Published in Nat Rev Mol Cell Biol on May 12, 2010
Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart size. Sci Signal (2011) 2.38
Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-κB. Nat Med (2014) 2.30
GSK-3: Functional Insights from Cell Biology and Animal Models. Front Mol Neurosci (2011) 1.99
Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis. Cell Stem Cell (2013) 1.41
Key signaling nodes in mammary gland development and cancer: β-catenin. Breast Cancer Res (2010) 1.24
Signal integration in TGF-β, WNT, and Hippo pathways. F1000Prime Rep (2013) 1.15
Glycogen synthase kinase 3 beta (GSK3β) phosphorylates the RNAase III enzyme Drosha at S300 and S302. PLoS One (2011) 1.09
WW domain interactions regulate the Hippo tumor suppressor pathway. Cell Death Dis (2011) 1.09
Does GSK-3 provide a shortcut for PI3K activation of Wnt signalling? F1000 Biol Rep (2010) 1.07
NANOG induction of fetal liver kinase-1 (FLK1) transcription regulates endothelial cell proliferation and angiogenesis. Blood (2010) 1.04
Mutations in Frizzled 6 cause isolated autosomal-recessive nail dysplasia. Am J Hum Genet (2011) 1.00
Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3. Synapse (2011) 0.99
Wnt4 enhances murine hematopoietic progenitor cell expansion through a planar cell polarity-like pathway. PLoS One (2011) 0.98
Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration. PLoS One (2013) 0.92
Dimerization and cytoplasmic localization regulate Hippo kinase signaling activity in organ size control. J Biol Chem (2012) 0.89
Combinatorial cell-specific regulation of GSK3 directs cell differentiation and polarity in Dictyostelium. Development (2011) 0.89
WNT-5A: signaling and functions in health and disease. Cell Mol Life Sci (2015) 0.86
Gpr177 deficiency impairs mammary development and prohibits Wnt-induced tumorigenesis. PLoS One (2013) 0.82
Cell polarity: The missing link in skeletal morphogenesis? Organogenesis (2011) 0.82
Analysis of PRICKLE1 in human cleft palate and mouse development demonstrates rare and common variants involved in human malformations. Mol Genet Genomic Med (2013) 0.82
Erect Wing facilitates context-dependent Wnt/Wingless signaling by recruiting the cell-specific Armadillo-TCF adaptor Earthbound to chromatin. Development (2011) 0.81
Major remodelling of the murine stem cell kinome following differentiation in the hematopoietic compartment. J Proteome Res (2011) 0.81
Glycogen synthase kinase-3 levels and phosphorylation undergo large fluctuations in mouse brain during development. Bipolar Disord (2012) 0.81
Can a two-faced kinase be exploited for osteosarcoma? J Natl Cancer Inst (2012) 0.80
Where gene discovery turns into systems biology: genome-scale RNAi screens in Drosophila. Wiley Interdiscip Rev Syst Biol Med (2010) 0.79
Global regulation of a differentiation MAPK pathway in yeast. Genetics (2014) 0.79
14-3-3σ controls corneal epithelium homeostasis and wound healing. Invest Ophthalmol Vis Sci (2011) 0.79
Signals controlling un-differentiated states in embryonic stem and cancer cells: role of the phosphatidylinositol 3' kinase pathway. J Cell Physiol (2014) 0.78
Prickle1 stunts limb growth through alteration of cell polarity and gene expression. Dev Dyn (2013) 0.78
The Anti-Tumor Activity of Succinyl Macrolactin A Is Mediated through the β-Catenin Destruction Complex via the Suppression of Tankyrase and PI3K/Akt. PLoS One (2015) 0.77
The use of small molecule probes to study spatially separated stimulus-induced signaling pathways. Bioorg Med Chem Lett (2012) 0.77
Elucidating the sources of β-catenin dynamics in human neural progenitor cells. PLoS One (2012) 0.76
High basal Wnt signaling is further induced by PI3K/mTor inhibition but sensitive to cSRC inhibition in mammary carcinoma cell lines with HER2/3 overexpression. BMC Cancer (2015) 0.76
Cell signalling: Regulation and crosstalk. Nat Rev Mol Cell Biol (2010) 0.75
Gsk3 is a metabolic checkpoint regulator in B cells. Nat Immunol (2017) 0.75
Structural and Functional Characterization of a Caenorhabditis elegans Genetic Interaction Network within Pathways. PLoS Comput Biol (2016) 0.75
Transcriptome analysis of mammary epithelial cell gene expression reveals novel roles of the extracellular matrix. Biochem Biophys Rep (2017) 0.75
Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell (2009) 18.31
Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol Cell Biol (2002) 10.95
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature (2009) 9.15
