James J Collins

Author PubWeight™ 273.81‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Stochasticity in gene expression: from theories to phenotypes. Nat Rev Genet 2005 14.39
2 Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 2010 14.18
3 A common mechanism of cellular death induced by bactericidal antibiotics. Cell 2007 12.92
4 Large-scale mapping and validation of Escherichia coli transcriptional regulation from a compendium of expression profiles. PLoS Biol 2007 10.46
5 Inferring genetic networks and identifying compound mode of action via expression profiling. Science 2003 9.10
6 Synthetic biology: applications come of age. Nat Rev Genet 2010 6.96
7 Wisdom of crowds for robust gene network inference. Nat Methods 2012 6.91
8 Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis. Mol Cell 2010 5.33
9 Reverse engineering gene networks using singular value decomposition and robust regression. Proc Natl Acad Sci U S A 2002 5.29
10 Engineered riboregulators enable post-transcriptional control of gene expression. Nat Biotechnol 2004 5.07
11 Phenotypic consequences of promoter-mediated transcriptional noise. Mol Cell 2006 4.93
12 Reverse engineering gene networks: integrating genetic perturbations with dynamical modeling. Proc Natl Acad Sci U S A 2003 4.89
13 Programmable cells: interfacing natural and engineered gene networks. Proc Natl Acad Sci U S A 2004 4.72
14 How antibiotics kill bacteria: from targets to networks. Nat Rev Microbiol 2010 4.65
15 Synthetic gene networks that count. Science 2009 4.54
16 Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death. Cell 2008 4.47
17 Cellular decision making and biological noise: from microbes to mammals. Cell 2011 4.44
18 Metabolite-enabled eradication of bacterial persisters by aminoglycosides. Nature 2011 4.06
19 Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli. Mol Syst Biol 2007 3.98
20 Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks. Nat Biotechnol 2005 3.89
21 Diversity-based, model-guided construction of synthetic gene networks with predicted functions. Nat Biotechnol 2009 3.86
22 Bacterial charity work leads to population-wide resistance. Nature 2010 3.50
23 Programmable bacteria detect and record an environmental signal in the mammalian gut. Proc Natl Acad Sci U S A 2014 3.50
24 Vibrating insoles and balance control in elderly people. Lancet 2003 3.48
25 RNA synthetic biology. Nat Biotechnol 2006 3.37
26 Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells. Nat Biotechnol 2011 3.25
27 Next-generation synthetic gene networks. Nat Biotechnol 2009 3.12
28 Antibiotic treatment expands the resistance reservoir and ecological network of the phage metagenome. Nature 2013 3.02
29 Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy. Proc Natl Acad Sci U S A 2009 3.01
30 Signaling-mediated bacterial persister formation. Nat Chem Biol 2012 2.96
31 Reprogramming of T cells from human peripheral blood. Cell Stem Cell 2010 2.93
32 Dispersing biofilms with engineered enzymatic bacteriophage. Proc Natl Acad Sci U S A 2007 2.87
33 A tunable genetic switch based on RNAi and repressor proteins for regulating gene expression in mammalian cells. Cell 2007 2.83
34 Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli. Mol Cell 2009 2.74
35 Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics. Science 2012 2.72
36 Antibiotic-induced bacterial cell death exhibits physiological and biochemical hallmarks of apoptosis. Mol Cell 2012 2.56
37 Combinatorial promoter design for engineering noisy gene expression. Proc Natl Acad Sci U S A 2007 2.40
38 MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium. Proc Natl Acad Sci U S A 2009 2.37
39 Synthetic biology moving into the clinic. Science 2011 2.36
40 A synthetic biology framework for programming eukaryotic transcription functions. Cell 2012 2.32
41 Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma. Nat Med 2012 2.26
42 Synthetic gene network for entraining and amplifying cellular oscillations. Phys Rev Lett 2002 2.24
43 A network biology approach to prostate cancer. Mol Syst Biol 2007 2.07
