Published in FASEB J on June 25, 2010
Structural studies of ROK fructokinase YdhR from Bacillus subtilis: insights into substrate binding and fructose specificity. J Mol Biol (2010) 0.91
Structural enzymology of Cellvibrio japonicus Agd31B protein reveals α-transglucosylase activity in glycoside hydrolase family 31. J Biol Chem (2012) 0.89
Molecular basis for the recognition of long-chain substrates by plant α-glucosidases. J Biol Chem (2013) 0.80
Structural advantage of sugar beet α-glucosidase to stabilize the Michaelis complex with long-chain substrate. J Biol Chem (2014) 0.77
Crystal structure of α-1,4-glucan lyase, a unique glycoside hydrolase family member with a novel catalytic mechanism. J Biol Chem (2013) 0.77
Using Carbohydrate Interaction Assays to Reveal Novel Binding Sites in Carbohydrate Active Enzymes. PLoS One (2016) 0.75
Molecular characterization of novel pyridoxal-5'-phosphate-dependent enzymes from the human microbiome. Protein Sci (2014) 0.75
Interaction mode between catalytic and regulatory subunits in glucosidase II involved in ER glycoprotein quality control. Protein Sci (2016) 0.75
Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr (2004) 227.01
The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr (1994) 187.88
Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr D Biol Crystallogr (1997) 137.43
A core gut microbiome in obese and lean twins. Nature (2008) 52.30
Diversity of the human intestinal microbial flora. Science (2005) 49.64
A human gut microbial gene catalogue established by metagenomic sequencing. Nature (2010) 43.63
The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics. Nucleic Acids Res (2008) 27.83
Substructure solution with SHELXD. Acta Crystallogr D Biol Crystallogr (2002) 27.16
Molecular replacement with MOLREP. Acta Crystallogr D Biol Crystallogr (2009) 26.26
An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system. Cell (2005) 15.46
Commensal host-bacterial relationships in the gut. Science (2001) 14.82
HKL-3000: the integration of data reduction and structure solution--from diffraction images to an initial model in minutes. Acta Crystallogr D Biol Crystallogr (2006) 13.29
Comparative metagenomics revealed commonly enriched gene sets in human gut microbiomes. DNA Res (2007) 13.08
Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin. J Mol Biol (1993) 11.24
Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells. Proc Natl Acad Sci U S A (2002) 9.78
Carbohydrate-binding modules: fine-tuning polysaccharide recognition. Biochem J (2004) 8.19
Structural and sequence-based classification of glycoside hydrolases. Curr Opin Struct Biol (1997) 7.71
The integrated microbial genomes system: an expanding comparative analysis resource. Nucleic Acids Res (2009) 6.07
Towards complete validated models in the next generation of ARP/wARP. Acta Crystallogr D Biol Crystallogr (2004) 5.90
Determination of maltase and isomaltase activities with a glucose-oxidase reagent. Biochem J (1961) 4.76
Nomenclature for sugar-binding subsites in glycosyl hydrolases. Biochem J (1997) 3.82
Genome-scale analyses of health-promoting bacteria: probiogenomics. Nat Rev Microbiol (2008) 3.25
Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice. FASEB J (2008) 2.97
The Polymerase Incomplete Primer Extension (PIPE) method applied to high-throughput cloning and site-directed mutagenesis. Methods Mol Biol (2009) 2.32
Comparison of bacterial diversity along the human intestinal tract by direct cloning and sequencing of 16S rRNA genes. FEMS Microbiol Ecol (2005) 2.18
Automation of protein purification for structural genomics. J Struct Funct Genomics (2004) 2.17
Metabolic diversity of the intestinal microbiota: implications for health and disease. J Nutr (2007) 1.70
Molecular analysis of jejunal, ileal, caecal and recto-sigmoidal human colonic microbiota using 16S rRNA gene libraries and terminal restriction fragment length polymorphism. J Med Microbiol (2005) 1.61
Evolution of function in (beta/alpha)8-barrel enzymes. Curr Opin Chem Biol (2003) 1.52
Recent advances and remaining gaps in our knowledge of associations between gut microbiota and human health. World J Gastroenterol (2009) 1.36
