Published in Immunity on May 01, 2002
Development of all CD4 T lineages requires nuclear factor TOX. J Exp Med (2008) 1.94
Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR. Nat Immunol (2006) 1.41
The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes. Nat Immunol (2010) 1.28
Unraveling a revealing paradox: Why major histocompatibility complex I-signaled thymocytes "paradoxically" appear as CD4+8lo transitional cells during positive selection of CD8+ T cells. J Exp Med (2003) 1.10
Cd8 enhancer E8I and Runx factors regulate CD8α expression in activated CD8+ T cells. Proc Natl Acad Sci U S A (2011) 1.01
cAMP responsive element modulator (CREM) α mediates chromatin remodeling of CD8 during the generation of CD3+ CD4- CD8- T cells. J Biol Chem (2013) 0.94
cAMP-responsive element modulator α (CREMα) trans-represses the transmembrane glycoprotein CD8 and contributes to the generation of CD3+CD4-CD8- T cells in health and disease. J Biol Chem (2013) 0.89
The epigenetic stability of the locus control region-deficient IgH locus in mouse hybridoma cells is a clonally varying, heritable feature. Genetics (2004) 0.88
T cell development: bottoms-up. Immunity (2002) 0.85
The epigenetic landscape of lineage choice: lessons from the heritability of CD4 and CD8 expression. Curr Top Microbiol Immunol (2012) 0.84
Histone acetylation mediated by Brd1 is crucial for Cd8 gene activation during early thymocyte development. Nat Commun (2014) 0.79
The L2a element is a mouse CD8 silencer that interacts with MAR-binding proteins SATB1 and CDP. Mol Immunol (2010) 0.78
Epigenetic plasticity of Cd8a locus during CD8(+) T-cell development and effector differentiation and reprogramming. Nat Commun (2014) 0.78
Transcriptional control of CD4 and CD8 coreceptor expression during T cell development. Cell Mol Life Sci (2013) 0.76
Replication allows inactivation of a knocked-in locus control region in inappropriate cell lineages. Proc Natl Acad Sci U S A (2010) 0.76
Heritable Gene Regulation in the CD4:CD8 T Cell Lineage Choice. Front Immunol (2017) 0.75
Transgenic mice with hematopoietic and lymphoid specific expression of Cre. Eur J Immunol (2003) 5.73
The European dimension for the mouse genome mutagenesis program. Nat Genet (2004) 3.84
The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development. Nat Immunol (2009) 3.27
RalGDS is required for tumor formation in a model of skin carcinogenesis. Cancer Cell (2005) 3.09
Tyrosine kinase receptor RET is a key regulator of Peyer's patch organogenesis. Nature (2007) 2.65
Modulation of heterochromatin protein 1 dynamics in primary Mammalian cells. Science (2003) 2.61
Mll has a critical role in fetal and adult hematopoietic stem cell self-renewal. Cell Stem Cell (2007) 2.23
Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance. PLoS Biol (2006) 2.08
Vav1 transduces TCR signals required for LFA-1 function and cell polarization at the immunological synapse. Eur J Immunol (2003) 1.88
Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis. Cancer Res (2004) 1.81
The CD8alpha gene locus is regulated by the Ikaros family of proteins. Mol Cell (2002) 1.79
Vav1 transduces T cell receptor signals to the activation of phospholipase C-gamma1 via phosphoinositide 3-kinase-dependent and -independent pathways. J Exp Med (2002) 1.78
Novel binding partners of Ldb1 are required for haematopoietic development. Development (2006) 1.63
Trithorax-group protein ASH1 methylates histone H3 lysine 36. Gene (2007) 1.56
Degenerate self-reactive human T-cell receptor causes spontaneous autoimmune disease in mice. Nat Med (2004) 1.52
Determining disease intervention strategies using spatially resolved simulations. PLoS One (2013) 1.49
Vav1 transduces T cell receptor signals to the activation of the Ras/ERK pathway via LAT, Sos, and RasGRP1. J Biol Chem (2004) 1.42
