Published in World J Gastroenterol on April 21, 2010
Functional role of monocytes and macrophages for the inflammatory response in acute liver injury. Front Physiol (2012) 1.49
The role of chemokines in acute liver injury. Front Physiol (2012) 1.09
Functional role of chemokines in liver disease models. Nat Rev Gastroenterol Hepatol (2010) 1.06
Opposing effects of prednisolone treatment on T/NKT cell- and hepatotoxin-mediated hepatitis in mice. Hepatology (2014) 0.92
Circulating levels of the shed scavenger receptor sCD163 and association with outcome of critically ill patients. J Clin Immunol (2012) 0.89
Modulation of AP-endonuclease1 levels associated with hepatic cirrhosis in rat model treated with human umbilical cord blood mononuclear stem cells. Int J Clin Exp Pathol (2011) 0.84
Deficiency of interleukin-15 enhances susceptibility to acetaminophen-induced liver injury in mice. PLoS One (2012) 0.81
Two sides of one coin: massive hepatic necrosis and progenitor cell-mediated regeneration in acute liver failure. Front Physiol (2015) 0.80
Elevated soluble CD163 plasma levels are associated with disease severity in patients with hemorrhagic fever with renal syndrome. PLoS One (2014) 0.78
MRI of magnetically labeled mesenchymal stem cells in hepatic failure model. World J Gastroenterol (2010) 0.77
Immunomorphologic manifestations in mice liver infected with influenza A/H5N1, A/goose/Krasnoozerskoye/627/05 strain. Clin Dev Immunol (2013) 0.76
Acute organ failure following the loss of anti-apoptotic cellular FLICE-inhibitory protein involves activation of innate immune receptors. Cell Death Differ (2014) 0.75
Role of inflammation and infection in the pathogenesis of human acute liver failure: Clinical implications for monitoring and therapy. World J Gastroenterol (2016) 0.75
miRNA signatures can predict acute liver failure in hepatitis E infected pregnant females. Heliyon (2017) 0.75
The liver is a metabolic and immunologic organ: A reconsideration of metabolic decompensation due to infection in inborn errors of metabolism (IEM). Mol Genet Metab (2017) 0.75
Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat Immunol (2006) 11.06
The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor. J Exp Med (1994) 5.55
Monocyte deactivation in septic patients: restoration by IFN-gamma treatment. Nat Med (1997) 5.19
Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis. Hepatology (2009) 3.20
Patients with acute on chronic liver failure display "sepsis-like" immune paralysis. J Hepatol (2005) 2.66
Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models. Am J Pathol (1995) 2.55
The systemic inflammatory response syndrome in acute liver failure. Hepatology (2000) 2.47
Acute liver failure in the United States. Semin Liver Dis (2003) 2.39
T cell activation-associated hepatic injury: mediation by tumor necrosis factors and protection by interleukin 6. J Exp Med (1994) 2.31
Increased toxin-induced liver injury and fibrosis in interleukin-6-deficient mice. Hepatology (2000) 2.24
Suppression of concanavalin A-induced hepatitis in IFN-gamma(-/-) mice, but not in TNF-alpha(-/-) mice: role for IFN-gamma in activating apoptosis of hepatocytes. J Immunol (1997) 2.22
Concanavalin A-induced T-cell-mediated hepatic injury in mice: the role of tumor necrosis factor. Hepatology (1995) 2.21
Interleukin-10 expression and function in experimental murine liver inflammation and fibrosis. Hepatology (1998) 2.19
Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL. J Biol Chem (2001) 2.09
Monocyte HLA-DR antigen expression characterizes clinical outcome in the trauma patient. Br J Surg (1990) 2.05
Interleukin-10 controls neutrophilic infiltration, hepatocyte proliferation, and liver fibrosis induced by carbon tetrachloride in mice. Hepatology (1998) 2.04
Migration inhibitory factor expression in experimentally induced endotoxemia. Am J Pathol (1997) 2.00
Interleukin-6 protects liver against warm ischemia/reperfusion injury and promotes hepatocyte proliferation in the rodent. Hepatology (1997) 1.95
Identification and characterization of infiltrating macrophages in acetaminophen-induced liver injury. J Leukoc Biol (2008) 1.93
Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse. Hepatology (2002) 1.68
Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species. Hepatology (1999) 1.68
Protective role of Kupffer cells in acetaminophen-induced hepatic injury in mice. Chem Res Toxicol (2002) 1.68
Protection against acetaminophen-induced liver injury and lethality by interleukin 10: role of inducible nitric oxide synthase. Hepatology (2002) 1.67
An overview of animal models for investigating the pathogenesis and therapeutic strategies in acute hepatic failure. World J Gastroenterol (2009) 1.54
A pivotal involvement of IFN-gamma in the pathogenesis of acetaminophen-induced acute liver injury. FASEB J (2002) 1.51
Hepatoprotection via the IL-6/Stat3 pathway. J Clin Invest (2003) 1.51
The importance of immune dysfunction in determining outcome in acute liver failure. J Hepatol (2008) 1.50
Tumor necrosis factor alpha in the pathogenesis of human and murine fulminant hepatic failure. Gastroenterology (2000) 1.49
Dual role of CCR2 in the constitution and the resolution of liver fibrosis in mice. Am J Pathol (2009) 1.49
Tumor necrosis factor alpha, but not Fas, mediates hepatocellular apoptosis in the murine ischemic liver. Gastroenterology (2002) 1.42
Regulation of inflammatory monocyte/macrophage recruitment from the bone marrow during murine cytomegalovirus infection: role for type I interferons in localized induction of CCR2 ligands. J Immunol (2009) 1.40
Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen. Hepatology (1995) 1.36
Reduced monocyte HLA-DR expression: a novel biomarker of disease severity and outcome in acetaminophen-induced acute liver failure. Hepatology (2006) 1.30
Exaggerated hepatic injury due to acetaminophen challenge in mice lacking C-C chemokine receptor 2. Am J Pathol (2000) 1.30
Distinct patterns of chemokine expression are associated with leukocyte recruitment in alcoholic hepatitis and alcoholic cirrhosis. J Pathol (1998) 1.29
CCR2 mediates homeostatic and inflammatory release of Gr1(high) monocytes from the bone marrow, but is dispensable for bladder infiltration in bacterial urinary tract infection. J Immunol (2008) 1.28
Prospective study of bacterial infection in acute liver failure: an analysis of fifty patients. Hepatology (1990) 1.26
Critical involvement of interferon gamma in the pathogenesis of T-cell activation-associated hepatitis and regulatory mechanisms of interleukin-6 for the manifestations of hepatitis. Hepatology (1996) 1.25
Circulating proinflammatory cytokines (IL-1 beta, TNF-alpha, and IL-6) and IL-1 receptor antagonist (IL-1Ra) in fulminant hepatic failure and acute hepatitis. Clin Exp Immunol (1994) 1.25
Role of interleukin-6 in hepatic heat shock protein expression and protection against acetaminophen-induced liver disease. Biochem Biophys Res Commun (2003) 1.24
Characterization of the CCR2 chemokine receptor: functional CCR2 receptor expression in B cells. J Immunol (1997) 1.22
Role of IL-6 in an IL-10 and IL-4 double knockout mouse model uniquely susceptible to acetaminophen-induced liver injury. Chem Res Toxicol (2007) 1.21
Involvement of tumor necrosis factor-alpha in development of hepatic injury in galactosamine-sensitized mice. Hepatology (1990) 1.17
Hepatoprotective role of interleukin 10 in galactosamine/lipopolysaccharide mouse liver injury. Gastroenterology (1997) 1.14
IL-6 prevents T cell-mediated hepatitis via inhibition of NKT cells in CD4+ T cell- and STAT3-dependent manners. J Immunol (2004) 1.14
Cytokines and toxicity in acetaminophen overdose. J Clin Pharmacol (2005) 1.13
Soluble CD163 in patients with liver diseases: very high levels of soluble CD163 in patients with fulminant hepatic failure. J Gastroenterol (2005) 1.12
Soluble CD163 from activated macrophages predicts mortality in acute liver failure. J Hepatol (2007) 1.12
Early up-regulation of chemokine expression in fulminant hepatic failure. J Pathol (2003) 1.11
Production and role of interleukin-10 in concanavalin A-induced hepatitis in mice. Hepatology (1997) 1.11
Prevention of lethal acute hepatic failure by antimacrophage migration inhibitory factor antibody in mice treated with bacille Calmette-Guerin and lipopolysaccharide. Hepatology (1999) 1.10
Tumor necrosis factor-induced apoptosis during the poisoning of mice with hepatotoxins. Gastroenterology (1997) 1.05
