Published in J Neurochem on March 01, 2005
Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor. EMBO J (2006) 8.12
Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis. Nature (2010) 4.10
Pannexin 1 in erythrocytes: function without a gap. Proc Natl Acad Sci U S A (2006) 4.03
The role of pannexin 1 hemichannels in ATP release and cell-cell communication in mouse taste buds. Proc Natl Acad Sci U S A (2007) 4.01
Pannexin1 is part of the pore forming unit of the P2X(7) receptor death complex. FEBS Lett (2007) 3.19
The Concise Guide to PHARMACOLOGY 2013/14: ion channels. Br J Pharmacol (2013) 3.03
The pannexin 1 channel activates the inflammasome in neurons and astrocytes. J Biol Chem (2009) 2.90
Probenecid, a gout remedy, inhibits pannexin 1 channels. Am J Physiol Cell Physiol (2008) 2.79
Connexin channel permeability to cytoplasmic molecules. Prog Biophys Mol Biol (2007) 2.73
Afferent neurotransmission mediated by hemichannels in mammalian taste cells. EMBO J (2007) 2.51
P2X7 receptor-Pannexin1 complex: pharmacology and signaling. Am J Physiol Cell Physiol (2008) 2.49
Pannexin 1: the molecular substrate of astrocyte "hemichannels". J Neurosci (2009) 2.48
Pharmacological characterization of pannexin-1 currents expressed in mammalian cells. J Pharmacol Exp Ther (2008) 2.42
Connexin-specific cell-to-cell transfer of short interfering RNA by gap junctions. J Physiol (2005) 2.12
Unexpected link between an antibiotic, pannexin channels and apoptosis. Nature (2014) 2.06
ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner ear. Proc Natl Acad Sci U S A (2008) 2.01
UNC-1 regulates gap junctions important to locomotion in C. elegans. Curr Biol (2007) 1.91
Pannexin 1 contributes to ATP release in airway epithelia. Am J Respir Cell Mol Biol (2009) 1.89
Connexin and pannexin mediated cell-cell communication. Neuron Glia Biol (2007) 1.86
A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP. Am J Physiol Cell Physiol (2008) 1.86
Pannexin 1 is the conduit for low oxygen tension-induced ATP release from human erythrocytes. Am J Physiol Heart Circ Physiol (2010) 1.81
Connexin hemichannel-mediated CO2-dependent release of ATP in the medulla oblongata contributes to central respiratory chemosensitivity. J Physiol (2010) 1.81
ATP release from non-excitable cells. Purinergic Signal (2009) 1.78
Mechanisms of glutamate release from astrocytes. Neurochem Int (2007) 1.59
Mechanosensitive pannexin-1 channels mediate microvascular metastatic cell survival. Nat Cell Biol (2015) 1.51
Microglial morphology and dynamic behavior is regulated by ionotropic glutamatergic and GABAergic neurotransmission. PLoS One (2011) 1.49
Vesicular and conductive mechanisms of nucleotide release. Purinergic Signal (2012) 1.49
Glycosylation regulates pannexin intermixing and cellular localization. Mol Biol Cell (2009) 1.45
Connexins, pannexins, innexins: novel roles of "hemi-channels". Pflugers Arch (2008) 1.45
Pannexin1 and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other. J Biol Chem (2010) 1.39
Modulation of brain hemichannels and gap junction channels by pro-inflammatory agents and their possible role in neurodegeneration. Antioxid Redox Signal (2009) 1.34
Gap junctions: multifaceted regulators of embryonic cortical development. Trends Neurosci (2008) 1.34
Properties of mouse connexin 30.2 and human connexin 31.9 hemichannels: implications for atrioventricular conduction in the heart. Proc Natl Acad Sci U S A (2006) 1.32
Intercellular Ca(2+) waves: mechanisms and function. Physiol Rev (2012) 1.32
Elevated pressure triggers a physiological release of ATP from the retina: Possible role for pannexin hemichannels. Neuroscience (2008) 1.31
Alpha-hemolysin from Escherichia coli uses endogenous amplification through P2X receptor activation to induce hemolysis. Proc Natl Acad Sci U S A (2009) 1.30
