
Derlin-1 is overexpressed in human breast carcinoma and protects cancer cells from endoplasmic reticulum stress-induced apoptosis. Breast Cancer Res (2008) 1.02
Transmembrane domain determinants of CD4 Downregulation by HIV-1 Vpu. J Virol (2011) 1.01
Stalled proteasomes are directly relieved by P97 recruitment. J Biol Chem (2011) 1.01
The transmembrane segment of a tail-anchored protein determines its degradative fate through dislocation from the endoplasmic reticulum. J Biol Chem (2010) 1.01
Decreased ER-associated degradation of alpha-TCR induced by Grp78 depletion with the SubAB cytotoxin. Int J Biochem Cell Biol (2008) 1.00
Evading the proteasome: absence of lysine residues contributes to pertussis toxin activity by evasion of proteasome degradation. Infect Immun (2007) 1.00
Altered intersubunit communication is the molecular basis for functional defects of pathogenic p97 mutants. J Biol Chem (2013) 0.99
Mutant Atp13a2 proteins involved in parkinsonism are degraded by ER-associated degradation and sensitize cells to ER-stress induced cell death. Hum Mol Genet (2011) 0.99
Interprotomer motion-transmission mechanism for the hexameric AAA ATPase p97. Proc Natl Acad Sci U S A (2012) 0.99
BAT3 guides misfolded glycoproteins out of the endoplasmic reticulum. PLoS One (2011) 0.98
Quantitative cell-based protein degradation assays to identify and classify drugs that target the ubiquitin-proteasome system. J Biol Chem (2011) 0.98
Identification of Caspase-6-mediated processing of the valosin containing protein (p97) in Alzheimer's disease: a novel link to dysfunction in ubiquitin proteasome system-mediated protein degradation. J Neurosci (2010) 0.97
Distinct conformations of the protein complex p97-Ufd1-Npl4 revealed by electron cryomicroscopy. Proc Natl Acad Sci U S A (2012) 0.97
Dislocation of HMG-CoA reductase and Insig-1, two polytopic endoplasmic reticulum proteins, en route to proteasomal degradation. Mol Biol Cell (2009) 0.96
Signal-induced disassembly of the SCF ubiquitin ligase complex by Cdc48/p97. Mol Cell (2012) 0.96
The Hsp70 and Hsp60 chaperone machines. Cell (1998) 13.79
The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol. Cell (1996) 8.25
The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol. Nature (2001) 7.59
Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair. Cell (1999) 6.56
AAA+ superfamily ATPases: common structure--diverse function. Genes Cells (2001) 5.83
A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways. EMBO J (2000) 4.48
Retro-translocation of proteins from the endoplasmic reticulum into the cytosol. Nat Rev Mol Cell Biol (2002) 4.29
Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48. Nat Cell Biol (2002) 4.06
p47 is a cofactor for p97-mediated membrane fusion. Nature (1997) 4.02
AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation. Mol Cell Biol (2002) 3.77
Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly. Nat Cell Biol (2001) 3.67
Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone. Cell (2001) 3.62
The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum. Proc Natl Acad Sci U S A (2001) 3.39
Structure of the AAA ATPase p97. Mol Cell (2000) 3.37
Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation. Nat Cell Biol (2001) 3.15
Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1-Npl4. EMBO J (2002) 3.12
Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates. EMBO J (2002) 2.74
HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins. Mol Biol Cell (2001) 2.65
Endoproteolytic activity of the proteasome. Science (2002) 2.56
ER protein quality control and proteasome-mediated protein degradation. Semin Cell Dev Biol (1999) 2.55
Syntaxin 5 is a common component of the NSF- and p97-mediated reassembly pathways of Golgi cisternae from mitotic Golgi fragments in vitro. Cell (1998) 2.54
Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle. Nat Struct Biol (2002) 2.38
VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo. J Cell Biol (2002) 2.06
ER quality control: towards an understanding at the molecular level. Curr Opin Cell Biol (2001) 2.04
Defining a pathway of communication from the C-terminal peptide binding domain to the N-terminal ATPase domain in a AAA protein. Mol Cell (2002) 1.82
Endoplasmic reticulum (ER)-associated degradation of T cell receptor subunits. Involvement of ER-associated ubiquitin-conjugating enzymes (E2s). J Biol Chem (2001) 1.74
The pathway of US11-dependent degradation of MHC class I heavy chains involves a ubiquitin-conjugated intermediate. J Cell Biol (1999) 1.74
Structure and ubiquitin interactions of the conserved zinc finger domain of Npl4. J Biol Chem (2003) 1.72