Interleukin 6 and hepatocyte regeneration in acetaminophen toxicity in the mouse. Biochem Biophys Res Commun (2003) 1.03
C-C chemokine ligand 2/monocyte chemoattractant protein-1 directly inhibits NKT cell IL-4 production and is hepatoprotective in T cell-mediated hepatitis in the mouse. J Immunol (2003) 1.03
Interleukin 10 reduces lethality and hepatic injury induced by lipopolysaccharide in galactosamine-sensitized mice. Gastroenterology (1996) 1.03
Distinct roles of NF-kappaB p50 in the regulation of acetaminophen-induced inflammatory mediator production and hepatotoxicity. Toxicol Appl Pharmacol (2005) 1.01
Altered immune function of monocytes in different stages of patients with acute on chronic liver failure. Clin Exp Immunol (2007) 0.99
High levels of serum interleukin-10 and tumor necrosis factor-alpha are associated with fatality in fulminant hepatitis. J Infect Dis (2000) 0.96
Macrophage migration inhibitory factor in drug-induced liver injury: a role in susceptibility and stress responsiveness. Biochem Biophys Res Commun (2002) 0.92
Longitudinal monocyte human leukocyte antigen-DR expression is a prognostic marker in critically ill patients with decompensated liver cirrhosis. Liver Int (2008) 0.91
Pro-inflammatory cytokine release and mediation of the acute phase protein response in fulminant hepatic failure. Intensive Care Med (1998) 0.89
Reduction of liver tumor necrosis factor-alpha expression by targeting delivery of antisense oligonucleotides into Kupffer cells protects rats from fulminant hepatitis. J Gene Med (2009) 0.86
Macrophage migration inhibitory factor expression in male and female ethanol-fed rats. J Interferon Cytokine Res (2001) 0.85
Extent of the acute phase response in fulminant hepatic failure. Gut (1994) 0.83
Results from the International Conference of Experts on Intra-abdominal Hypertension and Abdominal Compartment Syndrome. I. Definitions. Intensive Care Med (2006) 7.26
Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis. Gastroenterology (2013) 5.88
Diagnosis and management of autoimmune hepatitis. Hepatology (2010) 5.27
Results from the International Conference of Experts on Intra-abdominal Hypertension and Abdominal Compartment Syndrome. II. Recommendations. Intensive Care Med (2007) 4.40
Acute liver failure. N Engl J Med (2013) 3.88
Blood lactate as an early predictor of outcome in paracetamol-induced acute liver failure: a cohort study. Lancet (2002) 3.73
Acute liver failure. Lancet (2010) 3.39
Evaluation of risk factors in the development of hepatocellular carcinoma in autoimmune hepatitis: Implications for follow-up and screening. Hepatology (2008) 2.98
Source and characterization of hepatic macrophages in acetaminophen-induced acute liver failure in humans. Hepatology (2012) 2.81
Arterial ammonia and clinical risk factors for encephalopathy and intracranial hypertension in acute liver failure. Hepatology (2007) 2.32
Hereditary fibrinogen A alpha-chain amyloidosis: phenotypic characterization of a systemic disease and the role of liver transplantation. Blood (2009) 2.30
Dysfunctional CD39(POS) regulatory T cells and aberrant control of T-helper type 17 cells in autoimmune hepatitis. Hepatology (2014) 2.29
Multigenerational epigenetic adaptation of the hepatic wound-healing response. Nat Med (2012) 2.28
Association of genetic variants of the chemokine receptor CCR5 and its ligands, RANTES and MCP-2, with outcome of HCV infection. Hepatology (2003) 2.23
Extracorporeal albumin dialysis with the molecular adsorbent recirculating system in acute-on-chronic liver failure: the RELIEF trial. Hepatology (2013) 2.08
Investigating mildly abnormal serum aminotransferase values. BMJ (2010) 2.07
Aerobic capacity during cardiopulmonary exercise testing and survival with and without liver transplantation for patients with chronic liver disease. Liver Transpl (2013) 2.05
Liver disease in pregnancy. Lancet (2010) 1.84
Lessons from look-back in acute liver failure? A single centre experience of 3300 patients. J Hepatol (2013) 1.83
Antibodies to conformational epitopes of soluble liver antigen define a severe form of autoimmune liver disease. Hepatology (2002) 1.77
Quantifying hepatic steatosis - more than meets the eye. Histopathology (2012) 1.76
Treatment of chronic hepatitis B virus infection in resource-constrained settings: expert panel consensus. Liver Int (2011) 1.75
