Published in Basic Res Cardiol on April 08, 2010
Loss of cadherin-binding proteins β-catenin and plakoglobin in the heart leads to gap junction remodeling and arrhythmogenesis. Mol Cell Biol (2012) 1.02
Desmoglein 2 mutant mice develop cardiac fibrosis and dilation. Basic Res Cardiol (2011) 0.91
Beyond cell adhesion: the role of armadillo proteins in the heart. Cell Signal (2012) 0.89
Xin proteins and intercalated disc maturation, signaling and diseases. Front Biosci (Landmark Ed) (2012) 0.88
EH-myomesin splice isoform is a novel marker for dilated cardiomyopathy. Basic Res Cardiol (2010) 0.84
Cardiomyocyte growth and sarcomerogenesis at the intercalated disc. Cell Mol Life Sci (2013) 0.84
Gene Mutations Resulting in the Development of ARVC/D Could Affect Cells of the Cardiac Conduction System. Front Physiol (2012) 0.83
Alterations in cell adhesion proteins and cardiomyopathy. World J Cardiol (2014) 0.80
Analysis of a Jup hypomorphic allele reveals a critical threshold for postnatal viability. Genesis (2012) 0.80
Expression and redistribution of β-catenin in the cardiac myocytes of left ventricle of spontaneously hypertensive rat. J Mol Histol (2013) 0.79
Adaptations of cytoarchitecture in human dilated cardiomyopathy. Biophys Rev (2014) 0.78
Breaking down protein degradation mechanisms in cardiac muscle. Trends Mol Med (2013) 0.78
Stimulation of HERG channel activity by β-catenin. PLoS One (2012) 0.77
Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes. Dev Cell (2005) 6.90
Subtypes of medulloblastoma have distinct developmental origins. Nature (2010) 5.94
Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev (2004) 4.78
Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties. Cell (2012) 4.58
Wnt signalling induces maturation of Paneth cells in intestinal crypts. Nat Cell Biol (2005) 4.34
Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche. Cell (2011) 4.04
Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation. Nat Immunol (2006) 3.98
The kinase domain of titin controls muscle gene expression and protein turnover. Science (2005) 3.68
The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway. Cell Stem Cell (2007) 3.54
Wnt/beta-catenin signaling controls development of the blood-brain barrier. J Cell Biol (2008) 3.22
HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci (2009) 3.18
Beta-catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse. Dev Biol (2006) 3.17
Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene. EMBO J (2002) 3.06
beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system. Dev Biol (2003) 2.85
Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells. Science (2004) 2.82
Wnt signaling regulates pancreatic beta cell proliferation. Proc Natl Acad Sci U S A (2007) 2.61
Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors. Proc Natl Acad Sci U S A (2007) 2.56
ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles. J Cell Biol (2005) 2.50
The Chlorella variabilis NC64A genome reveals adaptation to photosymbiosis, coevolution with viruses, and cryptic sex. Plant Cell (2010) 2.47
Stabilization of beta-catenin impacts pancreas growth. Development (2006) 2.44
Wnt-beta-catenin signaling initiates taste papilla development. Nat Genet (2006) 2.43
Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene. J Cell Sci (2007) 2.41
Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination. Cell (2006) 2.40
SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion. Nat Genet (2007) 2.39
Dclk1 distinguishes between tumor and normal stem cells in the intestine. Nat Genet (2012) 2.33
Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis. Dev Biol (2007) 2.26
Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A (2006) 2.25
β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas. Cancer Cell (2011) 2.17
Formation of multiple hearts in mice following deletion of beta-catenin in the embryonic endoderm. Dev Cell (2002) 2.14
Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signaling. J Clin Invest (2007) 2.12
Targeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death. Mol Cell Biol (2003) 2.07
Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice. Cancer Res (2002) 2.05
Inhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in ApcDelta716 mice. Proc Natl Acad Sci U S A (2008) 2.04
Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis. Nat Neurosci (2009) 2.03
The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling. Dev Cell (2010) 2.01
Hepatocarcinogenesis in mice with beta-catenin and Ha-ras gene mutations. Cancer Res (2004) 2.01
Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps. Cancer Res (2002) 2.00
Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice. Nat Genet (2003) 1.99
Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate. Development (2008) 1.96
Sequential myofibrillar breakdown accompanies mitotic division of mammalian cardiomyocytes. J Cell Sci (2004) 1.96
Wnt signals mediate a fate decision between otic placode and epidermis. Development (2006) 1.94
Beta-catenin regulates differentiation of respiratory epithelial cells in vivo. Am J Physiol Lung Cell Mol Physiol (2005) 1.93
Stabilization of beta-catenin in XY gonads causes male-to-female sex-reversal. Hum Mol Genet (2008) 1.90
Extracellular superoxide dismutase is a major determinant of nitric oxide bioavailability: in vivo and ex vivo evidence from ecSOD-deficient mice. Circ Res (2003) 1.89
WNT-3, expressed by motoneurons, regulates terminal arborization of neurotrophin-3-responsive spinal sensory neurons. Neuron (2002) 1.81
