Published in Biol Direct on April 20, 2010
Systemic buffers inhibit carcinogenesis in TRAMP mice. J Urol (2012) 1.28
Acidic tumor microenvironment and pH-sensing G protein-coupled receptors. Front Physiol (2013) 1.10
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Cancer models, genomic instability and somatic cellular Darwinian evolution. Biol Direct (2010) 0.90
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Roles for hypoxia-regulated genes during cervical carcinogenesis: somatic evolution during the hypoxia-glycolysis-acidosis sequence. Gynecol Oncol (2007) 1.13
Effects of short-term training on plasma acid-base balance during incremental exercise in man. J Physiol (2003) 1.12
Lifetime physical activity and the risk of breast cancer: a case-control study. Cancer Detect Prev (2007) 0.94
Effect of physical activity on breast cancer risk: findings of the Japan collaborative cohort study. Cancer Epidemiol Biomarkers Prev (2008) 0.91
Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration. Nature (2008) 4.67
Causes and consequences of increased glucose metabolism of cancers. J Nucl Med (2008) 3.79
Environment-mediated drug resistance: a major contributor to minimal residual disease. Nat Rev Cancer (2009) 3.49
Bicarbonate increases tumor pH and inhibits spontaneous metastases. Cancer Res (2009) 3.40
Conformational spread as a mechanism for cooperativity in the bacterial flagellar switch. Science (2010) 3.08
Evolutionary dynamics of carcinogenesis and why targeted therapy does not work. Nat Rev Cancer (2012) 2.71
pH imaging. A review of pH measurement methods and applications in cancers. IEEE Eng Med Biol Mag (2004) 2.68
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Acidity generated by the tumor microenvironment drives local invasion. Cancer Res (2013) 2.63
Inherent noise can facilitate coherence in collective swarm motion. Proc Natl Acad Sci U S A (2009) 2.19
Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer. Proc Natl Acad Sci U S A (2007) 1.99
Self-organizing and stochastic behaviors during the regeneration of hair stem cells. Science (2011) 1.96
The potential role of systemic buffers in reducing intratumoral extracellular pH and acid-mediated invasion. Cancer Res (2009) 1.92
Adaptive landscapes and emergent phenotypes: why do cancers have high glycolysis? J Bioenerg Biomembr (2007) 1.83
Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression. Semin Cancer Biol (2008) 1.76
A theoretical quantitative model for evolution of cancer chemotherapy resistance. Biol Direct (2010) 1.69
Hypoxia and adaptive landscapes in the evolution of carcinogenesis. Cancer Metastasis Rev (2007) 1.68
Mathematical oncology: cancer summed up. Nature (2003) 1.67
A PHABULOSA/cytokinin feedback loop controls root growth in Arabidopsis. Curr Biol (2012) 1.61
Beyond mammography: new frontiers in breast cancer screening. Am J Med (2013) 1.61
Metabolic changes during carcinogenesis: potential impact on invasiveness. J Theor Biol (2006) 1.59
Angiogenesis and vascular remodelling in normal and cancerous tissues. J Math Biol (2008) 1.55
Prediction of drug response in breast cancer using integrative experimental/computational modeling. Cancer Res (2009) 1.53
Acid treatment of melanoma cells selects for invasive phenotypes. Clin Exp Metastasis (2008) 1.44
Sweat but no gain: inhibiting proliferation of multidrug resistant cancer cells with "ersatzdroges". Int J Cancer (2014) 1.44
Automated Delineation of Lung Tumors from CT Images Using a Single Click Ensemble Segmentation Approach. Pattern Recognit (2013) 1.36
Multiscale modelling of vascular tumour growth in 3D: the roles of domain size and boundary conditions. PLoS One (2011) 1.36
