Published in Spine J on March 29, 2010
The cellular and molecular biology of the intervertebral disc: A clinician's primer. J Can Chiropr Assoc (2014) 0.77
The measurement of observer agreement for categorical data. Biometrics (1977) 216.56
The Oswestry Disability Index. Spine (Phila Pa 1976) (2000) 15.42
Can comorbidity be measured by questionnaire rather than medical record review? Med Care (1996) 10.53
Interpreting change scores for pain and functional status in low back pain: towards international consensus regarding minimal important change. Spine (Phila Pa 1976) (2008) 6.88
The visual analogue pain intensity scale: what is moderate pain in millimetres? Pain (1997) 5.29
Good prognosis for low back pain when left untampered. A randomized clinical trial. Spine (Phila Pa 1976) (1995) 2.91
Challenging the cumulative injury model: positive effects of greater body mass on disc degeneration. Spine J (2009) 2.82
Individual factors, occupational loading, and physical exercise as predictors of sciatic pain. Spine (Phila Pa 1976) (2002) 2.13
Lack of effectiveness of bed rest for sciatica. N Engl J Med (1999) 1.82
Incidence of sciatic pain among men in machine operating, dynamic physical work, and sedentary work. A three-year follow-up. Spine (Phila Pa 1976) (1994) 1.75
Occupational driving and lumbar disc degeneration: a case-control study. Lancet (2002) 1.67
A randomized controlled trial of intensive neurophysiology education in chronic low back pain. Clin J Pain (2004) 1.43
An epidemiological study of the relationship between occupations and acute herniated lumbar intervertebral discs. Int J Epidemiol (1975) 1.39
An epidemiological study of acute herniated lumbar intervertebral discs. Rheumatol Rehabil (1975) 1.39
Cumulative occupational lumbar load and lumbar disc disease--results of a German multi-center case-control study (EPILIFT). BMC Musculoskelet Disord (2009) 1.36
Does early intervention with a light mobilization program reduce long-term sick leave for low back pain? Spine (Phila Pa 1976) (2000) 1.32
Magnetic resonance imaging of the lumbar spine: findings in female subjects from administrative and nursing professions. Spine (Phila Pa 1976) (2006) 0.98
The physician as disability advisor for patients with musculoskeletal complaints. Spine (Phila Pa 1976) (2005) 0.88
Lifetime exercise and disk degeneration: an MRI study of monozygotic twins. Med Sci Sports Exerc (1997) 0.87
The effects of anthropometrics, lifting strength, and physical activities in disc degeneration. Spine (Phila Pa 1976) (2007) 0.87
Back and leg complaints in relation to muscle strength in young men. Scand J Rehabil Med (1980) 0.86
Spontaneous onset of back pain. Clin J Pain (1998) 0.81
Leisure time physical activities and the results of surgery of lumbar disc herniation. Scand J Rehabil Med (1987) 0.78
Finding the missing heritability of complex diseases. Nature (2009) 67.95
MicroRNAs modulate hematopoietic lineage differentiation. Science (2003) 30.05
Genome-wide association study identifies novel breast cancer susceptibility loci. Nature (2007) 29.23
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet (2007) 21.18
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
A global double-fluorescent Cre reporter mouse. Genesis (2007) 17.86
Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet (2008) 17.65
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proc Natl Acad Sci U S A (2008) 17.41
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet (2008) 16.25
Replicating genotype-phenotype associations. Nature (2007) 16.11
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Statistics in medicine--reporting of subgroup analyses in clinical trials. N Engl J Med (2007) 12.55
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Incidental meniscal findings on knee MRI in middle-aged and elderly persons. N Engl J Med (2008) 8.40
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet (2009) 8.39
Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet (2013) 8.24
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Genetic risk prediction--are we there yet? N Engl J Med (2009) 7.30
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet (2009) 7.30
Diet quality and major chronic disease risk in men and women: moving toward improved dietary guidance. Am J Clin Nutr (2002) 6.96
Powerful SNP-set analysis for case-control genome-wide association studies. Am J Hum Genet (2010) 6.60
Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genet (2008) 6.22
Sex hormone-binding globulin and risk of type 2 diabetes in women and men. N Engl J Med (2009) 6.16
Sugar-sweetened beverages and genetic risk of obesity. N Engl J Med (2012) 5.98
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Performance of common genetic variants in breast-cancer risk models. N Engl J Med (2010) 5.79
A randomized trial of multivitamin supplements and HIV disease progression and mortality. N Engl J Med (2004) 5.68
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat Genet (2013) 5.58
Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet (2009) 5.14
Rheb promotes cell growth as a component of the insulin/TOR signalling network. Nat Cell Biol (2003) 5.01
A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. Nat Genet (2010) 4.89
Drosophila's insulin/PI3-kinase pathway coordinates cellular metabolism with nutritional conditions. Dev Cell (2002) 4.85
ABO blood group and the risk of pancreatic cancer. J Natl Cancer Inst (2009) 4.72
Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. Genes Dev (2003) 4.68
A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation. PLoS Genet (2008) 4.57
Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies. J Natl Cancer Inst (2010) 4.54
A new HPV-DNA test for cervical-cancer screening in developing regions: a cross-sectional study of clinical accuracy in rural China. Lancet Oncol (2008) 4.43