Activation of beta-catenin signaling by Rspo1 controls differentiation of the mammalian ovary. Hum Mol Genet (2008) 1.80
Subcellular targeting of metabolic enzymes to titin in heart muscle may be mediated by DRAL/FHL-2. J Cell Sci (2002) 1.77
Cardiac sodium channel Nav1.5 is regulated by a multiprotein complex composed of syntrophins and dystrophin. Circ Res (2006) 1.76
Induction of cardiogenesis in embryonic stem cells via downregulation of Notch1 signaling. Circ Res (2006) 1.75
Beta-catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation. Development (2003) 1.73
Two distinct classes of muscarinic action on hippocampal inhibitory synapses: M2-mediated direct suppression and M1/M3-mediated indirect suppression through endocannabinoid signalling. Eur J Neurosci (2004) 1.71
Activation of a HIF1alpha-PPARgamma axis underlies the integration of glycolytic and lipid anabolic pathways in pathologic cardiac hypertrophy. Cell Metab (2009) 1.69
Establishment of cardiac cytoarchitecture in the developing mouse heart. Dev Biol (2005) 1.68
The M-band: an elastic web that crosslinks thick filaments in the center of the sarcomere. Trends Cell Biol (2005) 1.67
Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon. Dev Biol (2005) 1.66
Wnt3a/beta-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation. Development (2007) 1.63
Lack of tumorigenesis in the mouse liver after adenovirus-mediated expression of a dominant stable mutant of beta-catenin. Cancer Res (2002) 1.62
Wt1 negatively regulates beta-catenin signaling during testis development. Development (2008) 1.61
JNK signaling promotes intestinal tumorigenesis through activation of mTOR complex 1 in Apc(Δ716) mice. Gastroenterology (2011) 1.61
Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis. Proc Natl Acad Sci U S A (2007) 1.60
Stromal fibroblasts activated by tumor cells promote angiogenesis in mouse gastric cancer. J Biol Chem (2008) 1.60
Hepatocellular carcinoma caused by loss of heterozygosity in Lkb1 gene knockout mice. Cancer Res (2002) 1.60
Homozygous inactivation of Sox9 causes complete XY sex reversal in mice. Biol Reprod (2005) 1.59
Dietary obesity-associated Hif1α activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system. Genes Dev (2012) 1.59
Is off-pump superior to conventional coronary artery bypass grafting in diabetic patients with multivessel disease? Eur J Cardiothorac Surg (2010) 1.59
Modulation of synaptic plasticity by physiological activation of M1 muscarinic acetylcholine receptors in the mouse hippocampus. J Neurosci (2005) 1.58
Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice. Circulation (2011) 1.57
Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis. Proc Natl Acad Sci U S A (2011) 1.57
Phases of canonical Wnt signaling during the development of mouse intestinal epithelium. Gastroenterology (2007) 1.55
Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb. Genes Dev (2003) 1.55
β-Catenin activation regulates tissue growth non-cell autonomously in the hair stem cell niche. Science (2014) 1.55
Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea. Proc Natl Acad Sci U S A (2012) 1.54
A novel desmocollin-2 mutation reveals insights into the molecular link between desmosomes and gap junctions. Heart Rhythm (2011) 1.54
Overexpression of angiotensinogen in the myocardium induces downregulation of the fatty acid oxidation pathway. J Mol Cell Cardiol (2006) 1.53
Dilated cardiomyopathy: a disease of the intercalated disc? Trends Cardiovasc Med (2003) 1.52
Mice lacking M2 and M3 muscarinic acetylcholine receptors are devoid of cholinergic smooth muscle contractions but still viable. J Neurosci (2002) 1.51
Wnt/β-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival. J Biol Chem (2011) 1.51
Misregulated Wnt/beta-catenin signaling leads to ovarian granulosa cell tumor development. Cancer Res (2005) 1.51
Stabilization of beta-catenin in the mouse zygote leads to premature epithelial-mesenchymal transition in the epiblast. Development (2004) 1.50
The genome of the polar eukaryotic microalga Coccomyxa subellipsoidea reveals traits of cold adaptation. Genome Biol (2012) 1.49
Carcinogenesis in mouse stomach by simultaneous activation of the Wnt signaling and prostaglandin E2 pathway. Gastroenterology (2006) 1.47
Reduced level of smoothened suppresses intestinal tumorigenesis by down-regulation of Wnt signaling. Gastroenterology (2009) 1.47
Potassium supplementation reduces cardiac and renal hypertrophy independent of blood pressure in DOCA/salt mice. Hypertension (2005) 1.46
FGF-2 controls the differentiation of resident cardiac precursors into functional cardiomyocytes. J Clin Invest (2005) 1.46
Activation of beta -catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias. Proc Natl Acad Sci U S A (2002) 1.44
From A to Z and back? Multicompartment proteins in the sarcomere. Trends Cell Biol (2005) 1.43
Hyperplastic gastric tumors induced by activated macrophages in COX-2/mPGES-1 transgenic mice. EMBO J (2004) 1.42
A genetic study of the role of the Wnt/beta-catenin signalling in Paneth cell differentiation. Dev Biol (2008) 1.42
Isoflurane postconditioning prevents opening of the mitochondrial permeability transition pore through inhibition of glycogen synthase kinase 3beta. Anesthesiology (2005) 1.41
Cyclooxygenase-2 expression in fibroblasts and endothelial cells of intestinal polyps. Cancer Res (2002) 1.39
Postsynaptic M1 and M3 receptors are responsible for the muscarinic enhancement of retrograde endocannabinoid signalling in the hippocampus. Eur J Neurosci (2003) 1.39