Published in Biochem Biophys Res Commun on March 20, 2010
Differentially altered Ca2+ regulation and Ca2+ permeability in Cx26 hemichannels formed by the A40V and G45E mutations that cause keratitis ichthyosis deafness syndrome. J Gen Physiol (2010) 1.45
GJB2 Gene Mutations in Syndromic Skin Diseases with Sensorineural Hearing Loss. Curr Genomics (2011) 0.96
Mutations in GRHL2 result in an autosomal-recessive ectodermal Dysplasia syndrome. Am J Hum Genet (2014) 0.90
Altered CO2 sensitivity of connexin26 mutant hemichannels in vitro. Physiol Rep (2016) 0.77
Connexin 26 (GJB2) mutation in an Argentinean patient with keratitis-ichthyosis-deafness (KID) syndrome: a case report. BMC Med Genet (2016) 0.77
Connexinopathies: a structural and functional glimpse. BMC Cell Biol (2016) 0.75
Keratitis-ichthyosis-deafness syndrome: first affected family reported in the Middle East. Int Med Case Rep J (2014) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
The cornified envelope: a model of cell death in the skin. Nat Rev Mol Cell Biol (2005) 6.27
TAp73 knockout shows genomic instability with infertility and tumor suppressor functions. Genes Dev (2008) 4.85
The HECT family of E3 ubiquitin ligases: multiple players in cancer development. Cancer Cell (2008) 3.35
Deficiency of PORCN, a regulator of Wnt signaling, is associated with focal dermal hypoplasia. Nat Genet (2007) 2.75
The ubiquitin-protein ligase Itch regulates p73 stability. EMBO J (2005) 2.38
The p53 family: guardians of maternal reproduction. Nat Rev Mol Cell Biol (2011) 2.13
Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway. Genes Dev (2010) 2.06
MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1. Circulation (2009) 2.05
Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death. Nat Med (2009) 2.03
The E3 ubiquitin ligase Itch controls the protein stability of p63. Proc Natl Acad Sci U S A (2006) 2.01
Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer. Proc Natl Acad Sci U S A (2012) 1.97
Recurrent mutations in kindlin-1, a novel keratinocyte focal contact protein, in the autosomal recessive skin fragility and photosensitivity disorder, Kindler syndrome. J Invest Dermatol (2004) 1.95
Functional association between Wwox tumor suppressor protein and p73, a p53 homolog. Proc Natl Acad Sci U S A (2004) 1.91
TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria. EMBO J (2005) 1.90
MiR-203 controls proliferation, migration and invasive potential of prostate cancer cell lines. Cell Cycle (2011) 1.89
Tissue transglutaminase does not affect fibrotic matrix stability or regression of liver fibrosis in mice. Gastroenterology (2011) 1.85
TAp63 and DeltaNp63 in cancer and epidermal development. Cell Cycle (2007) 1.84
Methotrexate treatment in juvenile localized scleroderma: a randomized, double-blind, placebo-controlled trial. Arthritis Rheum (2011) 1.83
The impact of p53 and p73 on aneuploidy and cancer. Trends Cell Biol (2008) 1.76
P6 acupressure effectiveness on acute vertiginous patients: a double blind randomized study. J Altern Complement Med (2012) 1.70
DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2. Proc Natl Acad Sci U S A (2007) 1.70
Extracellular matrix protein 1 gene (ECM1) mutations in lipoid proteinosis and genotype-phenotype correlation. J Invest Dermatol (2003) 1.67
microRNA-34a regulates neurite outgrowth, spinal morphology, and function. Proc Natl Acad Sci U S A (2011) 1.60
Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets. Proc Natl Acad Sci U S A (2011) 1.58
Regulation of the apoptosis-necrosis switch. Oncogene (2004) 1.54
FLASH and NPAT positive but not Coilin positive Cajal Bodies correlate with cell ploidy. Cell Cycle (2008) 1.52
p63, a story of mice and men. J Invest Dermatol (2011) 1.50
