Published in PLoS One on February 09, 2010
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Genetic analysis of the cytoplasmic dynein subunit families. PLoS Genet (2006) 2.35
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A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice. Proc Natl Acad Sci U S A (2009) 1.66
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Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease. Proc Natl Acad Sci U S A (2014) 1.53
DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome. Am J Hum Genet (2008) 1.45
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Homozygosity for the C9orf72 GGGGCC repeat expansion in frontotemporal dementia. Acta Neuropathol (2013) 1.41
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Identification of genetic loci affecting mouse-adapted bovine spongiform encephalopathy incubation time in mice. Neurogenetics (2002) 1.31
Adult onset global loss of the fto gene alters body composition and metabolism in the mouse. PLoS Genet (2013) 1.31
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Superoxide dismutase 1 and tgSOD1 mouse spinal cord seed fibrils, suggesting a propagative cell death mechanism in amyotrophic lateral sclerosis. PLoS One (2010) 1.25
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Development and function of the mammalian spleen. Bioessays (2007) 1.23
An ENU-induced mutation in mouse glycyl-tRNA synthetase (GARS) causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy. Dis Model Mech (2009) 1.22
Mechanistic basis of infertility of mouse intersubspecific hybrids. Proc Natl Acad Sci U S A (2013) 1.20
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Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome. Learn Mem (2008) 1.18
Regulatory variation at glypican-3 underlies a major growth QTL in mice. PLoS Biol (2005) 1.18
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Down's syndrome-like cardiac developmental defects in embryos of the transchromosomic Tc1 mouse. Cardiovasc Res (2010) 1.13
A mutation in the mitochondrial fission gene Dnm1l leads to cardiomyopathy. PLoS Genet (2010) 1.13
A mutation in the F-box gene, Fbxo11, causes otitis media in the Jeff mouse. Hum Mol Genet (2006) 1.13
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The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutation. Biochem J (2012) 1.11
IkappaB genetic polymorphisms and invasive pneumococcal disease. Am J Respir Crit Care Med (2007) 1.11
Differentially expressed protein markers in human submandibular and sublingual secretions. Int J Oncol (2004) 1.11
Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination. PLoS Biol (2009) 1.10
Is inhibition of kinase activity the only therapeutic strategy for LRRK2-associated Parkinson's disease? BMC Med (2012) 1.10
Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome. PLoS One (2013) 1.10
Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome. Hum Mol Genet (2009) 1.09
Cytoplasmic dynein heavy chain: the servant of many masters. Trends Neurosci (2013) 1.09
Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome. Blood (2010) 1.08
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Establishing normal plasma and 24-hour urinary biochemistry ranges in C3H, BALB/c and C57BL/6J mice following acclimatization in metabolic cages. Lab Anim (2010) 1.07
Lithium rescues synaptic plasticity and memory in Down syndrome mice. J Clin Invest (2012) 1.07
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The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear. BMC Dev Biol (2010) 1.06
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Sfrp1 and Sfrp2 are required for normal male sexual development in mice. Dev Biol (2008) 1.04
Comparison of human chromosome 6p25 with mouse chromosome 13 reveals a greatly expanded ov-serpin gene repertoire in the mouse. Genomics (2002) 1.03
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Differential effects of genotoxic stress on both concurrent body growth and gradual senescence in the adult zebrafish. Aging Cell (2007) 1.02
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Cytoplasmic dynein could be key to understanding neurodegeneration. Genome Biol (2008) 1.02
T regulatory cells control susceptibility to invasive pneumococcal pneumonia in mice. PLoS Pathog (2012) 1.01
Spectrum of ENU-induced mutations in phenotype-driven and gene-driven screens in the mouse. Environ Mol Mutagen (2007) 1.01
HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants. PLoS Genet (2011) 0.99
An ENU-induced mutation in the Ankrd11 gene results in an osteopenia-like phenotype in the mouse mutant Yoda. Physiol Genomics (2007) 0.99
Large-scale pathways-based association study in amyotrophic lateral sclerosis. Brain (2007) 0.98