Mucinous cystic neoplasms of the liver: a clinicopathological study and comparison with intraductal papillary neoplasms of the bile duct. Mod Pathol (2011) 1.74
The effect of hypertonic sodium chloride on intracranial pressure in patients with acute liver failure. Hepatology (2004) 1.71
Next-generation sequencing sheds light on the natural history of hepatitis C infection in patients who fail treatment. Hepatology (2014) 1.70
Functional study of CD4+CD25+ regulatory T cells in health and autoimmune hepatitis. J Immunol (2006) 1.70
Cardiac structure and function are altered in adults with non-alcoholic fatty liver disease. J Hepatol (2012) 1.70
Liver transplantation for HCV cirrhosis: improved survival in recent years and increased severity of recurrent disease in female recipients: results of a long term retrospective study. Liver Transpl (2007) 1.68
Cytochrome P450IID6-specific CD8 T cell immune responses mirror disease activity in autoimmune hepatitis type 2. Hepatology (2007) 1.68
Liver transplantation for acute liver failure in Europe: outcomes over 20 years from the ELTR database. J Hepatol (2012) 1.66
Beyond "cirrhosis": a proposal from the International Liver Pathology Study Group. Am J Clin Pathol (2012) 1.65
Does cross-reactivity between mycobacterium avium paratuberculosis and human intestinal antigens characterize Crohn's disease? Gastroenterology (2006) 1.64
ESPEN Guidelines on Parenteral Nutrition: hepatology. Clin Nutr (2009) 1.63
Serial circulating markers of inflammation in biliary atresia--evolution of the post-operative inflammatory process. Hepatology (2007) 1.61
Immunosuppression and donor age with respect to severity of HCV recurrence after liver transplantation. Liver Transpl (2005) 1.58
Impairment of CD4(+)CD25(+) regulatory T-cells in autoimmune liver disease. J Hepatol (2004) 1.54
Nitric oxide is an essential mediator of the protective effects of remote ischaemic preconditioning in a mouse model of liver ischaemia/reperfusion injury. Clin Sci (Lond) (2011) 1.54
Prevalence of the activating JAK2 tyrosine kinase mutation V617F in the Budd-Chiari syndrome. Gastroenterology (2006) 1.51
Autoantigen-specific regulatory T cells, a potential tool for immune-tolerance reconstitution in type-2 autoimmune hepatitis. Hepatology (2010) 1.51
Biliary intraepithelial neoplasia: an international interobserver agreement study and proposal for diagnostic criteria. Mod Pathol (2007) 1.51
Character and temporal evolution of apoptosis in acetaminophen-induced acute liver failure*. Crit Care Med (2013) 1.51
Evidence of rebalanced coagulation in acute liver injury and acute liver failure as measured by thrombin generation. Liver Int (2013) 1.50
The importance of immune dysfunction in determining outcome in acute liver failure. J Hepatol (2008) 1.50
Distinct microRNA profiles are associated with the severity of hepatitis C virus recurrence and acute cellular rejection after liver transplantation. Liver Transpl (2013) 1.48
Alcohol dehydrogenase-specific T-cell responses are associated with alcohol consumption in patients with alcohol-related cirrhosis. Hepatology (2013) 1.47
Phenotyping murine models of non-alcoholic fatty liver disease through metabolic profiling of intact liver tissue. Clin Sci (Lond) (2009) 1.47
Liver transplantation in human immunodeficiency virus-infected patients: procoagulant, but is antithrombotic prophylaxis required? Liver Transpl (2012) 1.45
Efficacy of loco-regional ablation therapy of HCC in a population of liver transplanted patients. Dig Dis Sci (2007) 1.41
Immunohistochemical phenotyping of the inflammatory infiltrate in de novo autoimmune hepatitis after liver transplantation in children. Pediatr Transplant (2012) 1.38
BCSH/BSBMT guideline: diagnosis and management of veno-occlusive disease (sinusoidal obstruction syndrome) following haematopoietic stem cell transplantation. Br J Haematol (2013) 1.38
Acute sickle cell hepatopathy represents a potential contraindication for percutaneous liver biopsy. Blood (2002) 1.34
Autoimmune liver serology: current diagnostic and clinical challenges. World J Gastroenterol (2008) 1.34
A systematic review of the quality of liver biopsy specimens. Am J Clin Pathol (2006) 1.34