44 Noise-enhanced balance control in patients with diabetes and patients with stroke. Ann Neurol 2006 2.06
45 The transcriptional landscape of hematopoietic stem cell ontogeny. Cell Stem Cell 2012 1.96
46 microRNA regulatory network inference identifies miR-34a as a novel regulator of TGF-β signaling in glioblastoma. Cancer Discov 2012 1.94
47 A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells. Nat Immunol 2012 1.93
48 Role of reactive oxygen species in antibiotic action and resistance. Curr Opin Microbiol 2009 1.92
49 Aging, muscle activity, and balance control: physiologic changes associated with balance impairment. Gait Posture 2003 1.84
50 Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. Cell Stem Cell 2013 1.68
51 Tracking, tuning, and terminating microbial physiology using synthetic riboregulators. Proc Natl Acad Sci U S A 2010 1.66
52 Genetic switchboard for synthetic biology applications. Proc Natl Acad Sci U S A 2012 1.60
53 Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production. Nat Biotechnol 2013 1.59
54 Tuning and controlling gene expression noise in synthetic gene networks. Nucleic Acids Res 2010 1.52
55 Heterogeneous bacterial persisters and engineering approaches to eliminate them. Curr Opin Microbiol 2011 1.47
56 Tunable signal processing in synthetic MAP kinase cascades. Cell 2011 1.45
57 Antibiotics and the gut microbiota. J Clin Invest 2014 1.39
58 Microbial persistence and the road to drug resistance. Cell Host Microbe 2013 1.37
59 Salmonella typhimurium intercepts Escherichia coli signaling to enhance antibiotic tolerance. Proc Natl Acad Sci U S A 2013 1.29
60 Fungicidal drugs induce a common oxidative-damage cellular death pathway. Cell Rep 2013 1.19
61 Transcriptome analysis identifies regulators of hematopoietic stem and progenitor cells. Stem Cell Reports 2013 1.19
62 Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli. Proc Natl Acad Sci U S A 2010 1.18
63 Iterative plug-and-play methodology for constructing and modifying synthetic gene networks. Nat Methods 2012 1.17
64 Unraveling the physiological complexities of antibiotic lethality. Annu Rev Pharmacol Toxicol 2014 1.16
65 Noise-enhanced balance control in older adults. Neuroreport 2002 1.16
66 Functional characterization of bacterial sRNAs using a network biology approach. Proc Natl Acad Sci U S A 2011 1.14
67 A network biology approach to aging in yeast. Proc Natl Acad Sci U S A 2009 1.11
68 Valproic acid extends Caenorhabditis elegans lifespan. Aging Cell 2008 1.10
69 Regulation of physiologic actions of LRRK2: focus on autophagy. Neurodegener Dis 2011 1.07
70 Functional genomic characterization of neoblast-like stem cells in larval Schistosoma mansoni. Elife 2013 1.07
71 Genomic approaches to deconstruct pluripotency. Annu Rev Genomics Hum Genet 2011 1.06
72 Noise-enhanced vibrotactile sensitivity in older adults, patients with stroke, and patients with diabetic neuropathy. Arch Phys Med Rehabil 2002 1.06
73 Silencing HoxA1 by intraductal injection of siRNA lipidoid nanoparticles prevents mammary tumor progression in mice. Sci Transl Med 2014 1.03
74 Reliability and validity of the Stanford Presenteeism Scale. J Occup Environ Med 2004 1.02
75 Microbial environments confound antibiotic efficacy. Nat Chem Biol 2011 0.99
76 Microbiology. Antioxidant strategies to tolerate antibiotics. Science 2011 0.95
77 Whole mount in situ hybridization methodology for Schistosoma mansoni. Mol Biochem Parasitol 2011 0.95
78 Systems biology strikes gold. Cell 2009 0.94
79 Mortality update of workers exposed to acrylonitrile in The Netherlands. J Occup Environ Med 2004 0.92
80 Predicting the dynamic postural control response from quiet-stance behavior in elderly adults. J Biomech 2003 0.92
81 Molecular biology. Signal processing in single cells. Science 2005 0.91
82 Enhancing tactile sensation in older adults with electrical noise stimulation. Neuroreport 2002 0.91
83 Incomplete follow-up in the National Cancer Institute's formaldehyde worker study and the impact on subsequent reanalyses and causal evaluations. Regul Toxicol Pharmacol 2010 0.90
