In vivo evidence for the involvement of the carboxy terminal domain in assembling connexin 36 at the electrical synapse.

PubWeight™: 0.90‹?›

🔗 View Article (PMC 3025355)

Published in Mol Cell Neurosci on May 25, 2010

Authors

Ingo Helbig1, Esther Sammler, Marina Eliava, Alexey P Bolshakov, Andrei Rozov, Roberto Bruzzone, Hannah Monyer, Sheriar Gustad Hormuzdi

Author Affiliations

1: Department of Neuropediatrics, University Medical Center Schleswig-Holstein (UKSH), Schwanenweg 20, 24105 Kiel, Germany.

Articles citing this

Electrical synapses and their functional interactions with chemical synapses. Nat Rev Neurosci (2014) 1.24

Neuronal gap junctions: making and breaking connections during development and injury. Trends Neurosci (2012) 1.13

Gap junction-mediated electrical transmission: regulatory mechanisms and plasticity. Biochim Biophys Acta (2012) 1.06

Trafficking of gap junction channels at a vertebrate electrical synapse in vivo. Proc Natl Acad Sci U S A (2012) 0.95

Cx50 requires an intact PDZ-binding motif and ZO-1 for the formation of functional intercellular channels. Mol Biol Cell (2011) 0.93

Optogenetic mapping of cerebellar inhibitory circuitry reveals spatially biased coordination of interneurons via electrical synapses. Cell Rep (2014) 0.87

AII amacrine cells discriminate between heterocellular and homocellular locations when assembling connexin36-containing gap junctions. J Cell Sci (2014) 0.82

Estimating functional connectivity in an electrically coupled interneuron network. Proc Natl Acad Sci U S A (2013) 0.82

Connexin36 in gap junctions forming electrical synapses between motoneurons in sexually dimorphic motor nuclei in spinal cord of rat and mouse. Eur J Neurosci (2013) 0.81

A cataract-causing connexin 50 mutant is mislocalized to the ER due to loss of the fourth transmembrane domain and cytoplasmic domain. FEBS Open Bio (2012) 0.76

Electrotonic Coupling in the Pituitary Supports the Hypothalamic-Pituitary-Gonadal Axis in a Sex Specific Manner. Front Mol Neurosci (2016) 0.75

Chromosome loci vary by juvenile myoclonic epilepsy subsyndromes: linkage and haplotype analysis applied to epilepsy and EEG 3.5-6.0 Hz polyspike waves. Mol Genet Genomic Med (2016) 0.75

Connexin30.2: In Vitro Interaction with Connexin36 in HeLa Cells and Expression in AII Amacrine Cells and Intrinsically Photosensitive Ganglion Cells in the Mouse Retina. Front Mol Neurosci (2016) 0.75

Gap junctions and hemichannels: communicating cell death in neurodevelopment and disease. BMC Cell Biol (2017) 0.75

Articles cited by this

Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat Biotechnol (2004) 36.25

PDZ domain proteins of synapses. Nat Rev Neurosci (2004) 8.14

Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cells. J Cell Biol (1995) 4.08

Pannexins, a family of gap junction proteins expressed in brain. Proc Natl Acad Sci U S A (2003) 3.96

Synchronous activity of inhibitory networks in neocortex requires electrical synapses containing connexin36. Neuron (2001) 3.90

Connexin36 is essential for transmission of rod-mediated visual signals in the mammalian retina. Neuron (2002) 3.81

PDZ domains: structural modules for protein complex assembly. J Biol Chem (2001) 3.59

Impaired electrical signaling disrupts gamma frequency oscillations in connexin 36-deficient mice. Neuron (2001) 3.43

Clustering of connexin 43-enhanced green fluorescent protein gap junction channels and functional coupling in living cells. Proc Natl Acad Sci U S A (2000) 2.69

Zonula occludens-1 alters connexin43 gap junction size and organization by influencing channel accretion. Mol Biol Cell (2005) 2.62

Electrical synapses in the thalamic reticular nucleus. J Neurosci (2002) 2.47

In vivo labeling of parvalbumin-positive interneurons and analysis of electrical coupling in identified neurons. J Neurosci (2002) 2.38

Connexin36 mediates spike synchrony in olfactory bulb glomeruli. Neuron (2005) 2.26

A novel network of multipolar bursting interneurons generates theta frequency oscillations in neocortex. Neuron (2003) 2.05