Intestinal flora and endogenous vitamin synthesis. Eur J Cancer Prev (1997) 1.33
Host-microbial symbiosis in the mammalian intestine: exploring an internal ecosystem. Bioessays (1998) 1.26
Human intestinal maltase-glucoamylase: crystal structure of the N-terminal catalytic subunit and basis of inhibition and substrate specificity. J Mol Biol (2007) 1.19
The maltase-glucoamylase gene: common ancestry to sucrase-isomaltase with complementary starch digestion activities. Proc Natl Acad Sci U S A (2003) 1.16
Mechanistic and structural analysis of a family 31 alpha-glycosidase and its glycosyl-enzyme intermediate. J Biol Chem (2004) 1.13
Microbial communities in the human small intestine: coupling diversity to metagenomics. Future Microbiol (2007) 1.07
Structure of the Sulfolobus solfataricus alpha-glucosidase: implications for domain conservation and substrate recognition in GH31. J Mol Biol (2006) 1.07
A study of four-helix bundles: investigating protein folding via similar architectural motifs in protein cores and in subunit interfaces. J Mol Biol (1995) 0.93
Innate and specific gut-associated immunity and microbial interference. FEMS Immunol Med Microbiol (2008) 0.87
Functional reconstitution of a maltose ATP-binding cassette transporter from the thermoacidophilic gram-positive bacterium Alicyclobacillus acidocaldarius. Biochim Biophys Acta (2004) 0.83
Structural insights into the substrate specificity and function of Escherichia coli K12 YgjK, a glucosidase belonging to the glycoside hydrolase family 63. J Mol Biol (2008) 0.82
Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand. Science (2002) 7.87
A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus. Science (2006) 7.84
Protein production and purification. Nat Methods (2008) 3.97
Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA. Nature (2002) 3.45
Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism. Nature (2006) 3.21
Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus. Nature (2008) 3.06
In situ proteolysis for protein crystallization and structure determination. Nat Methods (2007) 3.05
A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair. Mol Microbiol (2010) 2.70
Crystal structure of the CorA Mg2+ transporter. Nature (2006) 2.64
The Structural Biology Center 19ID undulator beamline: facility specifications and protein crystallographic results. J Synchrotron Radiat (2005) 2.62
An expression vector tailored for large-scale, high-throughput purification of recombinant proteins. Protein Expr Purif (2006) 2.58
Outcome of a workshop on archiving structural models of biological macromolecules. Structure (2006) 2.32
A family of LIC vectors for high-throughput cloning and purification of proteins. Methods Mol Biol (2009) 2.30
Crystal structure of the TSP-1 type 1 repeats: a novel layered fold and its biological implication. J Cell Biol (2002) 2.28
Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor. Genes Dev (2006) 2.23
Automation of protein purification for structural genomics. J Struct Funct Genomics (2004) 2.17
Structure of the influenza virus A H5N1 nucleoprotein: implications for RNA binding, oligomerization, and vaccine design. FASEB J (2008) 2.10
Outcome of a workshop on applications of protein models in biomedical research. Structure (2009) 2.05
Global profiling of Shewanella oneidensis MR-1: expression of hypothetical genes and improved functional annotations. Proc Natl Acad Sci U S A (2005) 1.93
Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet. EMBO J (2003) 1.89
Structure of RapA, a Swi2/Snf2 protein that recycles RNA polymerase during transcription. Structure (2008) 1.86
Triclinic lysozyme at 0.65 A resolution. Acta Crystallogr D Biol Crystallogr (2007) 1.77
Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases. Nat Struct Mol Biol (2008) 1.65
The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor. Nat Struct Biol (2002) 1.63
Identification of unknown protein function using metabolite cocktail screening. Structure (2012) 1.62
Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli. J Biol Chem (2003) 1.61