Patch-clamp coordinated spectroscopy shows P2X2 receptor permeability dynamics require cytosolic domain rearrangements but not Panx-1 channels. Proc Natl Acad Sci U S A (2008) 1.28
Paracrine signaling through plasma membrane hemichannels. Biochim Biophys Acta (2012) 1.28
Mechanisms of ATP release and signalling in the blood vessel wall. Cardiovasc Res (2012) 1.27
SCAM analysis of Panx1 suggests a peculiar pore structure. J Gen Physiol (2010) 1.25
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ATP signaling is deficient in cultured Pannexin1-null mouse astrocytes. Glia (2012) 1.22
The P2X7 receptor-pannexin-1 complex decreases muscarinic acetylcholine receptor-mediated seizure susceptibility in mice. J Clin Invest (2011) 1.21
Diverse deafness mechanisms of connexin mutations revealed by studies using in vitro approaches and mouse models. Brain Res (2009) 1.20
Voltage dependence of ATP secretion in mammalian taste cells. J Gen Physiol (2008) 1.19
Neurons respond directly to mechanical deformation with pannexin-mediated ATP release and autostimulation of P2X7 receptors. J Physiol (2012) 1.17
Gap junctional communication in morphogenesis. Prog Biophys Mol Biol (2007) 1.16
The ATP permeability of pannexin 1 channels in a heterologous system and in mammalian taste cells is dispensable. J Cell Sci (2012) 1.16
High resolution map of Caenorhabditis elegans gap junction proteins. Dev Dyn (2009) 1.14
Connexins and pannexins: Coordinating cellular communication in the testis and epididymis. Spermatogenesis (2011) 1.13
Action potential-enhanced ATP release from taste cells through hemichannels. J Neurophysiol (2010) 1.13
Rho-family GTPases modulate Ca(2+) -dependent ATP release from astrocytes. Am J Physiol Cell Physiol (2008) 1.13
Mefloquine blockade of Pannexin1 currents: resolution of a conflict. Cell Commun Adhes (2009) 1.12
Identification and characterization of pannexin expression in the mammalian cochlea. J Comp Neurol (2009) 1.10
Genetic ablation of Pannexin1 protects retinal neurons from ischemic injury. PLoS One (2012) 1.10
Structural and functional similarities of calcium homeostasis modulator 1 (CALHM1) ion channel with connexins, pannexins, and innexins. J Biol Chem (2013) 1.10
Connexin and pannexin hemichannels in inflammatory responses of glia and neurons. Brain Res (2012) 1.10
A comparative antibody analysis of pannexin1 expression in four rat brain regions reveals varying subcellular localizations. Front Pharmacol (2013) 1.09
Physiological mechanisms for the modulation of pannexin 1 channel activity. J Physiol (2012) 1.07
The human deafness-associated connexin 30 T5M mutation causes mild hearing loss and reduces biochemical coupling among cochlear non-sensory cells in knock-in mice. Hum Mol Genet (2010) 1.07
Mechanisms of ATP release by human trabecular meshwork cells, the enabling step in purinergic regulation of aqueous humor outflow. J Cell Physiol (2012) 1.06
Innexins form two types of channels. FEBS Lett (2007) 1.05
K+ depolarization evokes ATP, adenosine and glutamate release from glia in rat hippocampus: a microelectrode biosensor study. Br J Pharmacol (2012) 1.04
Expression and roles of pannexins in ATP release in the pituitary gland. Endocrinology (2011) 1.04
Oxygen-glucose deprivation induces ATP release via maxi-anion channels in astrocytes. Purinergic Signal (2007) 1.04
Pannexin 2 is expressed by postnatal hippocampal neural progenitors and modulates neuronal commitment. J Biol Chem (2010) 1.03
The membrane protein Pannexin1 forms two open-channel conformations depending on the mode of activation. Sci Signal (2014) 1.03
Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles. Front Pharmacol (2013) 1.02
Pathways for ATP release by bovine ciliary epithelial cells, the initial step in purinergic regulation of aqueous humor inflow. Am J Physiol Cell Physiol (2010) 1.02