AMPA receptors regulate dynamic equilibrium of presynaptic terminals in mature hippocampal networks. Nat Neurosci (2003) 1.96

Neurogliaform neurons form a novel inhibitory network in the hippocampal CA1 area. J Neurosci (2005) 1.95

Selective impairment of hippocampal gamma oscillations in connexin-36 knock-out mouse in vivo. J Neurosci (2003) 1.91

Electrical synapses define networks of neocortical GABAergic neurons. Trends Neurosci (2005) 1.85

Synaptic interactions of late-spiking neocortical neurons in layer 1. J Neurosci (2003) 1.77

Role of olivary electrical coupling in cerebellar motor learning. Neuron (2008) 1.67

Electrical synapses coordinate activity in the suprachiasmatic nucleus. Nat Neurosci (2004) 1.67

Long-term modulation of electrical synapses in the mammalian thalamus. Science (2005) 1.55

Gap-junctional coupling between neurogliaform cells and various interneuron types in the neocortex. J Neurosci (2005) 1.50

Networks of parvalbumin-positive interneurons in the basolateral amygdala. J Neurosci (2007) 1.44

Dopamine-stimulated dephosphorylation of connexin 36 mediates AII amacrine cell uncoupling. J Neurosci (2009) 1.43

Neuronal connexin36 association with zonula occludens-1 protein (ZO-1) in mouse brain and interaction with the first PDZ domain of ZO-1. Eur J Neurosci (2004) 1.39

RIC-3: a nicotinic acetylcholine receptor chaperone. Br J Pharmacol (2008) 1.38

Immunoreactivity for the GABAA receptor alpha1 subunit, somatostatin and Connexin36 distinguishes axoaxonic, basket, and bistratified interneurons of the rat hippocampus. Cereb Cortex (2006) 1.38

NMDA receptors regulate developmental gap junction uncoupling via CREB signaling. Nat Neurosci (2005) 1.37

Electrical synapses: a dynamic signaling system that shapes the activity of neuronal networks. Biochim Biophys Acta (2004) 1.31

Gap junctions among dendrites of cortical GABAergic neurons establish a dense and widespread intercolumnar network. J Neurosci (2006) 1.30

Two calretinin-positive GABAergic cell types in layer 2/3 of the mouse neocortex provide different forms of inhibition. Cereb Cortex (2008) 1.28

Molecular dissection of transjunctional voltage dependence in the connexin-32 and connexin-43 junctions. Biophys J (1999) 1.27

Connexin36 mediates gap junctional coupling of alpha-ganglion cells in mouse retina. J Comp Neurol (2005) 1.26

Effects of electrically coupled inhibitory networks on local neuronal responses to intracortical microstimulation. J Neurophysiol (2006) 1.22

Connexin-specific distribution within gap junctions revealed in living cells. J Cell Sci (2000) 1.22

Expression of connexin36 in cone pedicles and OFF-cone bipolar cells of the mouse retina. J Neurosci (2004) 1.18

Electrical coupling between interneurons with different excitable properties in the stratum lacunosum-moleculare of the juvenile CA1 rat hippocampus. J Neurosci (2005) 1.17

Sharp wave-like activity in the hippocampus in vitro in mice lacking the gap junction protein connexin 36. J Neurophysiol (2003) 1.16

Noradrenergic modulation of electrical coupling in GABAergic networks of the hippocampus. J Neurosci (2008) 1.12

Biophysical characterization of gap-junction channels in HeLa cells. Pflugers Arch (1993) 1.12

High-resolution proteomic mapping in the vertebrate central nervous system: close proximity of connexin35 to NMDA glutamate receptor clusters and co-localization of connexin36 with immunoreactivity for zonula occludens protein-1 (ZO-1). J Neurocytol (2004) 1.10

A new conditional mouse mutant reveals specific expression and functions of connexin36 in neurons and pancreatic beta-cells. Exp Cell Res (2008) 1.09

Stimulus complexity dependent memory impairment and changes in motor performance after deletion of the neuronal gap junction protein connexin36 in mice. Behav Brain Res (2005) 1.09

Network architecture of gap junction-coupled neuronal linkage in the striatum. J Neurosci (2009) 1.06

Association of connexin36 and zonula occludens-1 with zonula occludens-2 and the transcription factor zonula occludens-1-associated nucleic acid-binding protein at neuronal gap junctions in rodent retina. Neuroscience (2006) 1.03