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Genome-wide association study of circulating vitamin D levels. Hum Mol Genet (2010) 4.07
A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. Nat Genet (2010) 3.93
Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet (2010) 3.91
Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet (2013) 3.81
Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development. Nat Cell Biol (2005) 3.80
Identification of a new prostate cancer susceptibility locus on chromosome 8q24. Nat Genet (2009) 3.76
Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet (2012) 3.69
Joint effects of common genetic variants on the risk for type 2 diabetes in U.S. men and women of European ancestry. Ann Intern Med (2009) 3.68
MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells. PLoS One (2009) 3.66
Telomere length, cigarette smoking, and bladder cancer risk in men and women. Cancer Epidemiol Biomarkers Prev (2007) 3.63
Cherry consumption and decreased risk of recurrent gout attacks. Arthritis Rheum (2012) 3.51
A prospective study of aspirin use and the risk for colorectal adenoma. Ann Intern Med (2004) 3.46
Population substructure and control selection in genome-wide association studies. PLoS One (2008) 3.44
Viscosupplementation for osteoarthritis of the knee. N Engl J Med (2015) 3.43
Methods for pooling results of epidemiologic studies: the Pooling Project of Prospective Studies of Diet and Cancer. Am J Epidemiol (2006) 3.41
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer. Nat Genet (2011) 3.37
Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes. Hum Mol Genet (2010) 3.24
Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart. J Biol Chem (2002) 3.22
A road map for efficient and reliable human genome epidemiology. Nat Genet (2006) 3.21
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Genome-wide association analysis identifies three new breast cancer susceptibility loci. Nat Genet (2012) 3.20
Alcohol intake and colorectal cancer: a pooled analysis of 8 cohort studies. Ann Intern Med (2004) 3.18
Histone methylation by PRC2 is inhibited by active chromatin marks. Mol Cell (2011) 3.14
Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia. Hum Mol Genet (2008) 3.14
A common 8q24 variant in prostate and breast cancer from a large nested case-control study. Cancer Res (2007) 3.08
Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. Nat Genet (2011) 3.07
A new statistic and its power to infer membership in a genome-wide association study using genotype frequencies. Nat Genet (2009) 3.06
Genome-wide association studies identify loci associated with age at menarche and age at natural menopause. Nat Genet (2009) 3.06
Novel breast cancer susceptibility locus at 9q31.2: results of a genome-wide association study. J Natl Cancer Inst (2011) 3.05
Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation. Proc Natl Acad Sci U S A (2012) 3.03
Sexual orientation, health risk factors, and physical functioning in the Nurses' Health Study II. J Womens Health (Larchmt) (2004) 3.01
Beyond odds ratios--communicating disease risk based on genetic profiles. Nat Rev Genet (2009) 3.01
Genome-wide and candidate gene association study of cigarette smoking behaviors. PLoS One (2009) 3.00
Plasma folate, vitamin B6, vitamin B12, homocysteine, and risk of breast cancer. J Natl Cancer Inst (2003) 2.92
Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample. PLoS One (2008) 2.92
Night-shift work and risk of colorectal cancer in the nurses' health study. J Natl Cancer Inst (2003) 2.87
Perinatal outcomes, including mother-to-child transmission of HIV, and child mortality and their association with maternal vitamin D status in Tanzania. J Infect Dis (2009) 2.84
Synovitis detected on magnetic resonance imaging and its relation to pain and cartilage loss in knee osteoarthritis. Ann Rheum Dis (2007) 2.81
Dietary fiber intake and risk of colorectal cancer: a pooled analysis of prospective cohort studies. JAMA (2005) 2.76
A prospective study of telomere length and the risk of skin cancer. J Invest Dermatol (2008) 2.75
Genomics: when the smoke clears ... Nature (2008) 2.72
Incidence of laparoscopically confirmed endometriosis by demographic, anthropometric, and lifestyle factors. Am J Epidemiol (2004) 2.72
Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium. Hum Mol Genet (2011) 2.72
Role of toll-like receptor signalling in Abeta uptake and clearance. Brain (2006) 2.70
A randomized controlled trial of Licartin for preventing hepatoma recurrence after liver transplantation. Hepatology (2007) 2.66
Use of tanning beds and incidence of skin cancer. J Clin Oncol (2012) 2.65
Outcome of percutaneous rupture of lumbar synovial cysts: a case series of 101 patients. Spine J (2009) 2.62
Effectiveness of bevacizumab with first-line combination chemotherapy for Medicare patients with stage IV colorectal cancer. J Clin Oncol (2012) 2.59
The effect of body weight on progression of knee osteoarthritis is dependent on alignment. Arthritis Rheum (2004) 2.58
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. Gastroenterology (2012) 2.57
The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth. Genes Dev (2007) 2.57
Transforming epidemiology for 21st century medicine and public health. Cancer Epidemiol Biomarkers Prev (2013) 2.56
Dairy foods, calcium, and colorectal cancer: a pooled analysis of 10 cohort studies. J Natl Cancer Inst (2004) 2.54
The relationship between cartilage loss on magnetic resonance imaging and radiographic progression in men and women with knee osteoarthritis. Arthritis Rheum (2005) 2.54
Genome-wide association study identifies new prostate cancer susceptibility loci. Hum Mol Genet (2011) 2.51
A prospective study of 2 major age-related macular degeneration susceptibility alleles and interactions with modifiable risk factors. Arch Ophthalmol (2007) 2.50
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11. Hum Mol Genet (2012) 2.45