Published in Mamm Genome on January 24, 2009
The mammalian ovary from genesis to revelation. Endocr Rev (2009) 2.31
Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney. Kidney Int (2010) 1.54
DICER1 mutations in childhood cystic nephroma and its relationship to DICER1-renal sarcoma. Mod Pathol (2014) 1.48
microRNAs and genetic diseases. Pathogenetics (2009) 1.32
Genetics of congenital anomalies of the kidney and urinary tract. Pediatr Nephrol (2010) 1.25
The regulatory role of Dicer in folliculogenesis in mice. Mol Cell Endocrinol (2009) 1.20
MicroRNAs regulate renal tubule maturation through modulation of Pkd1. J Am Soc Nephrol (2012) 1.12
A dosage-dependent pleiotropic role of Dicer in prostate cancer growth and metastasis. Oncogene (2013) 1.04
Regulation of WNK1 expression by miR-192 and aldosterone. J Am Soc Nephrol (2010) 0.97
MicroRNAs in kidney function and disease. Transl Res (2011) 0.96
Minireview: The roles of small RNA pathways in reproductive medicine. Mol Endocrinol (2011) 0.92
Role of Dicer in female fertility. Trends Endocrinol Metab (2009) 0.92
Dicer ablation impairs prostate stem cell activity and causes prostate atrophy. Stem Cells (2010) 0.90
Network analysis of a Pkd1-mouse model of autosomal dominant polycystic kidney disease identifies HNF4α as a disease modifier. PLoS Genet (2012) 0.90
Inactivation of Dicer1 in Steroidogenic factor 1-positive cells reveals tissue-specific requirement for Dicer1 in adrenal, testis, and ovary. BMC Dev Biol (2010) 0.88
The regulation and function of microRNAs in kidney diseases. IUBMB Life (2013) 0.87
Pediatric cystic nephromas: distinctive features and frequent DICER1 mutations. Hum Pathol (2015) 0.83
MicroRNAs in renal development. Pediatr Nephrol (2012) 0.83
Understanding the role of maternal diet on kidney development; an opportunity to improve cardiovascular and renal health for future generations. Nutrients (2015) 0.83
Developmental programming of hypertension and kidney disease. Int J Nephrol (2012) 0.81
The role of Dicer1 in the male reproductive tract. Asian J Androl (2015) 0.80
Loss of Dgcr8-mediated microRNA expression in the kidney results in hydronephrosis and renal malformation. BMC Nephrol (2015) 0.80
Selective dicer suppression in the kidney alters GSK3β/β-catenin pathways promoting a glomerulocystic disease. PLoS One (2015) 0.80
An emerging role for microRNA in the regulation of endothelin-1. Front Physiol (2013) 0.80
MicroRNAs in the pathogenesis of cystic kidney disease. Curr Opin Pediatr (2015) 0.79
Cell- and developmental stage-specific Dicer1 ablation in the lung epithelium models cystic pleuropulmonary blastoma. J Pathol (2015) 0.79
Oocyte-somatic cell communication and microRNA function in the ovary. Ann Endocrinol (Paris) (2010) 0.79
microRNA biomarkers in cystic diseases. BMB Rep (2013) 0.78
miRNAs in mammalian ureteric bud development. Pediatr Nephrol (2014) 0.77
The ureteric bud epithelium: morphogenesis and roles in metanephric kidney patterning. Mol Reprod Dev (2015) 0.77
Research resources: comparative microRNA profiles in human corona radiata cells and cumulus oophorus cells detected by next-generation small RNA sequencing. PLoS One (2014) 0.77
Targeted sequencing of 96 renal developmental microRNAs in 1213 individuals from 980 families with congenital anomalies of the kidney and urinary tract. Nephrol Dial Transplant (2016) 0.76
microRNA-dependent temporal gene expression in the ureteric bud epithelium during mammalian kidney development. Dev Dyn (2014) 0.75
Small RNAs have a big effect on polycystic kidney disease. J Am Soc Nephrol (2012) 0.75
Mice lacking microRNAs in Pax8-expressing cells develop hypothyroidism and end-stage renal failure. BMC Mol Biol (2016) 0.75
A MicroRNA Cluster miR-23-24-27 Is Upregulated by Aldosterone in the Distal Kidney Nephron Where it Alters Sodium Transport. J Cell Physiol (2017) 0.75
New roles for Dicer in the nucleolus and its relevance to cancer. Cell Cycle (2017) 0.75
Dicer is essential for mouse development. Nat Genet (2003) 15.87
The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proc Natl Acad Sci U S A (2005) 8.33
Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs. Nat Genet (2006) 6.30
Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev Cell (2005) 4.91
Dicer function is essential for lung epithelium morphogenesis. Proc Natl Acad Sci U S A (2006) 4.87
Critical roles for Dicer in the female germline. Genes Dev (2007) 4.23
Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney. Development (2002) 4.18
Female development in mammals is regulated by Wnt-4 signalling. Nature (1999) 4.13
Requirement of Bmpr1a for Müllerian duct regression during male sexual development. Nat Genet (2002) 2.75
Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis. J Am Soc Nephrol (2008) 2.74
Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease. J Am Soc Nephrol (2008) 2.69
Role of fibroblast growth factor receptors 1 and 2 in the ureteric bud. Dev Biol (2004) 2.39
A transcriptional network in polycystic kidney disease. EMBO J (2004) 2.21
Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression. Genes Dev (1991) 2.20
Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice. J Clin Invest (2008) 2.15
Deletion of Dicer in somatic cells of the female reproductive tract causes sterility. Mol Endocrinol (2008) 1.91
Developmental genetics of the female reproductive tract in mammals. Nat Rev Genet (2003) 1.78
Genetic analysis of the Müllerian-inhibiting substance signal transduction pathway in mammalian sexual differentiation. Genes Dev (1996) 1.75
Dicer1 is essential for female fertility and normal development of the female reproductive system. Endocrinology (2008) 1.71
Granulosa cell-specific inactivation of follistatin causes female fertility defects. Mol Endocrinol (2003) 1.62
TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population. Development (2004) 1.56
Severe urinary concentrating defect in renal collecting duct-selective AQP2 conditional-knockout mice. Proc Natl Acad Sci U S A (2006) 1.52
Dicer1 is required for differentiation of the mouse male germline. Biol Reprod (2008) 1.52
Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4. Development (2008) 1.42
Cellular mechanisms of Müllerian duct formation in the mouse. Dev Biol (2007) 1.36
Tissue-specific RNAi reveals that WT1 expression in nurse cells controls germ cell survival and spermatogenesis. Genes Dev (2006) 1.34
Requirement of Lim1 for female reproductive tract development. Development (2003) 1.29
Tailbud-derived mesenchyme promotes urinary tract segmentation via BMP4 signaling. Development (2007) 1.23
Novel phenotypes identified by plasma biochemical screening in the mouse. Mamm Genome (2002) 1.22
Regulation of Wolffian duct development. Horm Res (2006) 1.21
Genetic studies of the AMH/MIS signaling pathway for Müllerian duct regression. Mol Cell Endocrinol (2003) 1.07
The origin of the Mullerian duct in chick and mouse. Dev Biol (2006) 1.05
Sfrp1 and Sfrp2 are required for normal male sexual development in mice. Dev Biol (2008) 1.04
The critical time window for androgen-dependent development of the Wolffian duct in the rat. Endocrinology (2007) 1.01
Regulation of c-Ret in the developing kidney is responsive to Pax2 gene dosage. Hum Mol Genet (2006) 1.00
Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli. Hum Mol Genet (2008) 0.99
Galectin-3 associates with the primary cilium and modulates cyst growth in congenital polycystic kidney disease. Am J Pathol (2006) 0.92
Paracrine-mediated apoptosis in reproductive tract development. Dev Biol (1999) 0.89
Effects of granulosa cell-specific deletion of Rb in Inha-alpha null female mice. Endocrinology (2007) 0.84
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell (2007) 12.72
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet (2003) 12.16
The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proc Natl Acad Sci U S A (2005) 8.33
MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Nat Genet (2004) 6.11
TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. Science (2005) 5.56
Successes and challenges of HIV prevention in men who have sex with men. Lancet (2012) 4.94
Dicer function is essential for lung epithelium morphogenesis. Proc Natl Acad Sci U S A (2006) 4.87
Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity. J Exp Med (2008) 4.68
Overexpression of Fto leads to increased food intake and results in obesity. Nat Genet (2010) 4.37
Chd1 regulates open chromatin and pluripotency of embryonic stem cells. Nature (2009) 4.13
Distinct stem cell populations regenerate the follicle and interfollicular epidermis. Dev Cell (2005) 3.98
BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing. Nat Genet (2006) 3.79
The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development. Nature (2005) 3.78
A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell (2013) 3.53
RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proc Natl Acad Sci U S A (2003) 3.48
Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination. Neuron (2010) 3.37
Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus. J Neurosci (2008) 3.33
Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis. PLoS Genet (2006) 3.27
Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans. Cell (2007) 3.06
Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles. J Physiol (2009) 3.02
Epidermal stem cells arise from the hair follicle after wounding. FASEB J (2007) 2.81
MicroRNA expression is required for pancreatic islet cell genesis in the mouse. Diabetes (2007) 2.80
Essential role for Dicer during skeletal muscle development. Dev Biol (2007) 2.76
EuroPhenome: a repository for high-throughput mouse phenotyping data. Nucleic Acids Res (2009) 2.72
Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease. J Am Soc Nephrol (2008) 2.69
The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm Genome (2012) 2.65
The transmembrane protein TMEM16A is required for normal development of the murine trachea. Dev Biol (2008) 2.61
SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia. J Clin Invest (2011) 2.60
Transmembrane protein 16A (TMEM16A) is a Ca2+-regulated Cl- secretory channel in mouse airways. J Biol Chem (2009) 2.59
Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. J Neurosci (2008) 2.50
Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs. PLoS Genet (2013) 2.46
Studies on expression and function of the TMEM16A calcium-activated chloride channel. Proc Natl Acad Sci U S A (2009) 2.33
Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration. Proc Natl Acad Sci U S A (2008) 2.32
SW-ARRAY: a dynamic programming solution for the identification of copy-number changes in genomic DNA using array comparative genome hybridization data. Nucleic Acids Res (2005) 2.30
The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons. Nat Neurosci (2012) 2.28
Impaired synaptic plasticity and motor learning in mice with a point mutation implicated in human speech deficits. Curr Biol (2008) 2.27
IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2. Science (2012) 2.25
Mouse large-scale phenotyping initiatives: overview of the European Mouse Disease Clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project. Mamm Genome (2012) 2.12
Loss of TMEM16A causes a defect in epithelial Ca2+-dependent chloride transport. J Biol Chem (2009) 2.07
Podocyte-specific expression of angiopoietin-2 causes proteinuria and apoptosis of glomerular endothelia. J Am Soc Nephrol (2007) 2.06
A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains. Genome Biol (2013) 2.04
LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages. FASEB J (2009) 1.99
TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression. Cancer Res (2012) 1.98
Identification of an imprinting control region affecting the expression of all transcripts in the Gnas cluster. Nat Genet (2006) 1.98
Rapid creation and quantitative monitoring of high coverage shRNA libraries. Nat Methods (2009) 1.98
A protocol for high-throughput phenotyping, suitable for quantitative trait analysis in mice. Mamm Genome (2006) 1.96
Expanded RNA-binding activities of mammalian Argonaute 2. Nucleic Acids Res (2009) 1.94
Tmem16A encodes the Ca2+-activated Cl- channel in mouse submandibular salivary gland acinar cells. J Biol Chem (2010) 1.93
Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: implications for disk degeneration and chordoma formation. Dev Dyn (2008) 1.91