Early growth response gene 2 (Egr-2) controls the self-tolerance of T cells and prevents the development of lupuslike autoimmune disease. J Exp Med (2008) 1.38
Identification of a macrophage-specific chromatin signature in the IL-10 locus. J Immunol (2005) 1.37
Dynamic imaging of experimental Leishmania donovani-induced hepatic granulomas detects Kupffer cell-restricted antigen presentation to antigen-specific CD8 T cells. PLoS Pathog (2010) 1.32
L-selectin shedding does not regulate constitutive T cell trafficking but controls the migration pathways of antigen-activated T lymphocytes. J Exp Med (2003) 1.32
ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses. Nat Immunol (2006) 1.31
Contribution of neural crest-derived cells in the embryonic and adult thymus. J Immunol (2008) 1.30
VE-Cadherin-mediated cell-cell interaction suppresses sprouting via signaling to MLC2 phosphorylation. Curr Biol (2009) 1.29
HP1-beta is required for development of the cerebral neocortex and neuromuscular junctions. J Cell Biol (2008) 1.27
Role of T and NK cells and IL7/IL7r interactions during neonatal maturation of lymph nodes. Proc Natl Acad Sci U S A (2006) 1.26
Noncontact optical imaging in mice with full angular coverage and automatic surface extraction. Appl Opt (2007) 1.23
Generalized immune activation as a direct result of activated CD4+ T cell killing. J Biol (2009) 1.22
IL-7-producing stromal cells are critical for lymph node remodeling. Blood (2012) 1.22
TEL-AML1 promotes development of specific hematopoietic lineages consistent with preleukemic activity. Blood (2004) 1.18
Continuous MLL-ENL expression is necessary to establish a "Hox Code" and maintain immortalization of hematopoietic progenitor cells. Cancer Res (2005) 1.18
Three-dimensional in vivo imaging of green fluorescent protein-expressing T cells in mice with noncontact fluorescence molecular tomography. Mol Imaging (2007) 1.15
Rac GTPases play critical roles in early T-cell development. Blood (2008) 1.13
IL7-hCD25 and IL7-Cre BAC transgenic mouse lines: new tools for analysis of IL-7 expressing cells. Genesis (2009) 1.12
Differential RET signaling pathways drive development of the enteric lymphoid and nervous systems. Sci Signal (2012) 1.11
The relative efficiency of acquisition of MHC:peptide complexes and cross-presentation depends on dendritic cell type. J Immunol (2008) 1.11
Spartan: a comprehensive tool for understanding uncertainty in simulations of biological systems. PLoS Comput Biol (2013) 1.09
Position effect variegation and imprinting of transgenes in lymphocytes. Nucleic Acids Res (2008) 1.05
Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation. J Immunol (2003) 1.03
Insulin induces SOCS-6 expression and its binding to the p85 monomer of phosphoinositide 3-kinase, resulting in improvement in glucose metabolism. J Biol Chem (2004) 1.03
Galectin-1-expressing stromal cells constitute a specific niche for pre-BII cell development in mouse bone marrow. Blood (2011) 1.00
RhoJ/TCL regulates endothelial motility and tube formation and modulates actomyosin contractility and focal adhesion numbers. Arterioscler Thromb Vasc Biol (2010) 1.00
Isolation and characterization of hematopoietic transcription factor complexes by in vivo biotinylation tagging and mass spectrometry. Ann N Y Acad Sci (2005) 1.00
Differential geminin requirement for proliferation of thymocytes and mature T cells. J Immunol (2010) 1.00
Chronic exposure to low levels of antigen in the periphery causes reversible functional impairment correlating with changes in CD5 levels in monoclonal CD8 T cells. J Immunol (2003) 0.99
Natural killer receptors: the burden of a name. J Exp Med (2010) 0.98
Geminin regulates cortical progenitor proliferation and differentiation. Stem Cells (2011) 0.95
