PubRank

Tom Misteli

Author PubWeight™ 239.98‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 2002 19.77
2 RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E). Nature 2011 10.77
3 Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells. Dev Cell 2006 8.53
4 Regulation of alternative splicing by histone modifications. Science 2010 7.98
5 Lamin A-dependent nuclear defects in human aging. Science 2006 6.71
6 Global transcription in pluripotent embryonic stem cells. Cell Stem Cell 2008 5.81
7 Ubiquitination regulates PTEN nuclear import and tumor suppression. Cell 2007 5.62
8 The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis. Proc Natl Acad Sci U S A 2003 5.59
9 Chromatin in pluripotent embryonic stem cells and differentiation. Nat Rev Mol Cell Biol 2006 5.18
10 Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome. Nat Med 2005 5.01
11 Epigenetics in alternative pre-mRNA splicing. Cell 2011 4.74
12 Maintenance of stable heterochromatin domains by dynamic HP1 binding. Science 2003 4.74
13 A kinetic framework for a mammalian RNA polymerase in vivo. Science 2002 4.42
14 Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins. Mol Cell Biol 2004 4.41
15 Positional stability of single double-strand breaks in mammalian cells. Nat Cell Biol 2007 4.35
16 Transcription dynamics. Mol Cell 2009 4.15
17 Spatial proximity of translocation-prone gene loci in human lymphomas. Nat Genet 2003 3.91
18 Activation of the cellular DNA damage response in the absence of DNA lesions. Science 2008 3.17
19 Measurement of dynamic protein binding to chromatin in vivo, using photobleaching microscopy. Methods Enzymol 2004 3.02
20 Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing. Nat Cell Biol 2008 2.93
21 TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression. Proc Natl Acad Sci U S A 2008 2.58
22 Tissue-specific spatial organization of genomes. Genome Biol 2004 2.57
23 Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A 2006 2.53
24 Cell biology: chromosome territories. Nature 2007 2.47
25 Ageing-related chromatin defects through loss of the NURD complex. Nat Cell Biol 2009 2.40
26 Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus. J Cell Sci 2006 2.37
27 Network of dynamic interactions between histone H1 and high-mobility-group proteins in chromatin. Mol Cell Biol 2004 2.33
28 Chromosome positioning in the interphase nucleus. Trends Cell Biol 2002 2.32
29 The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks. Nature 2007 2.30
30 The meaning of gene positioning. Cell 2008 2.16
31 Functional implications of genome topology. Nat Struct Mol Biol 2013 2.13
32 Spatial genome organization in the formation of chromosomal translocations. Semin Cancer Biol 2006 2.12
33 HTLV-1-encoded p30II is a post-transcriptional negative regulator of viral replication. Nat Med 2004 1.97
34 Spatial dynamics of chromosome translocations in living cells. Science 2013 1.95
35 Mapping the interaction surface of linker histone H1(0) with the nucleosome of native chromatin in vivo. Nat Struct Mol Biol 2006 1.94
36 In vivo kinetics of Cajal body components. J Cell Biol 2004 1.91
37 Condensed mitotic chromatin is accessible to transcription factors and chromatin structural proteins. J Cell Biol 2004 1.86
38 The lamin protein family. Genome Biol 2011 1.85
39 Functional association of Sun1 with nuclear pore complexes. J Cell Biol 2007 1.81
40 Human chromokinesin KIF4A functions in chromosome condensation and segregation. J Cell Biol 2004 1.81
41 Competition between histone H1 and HMGN proteins for chromatin binding sites. EMBO Rep 2002 1.74