A physical sciences network characterization of non-tumorigenic and metastatic cells. Sci Rep (2013) 1.33
An analysis of B cell selection mechanisms in germinal centers. Math Med Biol (2006) 1.32
Systemic buffers inhibit carcinogenesis in TRAMP mice. J Urol (2012) 1.28
The role of acidity in solid tumour growth and invasion. J Theor Biol (2005) 1.23
Regulation of the Warburg effect in early-passage breast cancer cells. Neoplasia (2008) 1.23
Exploiting evolution to treat drug resistance: combination therapy and the double bind. Mol Pharm (2012) 1.22
Reduction of metastasis using a non-volatile buffer. Clin Exp Metastasis (2011) 1.21
Interactions between Shh, Sostdc1 and Wnt signaling and a new feedback loop for spatial patterning of the teeth. Development (2011) 1.21
Variance of SUVs for FDG-PET/CT is greater in clinical practice than under ideal study settings. Clin Nucl Med (2013) 1.19
Evolutionary approaches to prolong progression-free survival in breast cancer. Cancer Res (2012) 1.19
Life history trade-offs in cancer evolution. Nat Rev Cancer (2013) 1.16
Proton dynamics in cancer. J Transl Med (2010) 1.14
Mixed-mode pattern in Doublefoot mutant mouse limb--Turing reaction-diffusion model on a growing domain during limb development. J Theor Biol (2005) 1.12
Examples of mathematical modeling: tales from the crypt. Cell Cycle (2007) 1.11
A theoretical investigation of the effect of proliferation and adhesion on monoclonal conversion in the colonic crypt. J Theor Biol (2012) 1.07
Multiscale mechanisms of cell migration during development: theory and experiment. Development (2012) 1.07
A model invalidation-based approach for elucidating biological signalling pathways, applied to the chemotaxis pathway in R. sphaeroides. BMC Syst Biol (2009) 1.04
Spots and stripes: pleomorphic patterning of stem cells via p-ERK-dependent cell chemotaxis shown by feather morphogenesis and mathematical simulation. Dev Biol (2009) 1.03
Evolutionary dynamics in cancer therapy. Mol Pharm (2011) 1.03
Multi-cellular rosettes in the mouse visceral endoderm facilitate the ordered migration of anterior visceral endoderm cells. PLoS Biol (2012) 1.02
Directional persistence and the optimality of run-and-tumble chemotaxis. Comput Biol Chem (2009) 0.99
Speed of pattern appearance in reaction-diffusion models: implications in the pattern formation of limb bud mesenchyme cells. Bull Math Biol (2004) 0.99
Non-linear incidence and stability of infectious disease models. Math Med Biol (2005) 0.98
Minimization of thermodynamic costs in cancer cell invasion. Proc Natl Acad Sci U S A (2013) 0.98
Test-retest reproducibility analysis of lung CT image features. J Digit Imaging (2014) 0.98
On the proportion of cancer stem cells in a tumour. J Theor Biol (2010) 0.97
STOCHSIMGPU: parallel stochastic simulation for the Systems Biology Toolbox 2 for MATLAB. Bioinformatics (2011) 0.97
A mathematical model of tumour and blood pHe regulation: The HCO3-/CO2 buffering system. Math Biosci (2010) 0.97
Molecular and functional imaging of breast cancer. Cancer Control (2010) 0.96
Information dynamics in living systems: prokaryotes, eukaryotes, and cancer. PLoS One (2011) 0.95
Reptile scale paradigm: Evo-Devo, pattern formation and regeneration. Int J Dev Biol (2009) 0.95
Order in a multidimensional system. Phys Rev E Stat Nonlin Soft Matter Phys (2011) 0.95
Free Base Lysine Increases Survival and Reduces Metastasis in Prostate Cancer Model. J Cancer Sci Ther (2011) 0.94
Tumour-stromal interactions in acid-mediated invasion: a mathematical model. J Theor Biol (2010) 0.94
Modeling chemotaxis reveals the role of reversed phosphotransfer and a bi-functional kinase-phosphatase. PLoS Comput Biol (2010) 0.94