TMEM16 proteins produce volume-regulated chloride currents that are reduced in mice lacking TMEM16A. J Biol Chem (2009) 1.89
Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesis. Gastroenterology (2009) 1.86
Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux. Am J Hum Genet (2007) 1.85
Renal tract malformations: perspectives for nephrologists. Nat Clin Pract Nephrol (2008) 1.83
Neurosurgery simulation in residency training: feasibility, cost, and educational benefit. Neurosurgery (2013) 1.83
A gene-driven ENU-based approach to generating an allelic series in any gene. Mamm Genome (2004) 1.82
Precursor microRNA-programmed silencing complex assembly pathways in mammals. Mol Cell (2012) 1.81
A cis-acting control region is required exclusively for the tissue-specific imprinting of Gnas. Nat Genet (2004) 1.81
EMMA--mouse mutant resources for the international scientific community. Nucleic Acids Res (2009) 1.75
Fraser syndrome and mouse blebbed phenotype caused by mutations in FRAS1/Fras1 encoding a putative extracellular matrix protein. Nat Genet (2003) 1.71
Practical application of ontologies to annotate and analyse large scale raw mouse phenotype data. BMC Bioinformatics (2009) 1.70
Angiopoietin-1 therapy enhances fibrosis and inflammation following folic acid-induced acute renal injury. Kidney Int (2008) 1.70
Degeneration and regeneration of the intervertebral disc: lessons from development. Dis Model Mech (2010) 1.69
A resource for the conditional ablation of microRNAs in the mouse. Cell Rep (2012) 1.66
Mouse let-7 miRNA populations exhibit RNA editing that is constrained in the 5'-seed/ cleavage/anchor regions and stabilize predicted mmu-let-7a:mRNA duplexes. Genome Res (2008) 1.66
Centriolar satellites are assembly points for proteins implicated in human ciliopathies, including oral-facial-digital syndrome 1. J Cell Sci (2011) 1.64
Peritubular capillary loss after mouse acute nephrotoxicity correlates with down-regulation of vascular endothelial growth factor-A and hypoxia-inducible factor-1 alpha. Am J Pathol (2003) 1.63
Dicer ablation in oligodendrocytes provokes neuronal impairment in mice. Ann Neurol (2009) 1.62
The microRNA-processing enzyme dicer maintains juxtaglomerular cells. J Am Soc Nephrol (2010) 1.60
Analysis of microRNA knockouts in mice. Hum Mol Genet (2010) 1.59
ENU mutagenesis, a way forward to understand gene function. Annu Rev Genomics Hum Genet (2008) 1.59
Residual microRNA expression dictates the extent of inner ear development in conditional Dicer knockout mice. Dev Biol (2009) 1.55
Risk factors for mortality from imported falciparum malaria in the United Kingdom over 20 years: an observational study. BMJ (2012) 1.54
Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion. J Biol Chem (2009) 1.53
Dicer1 is required for differentiation of the mouse male germline. Biol Reprod (2008) 1.52
Identification of a new gene mutated in Fraser syndrome and mouse myelencephalic blebs. Nat Genet (2005) 1.51
Cell lineage analysis demonstrates an endodermal origin of the distal urethra and perineum. Dev Biol (2008) 1.51
Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons. Neuron (2012) 1.50
Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP. EMBO J (2005) 1.49
Base composition of mononucleotide runs affects DNA polymerase slippage and removal of frameshift intermediates by mismatch repair in Saccharomyces cerevisiae. Mol Cell Biol (2002) 1.49
A Tcf4-positive mesodermal population provides a prepattern for vertebrate limb muscle patterning. Dev Cell (2003) 1.48
Vaginal prostaglandin (PGE2 and PGF2a) for induction of labour at term. Cochrane Database Syst Rev (2009) 1.47
MicroRNAs and endocrine biology. J Endocrinol (2005) 1.47
Pkd1l1 establishes left-right asymmetry and physically interacts with Pkd2. Development (2011) 1.47
Convergent extension movements and ciliary function are mediated by ofd1, a zebrafish orthologue of the human oral-facial-digital type 1 syndrome gene. Hum Mol Genet (2008) 1.46
OFD1 is a centrosomal/basal body protein expressed during mesenchymal-epithelial transition in human nephrogenesis. J Am Soc Nephrol (2004) 1.43