Reduced monocyte HLA-DR expression: a novel biomarker of disease severity and outcome in acetaminophen-induced acute liver failure. Hepatology (2006) 1.30
X-inactivation patch size in human female tissue confounds the assessment of tumor clonality. Proc Natl Acad Sci U S A (2003) 1.30
Antibodies against homologous microbial caseinolytic proteases P characterise primary biliary cirrhosis. J Hepatol (2002) 1.24
The clinical importance of adrenal insufficiency in acute hepatic dysfunction. Hepatology (2002) 1.19
Genetic predisposition in NAFLD and NASH: impact on severity of liver disease and response to treatment. Curr Pharm Des (2013) 1.16
Autoimmune hepatitis: a comprehensive review. J Autoimmun (2012) 1.16
The significance of autoantibodies and immunoglobulins in acute liver failure: a cohort study. J Hepatol (2007) 1.16
The increasing prevalence of hepatitis delta virus (HDV) infection in South London. J Med Virol (2008) 1.15
Autoimmune hepatitis. Nat Rev Gastroenterol Hepatol (2011) 1.14
PBC screen: an IgG/IgA dual isotype ELISA detecting multiple mitochondrial and nuclear autoantibodies specific for primary biliary cirrhosis. J Autoimmun (2010) 1.13
Serum levels of CK18 M30 and leptin are useful predictors of steatohepatitis and fibrosis in paediatric NAFLD. J Pediatr Gastroenterol Nutr (2010) 1.13
Effect of CD4+ CD25+ regulatory T-cells on CD8 T-cell function in patients with autoimmune hepatitis. J Autoimmun (2005) 1.13
The histopathology of regeneration in massive hepatic necrosis. Semin Liver Dis (2004) 1.12
A multifaceted imbalance of T cells with regulatory function characterizes type 1 autoimmune hepatitis. Hepatology (2010) 1.10
The SOD2 C47T polymorphism influences NAFLD fibrosis severity: evidence from case-control and intra-familial allele association studies. J Hepatol (2011) 1.09
Autoimmune hepatitis. J Pediatr Gastroenterol Nutr (2009) 1.09
The impaired immune regulation of autoimmune hepatitis is linked to a defective galectin-9/tim-3 pathway. Hepatology (2012) 1.09
Review of the neurological manifestations of hepatitis E infection. Ann Hepatol (2012) 1.08
Reply: To PMID 22334567. Hepatology (2013) 1.08
Liver transplantation in children. J Hepatol (2006) 1.06
Microbial mimics are major targets of crossreactivity with human pyruvate dehydrogenase in primary biliary cirrhosis. J Hepatol (2004) 1.06
Pulmonary artery catheter versus pulse contour analysis: a prospective epidemiological study. Crit Care (2006) 1.05
Biliary atresia. Semin Immunopathol (2009) 1.05
Molecular characterization of hepatocellular adenomas developed in patients with glycogen storage disease type I. J Hepatol (2012) 1.05
Aetiopathogenesis of autoimmune hepatitis. J Autoimmun (2009) 1.04
Primary biliary cirrhosis is characterized by IgG3 antibodies cross-reactive with the major mitochondrial autoepitope and its Lactobacillus mimic. Hepatology (2005) 1.03
Intensive care management of acute liver failure. Semin Liver Dis (2008) 1.03
Polyclonal T-cell responses to cytochrome P450IID6 are associated with disease activity in autoimmune hepatitis type 2. Gastroenterology (2006) 1.03
Renal dysfunction in chronic liver disease. Crit Care (2010) 1.03
A polymorphism in IL28B distinguishes exposed, uninfected individuals from spontaneous resolvers of HCV infection. Gastroenterology (2011) 1.03
Autoantibodies and their antigens in autoimmune hepatitis. Semin Liver Dis (2009) 1.02
Treatment challenges and investigational opportunities in autoimmune hepatitis. Hepatology (2005) 1.02
Mixed phenotype hepatocellular carcinoma after transarterial chemoembolization and liver transplantation. Liver Transpl (2011) 1.01
Liver transplantation in adults with acute liver failure. J Hepatol (2004) 1.00
Chronic hepatitis B virus infection in the Asia-Pacific region and Africa: review of disease progression. J Gastroenterol Hepatol (2005) 1.00
Proteomic analysis of extracellular matrix from the hepatic stellate cell line LX-2 identifies CYR61 and Wnt-5a as novel constituents of fibrotic liver. J Proteome Res (2012) 1.00
Outcome after wait-listing for emergency liver transplantation in acute liver failure: a single centre experience. J Hepatol (2008) 1.00
New ELISA for detecting primary biliary cirrhosis-specific antimitochondrial antibodies. Clin Chem (2009) 0.99