84 Introduction to focus issue: quantitative approaches to genetic networks. Chaos 2013 0.89
85 Networking opportunities for bacteria. Cell 2008 0.88
86 Plug-and-play with RNA. Nat Biotechnol 2005 0.87
87 Central role for RNase YbeY in Hfq-dependent and Hfq-independent small-RNA regulation in bacteria. BMC Genomics 2014 0.87
88 Mortality in workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin at a trichlorophenol plant in New Zealand. J Occup Environ Med 2009 0.86
89 A sex-specific transcription factor controls male identity in a simultaneous hermaphrodite. Nat Commun 2013 0.86
90 Differential splicing across immune system lineages. Proc Natl Acad Sci U S A 2013 0.85
91 Translating the noise. Nat Genet 2002 0.83
92 Elimination rates of dioxin congeners in former chlorophenol workers from Midland, Michigan. Environ Health Perspect 2012 0.83
93 Size matters: network inference tackles the genome scale. Mol Syst Biol 2007 0.83
94 Rewiring bacteria, two components at a time. Cell 2008 0.82
95 Factors related to dioxin and furan body levels among Michigan workers. Environ Res 2007 0.82
96 Synthetic biology: How best to build a cell. Nature 2014 0.82
97 Low level occupational benzene exposure and hematological parameters. Chem Biol Interact 2010 0.81
98 And the noise played on: stochastic gene expression and HIV-1 infection. Cell 2005 0.81
99 Editorial-synthetic biology. Nucleic Acids Res 2010 0.80
100 Insulating gene circuits from context by RNA processing. Nat Biotechnol 2012 0.80
101 Acrylonitrile and cancer: a review of the epidemiology. Regul Toxicol Pharmacol 2008 0.79
102 Systems biology makes it personal. Mol Cell 2009 0.79
103 Combined administration of testosterone plus an ornithine decarboxylase inhibitor as a selective prostate-sparing anabolic therapy. Aging Cell 2013 0.77
104 Mortality in employees at a New Zealand agrochemical manufacturing site. Occup Med (Lond) 2009 0.76
105 Defining cellular identity through network biology. Cell Cycle 2014 0.76
106 Mortality study update of acrylamide workers. Occup Environ Med 2007 0.76
107 QnAs with James J. Collins. Proc Natl Acad Sci U S A 2015 0.75
108 Reply to Blair et al.: Dose-dependent effects and oxidative stress responses in antibiotic tolerance in Salmonella typhimurium. Proc Natl Acad Sci U S A 2013 0.75
109 Re: Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries. J Natl Cancer Inst 2004 0.75
110 Making a noisy gene: HDACs turn up the static. Mol Cell 2012 0.75
111 Cellular signal processing: out of one, many. Mol Cell 2012 0.75
112 Gene regulation: hacking the network on a sugar high. Mol Cell 2008 0.75
113 Bacteria as control engineers. Mol Cell 2011 0.75
114 Correction: Genome-Wide Analyses Reveal a Role for Peptide Hormones in Planarian Germline Development. PLoS Biol 2015 0.75
115 TCDD exposure estimation for workers at a New Zealand 2,4,5-T manufacturing facility based on serum sampling data. J Expo Sci Environ Epidemiol 2009 0.75
116 Mortality surveillance of a US wide cohort of chemical industry workers. J Occup Environ Med 2010 0.75
117 Neurobehavioral effects of occupational exposure to acrylonitrile in Chinese workers. Environ Toxicol Pharmacol 2005 0.75
118 A risk assessment for occupational acrylonitrile exposure using epidemiology data. Risk Anal 2004 0.75
119 Longitudinal and Cross-sectional Analyses of Lung Function in Toluene Diisocyanate Production Workers. J Occup Environ Med 2017 0.75
120 Weight-of-the-evidence review of acrylonitrile reproductive and developmental toxicity studies. Crit Rev Toxicol 2009 0.75
121 Expanding and enhancing our antibacterial arsenal. Curr Opin Microbiol 2011 0.75
122 Medical Monitoring for Occupational Asthma Among Toluene Diisocyanate Production Workers in the United States. J Occup Environ Med 2017 0.75
123 Forward engineering. Interview by Kristie Nybo. Biotechniques 2012 0.75
124 Mortality among chemical workers at Texas City plant: 1940-2001. Int Arch Occup Environ Health 2008 0.75