Published in Nat Methods on April 01, 2012
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The BioGRID interaction database: 2013 update. Nucleic Acids Res (2012) 6.09
The MIntAct project--IntAct as a common curation platform for 11 molecular interaction databases. Nucleic Acids Res (2013) 4.39
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InnateDB: systems biology of innate immunity and beyond--recent updates and continuing curation. Nucleic Acids Res (2012) 2.66
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The European Bioinformatics Institute's data resources 2014. Nucleic Acids Res (2013) 1.17
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VirusMentha: a new resource for virus-host protein interactions. Nucleic Acids Res (2014) 0.99
Proteomics-based methods for discovery, quantification, and validation of protein-protein interactions. Anal Chem (2012) 0.98
Using biological networks to integrate, visualize and analyze genomics data. Genet Sel Evol (2016) 0.96
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Fundamentals of protein interaction network mapping. Mol Syst Biol (2015) 0.93
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Protein-protein interactions and genetic diseases: The interactome. Biochim Biophys Acta (2014) 0.90
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Comprehensive Map of Molecules Implicated in Obesity. PLoS One (2016) 0.88
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. Nat Commun (2016) 0.87
The BioGRID interaction database: 2017 update. Nucleic Acids Res (2016) 0.86
Computational analysis of the LRRK2 interactome. PeerJ (2015) 0.86
canSAR: an updated cancer research and drug discovery knowledgebase. Nucleic Acids Res (2015) 0.86
SIGNOR: a database of causal relationships between biological entities. Nucleic Acids Res (2015) 0.86
MatrixDB, the extracellular matrix interaction database: updated content, a new navigator and expanded functionalities. Nucleic Acids Res (2014) 0.85
The human DEPhOsphorylation database DEPOD: a 2015 update. Nucleic Acids Res (2014) 0.85
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The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets. Mol Cell Proteomics (2014) 0.84
APP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active Zone. PLoS Comput Biol (2016) 0.83
A visual review of the interactome of LRRK2: Using deep-curated molecular interaction data to represent biology. Proteomics (2015) 0.82
HitPredict version 4: comprehensive reliability scoring of physical protein-protein interactions from more than 100 species. Database (Oxford) (2015) 0.82
APID interactomes: providing proteome-based interactomes with controlled quality for multiple species and derived networks. Nucleic Acids Res (2016) 0.81
Computational Prediction of Protein-Protein Interaction Networks: Algo-rithms and Resources. Curr Genomics (2013) 0.81
Virus-host interactomics: new insights and opportunities for antiviral drug discovery. Genome Med (2014) 0.81
Shared resources, shared costs--leveraging biocuration resources. Database (Oxford) (2015) 0.80
VHLdb: A database of von Hippel-Lindau protein interactors and mutations. Sci Rep (2016) 0.79
Visual data mining of biological networks: one size does not fit all. PLoS Comput Biol (2013) 0.79
Reconstruction of the experimentally supported human protein interactome: what can we learn? BMC Syst Biol (2013) 0.79
A framework for biomedical figure segmentation towards image-based document retrieval. BMC Syst Biol (2013) 0.79
Intrinsic Disorder in Transmembrane Proteins: Roles in Signaling and Topology Prediction. PLoS One (2016) 0.78
Integrated inference and evaluation of host-fungi interaction networks. Front Microbiol (2015) 0.78
Distinctive Behaviors of Druggable Proteins in Cellular Networks. PLoS Comput Biol (2015) 0.78
A molecular classification of human mesenchymal stromal cells. PeerJ (2016) 0.78
The human plasma membrane peripherome: visualization and analysis of interactions. Biomed Res Int (2014) 0.78
The hierarchical organization of natural protein interaction networks confers self-organization properties on pseudocells. BMC Syst Biol (2015) 0.78
Reconstruction and Application of Protein-Protein Interaction Network. Int J Mol Sci (2016) 0.77
Identification of the BRD1 interaction network and its impact on mental disorder risk. Genome Med (2016) 0.77
The Confidence Information Ontology: a step towards a standard for asserting confidence in annotations. Database (Oxford) (2015) 0.77
Exploring novel mechanistic insights in Alzheimer's disease by assessing reliability of protein interactions. Sci Rep (2015) 0.77
A survey of protein interaction data and multigenic inherited disorders. BMC Bioinformatics (2013) 0.77
A DEK domain-containing protein modulates chromatin structure and function in Arabidopsis. Plant Cell (2014) 0.77
Glycosaminoglycanomics: where we are. Glycoconj J (2016) 0.77
Minireview: progress and challenges in proteomics data management, sharing, and integration. Mol Endocrinol (2012) 0.76
The drug-minded protein interaction database (DrumPID) for efficient target analysis and drug development. Database (Oxford) (2016) 0.76