Protein binding and unfolding by the chaperone ClpA and degradation by the protease ClpAP. Proc Natl Acad Sci U S A (2000) 1.72
Polyubiquitination is required for US11-dependent movement of MHC class I heavy chain from endoplasmic reticulum into cytosol. Mol Biol Cell (2001) 1.69
The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation. Mol Biol Cell (2001) 1.66
ATPase activity of p97-valosin-containing protein (VCP). D2 mediates the major enzyme activity, and D1 contributes to the heat-induced activity. J Biol Chem (2002) 1.66
A major conformational change in p97 AAA ATPase upon ATP binding. Mol Cell (2000) 1.61
The Janus face of the archaeal Cdc48/p97 homologue VAT: protein folding versus unfolding. Biol Chem (1999) 1.49
The p47 co-factor regulates the ATPase activity of the membrane fusion protein, p97. FEBS Lett (1998) 1.46
The solution structure of VAT-N reveals a 'missing link' in the evolution of complex enzymes from a simple betaalphabetabeta element. Curr Biol (1999) 1.28
Cdc48 can distinguish between native and non-native proteins in the absence of cofactors. FEBS Lett (2002) 1.07
Selective stimulation of the D1 ATPase domain of N-ethylmaleimide-sensitive fusion protein (NSF) by soluble NSF attachment proteins. FEBS Lett (1998) 1.02
X-ray structure of a protein-conducting channel. Nature (2003) 9.20
A class of membrane proteins shaping the tubular endoplasmic reticulum. Cell (2006) 8.53
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Nature (2004) 6.37
Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins. Cell (2006) 5.54
Retro-translocation of proteins from the endoplasmic reticulum into the cytosol. Nat Rev Mol Cell Biol (2002) 4.29
Mathematical models of protein kinase signal transduction. Mol Cell (2002) 4.08
A class of dynamin-like GTPases involved in the generation of the tubular ER network. Cell (2009) 3.88
Structure of a complex of the ATPase SecA and the protein-translocation channel. Nature (2008) 3.73
Membrane proteins of the endoplasmic reticulum induce high-curvature tubules. Science (2008) 3.60
Mechanisms determining the morphology of the peripheral ER. Cell (2010) 3.35
Structural organization of the endoplasmic reticulum. EMBO Rep (2002) 3.25
The reticulon and DP1/Yop1p proteins form immobile oligomers in the tubular endoplasmic reticulum. J Biol Chem (2008) 3.13
Protein translocation by the Sec61/SecY channel. Annu Rev Cell Dev Biol (2005) 3.09
Gangliosides are receptors for murine polyoma virus and SV40. EMBO J (2003) 2.99
Rough sheets and smooth tubules. Cell (2006) 2.97
Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin. Nature (2007) 2.84
Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane. Proc Natl Acad Sci U S A (2005) 2.81
Ubiquitin interactions of NZF zinc fingers. EMBO J (2004) 2.72
Mechanisms shaping the membranes of cellular organelles. Annu Rev Cell Dev Biol (2009) 2.71
Mechanisms of Sec61/SecY-mediated protein translocation across membranes. Annu Rev Biophys (2011) 2.40
Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p. Cell (2010) 2.33
The plug domain of the SecY protein stabilizes the closed state of the translocation channel and maintains a membrane seal. Mol Cell (2007) 2.18
Protein translocation is mediated by oligomers of the SecY complex with one SecY copy forming the channel. Cell (2007) 2.17
Three-dimensional structure of the bacterial protein-translocation complex SecYEG. Nature (2002) 2.16
The signal sequence coding region promotes nuclear export of mRNA. PLoS Biol (2007) 2.09
Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes. Proc Natl Acad Sci U S A (2011) 2.06
The ATPase SpoIIIE transports DNA across fused septal membranes during sporulation in Bacillus subtilis. Cell (2007) 2.03
Stacked endoplasmic reticulum sheets are connected by helicoidal membrane motifs. Cell (2013) 1.97
Targeting of rough endoplasmic reticulum membrane proteins and ribosomes in invertebrate neurons. Mol Biol Cell (2002) 1.97
Architecture of the ribosome-channel complex derived from native membranes. J Mol Biol (2005) 1.97
Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY. J Cell Biol (2005) 1.93
Unfolded cholera toxin is transferred to the ER membrane and released from protein disulfide isomerase upon oxidation by Ero1. J Cell Biol (2002) 1.86
A large conformational change of the translocation ATPase SecA. Proc Natl Acad Sci U S A (2004) 1.86
The AAA-ATPase Cdc48/p97 regulates spindle disassembly at the end of mitosis. Cell (2003) 1.84
Caveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation. J Cell Biol (2010) 1.83
A role for the two-helix finger of the SecA ATPase in protein translocation. Nature (2008) 1.75