Interaction between connexin35 and zonula occludens-1 and its potential role in the regulation of electrical synapses. Proc Natl Acad Sci U S A (2008) 1.02

Expression of chimeric connexins reveals new properties of the formation and gating behavior of gap junction channels. J Cell Sci (1994) 1.00

Evidence for a role of the N-terminal domain in subcellular localization of the neuronal connexin36 (Cx36). J Neurosci Res (2002) 0.96

Association of connexin36 with zonula occludens-1 in HeLa cells, betaTC-3 cells, pancreas, and adrenal gland. Histochem Cell Biol (2004) 0.95

Spatial relationships of connexin36, connexin57 and zonula occludens-1 in the outer plexiform layer of mouse retina. Neuroscience (2007) 0.94

ZO-1 and the spatial organization of gap junctions and glutamate receptors in the outer plexiform layer of the mammalian retina. J Neurosci (2009) 0.92

Intracellular potassium stabilizes human ether-à-go-go-related gene channels for export from endoplasmic reticulum. Mol Pharmacol (2009) 0.91

Immunohistochemical detection of the neuronal connexin36 in the mouse central nervous system in comparison to connexin36-deficient tissues. Histochem Cell Biol (2002) 0.91

Neuronal gap junctions in the mouse main olfactory bulb: morphological analyses on transgenic mice. Neuroscience (2005) 0.86

Structural organization of the gap junction network in the cerebral cortex. Neuroscientist (2007) 0.82

Articles by these authors

Pannexins, a family of gap junction proteins expressed in brain. Proc Natl Acad Sci U S A (2003) 3.96

Pharmacological properties of homomeric and heteromeric pannexin hemichannels expressed in Xenopus oocytes. J Neurochem (2005) 3.87

Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behavior. Neuron (2007) 3.67

Evoked axonal oxytocin release in the central amygdala attenuates fear response. Neuron (2012) 3.57

CKAMP44: a brain-specific protein attenuating short-term synaptic plasticity in the dentate gyrus. Science (2010) 3.17

Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal interneuron networks. Proc Natl Acad Sci U S A (2002) 2.92

New insights into the classification and nomenclature of cortical GABAergic interneurons. Nat Rev Neurosci (2013) 2.65

In vivo labeling of parvalbumin-positive interneurons and analysis of electrical coupling in identified neurons. J Neurosci (2002) 2.38

Targeted whole-cell recordings in the mammalian brain in vivo. Neuron (2003) 2.35

Hippocampal theta rhythm and its coupling with gamma oscillations require fast inhibition onto parvalbumin-positive interneurons. Proc Natl Acad Sci U S A (2009) 2.34

Stereotaxic gene delivery in the rodent brain. Nat Protoc (2006) 2.27

Connexin36 mediates spike synchrony in olfactory bulb glomeruli. Neuron (2005) 2.26

NMDA receptor ablation on parvalbumin-positive interneurons impairs hippocampal synchrony, spatial representations, and working memory. Neuron (2010) 2.21

Cell-cell communication beyond connexins: the pannexin channels. Physiology (Bethesda) (2006) 2.13

High-frequency network oscillations in cerebellar cortex. Neuron (2008) 2.12

Functional characterization of intrinsic cholinergic interneurons in the cortex. J Neurosci (2007) 2.08

A novel network of multipolar bursting interneurons generates theta frequency oscillations in neocortex. Neuron (2003) 2.05

ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner ear. Proc Natl Acad Sci U S A (2008) 2.01

Differential involvement of oriens/pyramidale interneurones in hippocampal network oscillations in vitro. J Physiol (2004) 2.00

Parvalbumin-containing fast-spiking basket cells generate the field potential oscillations induced by cholinergic receptor activation in the hippocampus. J Neurosci (2010) 1.93

Ca2+ buffer saturation underlies paired pulse facilitation in calbindin-D28k-containing terminals. Neuron (2003) 1.88

A role for fast rhythmic bursting neurons in cortical gamma oscillations in vitro. Proc Natl Acad Sci U S A (2004) 1.80

GABAergic interneurons shape the functional maturation of the cortex. Neuron (2013) 1.79

Single fluorescent protein-based Ca2+ sensors with increased dynamic range. BMC Biotechnol (2007) 1.79