42 Biogenesis of nuclear bodies. Cold Spring Harb Perspect Biol 2010 1.69
43 Allele-specific nuclear positioning of the monoallelically expressed astrocyte marker GFAP. Genes Dev 2008 1.62
44 In vitro generation of human cells with cancer stem cell properties. Nat Cell Biol 2011 1.61
45 Quantitation of GFP-fusion proteins in single living cells. J Struct Biol 2002 1.59
46 Conservation of relative chromosome positioning in normal and cancer cells. Curr Biol 2002 1.58
47 Locus-specific and activity-independent gene repositioning during early tumorigenesis. J Cell Biol 2008 1.56
48 The road much traveled: trafficking in the cell nucleus. Curr Opin Cell Biol 2006 1.52
49 A cyclophilin functions in pre-mRNA splicing. EMBO J 2002 1.49
50 Modulation of RNA polymerase assembly dynamics in transcriptional regulation. Mol Cell 2008 1.47
51 Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesis. J Biol Chem 2002 1.45
52 Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma. Proc Natl Acad Sci U S A 2009 1.44
53 Chromokinesins: multitalented players in mitosis. Trends Cell Biol 2005 1.41
54 Spatial genome organization. Exp Cell Res 2004 1.39
55 LINC complexes in health and disease. Nucleus 2011 1.37
56 Mobility and immobility of chromatin in transcription and genome stability. Curr Opin Genet Dev 2007 1.37
57 Lamin A/C-mediated neuromuscular junction defects in Emery-Dreifuss muscular dystrophy. J Cell Biol 2009 1.36
58 Aberrant nuclear trafficking of La protein leads to disordered processing of associated precursor tRNAs. Mol Cell 2002 1.30
59 In vivo dynamics of Swi6 in yeast: evidence for a stochastic model of heterochromatin. Mol Cell Biol 2004 1.26
60 Potential roles for ubiquitin and the proteasome during ribosome biogenesis. Mol Cell Biol 2006 1.25
61 An uncertainty principle in chromosome positioning. Trends Cell Biol 2003 1.19
62 Post-natal myogenic and adipogenic developmental: defects and metabolic impairment upon loss of A-type lamins. Nucleus 2011 1.19
63 More than a splicing code: integrating the role of RNA, chromatin and non-coding RNA in alternative splicing regulation. Curr Opin Genet Dev 2011 1.18
64 Eliminating the impact of the Impact Factor. J Cell Biol 2013 1.15
65 Identification of differential protein interactors of lamin A and progerin. Nucleus 2010 1.14
66 Disease-specific gene repositioning in breast cancer. J Cell Biol 2009 1.13
67 Nucleolomics: an inventory of the nucleolus. Mol Cell 2002 1.10
68 Recruitment of dioxin receptor to active transcription sites. Mol Biol Cell 2002 1.08
69 The central role of chromatin maintenance in aging. Aging (Albany NY) 2009 1.07
70 Evaluation of substituted 6-arylquinazolin-4-amines as potent and selective inhibitors of cdc2-like kinases (Clk). Bioorg Med Chem Lett 2009 1.06
71 Differential in vivo binding dynamics of somatic and oocyte-specific linker histones in oocytes and during ES cell nuclear transfer. Mol Biol Cell 2005 1.05
72 A non-random walk through the genome. Genome Biol 2005 1.04
73 Systems biology in the cell nucleus. J Cell Sci 2005 1.04
74 Mapping of lamin A- and progerin-interacting genome regions. Chromosoma 2012 1.01
75 New tools for JCB. J Cell Biol 2011 1.01
76 Measuring dynamics of nuclear proteins by photobleaching. Curr Protoc Cell Biol 2003 1.01
77 SnapShot: Chromosome confirmation capture. Cell 2012 1.00
78 Friends, colleagues, authors, lend us your data. J Cell Biol 2010 1.00
79 Genome instability in progeria: when repair gets old. Nat Med 2005 0.99
80 The JCB DataViewer scales up. J Cell Biol 2012 0.98