The renaissance of GSK3. Nat Rev Mol Cell Biol (2001) 7.99
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene. Cancer Cell (2009) 7.39
Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. PLoS Biol (2006) 7.36
The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis. Nat Cell Biol (2005) 6.74
Proximal events in Wnt signal transduction. Nat Rev Mol Cell Biol (2009) 6.66
The many ways of Wnt in cancer. Curr Opin Genet Dev (2007) 6.29
Towards an integrated view of Wnt signaling in development. Development (2009) 6.07
The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway. Dev Cell (2008) 5.58
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation. Nature (2005) 5.50
The role of protein phosphorylation in neural and hormonal control of cellular activity. Nature (1982) 5.30
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling. Science (2007) 5.08
Delineation of a Fat tumor suppressor pathway. Nat Genet (2006) 5.06
The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control. Dev Cell (2008) 4.90
The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway. PLoS Biol (2003) 4.89
Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction. Nature (2005) 4.88
Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis. EMBO J (2005) 4.82
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways. Cell (2009) 4.81
Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases. Oncogene (2007) 4.80
The Hippo pathway regulates Wnt/beta-catenin signaling. Dev Cell (2010) 4.49
Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines. Dev Cell (2007) 4.39
Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease. Nat Genet (2008) 4.28
The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway. Genes Cells (2003) 4.11
The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals. Cancer Cell (2008) 4.08
The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF. Nature (1999) 4.01
The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size. Curr Biol (2006) 3.90
Quantitative analysis of pathways controlling extrinsic apoptosis in single cells. Mol Cell (2008) 3.88
The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway. Curr Biol (2006) 3.83
Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway. Curr Biol (2006) 3.72
Beta-catenin hits chromatin: regulation of Wnt target gene activation. Nat Rev Mol Cell Biol (2009) 3.67
The Hippo-YAP pathway: new connections between regulation of organ size and cancer. Curr Opin Cell Biol (2008) 3.63
Planar cell polarity signaling: from fly development to human disease. Annu Rev Genet (2008) 3.43
SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila. Curr Biol (2008) 3.39
The incoherent feedforward loop can provide fold-change detection in gene regulation. Mol Cell (2009) 3.38
Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. Development (2007) 3.28
YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway. Nat Cell Biol (2009) 3.26
Regulation of Frizzled by fat-like cadherins during planar polarity signaling in the Drosophila compound eye. Cell (2002) 3.25
Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development. J Cell Biol (1996) 3.01
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded. Dev Cell (2010) 2.96
A member of the Frizzled protein family mediating axis induction by Wnt-5A. Science (1997) 2.90
Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex. Dev Cell (2008) 2.89
Morphogen control of wing growth through the Fat signaling pathway. Dev Cell (2008) 2.80
Kibra is a regulator of the Salvador/Warts/Hippo signaling network. Dev Cell (2010) 2.73
Interactions between Fat and Dachsous and the regulation of planar cell polarity in the Drosophila wing. Development (2004) 2.66
YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation. Genes Dev (2009) 2.58
The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie. Dev Cell (2009) 2.53
Two separate molecular systems, Dachsous/Fat and Starry night/Frizzled, act independently to confer planar cell polarity. Development (2006) 2.50
Asymmetric homotypic interactions of the atypical cadherin flamingo mediate intercellular polarity signaling. Cell (2008) 2.37
Differential transformation of mammary epithelial cells by Wnt genes. Mol Cell Biol (1994) 2.37
The WW domain protein Kibra acts upstream of Hippo in Drosophila. Dev Cell (2010) 2.34
MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans. Nature (1999) 2.32
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd. Proc Natl Acad Sci U S A (2001) 2.22
