Published in Mol Cell Proteomics on May 15, 2010
The exoribonuclease Nibbler controls 3' end processing of microRNAs in Drosophila. Curr Biol (2011) 1.56
Rapid and specific purification of Argonaute-small RNA complexes from crude cell lysates. RNA (2012) 1.00
Blanks, a nuclear siRNA/dsRNA-binding complex component, is required for Drosophila spermiogenesis. Proc Natl Acad Sci U S A (2011) 0.83
Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci U S A (1998) 192.97
MicroRNAs: target recognition and regulatory functions. Cell (2009) 92.17
Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. Anal Chem (2002) 35.30
Argonaute2 is the catalytic engine of mammalian RNAi. Science (2004) 22.86
Origins and Mechanisms of miRNAs and siRNAs. Cell (2009) 20.77
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell (2000) 20.32
Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans. Cell (2006) 15.12
Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell (2004) 13.51
Crystal structure of Argonaute and its implications for RISC slicer activity. Science (2004) 12.48
Genetic and functional diversification of small RNA pathways in plants. PLoS Biol (2004) 12.21
The small RNA profile during Drosophila melanogaster development. Dev Cell (2003) 11.46
Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes. Nature (2008) 10.71
ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell (2001) 10.20
Regulatory RNAs in bacteria. Cell (2009) 9.57
R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science (2003) 9.53
Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell (2005) 9.35
Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways. Genes Dev (2004) 9.32
CRISPR--a widespread system that provides acquired resistance against phages in bacteria and archaea. Nat Rev Microbiol (2008) 8.91
Small RNAs as guardians of the genome. Cell (2009) 8.88
Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells. Science (2008) 8.62
Two classes of short interfering RNA in RNA silencing. EMBO J (2002) 8.54
Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev (1999) 8.21
An endogenous small interfering RNA pathway in Drosophila. Nature (2008) 7.88
A protein sensor for siRNA asymmetry. Science (2004) 7.77
The promises and pitfalls of RNA-interference-based therapeutics. Nature (2009) 7.53
Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs. Genes Dev (2008) 7.07
Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation. Cell (2005) 6.47
A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila. Cell (2004) 5.69
Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells. Nature (2008) 5.59
The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs. Nature (2008) 5.05
RISC assembly defects in the Drosophila RNAi mutant armitage. Cell (2004) 4.88
Genome-wide analysis of mRNAs regulated by Drosha and Argonaute proteins in Drosophila melanogaster. Mol Cell Biol (2006) 3.80
RNAi in budding yeast. Science (2009) 3.32
Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry. Mol Cell Biol (2002) 3.10
The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing. Nat Cell Biol (2006) 2.83
RNA helicase A interacts with RISC in human cells and functions in RISC loading. Mol Cell (2007) 2.72
A genomewide screen for components of the RNAi pathway in Drosophila cultured cells. Proc Natl Acad Sci U S A (2006) 2.04
Dicer-2 and R2D2 coordinately bind siRNA to promote assembly of the siRISC complexes. RNA (2006) 1.98
Conversion of pre-RISC to holo-RISC by Ago2 during assembly of RNAi complexes. RNA (2006) 1.85
G-patch: a new conserved domain in eukaryotic RNA-processing proteins and type D retroviral polyproteins. Trends Biochem Sci (1999) 1.82
Molecular requirements for RNA-induced silencing complex assembly in the Drosophila RNA interference pathway. J Biol Chem (2005) 1.62
An inside job for siRNAs. Mol Cell (2008) 1.29
The R3H motif: a domain that binds single-stranded nucleic acids. Trends Biochem Sci (1998) 1.05
Effective inhibition of human cytomegalovirus gene expression and growth by intracellular expression of external guide sequence RNA. RNA (2005) 0.86
Origins and Mechanisms of miRNAs and siRNAs. Cell (2009) 20.77
Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell (2004) 13.51
CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA. Science (2008) 11.82
CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea. Nat Rev Genet (2010) 7.47
Self versus non-self discrimination during CRISPR RNA-directed immunity. Nature (2010) 5.89
A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila. Cell (2004) 5.69
Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis. Proc Natl Acad Sci U S A (2013) 3.53
Silencing by small RNAs is linked to endosomal trafficking. Nat Cell Biol (2009) 3.25
Processing-independent CRISPR RNAs limit natural transformation in Neisseria meningitidis. Mol Cell (2013) 2.52
A role for ubiquitin in the spliceosome assembly pathway. Nat Struct Mol Biol (2008) 2.12
Molecular requirements for RNA-induced silencing complex assembly in the Drosophila RNA interference pathway. J Biol Chem (2005) 1.62
Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p. RNA (2006) 1.43
An inside job for siRNAs. Mol Cell (2008) 1.29
RNAi: RISC gets loaded. Cell (2005) 1.15
Short interfering RNA strand selection is independent of dsRNA processing polarity during RNAi in Drosophila. Curr Biol (2006) 1.11
Microbiology: slicer for DNA. Nature (2010) 1.10
"siRNAs and miRNAs": a meeting report on RNA silencing. RNA (2004) 1.02
Invasive DNA, chopped and in the CRISPR. Structure (2009) 0.99
ATP modulates siRNA interactions with an endogenous human Dicer complex. RNA (2005) 0.95
Meiosis-induced alterations in transcript architecture and noncoding RNA expression in S. cerevisiae. RNA (2012) 0.86
Methods in Enzymology. The use of CRISPR/Cas9, ZFNs, and TALENs in generating site-specific genome alterations. Preface. Methods Enzymol (2014) 0.84
Blanks, a nuclear siRNA/dsRNA-binding complex component, is required for Drosophila spermiogenesis. Proc Natl Acad Sci U S A (2011) 0.83
R2D2 leads the silencing trigger to mRNA's death star. Cell (2003) 0.78
Thermodynamic and structural characterization of 2'-nitrogen-modified RNA duplexes. Nucleic Acids Res (2004) 0.77
Separation of Drosophila RNA silencing complexes by native gel electrophoresis. Methods Mol Biol (2005) 0.76
A fork in the road for microRNAs. Nat Struct Mol Biol (2007) 0.76
The Making of an siRNA. Mol Cell (2004) 0.75
Quit stalling or you'll be silenced. Cell (2013) 0.75
Cis Editing in Trypanosoma brucei brucei as a Model for Understanding Guide-RNA Structural and Functional Requirements. Biol Bull (2004) 0.75
Type II-C CRISPR-Cas9 Biology, Mechanism and Application. ACS Chem Biol (2017) 0.75