Data integration in biological research: an overview. J Biol Res (Thessalon) (2015) 0.75
CellWhere: graphical display of interaction networks organized on subcellular localizations. Nucleic Acids Res (2015) 0.75
Nestedness across biological scales. PLoS One (2017) 0.75
HPIDB 2.0: a curated database for host-pathogen interactions. Database (Oxford) (2016) 0.75
PROPER: global protein interaction network alignment through percolation matching. BMC Bioinformatics (2016) 0.75
Proteome-Scale Human Interactomics. Trends Biochem Sci (2017) 0.75
PIPINO: A Software Package to Facilitate the Identification of Protein-Protein Interactions from Affinity Purification Mass Spectrometry Data. Biomed Res Int (2016) 0.75
Epigenetic profiling of human brain differential DNA methylation networks in schizophrenia. BMC Med Genomics (2016) 0.75
An Atlas of the Human Kinome Reveals the Mutational Landscape Underlying Dysregulated Phosphorylation Cascades in Cancer. Cancer Res (2016) 0.75
Non-Coding RNAs in Lung Cancer: Contribution of Bioinformatics Analysis to the Development of Non-Invasive Diagnostic Tools. Genes (Basel) (2016) 0.75
SorghumFDB: sorghum functional genomics database with multidimensional network analysis. Database (Oxford) (2016) 0.75
In silico identification of essential proteins in Corynebacterium pseudotuberculosis based on protein-protein interaction networks. BMC Syst Biol (2016) 0.75
Equine skeletal muscle adaptations to exercise and training: evidence of differential regulation of autophagosomal and mitochondrial components. BMC Genomics (2017) 0.75
Exploring the cross talk between ER stress and inflammation in age-related macular degeneration. PLoS One (2017) 0.75
Yeast non-coding RNA interaction network. RNA (2017) 0.75
Towards a proteome-scale map of the human protein-protein interaction network. Nature (2005) 24.76
Human Protein Reference Database--2009 update. Nucleic Acids Res (2008) 21.25
A protein interaction map of Drosophila melanogaster. Science (2003) 20.06
A human protein-protein interaction network: a resource for annotating the proteome. Cell (2005) 18.97
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored. Nucleic Acids Res (2010) 18.73
The HUPO PSI's molecular interaction format--a community standard for the representation of protein interaction data. Nat Biotechnol (2004) 16.08
DIP, the Database of Interacting Proteins: a research tool for studying cellular networks of protein interactions. Nucleic Acids Res (2002) 15.70
The Biomolecular Interaction Network Database and related tools 2005 update. Nucleic Acids Res (2005) 12.94
Database resources of the National Center for Biotechnology Information. Nucleic Acids Res (2009) 12.51
The BioGRID Interaction Database: 2008 update. Nucleic Acids Res (2007) 11.83
Ongoing and future developments at the Universal Protein Resource. Nucleic Acids Res (2010) 11.32
The IntAct molecular interaction database in 2010. Nucleic Acids Res (2009) 9.85
The protein-protein interaction map of Helicobacter pylori. Nature (2001) 8.71
The minimum information required for reporting a molecular interaction experiment (MIMIx). Nat Biotechnol (2007) 8.24
Broadening the horizon--level 2.5 of the HUPO-PSI format for molecular interactions. BMC Biol (2007) 8.03
MPact: the MIPS protein interaction resource on yeast. Nucleic Acids Res (2006) 7.75
MINT, the molecular interaction database: 2009 update. Nucleic Acids Res (2009) 7.19
Pathguide: a pathway resource list. Nucleic Acids Res (2006) 6.05
PSICQUIC and PSISCORE: accessing and scoring molecular interactions. Nat Methods (2011) 5.01
InnateDB: facilitating systems-level analyses of the mammalian innate immune response. Mol Syst Biol (2008) 4.61
APID: Agile Protein Interaction DataAnalyzer. Nucleic Acids Res (2006) 2.91
iRefWeb: interactive analysis of consolidated protein interaction data and their supporting evidence. Database (Oxford) (2010) 2.47
Unequal evolutionary conservation of human protein interactions in interologous networks. Genome Biol (2007) 2.45
MPIDB: the microbial protein interaction database. Bioinformatics (2008) 2.42
The FEBS Letters/BioCreative II.5 experiment: making biological information accessible. Nat Biotechnol (2010) 2.18
MatrixDB, the extracellular matrix interaction database. Nucleic Acids Res (2010) 1.79
MINT and IntAct contribute to the Second BioCreative challenge: serving the text-mining community with high quality molecular interaction data. Genome Biol (2008) 1.76
The PSI semantic validator: a framework to check MIAPE compliance of proteomics data. Proteomics (2009) 1.62
Exhaustive benchmarking of the yeast two-hybrid system. Nat Methods (2010) 1.59
Recurated protein interaction datasets. Nat Methods (2009) 1.43
Literature curation of protein interactions: measuring agreement across major public databases. Database (Oxford) (2010) 1.33
The HUPO proteomics standards initiative--easing communication and minimizing data loss in a changing world. Brief Bioinform (2007) 1.04
A domain level interaction network of amyloid precursor protein and Abeta of Alzheimer's disease. Proteomics (2010) 0.96
Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature (2002) 37.66
The minimum information about a genome sequence (MIGS) specification. Nat Biotechnol (2008) 31.04
BioGRID: a general repository for interaction datasets. Nucleic Acids Res (2006) 22.41
MINT: a Molecular INTeraction database. FEBS Lett (2002) 17.21
The HUPO PSI's molecular interaction format--a community standard for the representation of protein interaction data. Nat Biotechnol (2004) 16.08
Reactome knowledgebase of human biological pathways and processes. Nucleic Acids Res (2008) 15.69
IntAct: an open source molecular interaction database. Nucleic Acids Res (2004) 15.02
The PRoteomics IDEntifications (PRIDE) database and associated tools: status in 2013. Nucleic Acids Res (2012) 13.14
Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project. Nat Biotechnol (2008) 12.96
MINT: the Molecular INTeraction database. Nucleic Acids Res (2006) 11.90
The BioGRID Interaction Database: 2008 update. Nucleic Acids Res (2007) 11.83
A common open representation of mass spectrometry data and its application to proteomics research. Nat Biotechnol (2004) 11.42
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Improving the Arabidopsis genome annotation using maximal transcript alignment assemblies. Nucleic Acids Res (2003) 11.03
The minimum information about a proteomics experiment (MIAPE). Nat Biotechnol (2007) 10.24
Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study. Nat Med (2008) 10.12
Genome sequence of Aedes aegypti, a major arbovirus vector. Science (2007) 9.19
The Ontology Lookup Service, a lightweight cross-platform tool for controlled vocabulary queries. BMC Bioinformatics (2006) 8.68
The Reactome pathway knowledgebase. Nucleic Acids Res (2013) 8.56
The chemical genomic portrait of yeast: uncovering a phenotype for all genes. Science (2008) 8.52
The BioGRID Interaction Database: 2011 update. Nucleic Acids Res (2010) 8.46
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The genome sequence of taurine cattle: a window to ruminant biology and evolution. Science (2009) 8.23
Protein interactions: two methods for assessment of the reliability of high throughput observations. Mol Cell Proteomics (2002) 8.11
Broadening the horizon--level 2.5 of the HUPO-PSI format for molecular interactions. BMC Biol (2007) 8.03
Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances. Nat Protoc (2008) 7.92
MPact: the MIPS protein interaction resource on yeast. Nucleic Acids Res (2006) 7.75
Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds. Science (2009) 7.64
PRIDE: the proteomics identifications database. Proteomics (2005) 7.52
The IntAct molecular interaction database in 2012. Nucleic Acids Res (2011) 7.49
Conserved patterns of protein interaction in multiple species. Proc Natl Acad Sci U S A (2005) 7.48
Global analysis of protein phosphorylation in yeast. Nature (2005) 7.46
Whole-genome sequencing and social-network analysis of a tuberculosis outbreak. N Engl J Med (2011) 7.35
MINT, the molecular interaction database: 2009 update. Nucleic Acids Res (2009) 7.19
Calling on a million minds for community annotation in WikiProteins. Genome Biol (2008) 7.11
A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules. Science (2001) 7.08
Systematic identification of pathways that couple cell growth and division in yeast. Science (2002) 6.95
ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins. Nucleic Acids Res (2003) 6.86
Online predicted human interaction database. Bioinformatics (2005) 6.83
PSORTb 3.0: improved protein subcellular localization prediction with refined localization subcategories and predictive capabilities for all prokaryotes. Bioinformatics (2010) 6.57
Integrating biological data--the Distributed Annotation System. BMC Bioinformatics (2008) 6.56
Metabolic reconstruction for metagenomic data and its application to the human microbiome. PLoS Comput Biol (2012) 6.27
Osprey: a network visualization system. Genome Biol (2003) 6.23
The BioGRID interaction database: 2013 update. Nucleic Acids Res (2012) 6.09
Peptide antimicrobial agents. Clin Microbiol Rev (2006) 6.04
A global protein kinase and phosphatase interaction network in yeast. Science (2010) 5.95
Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase. Cell (2003) 5.72
IslandViewer: an integrated interface for computational identification and visualization of genomic islands. Bioinformatics (2009) 5.69
A guide to the Proteomics Identifications Database proteomics data repository. Proteomics (2009) 5.63
MINT, the molecular interaction database: 2012 update. Nucleic Acids Res (2011) 5.25
Stem cell gene expression programs influence clinical outcome in human leukemia. Nat Med (2011) 5.24
Pseudomonas Genome Database: improved comparative analysis and population genomics capability for Pseudomonas genomes. Nucleic Acids Res (2010) 5.23
High-throughput mapping of a dynamic signaling network in mammalian cells. Science (2005) 5.21
The UniProt-GO Annotation database in 2011. Nucleic Acids Res (2011) 5.19
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PSICQUIC and PSISCORE: accessing and scoring molecular interactions. Nat Methods (2011) 5.01