New p63 targets in keratinocytes identified by a genome-wide approach. EMBO J (2006) 1.50
Transglutaminase 2-/- mice reveal a phagocytosis-associated crosstalk between macrophages and apoptotic cells. Proc Natl Acad Sci U S A (2003) 1.48
The p73 gene is an anti-tumoral target of the RARbeta/gamma-selective retinoid tazarotene. J Invest Dermatol (2004) 1.48
Negative regulation of the Hippo pathway by E3 ubiquitin ligase ITCH is sufficient to promote tumorigenicity. Cancer Res (2011) 1.47
Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis. Nat Med (2009) 1.45
TAp73 depletion accelerates aging through metabolic dysregulation. Genes Dev (2012) 1.45
Netherton syndrome: disease expression and spectrum of SPINK5 mutations in 21 families. J Invest Dermatol (2002) 1.42
p73 induces apoptosis by different mechanisms. Biochem Biophys Res Commun (2005) 1.42
One, two, three--p53, p63, p73 and chemosensitivity. Drug Resist Updat (2007) 1.41
p63-microRNA feedback in keratinocyte senescence. Proc Natl Acad Sci U S A (2012) 1.41
Annular lichenoid dermatitis of youth. J Am Acad Dermatol (2003) 1.40
A novel recessive connexin 31 (GJB3) mutation in a case of erythrokeratodermia variabilis. J Invest Dermatol (2004) 1.39
Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms. Proc Natl Acad Sci U S A (2008) 1.39
Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration. Am J Pathol (2008) 1.38
p63 is upstream of IKK alpha in epidermal development. J Cell Sci (2006) 1.35
TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity. Proc Natl Acad Sci U S A (2009) 1.34
A homozygous missense mutation in TGM5 abolishes epidermal transglutaminase 5 activity and causes acral peeling skin syndrome. Am J Hum Genet (2005) 1.33
PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73. Mol Cell Biol (2004) 1.33
p73 in Cancer. Genes Cancer (2011) 1.33
GLS2 is transcriptionally regulated by p73 and contributes to neuronal differentiation. Cell Cycle (2013) 1.32
p53 is cleaved by caspases generating fragments localizing to mitochondria. J Biol Chem (2006) 1.30
Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15. Genes Dev (2013) 1.30
miR-7 and miR-214 are specifically expressed during neuroblastoma differentiation, cortical development and embryonic stem cells differentiation, and control neurite outgrowth in vitro. Biochem Biophys Res Commun (2010) 1.29
Transglutaminase-dependent RhoA activation and depletion by serotonin in vascular smooth muscle cells. J Biol Chem (2006) 1.27
p73 regulates maintenance of neural stem cell. Biochem Biophys Res Commun (2010) 1.25
Pemphigus autoantibodies generated through somatic mutations target the desmoglein-3 cis-interface. J Clin Invest (2012) 1.25
Ubiquitin-dependent degradation of p73 is inhibited by PML. J Exp Med (2004) 1.24
Epithelial transglutaminase 2 is needed for T cell interleukin-17 production and subsequent pulmonary inflammation and fibrosis in bleomycin-treated mice. J Exp Med (2011) 1.23
Treatment of severe pemphigus with rituximab: report of 12 cases and a review of the literature. Arch Dermatol (2007) 1.21
Desmethylclomipramine induces the accumulation of autophagy markers by blocking autophagic flux. J Cell Sci (2009) 1.20
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch. Proc Natl Acad Sci U S A (2007) 1.19
Roles for p53 and p73 during oligodendrocyte development. Development (2004) 1.18
GADD153 and 12-lipoxygenase mediate fenretinide-induced apoptosis of neuroblastoma. Cancer Res (2002) 1.16
A novel RGD-independent cel adhesion pathway mediated by fibronectin-bound tissue transglutaminase rescues cells from anoikis. J Biol Chem (2003) 1.14
miR-146a is modulated in human endothelial cell with aging. Atherosclerosis (2011) 1.14
E1A activates transcription of p73 and Noxa to induce apoptosis. J Biol Chem (2004) 1.14