Dual function of histone H3 lysine 36 methyltransferase ASH1 in regulation of Hox gene expression. PLoS One (2011) 0.95
IL-7: the global builder of the innate lymphoid network and beyond, one niche at a time. Semin Immunol (2012) 0.94
The AXH domain adopts alternative folds the solution structure of HBP1 AXH. Structure (2005) 0.93
Inhibition of receptor tyrosine kinases restores immunocompetence and improves immune-dependent chemotherapy against experimental leishmaniasis in mice. J Clin Invest (2010) 0.92
Dendritic cell functional properties in a three-dimensional tissue model of human lung mucosa. Am J Physiol Lung Cell Mol Physiol (2011) 0.91
Pre-TCR signaling and CD8 gene bivalent chromatin resolution during thymocyte development. J Immunol (2011) 0.89
Dendritic cells matured by inflammation induce CD86-dependent priming of naive CD8+ T cells in the absence of their cognate peptide antigen. J Immunol (2009) 0.89
Endothelial-Rac1 is not required for tumor angiogenesis unless alphavbeta3-integrin is absent. PLoS One (2010) 0.88
Gene regulation: kissing chromosomes. Nature (2005) 0.87
EphB-ephrin-B2 interactions are required for thymus migration during organogenesis. Proc Natl Acad Sci U S A (2010) 0.86
Killer cell Ig-like receptor and leukocyte Ig-like receptor transgenic mice exhibit tissue- and cell-specific transgene expression. J Immunol (2003) 0.86
Uses of the in vitro endothelial-fibroblast organotypic co-culture assay in angiogenesis research. Biochem Soc Trans (2011) 0.85
Regulation of early T cell development by the PHD finger of histone lysine methyltransferase ASH1. Biochem Biophys Res Commun (2007) 0.83
CD8 locus nuclear dynamics during thymocyte development. J Immunol (2010) 0.80
The influence of CD4 T-cell subsets on control of CD4 T-cell-mediated graft-versus-host disease. Immunology (2008) 0.80
Visualisation of lymphoid organ development. Methods Mol Biol (2010) 0.79
Cellular and molecular requirements in lymph node and Peyer's patch development. Prog Mol Biol Transl Sci (2010) 0.79
Inefficient clustering of tyrosine-phosphorylated proteins at the immunological synapse in response to an antagonist peptide. Eur J Immunol (2002) 0.79
Life without geminin. Cell Cycle (2010) 0.79
Human high mobility group box transcription factor 1 affects thymocyte development and transgene variegation. J Immunol (2005) 0.78
Involvement of neurons and retinoic acid in lymphatic development: new insights in increased nuchal translucency. Prenat Diagn (2014) 0.78
An essential role for the stalk region of CD8 beta in the coreceptor function of CD8. J Immunol (2009) 0.77
T cell proliferation and homeostasis: an emerging role for the cell cycle inhibitor geminin. Crit Rev Immunol (2011) 0.77
Application of tissue engineering to the immune system: development of artificial lymph nodes. Front Immunol (2012) 0.77
Replication allows inactivation of a knocked-in locus control region in inappropriate cell lineages. Proc Natl Acad Sci U S A (2010) 0.76
Modulation of the murine CD8 gene complex following the targeted integration of human CD2-locus control region sequences. J Immunol (2011) 0.76
Commentary on "lymphoid tissue inducer cells and the evolution of CD4 dependent high-affinity antibody responses". Prog Mol Biol Transl Sci (2010) 0.75
Correction: Determining disease intervention strategies using spatially resolved simulations. PLoS One (2015) 0.75
Thymocyte differentiation: it's time to bend a little. Nat Immunol (2002) 0.75
Shh! Shh! It's, oh, so quiet. Nat Immunol (2004) 0.75
Bronchodilating effect of combined therapy with ipratropium bromide and ondansetron in patients with COPD. Pulm Pharmacol Ther (2007) 0.75
Extending and Applying Spartan to Perform Temporal Sensitivity Analyses for Predicting Changes in Influential Biological Pathways in Computational Models. IEEE/ACM Trans Comput Biol Bioinform (2016) 0.75