A quantitative theoretical model for the development of malignancy in ductal carcinoma in situ. J Theor Biol (2009) 0.94
Systems model of T cell receptor proximal signaling reveals emergent ultrasensitivity. PLoS Comput Biol (2013) 0.94
Age-related changes in speed and mechanism of adult skeletal muscle stem cell migration. Stem Cells (2012) 0.93
Interpreting two-photon imaging data of lymphocyte motility. Phys Rev E Stat Nonlin Soft Matter Phys (2005) 0.93
From segment to somite: segmentation to epithelialization analyzed within quantitative frameworks. Dev Dyn (2007) 0.92
Growth-induced mass flows in fungal networks. Proc Biol Sci (2010) 0.92
Systems biologists seek fuller integration of systems biology approaches in new cancer research programs. Cancer Res (2009) 0.92
Mode transitions in a model reaction-diffusion system driven by domain growth and noise. Bull Math Biol (2006) 0.91
Distinct mechanisms underlie pattern formation in the skin and skin appendages. Birth Defects Res C Embryo Today (2006) 0.91
A numerical approach to the study of spatial pattern formation in the ligaments of arcoid bivalves. Bull Math Biol (2002) 0.90
Collagen bundle morphometry in skin and scar tissue: a novel distance mapping method provides superior measurements compared to Fourier analysis. J Microsc (2011) 0.90
Waves and patterning in developmental biology: vertebrate segmentation and feather bud formation as case studies. Int J Dev Biol (2009) 0.90
Novel methods for analysing bacterial tracks reveal persistence in Rhodobacter sphaeroides. PLoS Comput Biol (2013) 0.90
A fibrocontractive mechanochemical model of dermal wound closure incorporating realistic growth factor kinetics. Bull Math Biol (2012) 0.90
Modelling spatially regulated beta-catenin dynamics and invasion in intestinal crypts. Biophys J (2010) 0.89
Implementing vertex dynamics models of cell populations in biology within a consistent computational framework. Prog Biophys Mol Biol (2013) 0.89
Evolutionary ecology of human papillomavirus: trade-offs, coexistence, and origins of high-risk and low-risk types. J Infect Dis (2011) 0.89
Mathematical models for somite formation. Curr Top Dev Biol (2008) 0.89
Stochastic reaction and diffusion on growing domains: understanding the breakdown of robust pattern formation. Phys Rev E Stat Nonlin Soft Matter Phys (2011) 0.89
Modeling the skin pattern of fishes. Phys Rev E Stat Nonlin Soft Matter Phys (2009) 0.89
Evolution of tumor invasiveness: the adaptive tumor microenvironment landscape model. Cancer Res (2011) 0.89
Models for pattern formation in somitogenesis: a marriage of cellular and molecular biology. C R Biol (2002) 0.88
Optimization of synchronization in complex clustered networks. Chaos (2008) 0.88
Conformational spread in the flagellar motor switch: a model study. PLoS Comput Biol (2012) 0.88
Mathematical modelling of tumour acidity. J Theor Biol (2008) 0.88
A lyapunov function and global properties for sir and seir epidemiological models with nonlinear incidence. Math Biosci Eng (2004) 0.88
From a discrete to a continuum model of cell dynamics in one dimension. Phys Rev E Stat Nonlin Soft Matter Phys (2009) 0.87
Stability analysis of non-autonomous reaction-diffusion systems: the effects of growing domains. J Math Biol (2009) 0.87
Feedback control architecture and the bacterial chemotaxis network. PLoS Comput Biol (2011) 0.87
Natural resistance to cancers: a Darwinian hypothesis to explain Peto's paradox. BMC Cancer (2012) 0.87
Vascular measurements correlate with estrogen receptor status. BMC Cancer (2014) 0.87
Cutting edge: back to "one-way" germinal centers. J Immunol (2005) 0.86