Published in J Immunol on June 16, 2010
Functions of T cells in asthma: more than just T(H)2 cells. Nat Rev Immunol (2010) 2.62
How tolerogenic dendritic cells induce regulatory T cells. Adv Immunol (2010) 2.11
Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3(+) T-regulatory cells. Mol Cell Biol (2011) 1.82
Sirtuin-1 targeting promotes Foxp3+ T-regulatory cell function and prolongs allograft survival. Mol Cell Biol (2011) 1.53
Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat Immunol (2011) 1.49
Inflammation and Nutritional Science for Programs/Policies and Interpretation of Research Evidence (INSPIRE). J Nutr (2015) 1.20
Next-generation insights into regulatory T cells: expression profiling and FoxP3 occupancy in Human. Nucleic Acids Res (2011) 1.14
FOXP3 orchestrates H4K16 acetylation and H3K4 trimethylation for activation of multiple genes by recruiting MOF and causing displacement of PLU-1. Mol Cell (2011) 1.14
Genome-wide DNA methylation analysis identifies hypomethylated genes regulated by FOXP3 in human regulatory T cells. Blood (2013) 1.01
Human regulatory T cells in autoimmune diseases. Curr Opin Immunol (2010) 0.95
Biomarkers of transplantation tolerance: more hopeful than helpful? Front Immunol (2011) 0.94
PIM1 kinase phosphorylates the human transcription factor FOXP3 at serine 422 to negatively regulate its activity under inflammation. J Biol Chem (2014) 0.86
Foxp3-mediated inhibition of Akt inhibits Glut1 (glucose transporter 1) expression in human T regulatory cells. J Leukoc Biol (2014) 0.86
DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions. Nucleic Acids Res (2015) 0.84
Forkhead transcription factor FOXP3 upregulates CD25 expression through cooperation with RelA/NF-κB. PLoS One (2012) 0.84
Regulatory T Cells Control Immune Responses through Their Non-Redundant Tissue Specific Features. Front Immunol (2013) 0.84
FOXP3: genetic and epigenetic implications for autoimmunity. J Autoimmun (2013) 0.83
Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3+ T-regulatory Cell Function and Promotes Antitumor Immunity. EBioMedicine (2016) 0.82
Clinical Potential of microRNA-7 in Cancer. J Clin Med (2015) 0.82
Environmental determinants of islet autoimmunity (ENDIA): a pregnancy to early life cohort study in children at-risk of type 1 diabetes. BMC Pediatr (2013) 0.80
Transcriptome profiling of human FoxP3(+) regulatory T cells. Hum Immunol (2015) 0.80
ChIP-on-chip analysis identifies IL-22 as direct target gene of ectopically expressed FOXP3 transcription factor in human T cells. BMC Genomics (2012) 0.80
FOXP3 is a direct target of miR15a/16 in umbilical cord blood regulatory T cells. Bone Marrow Transplant (2014) 0.79
YY1 inhibits differentiation and function of regulatory T cells by blocking Foxp3 expression and activity. Nat Commun (2016) 0.79
Foxp3 drives oxidative phosphorylation and protection from lipotoxicity. JCI Insight (2017) 0.78
Inflammatory regulatory T cells in the microenvironments of ulcerative colitis and colon carcinoma. Oncoimmunology (2016) 0.78
MiRNome and transcriptome aided pathway analysis in human regulatory T cells. Genes Immun (2014) 0.78
Blunted expression of miR-199a-5p in regulatory T cells of patients with chronic obstructive pulmonary disease compared to unaffected smokers. Clin Exp Immunol (2014) 0.78
T regulatory cell chemokine production mediates pathogenic T cell attraction and suppression. J Clin Invest (2016) 0.76
Genome-wide analysis of cancer cell-derived Foxp3 target genes in human tongue squamous cell carcinoma cells. Int J Oncol (2015) 0.76
Eosinophils from eosinophilic oesophagitis patients have T cell suppressive capacity and express FOXP3. Clin Exp Immunol (2016) 0.75
Single and combined effect of retinoic acid and rapamycin modulate the generation, activity and homing potential of induced human regulatory T cells. PLoS One (2017) 0.75
Preliminary study on decreasing the expression of FOXP3 with miR-155 to inhibit diffuse large B-cell lymphoma. Oncol Lett (2017) 0.75
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol (2008) 24.27
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res (2008) 7.45
MicroRNAs as regulators of epithelial-mesenchymal transition. Cell Cycle (2008) 4.81
Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression. Genes Dev (2009) 3.58
Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia. Nat Genet (2011) 3.41
Experimental strategies for microRNA target identification. Nucleic Acids Res (2011) 3.00
Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxia. Mol Biol Cell (2002) 2.61
An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol Biol Cell (2011) 2.49
IsomiRs--the overlooked repertoire in the dynamic microRNAome. Trends Genet (2012) 2.00
Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-alpha signaling. J Biol Chem (2002) 1.97
E-cadherin expression is regulated by miR-192/215 by a mechanism that is independent of the profibrotic effects of transforming growth factor-beta. Diabetes (2010) 1.85
c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells. J Exp Med (2009) 1.85
c-Rel is required for chromatin remodeling across the IL-2 gene promoter. J Immunol (2003) 1.64
The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. J Clin Invest (2011) 1.59
Histone dynamics on the interleukin-2 gene in response to T-cell activation. Mol Cell Biol (2005) 1.57
Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat Immunol (2011) 1.49
Isolation of whole mononuclear cells from peripheral blood and cord blood. Curr Protoc Immunol (2009) 1.48
Assessing IRES activity in the HIF-1alpha and other cellular 5' UTRs. RNA (2006) 1.45
The microRNA-200 family regulates epithelial to mesenchymal transition. ScientificWorldJournal (2008) 1.44
Genome-wide analysis of gene expression in T cells to identify targets of the NF-kappa B transcription factor c-Rel. J Immunol (2007) 1.43
Expression of toll-like receptors on B lymphocytes. Cell Immunol (2005) 1.33
Regulated post-transcriptional RNA cleavage diversifies the eukaryotic transcriptome. Genome Res (2010) 1.32
Human PABP binds AU-rich RNA via RNA-binding domains 3 and 4. Eur J Biochem (2004) 1.31
Mutational analysis of 105 mucopolysaccharidosis type VI patients. Hum Mutat (2007) 1.30
ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression. J Clin Invest (2012) 1.29
Identifying functional miRNA-mRNA regulatory modules with correspondence latent dirichlet allocation. Bioinformatics (2010) 1.28
An optimized algorithm for detecting and annotating regional differential methylation. BMC Bioinformatics (2013) 1.27
Mechanism of and requirement for estrogen-regulated MYB expression in estrogen-receptor-positive breast cancer cells. Proc Natl Acad Sci U S A (2007) 1.27
Down-regulation of the miRNA-200 family at the invasive front of colorectal cancers with degraded basement membrane indicates EMT is involved in cancer progression. Neoplasia (2013) 1.25
On measuring miRNAs after transient transfection of mimics or antisense inhibitors. PLoS One (2013) 1.24
Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage. Nucleic Acids Res (2011) 1.24
Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem-cell-like state. J Cell Sci (2013) 1.24
Changes in chromatin accessibility across the GM-CSF promoter upon T cell activation are dependent on nuclear factor kappaB proteins. J Exp Med (2003) 1.23
MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells. J Transl Med (2011) 1.22
Myc-modulated miR-9 makes more metastases. Nat Cell Biol (2010) 1.22
BMP4: its role in development of the hematopoietic system and potential as a hematopoietic growth factor. Stem Cells (2004) 1.18
The NF-κB transcription factor c-Rel is required for Th17 effector cell development in experimental autoimmune encephalomyelitis. J Immunol (2011) 1.15
microRNAs and EMT in mammary cells and breast cancer. J Mammary Gland Biol Neoplasia (2010) 1.14
The nucleotide-binding site of human sphingosine kinase 1. J Biol Chem (2002) 1.14
Axl mediates acquired resistance of head and neck cancer cells to the epidermal growth factor receptor inhibitor erlotinib. Mol Cancer Ther (2013) 1.14
Exploring complex miRNA-mRNA interactions with Bayesian networks by splitting-averaging strategy. BMC Bioinformatics (2009) 1.13
A multi-protein complex containing cold shock domain (Y-box) and polypyrimidine tract binding proteins forms on the vascular endothelial growth factor mRNA. Potential role in mRNA stabilization. Eur J Biochem (2004) 1.13
The transcription repressor, ZEB1, cooperates with CtBP2 and HDAC1 to suppress IL-2 gene activation in T cells. Int Immunol (2009) 1.10
Regulation of the IL-21 gene by the NF-κB transcription factor c-Rel. J Immunol (2010) 1.10
Reversal and prevention of arsenic-induced human bronchial epithelial cell malignant transformation by microRNA-200b. Toxicol Sci (2011) 1.09
A vascular cell-restricted RhoGAP, p73RhoGAP, is a key regulator of angiogenesis. Proc Natl Acad Sci U S A (2004) 1.04
The human IL-2 gene promoter can assemble a positioned nucleosome that becomes remodeled upon T cell activation. J Immunol (2002) 1.02
Induction of miR-21 by retinoic acid in estrogen receptor-positive breast carcinoma cells: biological correlates and molecular targets. J Biol Chem (2010) 1.01
Immune activation in irritable bowel syndrome: can neuroimmune interactions explain symptoms? Am J Gastroenterol (2013) 1.00
Expression of Toll-like receptors by neonatal leukocytes. Pediatr Allergy Immunol (2010) 0.97
Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML. Blood (2009) 0.97
Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common beta-subunit. Blood (2010) 0.97
Changes in the expression of miR-381 and miR-495 are inversely associated with the expression of the MDR1 gene and development of multi-drug resistance. PLoS One (2013) 0.97
Dynamic evolution of clonal epialleles revealed by methclone. Genome Biol (2014) 0.97
Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors. Proc Natl Acad Sci U S A (2012) 0.96
Specificity protein 1 (Sp1) maintains basal epithelial expression of the miR-200 family: implications for epithelial-mesenchymal transition. J Biol Chem (2014) 0.94
A high-throughput platform for lentiviral overexpression screening of the human ORFeome. PLoS One (2011) 0.94
Phosphorylation of cold shock domain/Y-box proteins by ERK2 and GSK3beta and repression of the human VEGF promoter. FEBS Lett (2005) 0.94
Isolation of antigen-specific B cells. Immunol Cell Biol (2003) 0.94
ProNGF mediates death of Natural Killer cells through activation of the p75NTR-sortilin complex. J Neuroimmunol (2010) 0.94
Inferring microRNA and transcription factor regulatory networks in heterogeneous data. BMC Bioinformatics (2013) 0.93
The GM-CSF receptor family: mechanism of activation and implications for disease. Growth Factors (2012) 0.93
Development of CD4+CD25+FoxP3+ regulatory T cells from cord blood hematopoietic progenitor cells. J Leukoc Biol (2008) 0.92
Genetic regulators of myelopoiesis and leukemic signaling identified by gene profiling and linear modeling. J Leukoc Biol (2006) 0.92
Inferring microRNA-mRNA causal regulatory relationships from expression data. Bioinformatics (2013) 0.92
GM-CSF promoter chromatin remodelling and gene transcription display distinct signal and transcription factor requirements. Nucleic Acids Res (2005) 0.91
Over-expression of cathepsin E and trefoil factor 1 in sessile serrated adenomas of the colorectum identified by gene expression analysis. Virchows Arch (2009) 0.90
HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia. Oncotarget (2013) 0.89
Functional cross-talk between cytokine receptors revealed by activating mutations in the extracellular domain of the beta-subunit of the GM-CSF receptor. J Leukoc Biol (2002) 0.89
Signalling by the βc family of cytokines. Cytokine Growth Factor Rev (2013) 0.88
Characterization of colonic and mesenteric lymph node dendritic cell subpopulations in a murine adoptive transfer model of inflammatory bowel disease. Inflamm Bowel Dis (2004) 0.88
A role for Ets1, synergizing with AP-1 and GATA-3 in the regulation of IL-5 transcription in mouse Th2 lymphocytes. Int Immunol (2005) 0.87
Clonal and lineage analysis of somatic DNMT3A and JAK2 mutations in a chronic phase polycythemia vera patient. Br J Haematol (2011) 0.87
Control of interleukin-2 gene transcription: a paradigm for inducible, tissue-specific gene expression. Vitam Horm (2006) 0.87
Attenuation of leakiness in doxycycline-inducible expression via incorporation of 3' AU-rich mRNA destabilizing elements. Biotechniques (2008) 0.86
The impact of CpG island on defining transcriptional activation of the mouse L1 retrotransposable elements. PLoS One (2010) 0.86
Plasticity of DNA methylation in mouse T cell activation and differentiation. BMC Mol Biol (2012) 0.86
Monoclonal antibodies to human cell surface antigens. Curr Protoc Immunol (2008) 0.86
The granulocyte-associated transcription factor Krüppel-like factor 5 is silenced by hypermethylation in acute myeloid leukemia. Leuk Res (2011) 0.86
Long-term erythropoietin gene expression from transduced cells in bioisolator devices. Hum Gene Ther (2003) 0.86
A novel mechanism of repression of the vascular endothelial growth factor promoter, by single strand DNA binding cold shock domain (Y-box) proteins in normoxic fibroblasts. Nucleic Acids Res (2002) 0.85
Robust, reversible gene knockdown using a single lentiviral short hairpin RNA vector. Hum Gene Ther (2010) 0.85
DNA vaccines encoding membrane-bound or secreted forms of heat shock protein 70 exhibit improved potency. Eur J Immunol (2014) 0.84
The preferential occurrence of FLT3-TKD mutations in inv(16) AML and impact on survival outcome: a combined analysis of 1053 core-binding factor AML patients. Br J Haematol (2012) 0.84
Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27. Blood (2013) 0.84
The vent-like homeobox gene VENTX promotes human myeloid differentiation and is highly expressed in acute myeloid leukemia. Proc Natl Acad Sci U S A (2010) 0.83
Bone morphogenetic protein 4 contributes to the maintenance of primitive cord blood hematopoietic progenitors in an ex vivo stroma-noncontact co-culture system. Stem Cells Dev (2006) 0.83