Published in Curr Biol on April 08, 2010
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The PAR-6 polarity protein regulates dendritic spine morphogenesis through p190 RhoGAP and the Rho GTPase. Dev Cell (2008) 1.77
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Distinct functions for Rho1 in maintaining adherens junctions and apical tension in remodeling epithelia. J Cell Biol (2009) 1.10
Cdc42 antagonizes Rho1 activity at adherens junctions to limit epithelial cell apical tension. J Cell Biol (2009) 0.99
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A distinctive role for focal adhesion proteins in three-dimensional cell motility. Nat Cell Biol (2010) 3.84
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The LIM protein AJUBA recruits protein arginine methyltransferase 5 to mediate SNAIL-dependent transcriptional repression. Mol Cell Biol (2008) 2.00
The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis. Nat Cell Biol (2013) 1.93
Loss of alpha-catenin decreases the strength of single E-cadherin bonds between human cancer cells. J Biol Chem (2009) 1.73
Ajuba LIM proteins are negative regulators of the Hippo signaling pathway. Curr Biol (2010) 1.73
The LIM protein Ajuba is recruited to cadherin-dependent cell junctions through an association with alpha-catenin. J Biol Chem (2002) 1.70
Ajuba LIM proteins are snail/slug corepressors required for neural crest development in Xenopus. Dev Cell (2008) 1.51
Temporal and spatial cooperation of Snail1 and Twist1 during epithelial-mesenchymal transition predicts for human breast cancer recurrence. Mol Cancer Res (2011) 1.42
The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration. J Cell Biol (2005) 1.33
{alpha}-Catenin mediates initial E-cadherin-dependent cell-cell recognition and subsequent bond strengthening. Proc Natl Acad Sci U S A (2008) 1.31
The Ajuba LIM domain protein is a corepressor for SNAG domain mediated repression and participates in nucleocytoplasmic Shuttling. Cancer Res (2007) 1.30
Dimensional and temporal controls of three-dimensional cell migration by zyxin and binding partners. Nat Commun (2012) 1.30
Actin cap associated focal adhesions and their distinct role in cellular mechanosensing. Sci Rep (2012) 1.29
The LIM protein Ajuba influences interleukin-1-induced NF-kappaB activation by affecting the assembly and activity of the protein kinase Czeta/p62/TRAF6 signaling complex. Mol Cell Biol (2005) 1.28
Lats2 kinase potentiates Snail1 activity by promoting nuclear retention upon phosphorylation. EMBO J (2011) 1.26
Phospholipase Cgamma2 modulates integrin signaling in the osteoclast by affecting the localization and activation of Src kinase. Mol Cell Biol (2008) 1.21
A multifunctional lentiviral-based gene knockdown with concurrent rescue that controls for off-target effects of RNAi. Genomics Proteomics Bioinformatics (2010) 1.20
Phosphatidylinositol 3-kinase activation is required to form the NKG2D immunological synapse. Mol Cell Biol (2007) 1.18
The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction. Sci Rep (2013) 1.13
Mechanisms of transcriptional regulation by Rb-E2F segregate by biological pathway. Oncogene (2003) 1.10
Distinct functions for Rho1 in maintaining adherens junctions and apical tension in remodeling epithelia. J Cell Biol (2009) 1.10
p38delta Mitogen-activated protein kinase is essential for skin tumor development in mice. Cancer Res (2009) 1.10
Ajuba functions as a histone deacetylase-dependent co-repressor for autoregulation of the growth factor-independent-1 transcription factor. J Biol Chem (2008) 1.10
Actin stress fiber pre-extension in human aortic endothelial cells. Cell Motil Cytoskeleton (2008) 1.08
Effect of focal adhesion proteins on endothelial cell adhesion, motility and orientation response to cyclic strain. Ann Biomed Eng (2009) 1.08
The LIM protein, Limd1, regulates AP-1 activation through an interaction with Traf6 to influence osteoclast development. J Biol Chem (2006) 1.07
The Arp2/3 complex mediates multigeneration dendritic protrusions for efficient 3-dimensional cancer cell migration. FASEB J (2013) 1.07
Mismatch in mechanical and adhesive properties induces pulsating cancer cell migration in epithelial monolayer. Biophys J (2012) 1.03
LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing. Proc Natl Acad Sci U S A (2010) 1.03
The LIM protein Ajuba regulates phosphatidylinositol 4,5-bisphosphate levels in migrating cells through an interaction with and activation of PIPKI alpha. Mol Cell Biol (2005) 1.01
Cdc42 antagonizes Rho1 activity at adherens junctions to limit epithelial cell apical tension. J Cell Biol (2009) 0.99
The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity. Nat Cell Biol (2012) 0.99
Differential regulation of apoptotic genes by Rb in human versus mouse cells. Oncogene (2004) 0.97
LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling. Proc Natl Acad Sci U S A (2010) 0.96
Endothelial cell migration on RGD-peptide-containing PEG hydrogels in the presence of sphingosine 1-phosphate. Biophys J (2007) 0.95
The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development. Proc Natl Acad Sci U S A (2008) 0.93
Differences in stability of repressor complexes at promoters underlie distinct roles for Rb family members. Oncogene (2004) 0.91
Nuclear ubiquitination by FBXL5 modulates Snail1 DNA binding and stability. Nucleic Acids Res (2013) 0.90
The amino terminus of the glial glutamate transporter GLT-1 interacts with the LIM protein Ajuba. Mol Cell Neurosci (2002) 0.89
CD46-induced immunomodulatory CD4+ T cells express the adhesion molecule and chemokine receptor pattern of intestinal T cells. J Immunol (2008) 0.89
Erythroid-stimulating agents in cancer therapy: potential dangers and biologic mechanisms. J Clin Oncol (2009) 0.87
α-actinin1 and 4 tyrosine phosphorylation is critical for stress fiber establishment, maintenance and focal adhesion maturation. Exp Cell Res (2013) 0.83
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The LIM protein LIMD1 influences osteoblast differentiation and function. Exp Cell Res (2008) 0.78
β-Catenin serves as a clutch between low and high intercellular E-cadherin bond strengths. Biophys J (2013) 0.77
Differential subcellular localisation of the tumour suppressor protein LIMD1 in breast cancer correlates with patient survival. Int J Cancer (2008) 0.77
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Context-dependent compensatory proliferation in epithelial homeostasis and tumorigenesis. Cell Cycle (2010) 0.75
Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Development (2016) 0.75