Neurogenesis and widespread forebrain migration of distinct GABAergic neurons from the postnatal subventricular zone. Proc Natl Acad Sci U S A (2008) 1.78

Contribution of hippocampal and extra-hippocampal NR2B-containing NMDA receptors to performance on spatial learning tasks. Neuron (2008) 1.78

Orthogonal arrangement of rhythm-generating microcircuits in the hippocampus. Proc Natl Acad Sci U S A (2005) 1.71

Tumor-suppressive effects of pannexin 1 in C6 glioma cells. Cancer Res (2007) 1.70

Role of olivary electrical coupling in cerebellar motor learning. Neuron (2008) 1.67

Pannexin1 and Pannexin2 expression in the developing and mature rat brain. Brain Res Mol Brain Res (2005) 1.67

Connexin-dependent inter-cellular communication increases invasion and dissemination of Shigella in epithelial cells. Nat Cell Biol (2003) 1.66

Long-range-projecting GABAergic neurons modulate inhibition in hippocampus and entorhinal cortex. Science (2012) 1.58

Pannexins in ischemia-induced neurodegeneration. Proc Natl Acad Sci U S A (2011) 1.55

A juvenile form of postsynaptic hippocampal long-term potentiation in mice deficient for the AMPA receptor subunit GluR-A. J Physiol (2003) 1.52

Specific gene transfer to neurons, endothelial cells and hematopoietic progenitors with lentiviral vectors. Nat Methods (2010) 1.48

Open source clinical science for emerging infections. Lancet Infect Dis (2014) 1.47

The integrity of cholinergic basal forebrain neurons depends on expression of Nkx2-1. Eur J Neurosci (2011) 1.46

Excitotoxicity in vitro by NR2A- and NR2B-containing NMDA receptors. Neuropharmacology (2007) 1.44

Contrasting roles of axonal (pyramidal cell) and dendritic (interneuron) electrical coupling in the generation of neuronal network oscillations. Proc Natl Acad Sci U S A (2003) 1.38

Synaptic imbalance, stereotypies, and impaired social interactions in mice with altered neuroligin 2 expression. J Neurosci (2008) 1.35

Serotonin 3A receptor subtype as an early and protracted marker of cortical interneuron subpopulations. Cereb Cortex (2010) 1.33

Electrical synapses: a dynamic signaling system that shapes the activity of neuronal networks. Biochim Biophys Acta (2004) 1.31

GABAergic excitation in the basolateral amygdala. J Neurosci (2006) 1.30

A molecular basis of analgesic tolerance to cannabinoids. J Neurosci (2007) 1.28

Two calretinin-positive GABAergic cell types in layer 2/3 of the mouse neocortex provide different forms of inhibition. Cereb Cortex (2008) 1.28

Connexin36 mediates gap junctional coupling of alpha-ganglion cells in mouse retina. J Comp Neurol (2005) 1.26

Connexin30 mutations responsible for hidrotic ectodermal dysplasia cause abnormal hemichannel activity. Hum Mol Genet (2004) 1.23

Effects of electrically coupled inhibitory networks on local neuronal responses to intracortical microstimulation. J Neurophysiol (2006) 1.22

The N-terminal region of reelin regulates postnatal dendritic maturation of cortical pyramidal neurons. Proc Natl Acad Sci U S A (2009) 1.22

Bergmann glial AMPA receptors are required for fine motor coordination. Science (2012) 1.18

Expression of connexin36 in cone pedicles and OFF-cone bipolar cells of the mouse retina. J Neurosci (2004) 1.18

Transient depression of excitatory synapses on interneurons contributes to epileptiform bursts during gamma oscillations in the mouse hippocampal slice. J Neurophysiol (2005) 1.18

Actin/alpha-actinin-dependent transport of AMPA receptors in dendritic spines: role of the PDZ-LIM protein RIL. J Neurosci (2004) 1.17

Diazepam binding inhibitor promotes progenitor proliferation in the postnatal SVZ by reducing GABA signaling. Cell Stem Cell (2012) 1.17

Sharp wave-like activity in the hippocampus in vitro in mice lacking the gap junction protein connexin 36. J Neurophysiol (2003) 1.16

Features of neuronal synchrony in mouse visual cortex. J Neurophysiol (2003) 1.16

Pathogenetic role of the deafness-related M34T mutation of Cx26. Hum Mol Genet (2006) 1.14