Identification of distinct classes and functional domains of Wnts through expression of wild-type and chimeric proteins in Xenopus embryos. Mol Cell Biol (1995) 2.21
Naked cuticle targets dishevelled to antagonize Wnt signal transduction. Genes Dev (2001) 2.16
Evidence that fold-change, and not absolute level, of beta-catenin dictates Wnt signaling. Mol Cell (2009) 2.11
GSK-3 is a master regulator of neural progenitor homeostasis. Nat Neurosci (2009) 2.11
An in vivo structure-function study of armadillo, the beta-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signaling. J Cell Biol (1996) 2.09
Planar cell polarity in the Drosophila eye is directed by graded Four-jointed and Dachsous expression. Development (2004) 2.03
Wnt5a regulates distinct signalling pathways by binding to Frizzled2. EMBO J (2009) 1.97
Transcription factor choice in the Hippo signaling pathway: homothorax and yorkie regulation of the microRNA bantam in the progenitor domain of the Drosophila eye imaginal disc. Genes Dev (2009) 1.84
Developmental compartments and planar polarity in Drosophila. Curr Biol (2002) 1.83
Ror receptor tyrosine kinases: orphans no more. Trends Cell Biol (2008) 1.82
RORalpha attenuates Wnt/beta-catenin signaling by PKCalpha-dependent phosphorylation in colon cancer. Mol Cell (2010) 1.78
Salvador-warts-hippo signaling promotes Drosophila posterior follicle cell maturation downstream of notch. Curr Biol (2007) 1.75
The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma. Oncogene (2009) 1.75
Phosphorylation of the tumor suppressor fat is regulated by its ligand Dachsous and the kinase discs overgrown. Curr Biol (2009) 1.74
The tumor-suppressor and cell adhesion molecule Fat controls planar polarity via physical interactions with Atrophin, a transcriptional co-repressor. Development (2003) 1.69
Processing and phosphorylation of the Fat receptor. Proc Natl Acad Sci U S A (2009) 1.66
The salvador-warts-hippo pathway is required for epithelial proliferation and axis specification in Drosophila. Curr Biol (2007) 1.59
Ror-family receptor tyrosine kinases in noncanonical Wnt signaling: their implications in developmental morphogenesis and human diseases. Dev Dyn (2010) 1.58
Phosphatidylinositol 3-kinase signaling does not activate the wnt cascade. J Biol Chem (2009) 1.57
Towards a model of the organisation of planar polarity and pattern in the Drosophila abdomen. Development (2002) 1.55
Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling. Dev Biol (2009) 1.54
The hippo pathway promotes Notch signaling in regulation of cell differentiation, proliferation, and oocyte polarity. PLoS One (2008) 1.53
Signaling by wingless in Drosophila. Dev Biol (1994) 1.53
Dual positive and negative regulation of wingless signaling by adenomatous polyposis coli. Science (2008) 1.44
The skinny on Fat: an enormous cadherin that regulates cell adhesion, tissue growth, and planar cell polarity. Curr Opin Cell Biol (2009) 1.41
The adenomatous polyposis coli protein is an essential regulator of radial glial polarity and construction of the cerebral cortex. Neuron (2009) 1.39
The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc. EMBO J (2009) 1.33
The cadherins fat and dachsous regulate dorsal/ventral signaling in the Drosophila eye. Curr Biol (2002) 1.29
WNT5A, a putative tumour suppressor of lymphoid malignancies, is inactivated by aberrant methylation in acute lymphoblastic leukaemia. Eur J Cancer (2007) 1.20
Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo. PLoS Genet (2010) 1.16
Convergence and extension movements during vertebrate gastrulation. Curr Top Dev Biol (2009) 1.14
Retracted Phosphoinositide 3-kinase/Akt inhibits MST1-mediated pro-apoptotic signaling through phosphorylation of threonine 120. J Biol Chem (2009) 1.12
Original CIN: reviewing roles for APC in chromosome instability. J Cell Biol (2008) 1.10
Binding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cells. EMBO J (2010) 1.10
The tumor suppressor genes dachsous and fat modulate different signalling pathways by regulating dally and dally-like. Proc Natl Acad Sci U S A (2008) 1.08
Adenomatous polyposis coli is present near the minimal level required for accurate graded responses to the Wingless morphogen. Development (2008) 0.99
Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway. Mol Syst Biol (2009) 0.94
Signalling molecules, growth regulators and cell cycle control in Drosophila. Cell Cycle (2008) 0.91