Respiratory distress and perinatal lethality in Nedd4-2-deficient mice. Nat Commun (2011) 1.13
Transglutaminase 2 is needed for the formation of an efficient phagocyte portal in macrophages engulfing apoptotic cells. J Immunol (2009) 1.13
p63 regulates glutaminase 2 expression. Cell Cycle (2013) 1.12
Differential altered stability and transcriptional activity of ΔNp63 mutants in distinct ectodermal dysplasias. J Cell Sci (2011) 1.11
Role of transglutaminase 2 in glucose tolerance: knockout mice studies and a putative mutation in a MODY patient. FASEB J (2002) 1.11
Molecular basis of Kindler syndrome in Italy: novel and recurrent Alu/Alu recombination, splice site, nonsense, and frameshift mutations in the KIND1 gene. J Invest Dermatol (2006) 1.10
Itch self-polyubiquitylation occurs through lysine-63 linkages. Biochem Pharmacol (2008) 1.09
The antiapoptotic DeltaNp73 is degraded in a c-Jun-dependent manner upon genotoxic stress through the antizyme-mediated pathway. Proc Natl Acad Sci U S A (2010) 1.09
p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells. Neurosci Lett (2007) 1.08
Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2. Proc Natl Acad Sci U S A (2010) 1.08
p73: a multifunctional protein in neurobiology. Mol Neurobiol (2011) 1.07
Identification of NCF2/p67phox as a novel p53 target gene. Cell Cycle (2012) 1.07
Transglutaminase type II plays a protective role in hepatic injury. Am J Pathol (2003) 1.06
Chemotherapy-induced apoptosis in hepatocellular carcinoma involves the p53 family and is mediated via the extrinsic and the intrinsic pathway. Int J Cancer (2010) 1.05
Cell death pathology: cross-talk with autophagy and its clinical implications. Biochem Biophys Res Commun (2011) 1.04
miR-24 triggers epidermal differentiation by controlling actin adhesion and cell migration. J Cell Biol (2012) 1.04
Expression of transglutaminase 5 in normal and pathologic human epidermis. J Invest Dermatol (2002) 1.04
NF-kappaB inhibits T-cell activation-induced, p73-dependent cell death by induction of MDM2. Proc Natl Acad Sci U S A (2010) 1.03
Lysine-specific modifications of p53: a matter of life and death? Oncotarget (2013) 1.03
Cell death pathology: perspective for human diseases. Biochem Biophys Res Commun (2011) 1.03
PORCN mutations in focal dermal hypoplasia: coping with lethality. Hum Mutat (2009) 1.02
New antibodies recognizing p73: comparison with commercial antibodies. Biochem Biophys Res Commun (2005) 1.02
p73-alpha is capable of inducing scotin and ER stress. Oncogene (2004) 1.02
Mechanisms of free-radical induction in relation to fenretinide-induced apoptosis of neuroblastoma. J Cell Biochem (2003) 1.01
Regulation of the p73 protein stability and degradation. Biochem Biophys Res Commun (2005) 1.00
TGFbeta mediates activation of transglutaminase 2 in response to oxidative stress that leads to protein aggregation. FASEB J (2008) 1.00
Oxidative stress activation of miR-125b is part of the molecular switch for Hailey-Hailey disease manifestation. Exp Dermatol (2011) 1.00
Expression of GATA-3 in epidermis and hair follicle: relationship to p63. Biochem Biophys Res Commun (2007) 0.99
Calpain cleavage regulates the protein stability of p73. Biochem Biophys Res Commun (2005) 0.99
Inhibitor of apoptosis-stimulating protein of p53 (iASPP) prevents senescence and is required for epithelial stratification. Proc Natl Acad Sci U S A (2011) 0.99
Dominant negative (DeltaN) p63alpha induces drug resistance in hepatocellular carcinoma by interference with apoptosis signaling pathways. Biochem Biophys Res Commun (2010) 0.99
p63 the guardian of human reproduction. Cell Cycle (2012) 0.98
Congenital lupus erythematosus: case report and review of the literature. Pediatr Dermatol (2005) 0.98