Regulation of body temperature and neuroprotection by endogenous interleukin-6 in cerebral ischemia. J Cereb Blood Flow Metab (2003) 1.13

Efficient assembly and secretion of recombinant subviral particles of the four dengue serotypes using native prM and E proteins. PLoS One (2009) 1.13

Virtual cloning, functional expression, and gating analysis of human connexin31.9. Am J Physiol Cell Physiol (2002) 1.10

Two variants of the rat brain sodium-driven chloride bicarbonate exchanger (NCBE): developmental expression and addition of a PDZ motif. Eur J Neurosci (2003) 1.10

Hearing loss: frequency and functional studies of the most common connexin26 alleles. Biochem Biophys Res Commun (2002) 1.09

The long and short of GABAergic neurons. Curr Opin Neurobiol (2013) 1.09

H5-type influenza virus hemagglutinin is functionally recognized by the natural killer-activating receptor NKp44. J Virol (2007) 1.08

Hemichannels in cerebral ischemia. Curr Mol Med (2009) 1.07

Gene expression analysis of in vivo fluorescent cells. PLoS One (2007) 1.06

Increased subventricular zone-derived cortical neurogenesis after ischemic lesion. Exp Neurol (2010) 1.05

Cell coupling and Cx43 expression in embryonic mouse neural progenitor cells. J Cell Sci (2002) 1.05

Cleavage of the SARS coronavirus spike glycoprotein by airway proteases enhances virus entry into human bronchial epithelial cells in vitro. PLoS One (2009) 1.05

Analysis of the effects of cannabinoids on identified synaptic connections in the caudate-putamen by paired recordings in transgenic mice. J Physiol (2006) 1.04

Disruption of cardiac Ena-VASP protein localization in intercalated disks causes dilated cardiomyopathy. Am J Physiol Heart Circ Physiol (2003) 1.04

Modulation of perch connexin35 hemi-channels by cyclic AMP requires a protein kinase A phosphorylation site. J Neurosci Res (2003) 1.04

Class II ADP-ribosylation factors are required for efficient secretion of dengue viruses. J Biol Chem (2011) 1.02

The SARS coronavirus E protein interacts with PALS1 and alters tight junction formation and epithelial morphogenesis. Mol Biol Cell (2010) 1.01

Presynaptic Ca2+ dynamics, Ca2+ buffers and synaptic efficacy. Cell Calcium (2005) 1.01

Input-output features of anatomically identified CA3 neurons during hippocampal sharp wave/ripple oscillation in vitro. J Neurosci (2013) 1.00

Functional outcome of pannexin-deficient mice after cerebral ischemia. Channels (Austin) (2012) 0.99

A BCR-JAK2 fusion gene as the result of a t(9;22)(p24;q11) in a patient with acute myeloid leukemia. Cancer Genet Cytogenet (2008) 0.99

The role of electrical signaling via gap junctions in the generation of fast network oscillations. Brain Res Bull (2003) 0.99

Target-specific regulation of synaptic amplitudes in the neocortex. J Neurosci (2005) 0.98

Thyroid hormone is required for hypothalamic neurons regulating cardiovascular functions. J Clin Invest (2012) 0.98

Human-specific endogenous retroviral insert serves as an enhancer for the schizophrenia-linked gene PRODH. Proc Natl Acad Sci U S A (2013) 0.96

A reporter allele for investigating connexin 26 gene expression in the mouse brain. Eur J Neurosci (2003) 0.96

Fluorescent Arc/Arg3.1 indicator mice: a versatile tool to study brain activity changes in vitro and in vivo. J Neurosci Methods (2009) 0.95

Mice with genetically altered glutamate receptors as models of schizophrenia: a comprehensive review. Neurosci Biobehav Rev (2009) 0.94

Major signaling pathways in migrating neuroblasts. Front Mol Neurosci (2009) 0.94

Molecular diversity of neocortical GABAergic interneurones. J Physiol (2004) 0.93

EphA4 preserves postnatal and adult neural stem cells in an undifferentiated state in vivo. J Cell Sci (2011) 0.93

Augmented hippocampal ripple oscillations in mice with reduced fast excitation onto parvalbumin-positive cells. J Neurosci (2009) 0.93

Anti-severe acute respiratory syndrome coronavirus spike antibodies trigger infection of human immune cells via a pH- and cysteine protease-independent FcγR pathway. J Virol (2011) 0.93