Published in Biol Psychiatry on April 01, 2010
Critical reappraisal of a catechol-O-methyltransferase transversion variant in schizophrenia. Biol Psychiatry (2010) 1.38
Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet (2008) 30.94
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ (2009) 22.18
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Association between microdeletion and microduplication at 16p11.2 and autism. N Engl J Med (2008) 19.71
A common genetic variant is associated with adult and childhood obesity. Science (2006) 14.95
Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet (2007) 14.05
Power failure: why small sample size undermines the reliability of neuroscience. Nat Rev Neurosci (2013) 13.37
Systematic review of the empirical evidence of study publication bias and outcome reporting bias. PLoS One (2008) 13.32
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
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Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. Nat Genet (2007) 12.13
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol (2009) 11.80
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07
Letting the genome out of the bottle--will we get our wish? N Engl J Med (2008) 9.10
Deploying whole genome sequencing in clinical practice and public health: meeting the challenge one bin at a time. Genet Med (2011) 8.48
Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective. Cell (2005) 8.40
The case of the misleading funnel plot. BMJ (2006) 8.26
Implications of small effect sizes of individual genetic variants on the design and interpretation of genetic association studies of complex diseases. Am J Epidemiol (2006) 7.66
Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised trials. BMJ (2014) 7.21
Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials. BMJ (2011) 6.80
Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat Genet (2008) 6.71
Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model. Sci Transl Med (2012) 6.27
Sensitivity of between-study heterogeneity in meta-analysis: proposed metrics and empirical evaluation. Int J Epidemiol (2008) 5.88
Research grants: Conform and be funded. Nature (2012) 5.83
Correlation of quality measures with estimates of treatment effect in meta-analyses of randomized controlled trials. JAMA (2002) 5.81
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
Genomic screening and replication using the same data set in family-based association testing. Nat Genet (2005) 5.44
Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo. Proc Natl Acad Sci U S A (2003) 5.44
Assessment of claims of improved prediction beyond the Framingham risk score. JAMA (2009) 5.36
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet (2009) 5.32
Why current publication practices may distort science. PLoS Med (2008) 5.09
A navigator for human genome epidemiology. Nat Genet (2008) 5.07
Assessment of cumulative evidence on genetic associations: interim guidelines. Int J Epidemiol (2007) 4.96
The genetics of Alzheimer disease: back to the future. Neuron (2010) 4.91
Evaluation of networks of randomized trials. Stat Methods Med Res (2007) 4.70
Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. Am J Hum Genet (2008) 4.66
Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses. Nat Rev Neurosci (2008) 4.64
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet (2013) 4.62
Predictive ability of DNA microarrays for cancer outcomes and correlates: an empirical assessment. Lancet (2003) 4.58
Number of published systematic reviews and global burden of disease: database analysis. BMJ (2003) 4.53
Size matters: just how big is BIG?: Quantifying realistic sample size requirements for human genome epidemiology. Int J Epidemiol (2008) 4.53
The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations. Ann Intern Med (2015) 4.49
Neoadjuvant versus adjuvant systemic treatment in breast cancer: a meta-analysis. J Natl Cancer Inst (2005) 4.48
How many genes underlie the occurrence of common complex diseases in the population? Int J Epidemiol (2005) 4.46
Heterogeneity testing in meta-analysis of genome searches. Genet Epidemiol (2005) 4.45
Public availability of published research data in high-impact journals. PLoS One (2011) 4.41
Family-based association between Alzheimer's disease and variants in UBQLN1. N Engl J Med (2005) 4.34
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. PLoS Genet (2012) 4.27
Sodium and potassium intake and mortality among US adults: prospective data from the Third National Health and Nutrition Examination Survey. Arch Intern Med (2011) 4.22
Relative citation impact of various study designs in the health sciences. JAMA (2005) 4.19
Comparisons of established risk prediction models for cardiovascular disease: systematic review. BMJ (2012) 4.16
Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial. J Clin Epidemiol (2010) 4.10
The emergence of translational epidemiology: from scientific discovery to population health impact. Am J Epidemiol (2010) 4.04
Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity. Neuron (2007) 3.98
Methods for meta-analysis in genetic association studies: a review of their potential and pitfalls. Hum Genet (2007) 3.92
Predicting death: an empirical evaluation of predictive tools for mortality. Arch Intern Med (2011) 3.81
Seven new loci associated with age-related macular degeneration. Nat Genet (2013) 3.81
Relation between burden of disease and randomised evidence in sub-Saharan Africa: survey of research. BMJ (2002) 3.78
Can family history be used as a tool for public health and preventive medicine? Genet Med (2002) 3.76
Translation of highly promising basic science research into clinical applications. Am J Med (2003) 3.74
National Institutes of Health approaches to dissemination and implementation science: current and future directions. Am J Public Health (2012) 3.72
Influence of reported study design characteristics on intervention effect estimates from randomized, controlled trials. Ann Intern Med (2012) 3.63
Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial. Arch Neurol (2003) 3.58
Overlapping meta-analyses on the same topic: survey of published studies. BMJ (2013) 3.57
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol (2011) 3.52
Empirical evaluation of very large treatment effects of medical interventions. JAMA (2012) 3.48
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. Lancet (2012) 3.48
Assessing and reporting heterogeneity in treatment effects in clinical trials: a proposal. Trials (2010) 3.45
Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta. Neuron (2013) 3.43
Selective reporting biases in cancer prognostic factor studies. J Natl Cancer Inst (2005) 3.41
Meta-analysis in genome-wide association studies. Pharmacogenomics (2009) 3.39
Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study. Lancet Neurol (2011) 3.36
Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis. Am J Gastroenterol (2004) 3.28
A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions. Am J Hum Genet (2008) 3.25
Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein. Am J Pathol (2004) 3.24
Recommendations for returning genomic incidental findings? We need to talk! Genet Med (2013) 3.23
A road map for efficient and reliable human genome epidemiology. Nat Genet (2006) 3.21
In vivo imaging of partially reversible th17 cell-induced neuronal dysfunction in the course of encephalomyelitis. Immunity (2010) 3.18
Medicine. Life cycle of translational research for medical interventions. Science (2008) 3.12
What is the clinical utility of genetic testing? Genet Med (2006) 3.01