Differentiating connexin hemichannels and pannexin channels in cellular ATP release. FEBS Lett (2014) 1.01
Pannexin 1 forms an anion-selective channel. Pflugers Arch (2012) 1.00
Pannexin 1 constitutes the large conductance cation channel of cardiac myocytes. J Biol Chem (2010) 1.00
Properties of connexin 46 hemichannels in dissociated lens fiber cells. Invest Ophthalmol Vis Sci (2011) 0.99
P2Y2 receptor activation opens pannexin-1 channels in rat carotid body type II cells: potential role in amplifying the neurotransmitter ATP. J Physiol (2012) 0.98
What is hidden in the pannexin treasure trove: the sneak peek and the guesswork. J Cell Mol Med (2006) 0.98
Connexin 43 is an emerging therapeutic target in ischemia/reperfusion injury, cardioprotection and neuroprotection. Pharmacol Ther (2015) 0.97
Connexin mimetic peptides inhibit Cx43 hemichannel opening triggered by voltage and intracellular Ca2+ elevation. Basic Res Cardiol (2012) 0.97
Rat nucleus accumbens core astrocytes modulate reward and the motivation to self-administer ethanol after abstinence. Neuropsychopharmacology (2014) 0.95
Expression of pannexin isoforms in the systemic murine arterial network. J Vasc Res (2012) 0.95
Neuroglial ATP release through innexin channels controls microglial cell movement to a nerve injury. J Gen Physiol (2010) 0.95
Is pannexin the pore associated with the P2X7 receptor? Naunyn Schmiedebergs Arch Pharmacol (2013) 0.95
Roles of gap junctions, connexins, and pannexins in epilepsy. Front Physiol (2014) 0.94
Connexin43 and pannexin1 channels in osteoblasts: who is the "hemichannel"? J Membr Biol (2012) 0.94
The bizarre pharmacology of the ATP release channel pannexin1. Neuropharmacology (2013) 0.93
Interactions of connexins with other membrane channels and transporters. Prog Biophys Mol Biol (2007) 0.93
Connexin channel modulators and their mechanisms of action. Neuropharmacology (2013) 0.93
Nature of plasmalemmal functional "hemichannels". Biochim Biophys Acta (2011) 0.93
Stimulated efflux of amino acids and glutathione from cultured hippocampal slices by omission of extracellular calcium: likely involvement of connexin hemichannels. J Biol Chem (2008) 0.93
Mechanisms of ATP release, the enabling step in purinergic dynamics. Cell Physiol Biochem (2011) 0.92
Extracellular osmolarity modulates G protein-coupled receptor-dependent ATP release from 1321N1 astrocytoma cells. Am J Physiol Cell Physiol (2009) 0.92
ATP release through pannexon channels. Philos Trans R Soc Lond B Biol Sci (2015) 0.92
Air-stimulated ATP release from keratinocytes occurs through connexin hemichannels. PLoS One (2013) 0.91
Contribution of pannexin1 to experimental autoimmune encephalomyelitis. PLoS One (2013) 0.91
Possible involvement of different connexin43 domains in plasma membrane permeabilization induced by ischemia-reperfusion. J Membr Biol (2007) 0.90
Regulation of cellular communication by signaling microdomains in the blood vessel wall. Pharmacol Rev (2014) 0.90
Large-conductance channel formation mediated by P2X7 receptor activation is regulated through distinct intracellular signaling pathways in peritoneal macrophages and 2BH4 cells. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.89
Pannexin protein expression in the rat middle cerebral artery. J Vasc Res (2012) 0.89
Metabotropic NMDA receptor signaling couples Src family kinases to pannexin-1 during excitotoxicity. Nat Neurosci (2016) 0.89
The role of pannexin hemichannels in the anoxic depolarization of hippocampal pyramidal cells. Brain (2010) 0.89
Pannexins, a family of gap junction proteins expressed in brain. Proc Natl Acad Sci U S A (2003) 3.96
Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behavior. Neuron (2007) 3.67
CKAMP44: a brain-specific protein attenuating short-term synaptic plasticity in the dentate gyrus. Science (2010) 3.17
Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal interneuron networks. Proc Natl Acad Sci U S A (2002) 2.92
New insights into the classification and nomenclature of cortical GABAergic interneurons. Nat Rev Neurosci (2013) 2.65
In vivo labeling of parvalbumin-positive interneurons and analysis of electrical coupling in identified neurons. J Neurosci (2002) 2.38
Targeted whole-cell recordings in the mammalian brain in vivo. Neuron (2003) 2.35
Hippocampal theta rhythm and its coupling with gamma oscillations require fast inhibition onto parvalbumin-positive interneurons. Proc Natl Acad Sci U S A (2009) 2.34
Connexin36 mediates spike synchrony in olfactory bulb glomeruli. Neuron (2005) 2.26
NMDA receptor ablation on parvalbumin-positive interneurons impairs hippocampal synchrony, spatial representations, and working memory. Neuron (2010) 2.21
Cell-cell communication beyond connexins: the pannexin channels. Physiology (Bethesda) (2006) 2.13
High-frequency network oscillations in cerebellar cortex. Neuron (2008) 2.12
Functional characterization of intrinsic cholinergic interneurons in the cortex. J Neurosci (2007) 2.08
A novel network of multipolar bursting interneurons generates theta frequency oscillations in neocortex. Neuron (2003) 2.05
ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner ear. Proc Natl Acad Sci U S A (2008) 2.01
Differential involvement of oriens/pyramidale interneurones in hippocampal network oscillations in vitro. J Physiol (2004) 2.00
Parvalbumin-containing fast-spiking basket cells generate the field potential oscillations induced by cholinergic receptor activation in the hippocampus. J Neurosci (2010) 1.93
Ca2+ buffer saturation underlies paired pulse facilitation in calbindin-D28k-containing terminals. Neuron (2003) 1.88
A role for fast rhythmic bursting neurons in cortical gamma oscillations in vitro. Proc Natl Acad Sci U S A (2004) 1.80
GABAergic interneurons shape the functional maturation of the cortex. Neuron (2013) 1.79
Neurogenesis and widespread forebrain migration of distinct GABAergic neurons from the postnatal subventricular zone. Proc Natl Acad Sci U S A (2008) 1.78
Contribution of hippocampal and extra-hippocampal NR2B-containing NMDA receptors to performance on spatial learning tasks. Neuron (2008) 1.78
Orthogonal arrangement of rhythm-generating microcircuits in the hippocampus. Proc Natl Acad Sci U S A (2005) 1.71
Role of olivary electrical coupling in cerebellar motor learning. Neuron (2008) 1.67
Pannexin1 and Pannexin2 expression in the developing and mature rat brain. Brain Res Mol Brain Res (2005) 1.67
Long-range-projecting GABAergic neurons modulate inhibition in hippocampus and entorhinal cortex. Science (2012) 1.58
Pannexins in ischemia-induced neurodegeneration. Proc Natl Acad Sci U S A (2011) 1.55
Malignant deep brain stimulation-withdrawal syndrome in a patient with Parkinson's disease. Mov Disord (2013) 1.51
Specific gene transfer to neurons, endothelial cells and hematopoietic progenitors with lentiviral vectors. Nat Methods (2010) 1.48
The integrity of cholinergic basal forebrain neurons depends on expression of Nkx2-1. Eur J Neurosci (2011) 1.46
Excitotoxicity in vitro by NR2A- and NR2B-containing NMDA receptors. Neuropharmacology (2007) 1.44
Contrasting roles of axonal (pyramidal cell) and dendritic (interneuron) electrical coupling in the generation of neuronal network oscillations. Proc Natl Acad Sci U S A (2003) 1.38
Serotonin 3A receptor subtype as an early and protracted marker of cortical interneuron subpopulations. Cereb Cortex (2010) 1.33
Electrical synapses: a dynamic signaling system that shapes the activity of neuronal networks. Biochim Biophys Acta (2004) 1.31
GABAergic excitation in the basolateral amygdala. J Neurosci (2006) 1.30
A molecular basis of analgesic tolerance to cannabinoids. J Neurosci (2007) 1.28