81 Tumor formation via loss of a molecular motor protein. Curr Biol 2006 0.97
82 Non-coding RNAs in DNA damage and repair. FEBS Lett 2013 0.97
83 Chinese hamster ORC subunits dynamically associate with chromatin throughout the cell-cycle. Exp Cell Res 2005 0.95
84 The cell nucleus and aging: tantalizing clues and hopeful promises. PLoS Biol 2005 0.95
85 Cell biology: Nuclear order out of chaos. Nature 2008 0.93
86 On the contribution of spatial genome organization to cancerous chromosome translocations. J Natl Cancer Inst Monogr 2008 0.92
87 Automatic segmentation and supervised learning-based selection of nuclei in cancer tissue images. Cytometry A 2012 0.91
88 Genomes, proteomes, and dynamic networks in the cell nucleus. Histochem Cell Biol 2002 0.91
89 Differential recruitment of pre-mRNA splicing factors to alternatively spliced transcripts in vivo. PLoS Biol 2005 0.90
90 A tumor-promoting mechanism mediated by retrotransposon-encoded reverse transcriptase is active in human transformed cell lines. Oncotarget 2013 0.89
91 Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk). Bioorg Med Chem Lett 2011 0.89
92 DNA damage, chromatin, and transcription: the trinity of aging. Curr Opin Cell Biol 2012 0.88
93 Splicing misplaced. Cell 2005 0.88
94 Automatic nuclei segmentation and spatial FISH analysis for cancer detection. Conf Proc IEEE Eng Med Biol Soc 2009 0.88
95 H1FOO is coupled to the initiation of oocytic growth. Biol Reprod 2004 0.88
96 Ranked retrieval of segmented nuclei for objective assessment of cancer gene repositioning. BMC Bioinformatics 2012 0.87
97 Systematic identification of pathological lamin A interactors. Mol Biol Cell 2014 0.86
98 Good news in the nuclear envelope: loss of lamin A might be a gain. J Clin Invest 2006 0.86
99 Formation of nuclear splicing factor compartments is independent of lamins A/C. Mol Biol Cell 2004 0.86
100 Chromatin maintenance by a molecular motor protein. Nucleus 2011 0.86
101 Mapping of protein- and chromatin-interactions at the nuclear lamina. Nucleus 2010 0.84
102 The dangers of transcription. Cell 2009 0.83
103 The cellular etiology of chromosome translocations. Curr Opin Cell Biol 2013 0.83
104 Computational cell biology. J Cell Biol 2003 0.82
105 Parallel genome universes. Nat Biotechnol 2012 0.81
106 Identification of mammalian protein quality control factors by high-throughput cellular imaging. PLoS One 2012 0.81
107 E2F-dependent repression of topoisomerase II regulates heterochromatin formation and apoptosis in cells with melanoma-prone mutation. Cancer Res 2005 0.81
108 Deep Imaging: the next frontier in microscopy. Histochem Cell Biol 2014 0.79
109 Descriptive no more: the dawn of high-throughput microscopy. Trends Cell Biol 2010 0.78
110 A nucleolar disappearing act in somatic cloning. Nat Cell Biol 2003 0.78
111 Nuclear architecture--an island no more. Dev Cell 2007 0.77
112 Division of labor: minor splicing in the cytoplasm. Cell 2007 0.77
113 Cell biology beyond the cell. J Cell Biol 2010 0.76
114 Cell biology: at the center of modern biomedicine. J Cell Biol 2012 0.75
115 Minimizing the "re" in review. J Cell Biol 2012 0.75
116 The changing world of modern cell biology. J Cell Biol 2009 0.75
117 New science - new ways to communicate it. J Cell Biol 2009 0.75
118 In vivo imaging. Methods 2003 0.75
119 25 years of Current Opinion in Cell Biology. Curr Opin Cell Biol 2013 0.75
120 Supervised learning framework for screening nuclei in tissue sections. Conf Proc IEEE Eng Med Biol Soc 2011 0.75
121 JCB meeting: Cell Biology of Disease. J Cell Biol 2009 0.75