Published in J Cell Sci on March 31, 2010
The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA. Nat Struct Mol Biol (2010) 1.85
BRCA2 localization to the midbody by filamin A regulates cep55 signaling and completion of cytokinesis. Dev Cell (2012) 1.02
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RAS promotes tumorigenesis through genomic instability induced by imbalanced expression of Aurora-A and BRCA2 in midbody during cytokinesis. Int J Cancer (2013) 0.89
The breast cancer susceptibility gene BRCA2 is required for the maintenance of telomere homeostasis. J Biol Chem (2011) 0.88
A mitotic function for the high-mobility group protein HMG20b regulated by its interaction with the BRC repeats of the BRCA2 tumor suppressor. Oncogene (2011) 0.86
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MRG15-mediated tethering of PALB2 to unperturbed chromatin protects active genes from genotoxic stress. Proc Natl Acad Sci U S A (2017) 0.76
BRCA2 minor transcript lacking exons 4-7 supports viability in mice and may account for survival of humans with a pathogenic biallelic mutation. Hum Mol Genet (2016) 0.75
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature (2010) 9.95
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals. Nat Methods (2008) 6.51
The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1. Curr Biol (2007) 6.17
Aurora B-mediated abscission checkpoint protects against tetraploidization. Cell (2009) 5.26
BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo. Curr Biol (2007) 5.17
Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science (2010) 4.69
Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments. Science (2011) 4.26
Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I. Nature (2006) 3.81
CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging. Nat Methods (2010) 2.93
Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells. Nat Cell Biol (2010) 2.91
Molecular control of animal cell cytokinesis. Nat Cell Biol (2012) 2.45
Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis. Dev Cell (2004) 2.39
Limiting amounts of centrosome material set centrosome size in C. elegans embryos. Curr Biol (2011) 2.25
Phosphatases: providing safe passage through mitotic exit. Nat Rev Mol Cell Biol (2011) 2.19
Kinetochore recruitment of two nucleolar proteins is required for homolog segregation in meiosis I. Dev Cell (2003) 2.17
Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation. PLoS Biol (2009) 2.02
Automated microscopy for high-content RNAi screening. J Cell Biol (2010) 1.87
The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA. Nat Struct Mol Biol (2010) 1.85
Cytokinetic abscission: cellular dynamics at the midbody. Trends Cell Biol (2009) 1.77
Polo-like kinase 1 reaches beyond mitosis--cytokinesis, DNA damage response, and development. Curr Opin Cell Biol (2008) 1.76
Mitotic phosphatases: from entry guards to exit guides. Trends Cell Biol (2009) 1.73
Relocation of the chromosomal passenger complex prevents mitotic checkpoint engagement at anaphase. Curr Biol (2010) 1.72
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly. J Cell Biol (2009) 1.64
The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. EMBO J (2013) 1.58
XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region. Proc Natl Acad Sci U S A (2011) 1.56
Tubulin polyglutamylation stimulates spastin-mediated microtubule severing. J Cell Biol (2010) 1.49
Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis. Nature (2012) 1.48
Division of the nucleolus and its release of CDC14 during anaphase of meiosis I depends on separase, SPO12, and SLK19. Dev Cell (2003) 1.48
Kinetic framework of spindle assembly checkpoint signalling. Nat Cell Biol (2013) 1.47
Targeting of the RhoGEF Ect2 to the equatorial membrane controls cleavage furrow formation during cytokinesis. Dev Cell (2011) 1.40
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The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis. J Cell Biol (2009) 1.29
Identification of substrates for cyclin dependent kinases. Adv Enzyme Regul (2010) 1.27
Expression and imaging of fluorescent proteins in the C. elegans gonad and early embryo. Methods Cell Biol (2008) 1.22
XMAP215 activity sets spindle length by controlling the total mass of spindle microtubules. Nat Cell Biol (2013) 1.20
RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells. EMBO J (2010) 1.19
Tandem affinity purification of functional TAP-tagged proteins from human cells. Nat Protoc (2007) 1.15
Automated live microscopy to study mitotic gene function in fluorescent reporter cell lines. Methods Mol Biol (2009) 1.12
Cdc48/p97-Ufd1-Npl4 antagonizes Aurora B during chromosome segregation in HeLa cells. J Cell Sci (2011) 1.11
Aurora B and Kif2A control microtubule length for assembly of a functional central spindle during anaphase. J Cell Biol (2013) 1.09
Unsupervised modeling of cell morphology dynamics for time-lapse microscopy. Nat Methods (2012) 1.09
ESCRT-III polymers in membrane neck constriction. Trends Cell Biol (2012) 1.07
Functional interaction between phosducin-like protein 2 and cytosolic chaperonin is essential for cytoskeletal protein function and cell cycle progression. Mol Biol Cell (2007) 1.06
Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores. J Cell Biol (2012) 1.03
SUN proteins facilitate the removal of membranes from chromatin during nuclear envelope breakdown. J Cell Biol (2014) 1.00
Cytokinetic abscission in animal cells. Semin Cell Dev Biol (2010) 0.99
Mps1 promotes rapid centromere accumulation of Aurora B. EMBO Rep (2012) 0.97
Aurora B kinase promotes cytokinesis by inducing centralspindlin oligomers that associate with the plasma membrane. Dev Cell (2015) 0.92
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Meiotic nuclear divisions in budding yeast require PP2A(Cdc55)-mediated antagonism of Net1 phosphorylation by Cdk. J Cell Biol (2011) 0.88
Recombination-mediated genetic engineering of large genomic DNA transgenes. Methods Mol Biol (2011) 0.87
The 'anaphase problem': how to disable the mitotic checkpoint when sisters split. Biochem Soc Trans (2010) 0.86
Correlative time-lapse imaging and electron microscopy to study abscission in HeLa cells. Methods Cell Biol (2010) 0.82
An evolutionary conserved checkpoint controls abscission timing. Cell Cycle (2009) 0.80
CellH5: a format for data exchange in high-content screening. Bioinformatics (2013) 0.78
Assays for mitotic chromosome condensation in live yeast and mammalian cells. Chromosome Res (2009) 0.76
Born equal: dual safeguards for daughter cell size symmetry. Cell (2013) 0.75