Staphylococcus aureus IsdG and IsdI, heme-degrading enzymes with structural similarity to monooxygenases. J Biol Chem (2004) 1.58
Large-scale evaluation of protein reductive methylation for improving protein crystallization. Nat Methods (2008) 1.55
Quantum model of catalysis based on a mobile proton revealed by subatomic x-ray and neutron diffraction studies of h-aldose reductase. Proc Natl Acad Sci U S A (2008) 1.55
Guidelines for reporting the use of gel electrophoresis in proteomics. Nat Biotechnol (2008) 1.54
Contributions to the NIH-NIGMS Protein Structure Initiative from the PSI Production Centers. Structure (2008) 1.52
B. subtilis ykuD protein at 2.0 A resolution: insights into the structure and function of a novel, ubiquitous family of bacterial enzymes. Proteins (2006) 1.47
Structural plasticity in the oestrogen receptor ligand-binding domain. EMBO Rep (2007) 1.47
Time-controlled microfluidic seeding in nL-volume droplets to separate nucleation and growth stages of protein crystallization. Angew Chem Int Ed Engl (2006) 1.45
High-throughput protein purification and quality assessment for crystallization. Methods (2011) 1.44
Crystal structure of Enterococcus faecalis SlyA-like transcriptional factor. J Biol Chem (2003) 1.42
Structure- and function-based characterization of a new phosphoglycolate phosphatase from Thermoplasma acidophilum. J Biol Chem (2003) 1.41
Crystal structure of murine sCEACAM1a[1,4]: a coronavirus receptor in the CEA family. EMBO J (2002) 1.37
Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure. J Biol Chem (2006) 1.33
Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands. Chem Biol (2007) 1.31
Towards fully automated structure-based function prediction in structural genomics: a case study. J Mol Biol (2007) 1.26
The crystal structure of a TL/CD8alphaalpha complex at 2.1 A resolution: implications for modulation of T cell activation and memory. Immunity (2003) 1.25
The structures of the thrombospondin-1 N-terminal domain and its complex with a synthetic pentameric heparin. Structure (2006) 1.25
Structural basis for dimerization of ICAM-1 on the cell surface. Mol Cell (2004) 1.24
Structure of the retinal determination protein Dachshund reveals a DNA binding motif. Structure (2002) 1.22
Crystal structure of Thermotoga maritima 0065, a member of the IclR transcriptional factor family. J Biol Chem (2002) 1.20
Protein surface analysis for function annotation in high-throughput structural genomics pipeline. Protein Sci (2005) 1.20
Bifidobacterium longum subsp. infantis ATCC 15697 α-fucosidases are active on fucosylated human milk oligosaccharides. Appl Environ Microbiol (2011) 1.20
Dodecamer structure of severe acute respiratory syndrome coronavirus nonstructural protein nsp10. J Virol (2006) 1.19
Structure of apo- and monometalated forms of NDM-1--a highly potent carbapenem-hydrolyzing metallo-β-lactamase. PLoS One (2011) 1.19
Structures of sortase B from Staphylococcus aureus and Bacillus anthracis reveal catalytic amino acid triad in the active site. Structure (2004) 1.18
Structural genomics: keeping up with expanding knowledge of the protein universe. Curr Opin Struct Biol (2007) 1.17
The structure and ligand binding properties of the B. subtilis YkoF gene product, a member of a novel family of thiamin/HMP-binding proteins. J Mol Biol (2004) 1.17
Biochemical and structural characterization of a novel family of cystathionine beta-synthase domain proteins fused to a Zn ribbon-like domain. J Mol Biol (2007) 1.16
Structural basis of membrane targeting by the Phox homology domain of cytokine-independent survival kinase (CISK-PX). J Biol Chem (2004) 1.16
Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis. Biochemistry (2008) 1.15
Structure of surface layer homology (SLH) domains from Bacillus anthracis surface array protein. J Biol Chem (2011) 1.12
Structural insight into the mechanism of c-di-GMP hydrolysis by EAL domain phosphodiesterases. J Mol Biol (2010) 1.12
Crystal structure of tabtoxin resistance protein complexed with acetyl coenzyme A reveals the mechanism for beta-lactam acetylation. J Mol Biol (2003) 1.12
New antiviral target revealed by the hexameric structure of mouse hepatitis virus nonstructural protein nsp15. J Virol (2006) 1.11