Wnt signaling: Ig-norrin the dogma. Curr Biol (2004) 0.88
GSK-3: tricks of the trade for a multi-tasking kinase. J Cell Sci (2003) 10.89
Systematic discovery of in vivo phosphorylation networks. Cell (2007) 6.94
Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines. Dev Cell (2007) 4.39
Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. Proc Natl Acad Sci U S A (2004) 3.60
Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. Curr Biol (2004) 3.45
Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium. J Neurosci (2004) 3.12
IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins. Immunity (2006) 2.58
Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B. Mol Cell Biol (2002) 2.56
Essential roles for GSK-3s and GSK-3-primed substrates in neurotrophin-induced and hippocampal axon growth. Neuron (2006) 2.23
Unravelling the activation mechanisms of protein kinase B/Akt. FEBS Lett (2003) 2.22
Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism. Cell Metab (2007) 2.12
GSK-3 is a master regulator of neural progenitor homeostasis. Nat Neurosci (2009) 2.11
Tissue-specific role of glycogen synthase kinase 3beta in glucose homeostasis and insulin action. Mol Cell Biol (2008) 2.03
Convergence of multiple signaling cascades at glycogen synthase kinase 3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway. Mol Cell Biol (2002) 1.91
CpG Island microarray probe sequences derived from a physical library are representative of CpG Islands annotated on the human genome. Nucleic Acids Res (2005) 1.89
Glycogen synthase kinase-3--an overview of an over-achieving protein kinase. Curr Drug Targets (2006) 1.88
Functional distinctions of protein kinase B/Akt isoforms defined by their influence on cell migration. Trends Cell Biol (2006) 1.86
Role of glycogen synthase kinase-3 in cell fate and epithelial-mesenchymal transitions. Cells Tissues Organs (2007) 1.77
Deletion of GSK-3beta in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation. J Clin Invest (2008) 1.76
A molecular compendium of genes expressed in multiple myeloma. Blood (2002) 1.70
DREAM is a critical transcriptional repressor for pain modulation. Cell (2002) 1.63
Role of glycogen synthase kinase-3 in cancer: regulation by Wnts and other signaling pathways. Adv Cancer Res (2002) 1.62
Role of phosphoinositide 3-kinase {alpha}, protein kinase C, and L-type Ca2+ channels in mediating the complex actions of angiotensin II on mouse cardiac contractility. Hypertension (2010) 1.59
IL-17 receptor signaling inhibits C/EBPbeta by sequential phosphorylation of the regulatory 2 domain. Sci Signal (2009) 1.57
Akt1 and akt2 play distinct roles in the initiation and metastatic phases of mammary tumor progression. Cancer Res (2009) 1.53
Unique and overlapping functions of GSK-3 isoforms in cell differentiation and proliferation and cardiovascular development. J Biol Chem (2008) 1.49
Problems with co-funding in Canada. Science (2005) 1.48
Retracted GSK-3beta in mouse fibroblasts controls wound healing and fibrosis through an endothelin-1-dependent mechanism. J Clin Invest (2008) 1.46
Abnormalities in brain structure and behavior in GSK-3alpha mutant mice. Mol Brain (2009) 1.44
Negative regulation of mixed lineage kinase 3 by protein kinase B/AKT leads to cell survival. J Biol Chem (2002) 1.43
Serum and glucocorticoid-regulated protein kinases: variations on a theme. J Cell Biochem (2006) 1.42
Genetic deficiency of glycogen synthase kinase-3beta corrects diabetes in mouse models of insulin resistance. PLoS Biol (2008) 1.40
Glycogen synthase kinase-3beta induces neuronal cell death via direct phosphorylation of mixed lineage kinase 3. J Biol Chem (2007) 1.37
Glycogen synthase kinase-3beta regulates post-myocardial infarction remodeling and stress-induced cardiomyocyte proliferation in vivo. Circ Res (2010) 1.33
GSK-3beta controls osteogenesis through regulating Runx2 activity. PLoS One (2007) 1.29
CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly. J Exp Med (2002) 1.22
CD4+ and CD8+ T cell survival is regulated differentially by protein kinase Ctheta, c-Rel, and protein kinase B. J Immunol (2007) 1.18
The active form of glycogen synthase kinase-3beta is associated with granulovacuolar degeneration in neurons in Alzheimer's disease. Acta Neuropathol (2001) 1.15
Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation. Mol Cell Biol (2005) 1.12
Glycogen synthase kinase-3beta heterozygote knockout mice as a model of findings in postmortem schizophrenia brain or as a model of behaviors mimicking lithium action: negative results. Behav Pharmacol (2008) 1.12