Two calretinin-positive GABAergic cell types in layer 2/3 of the mouse neocortex provide different forms of inhibition. Cereb Cortex (2008) 1.28
Connexin36 mediates gap junctional coupling of alpha-ganglion cells in mouse retina. J Comp Neurol (2005) 1.26
Connexin30 mutations responsible for hidrotic ectodermal dysplasia cause abnormal hemichannel activity. Hum Mol Genet (2004) 1.23
Effects of electrically coupled inhibitory networks on local neuronal responses to intracortical microstimulation. J Neurophysiol (2006) 1.22
The N-terminal region of reelin regulates postnatal dendritic maturation of cortical pyramidal neurons. Proc Natl Acad Sci U S A (2009) 1.22
Bergmann glial AMPA receptors are required for fine motor coordination. Science (2012) 1.18
Expression of connexin36 in cone pedicles and OFF-cone bipolar cells of the mouse retina. J Neurosci (2004) 1.18
Transient depression of excitatory synapses on interneurons contributes to epileptiform bursts during gamma oscillations in the mouse hippocampal slice. J Neurophysiol (2005) 1.18
Diazepam binding inhibitor promotes progenitor proliferation in the postnatal SVZ by reducing GABA signaling. Cell Stem Cell (2012) 1.17
Sharp wave-like activity in the hippocampus in vitro in mice lacking the gap junction protein connexin 36. J Neurophysiol (2003) 1.16
Features of neuronal synchrony in mouse visual cortex. J Neurophysiol (2003) 1.16
Regulation of body temperature and neuroprotection by endogenous interleukin-6 in cerebral ischemia. J Cereb Blood Flow Metab (2003) 1.13
Dissociation of decision-making under ambiguity and decision-making under risk in patients with Parkinson's disease: a neuropsychological and psychophysiological study. Neuropsychologia (2009) 1.12
Two variants of the rat brain sodium-driven chloride bicarbonate exchanger (NCBE): developmental expression and addition of a PDZ motif. Eur J Neurosci (2003) 1.10
The long and short of GABAergic neurons. Curr Opin Neurobiol (2013) 1.09
Hemichannels in cerebral ischemia. Curr Mol Med (2009) 1.07
Gene expression analysis of in vivo fluorescent cells. PLoS One (2007) 1.06
Increased subventricular zone-derived cortical neurogenesis after ischemic lesion. Exp Neurol (2010) 1.05
Analysis of the effects of cannabinoids on identified synaptic connections in the caudate-putamen by paired recordings in transgenic mice. J Physiol (2006) 1.04
Input-output features of anatomically identified CA3 neurons during hippocampal sharp wave/ripple oscillation in vitro. J Neurosci (2013) 1.00
Functional outcome of pannexin-deficient mice after cerebral ischemia. Channels (Austin) (2012) 0.99
The role of electrical signaling via gap junctions in the generation of fast network oscillations. Brain Res Bull (2003) 0.99
Thyroid hormone is required for hypothalamic neurons regulating cardiovascular functions. J Clin Invest (2012) 0.98
Task-specific modulation of effective connectivity during two simple unimanual motor tasks: a 122-channel EEG study. Neuroimage (2011) 0.97
A reporter allele for investigating connexin 26 gene expression in the mouse brain. Eur J Neurosci (2003) 0.96
Mice with genetically altered glutamate receptors as models of schizophrenia: a comprehensive review. Neurosci Biobehav Rev (2009) 0.94
Major signaling pathways in migrating neuroblasts. Front Mol Neurosci (2009) 0.94
Molecular diversity of neocortical GABAergic interneurones. J Physiol (2004) 0.93
EphA4 preserves postnatal and adult neural stem cells in an undifferentiated state in vivo. J Cell Sci (2011) 0.93
Augmented hippocampal ripple oscillations in mice with reduced fast excitation onto parvalbumin-positive cells. J Neurosci (2009) 0.93
Endocannabinoid-mediated long-term depression of afferent excitatory synapses in hippocampal pyramidal cells and GABAergic interneurons. J Neurosci (2012) 0.92
Gap junctions between interneurons are required for normal spatial coding in the hippocampus and short-term spatial memory. J Neurosci (2011) 0.92