Crystal structure of the long-chain fatty acid transporter FadL. Science (2004) 1.74
Structure and ubiquitin interactions of the conserved zinc finger domain of Npl4. J Biol Chem (2003) 1.72
Role of ubiquitination in retro-translocation of cholera toxin and escape of cytosolic degradation. EMBO Rep (2002) 1.71
Single copies of Sec61 and TRAP associate with a nontranslating mammalian ribosome. Structure (2008) 1.68
Ribosome binding of a single copy of the SecY complex: implications for protein translocation. Mol Cell (2007) 1.59
Polyubiquitin serves as a recognition signal, rather than a ratcheting molecule, during retrotranslocation of proteins across the endoplasmic reticulum membrane. J Biol Chem (2003) 1.55
VCIP135 acts as a deubiquitinating enzyme during p97-p47-mediated reassembly of mitotic Golgi fragments. J Cell Biol (2004) 1.55
Weaving the web of ER tubules. Cell (2011) 1.53
Processing and turnover of the Hedgehog protein in the endoplasmic reticulum. J Cell Biol (2011) 1.48
Lipid interaction of the C terminus and association of the transmembrane segments facilitate atlastin-mediated homotypic endoplasmic reticulum fusion. Proc Natl Acad Sci U S A (2012) 1.46
Structure of a bacterial homologue of vitamin K epoxide reductase. Nature (2010) 1.44
Structure of the mammalian ribosome-channel complex at 17A resolution. J Mol Biol (2002) 1.43
The AAA ATPase p97/VCP interacts with its alternative co-factors, Ufd1-Npl4 and p47, through a common bipartite binding mechanism. J Biol Chem (2004) 1.41
The dynamin-like GTPase Sey1p mediates homotypic ER fusion in S. cerevisiae. J Cell Biol (2012) 1.38
Vitamin K epoxide reductase prefers ER membrane-anchored thioredoxin-like redox partners. Proc Natl Acad Sci U S A (2010) 1.34
Role of p97 AAA-ATPase in the retrotranslocation of the cholera toxin A1 chain, a non-ubiquitinated substrate. J Biol Chem (2005) 1.33
RecA-like motor ATPases--lessons from structures. Biochim Biophys Acta (2004) 1.33
A novel dimer interface and conformational changes revealed by an X-ray structure of B. subtilis SecA. J Mol Biol (2006) 1.27
Cooperation of transmembrane segments during the integration of a double-spanning protein into the ER membrane. EMBO J (2003) 1.27
Preserving the membrane barrier for small molecules during bacterial protein translocation. Nature (2011) 1.23
Structural insights into the p97-Ufd1-Npl4 complex. Proc Natl Acad Sci U S A (2007) 1.22
Gem1 and ERMES do not directly affect phosphatidylserine transport from ER to mitochondria or mitochondrial inheritance. Traffic (2012) 1.21
Determining the conductance of the SecY protein translocation channel for small molecules. Mol Cell (2007) 1.19
Mapping polypeptide interactions of the SecA ATPase during translocation. Proc Natl Acad Sci U S A (2009) 1.18
Generation of nonidentical compartments in vesicular transport systems. J Cell Biol (2005) 1.17
Interactions between Sec complex and prepro-alpha-factor during posttranslational protein transport into the endoplasmic reticulum. Mol Biol Cell (2003) 1.12
Conformational flexibility and peptide interaction of the translocation ATPase SecA. J Mol Biol (2009) 1.11
Bacterial protein translocation requires only one copy of the SecY complex in vivo. J Cell Biol (2012) 1.08
Ribosome binding to and dissociation from translocation sites of the endoplasmic reticulum membrane. Mol Biol Cell (2006) 1.04
E2-25K mediates US11-triggered retro-translocation of MHC class I heavy chains in a permeabilized cell system. Proc Natl Acad Sci U S A (2006) 1.04
NSF- and SNARE-mediated membrane fusion is required for nuclear envelope formation and completion of nuclear pore complex assembly in Xenopus laevis egg extracts. J Cell Sci (2007) 1.00
Structural insight into the protein translocation channel. Curr Opin Struct Biol (2004) 0.99
Detailed structural insights into the p97-Npl4-Ufd1 interface. J Biol Chem (2007) 0.99
Analysis of polypeptide movement in the SecY channel during SecA-mediated protein translocation. J Biol Chem (2008) 0.98
Distinct conformations of the protein complex p97-Ufd1-Npl4 revealed by electron cryomicroscopy. Proc Natl Acad Sci U S A (2012) 0.97
Multiple mechanisms determine ER network morphology during the cell cycle in Xenopus egg extracts. J Cell Biol (2013) 0.95
A conserved role for atlastin GTPases in regulating lipid droplet size. Cell Rep (2013) 0.91
A novel centrosome-associated protein with affinity for microtubules. J Cell Sci (2002) 0.87
The ER-associated degradation component Der1p and its homolog Dfm1p are contained in complexes with distinct cofactors of the ATPase Cdc48p. FEBS Lett (2008) 0.87
Crystal structure of an unusual thioredoxin protein with a zinc finger domain. J Biol Chem (2007) 0.85