GSK3: an in-Toll-erant protein kinase? Nat Immunol (2005) 1.11
Glycogen synthase kinase 3beta is a negative regulator of growth factor-induced activation of the c-Jun N-terminal kinase. J Biol Chem (2004) 1.09
Assessment of social interaction behaviors. J Vis Exp (2011) 1.09
NF-kappaB couples protein kinase B/Akt signaling to distinct survival pathways and the regulation of lymphocyte homeostasis in vivo. J Immunol (2005) 1.08
Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes. J Clin Invest (2008) 1.07
Does GSK-3 provide a shortcut for PI3K activation of Wnt signalling? F1000 Biol Rep (2010) 1.07
Negative regulation of phosphatidylinositol 3-kinase and Akt signalling pathway by PKC. Cell Signal (2003) 1.06
Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link in the therapeutic action of lithium. J Circadian Rhythms (2007) 1.01
Role of the Phox homology domain and phosphorylation in activation of serum and glucocorticoid-regulated kinase-3. J Biol Chem (2006) 1.00
Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3. Synapse (2011) 0.99
Specific deletion of glycogen synthase kinase-3β in the renal proximal tubule protects against acute nephrotoxic injury in mice. Kidney Int (2012) 0.98
Inactivation of the enzyme GSK3α by the kinase IKKi promotes AKT-mTOR signaling pathway that mediates interleukin-1-induced Th17 cell maintenance. Immunity (2012) 0.97
Expression of Wnt-signaling pathway proteins in intraductal papillary mucinous neoplasms of the pancreas: a tissue microarray analysis. Hum Pathol (2006) 0.97
Exploring pluripotency with chemical genetics. Cell Stem Cell (2009) 0.95
Towards the preparation of radiolabeled 1-aryl-3-benzyl ureas: Radiosynthesis of [(11)C-carbonyl] AR-A014418 by [(11)C]CO(2) fixation. Bioorg Med Chem Lett (2012) 0.94
Regulation of Th1 cells and experimental autoimmune encephalomyelitis by glycogen synthase kinase-3. J Immunol (2013) 0.93
Frequent accumulation of nuclear E-cadherin and alterations in the Wnt signaling pathway in esophageal squamous cell carcinomas. Mod Pathol (2007) 0.93
Targeting glycogen synthase kinase-3 (GSK-3) in the treatment of Type 2 diabetes. Expert Opin Ther Targets (2008) 0.92
Inhibitory phosphorylation of GSK-3 by CaMKII couples depolarization to neuronal survival. J Biol Chem (2010) 0.92
Differential gene expression profile reveals deregulation of pregnancy specific beta1 glycoprotein 9 early during colorectal carcinogenesis. BMC Cancer (2005) 0.91
GSK-3α and GSK-3β proteins are involved in early stages of chondrocyte differentiation with functional redundancy through RelA protein phosphorylation. J Biol Chem (2012) 0.91
Homozygous deletion of glycogen synthase kinase 3beta bypasses senescence allowing Ras transformation of primary murine fibroblasts. Proc Natl Acad Sci U S A (2008) 0.90
Selective loss of glycogen synthase kinase-3α in birds reveals distinct roles for GSK-3 isozymes in tau phosphorylation. FEBS Lett (2011) 0.85
Utility of metformin in breast cancer treatment, is neoangiogenesis a risk factor? Breast Cancer Res Treat (2008) 0.84
Neuronal deletion of GSK3β increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2. BMC Biol (2014) 0.84
Chronic activation of protein kinase Bbeta/Akt2 leads to multinucleation and cell fusion in human epithelial kidney cells: events associated with tumorigenesis. Oncogene (2005) 0.84
Tissue-specific analysis of glycogen synthase kinase-3α (GSK-3α) in glucose metabolism: effect of strain variation. PLoS One (2011) 0.83
Genetic inactivation of GSK3α rescues spine deficits in Disc1-L100P mutant mice. Schizophr Res (2011) 0.83
Modulating autoimmunity: pick your PI3 kinase. Nat Med (2005) 0.80
Can a two-faced kinase be exploited for osteosarcoma? J Natl Cancer Inst (2012) 0.80
JNK1 activity lowers the cellular production of H2O2 and modulates the growth arrest response to scavenging of H2O2 by catalase. Exp Cell Res (2003) 0.79
The responses of neural stem cells to the level of GSK-3 depend on the tissue of origin. Biol Open (2013) 0.76
Rationally designed PKA inhibitors for positron emission tomography: Synthesis and cerebral biodistribution of N-(2-(4-bromocinnamylamino)ethyl)-N-[11C]methyl-isoquinoline-5-sulfonamide. Bioorg Med Chem (2008) 0.75
Regulation of the protein kinase activity of ShaggyZeste-white3 by components of the Wingless pathway in Drosophila cells and embryos. J Biol Chem (2016) 0.75