Comparative analysis of 10 small molecules binding to carbonic anhydrase II by different investigators using Biacore technology. Anal Biochem (2006) 1.11
Structure of Escherichia coli ribose-5-phosphate isomerase: a ubiquitous enzyme of the pentose phosphate pathway and the Calvin cycle. Structure (2003) 1.11
Protein functional surfaces: global shape matching and local spatial alignments of ligand binding sites. BMC Struct Biol (2008) 1.09
Optimization of benzoxazole-based inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase. J Med Chem (2013) 1.09
Activation of inhibitors by sortase triggers irreversible modification of the active site. J Biol Chem (2007) 1.09
A conformational switch controls cell wall-remodelling enzymes required for bacterial cell division. Mol Microbiol (2012) 1.08
C-banded karyotypes of two Silene species with heteromorphic sex chromosomes. Genome (2002) 1.07
Capsule anchoring in Bacillus anthracis occurs by a transpeptidation reaction that is inhibited by capsidin. Mol Microbiol (2008) 1.06
Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis. Proc Natl Acad Sci U S A (2008) 1.06
Receptor for advanced glycation endproducts mediates neutrophil migration across intestinal epithelium. J Immunol (2007) 1.05
Crystal structure of secretory protein Hcp3 from Pseudomonas aeruginosa. J Struct Funct Genomics (2011) 1.05
Deep trefoil knot implicated in RNA binding found in an archaebacterial protein. Proteins (2003) 1.05
Extracytoplasmic PAS-like domains are common in signal transduction proteins. J Bacteriol (2009) 1.05
Target selection and determination of function in structural genomics. IUBMB Life (2003) 1.05
Predicting protein crystallization propensity from protein sequence. J Struct Funct Genomics (2010) 1.04
Harvesting the high-hanging fruit: the structure of the YdeN gene product from Bacillus subtilis at 1.8 angstroms resolution. Acta Crystallogr D Biol Crystallogr (2004) 1.04
Structural basis and catalytic mechanism for the dual functional endo-beta-N-acetylglucosaminidase A. PLoS One (2009) 1.04
Crystal structure of a novel shikimate dehydrogenase from Haemophilus influenzae. J Biol Chem (2005) 1.03
NDM-1, the ultimate promiscuous enzyme: substrate recognition and catalytic mechanism. FASEB J (2013) 1.02
Structural basis for catalysis by the mono- and dimetalated forms of the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase. J Mol Biol (2010) 1.02
Characterization of a Bacillus subtilis transporter for petrobactin, an anthrax stealth siderophore. Proc Natl Acad Sci U S A (2009) 1.01
Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains. J Med Chem (2007) 1.01
The membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus binds the dipeptide GlyMet via side chain interactions. Biochemistry (2004) 1.01
Structural and biochemical characterization of the type II fructose-1,6-bisphosphatase GlpX from Escherichia coli. J Biol Chem (2008) 1.00
Heparin-induced cis- and trans-dimerization modes of the thrombospondin-1 N-terminal domain. J Biol Chem (2007) 1.00
The 2.2 A resolution structure of RpiB/AlsB from Escherichia coli illustrates a new approach to the ribose-5-phosphate isomerase reaction. J Mol Biol (2003) 1.00
The crystal structure of Escherichia coli MoaB suggests a probable role in molybdenum cofactor synthesis. J Biol Chem (2004) 1.00
Structures of open (R) and close (T) states of prephenate dehydratase (PDT)--implication of allosteric regulation by L-phenylalanine. J Struct Biol (2007) 0.99
Crystal structure of the dachshund homology domain of human SKI. Structure (2004) 0.99
Structure of transcription factor HetR required for heterocyst differentiation in cyanobacteria. Proc Natl Acad Sci U S A (2011) 0.99
The structural basis for methylmalonic aciduria. The crystal structure of archaeal ATP:cobalamin adenosyltransferase. J Biol Chem (2004) 0.99
Ultrahigh-resolution study of protein atomic displacement parameters at cryotemperatures obtained with a helium cryostat. Acta Crystallogr D Biol Crystallogr (2006) 0.98
Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteria. Proc Natl Acad Sci U S A (2008) 0.98