In vivo evidence for the involvement of the carboxy terminal domain in assembling connexin 36 at the electrical synapse. Mol Cell Neurosci (2010) 0.90
The effect of deep brain stimulation on the speech motor system. J Speech Lang Hear Res (2014) 0.90
Expression of Pannexin1 in the outer plexiform layer of the mouse retina and physiological impact of its knockout. J Comp Neurol (2013) 0.89
A versatile system for the neuronal subtype specific expression of lentiviral vectors. FASEB J (2009) 0.89
"Small axonless neurons": postnatally generated neocortical interneurons with delayed functional maturation. J Neurosci (2011) 0.88
Somato-dendritic nicotinic receptor responses recorded in vitro from the medial septal diagonal band complex of the rodent. J Physiol (2004) 0.87
5-HT(3A) receptor-bearing white matter interstitial GABAergic interneurons are functionally integrated into cortical and subcortical networks. J Neurosci (2011) 0.87
Connective tissue growth factor regulates interneuron survival and information processing in the olfactory bulb. Neuron (2013) 0.85
Subventricular zone-derived neuroblasts use vasculature as a scaffold to migrate radially to the cortex in neonatal mice. Cereb Cortex (2011) 0.85
Subthalamic stimulation modulates self-estimation of patients with Parkinson's disease and induces risk-seeking behaviour. Brain (2013) 0.85
A new rechargeable device for deep brain stimulation: a prospective patient satisfaction survey. Eur Neurol (2013) 0.85
GluN2B-containing NMDA receptors promote wiring of adult-born neurons into olfactory bulb circuits. J Neurosci (2012) 0.84
Signaling involved in neurite outgrowth of postnatally born subventricular zone neurons in vitro. BMC Neurosci (2010) 0.83
Signaling in migrating neurons: from molecules to networks. Front Neurosci (2011) 0.83
Synaptic NR2A- but not NR2B-Containing NMDA Receptors Increase with Blockade of Ionotropic Glutamate Receptors. Front Mol Neurosci (2009) 0.83
AII amacrine cells discriminate between heterocellular and homocellular locations when assembling connexin36-containing gap junctions. J Cell Sci (2014) 0.82
Selective reduction of AMPA currents onto hippocampal interneurons impairs network oscillatory activity. PLoS One (2012) 0.81
Intracellular acidification in neurons induced by ammonium depends on KCC2 function. Eur J Neurosci (2006) 0.81
Impaired self-awareness of motor deficits in Parkinson's disease: association with motor asymmetry and motor phenotypes. Mov Disord (2012) 0.81
Connexin45 modulates the proliferation of transit-amplifying precursor cells in the mouse subventricular zone. Proc Natl Acad Sci U S A (2012) 0.80
Morphological and physiological properties of enhanced green fluorescent protein (EGFP)-expressing wide-field amacrine cells in the ChAT-EGFP mouse line. Eur J Neurosci (2013) 0.80
A mouse translocation associated with Caspr5-2 disruption and perinatal lethality. Mamm Genome (2008) 0.79
Enhanced dendritic action potential backpropagation in parvalbumin-positive basket cells during sharp wave activity. Neurochem Res (2010) 0.79
Connexin 36 promotes cortical spreading depolarization and ischemic brain damage. Brain Res (2012) 0.78
Dynamic changes in the transcriptional profile of subventricular zone-derived postnatally born neuroblasts. Mech Dev (2012) 0.78
Differential effects of dopaminergic medication on basic motor performance and executive functions in Parkinson's disease. Neuropsychologia (2012) 0.77
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Impaired path integration and grid cell spatial periodicity in mice lacking GluA1-containing AMPA receptors. J Neurosci (2014) 0.76
Long-term effect of robot-assisted treadmill walking reduces freezing of gait in Parkinson's disease patients: a pilot study. J Neurol (2012) 0.76