1
|
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes.
|
Autophagy
|
2007
|
20.92
|
2
|
Guidelines for the use and interpretation of assays for monitoring autophagy.
|
Autophagy
|
2012
|
20.08
|
3
|
5H-Dibenzo[c,h]1,6-naphthyridin-6-ones: novel topoisomerase I-targeting anticancer agents with potent cytotoxic activity.
|
Bioorg Med Chem
|
2003
|
3.13
|
4
|
Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells.
|
Biochem Pharmacol
|
2008
|
2.56
|
5
|
eEF-2 kinase dictates cross-talk between autophagy and apoptosis induced by Akt Inhibition, thereby modulating cytotoxicity of novel Akt inhibitor MK-2206.
|
Cancer Res
|
2011
|
2.10
|
6
|
Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells.
|
Autophagy
|
2009
|
2.09
|
7
|
Elongation factor-2 kinase regulates autophagy in human glioblastoma cells.
|
Cancer Res
|
2006
|
1.89
|
8
|
Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells.
|
Cancer Res
|
2003
|
1.71
|
9
|
Effect of stathmin on the sensitivity to antimicrotubule drugs in human breast cancer.
|
Cancer Res
|
2002
|
1.56
|
10
|
Transcription-dependent degradation of topoisomerase I-DNA covalent complexes.
|
Mol Cell Biol
|
2003
|
1.43
|
11
|
Silencing of elongation factor-2 kinase potentiates the effect of 2-deoxy-D-glucose against human glioma cells through blunting of autophagy.
|
Cancer Res
|
2009
|
1.42
|
12
|
MK-2206, a novel allosteric inhibitor of Akt, synergizes with gefitinib against malignant glioma via modulating both autophagy and apoptosis.
|
Mol Cancer Ther
|
2011
|
1.33
|
13
|
Identification and characterization of an inhibitor of eukaryotic elongation factor 2 kinase against human cancer cell lines.
|
Cancer Res
|
2003
|
1.33
|
14
|
Reversal of stathmin-mediated resistance to paclitaxel and vinblastine in human breast carcinoma cells.
|
Mol Pharmacol
|
2007
|
1.29
|
15
|
Therapeutic targeting of autophagy in disease: biology and pharmacology.
|
Pharmacol Rev
|
2013
|
1.25
|
16
|
Regulation of the stability of P-glycoprotein by ubiquitination.
|
Mol Pharmacol
|
2004
|
1.19
|
17
|
Involvement of CtBP1 in the transcriptional activation of the MDR1 gene in human multidrug resistant cancer cells.
|
Biochem Pharmacol
|
2007
|
1.14
|
18
|
EMMPRIN expression as a prognostic factor in radiotherapy of cervical cancer.
|
Clin Cancer Res
|
2008
|
1.11
|
19
|
Effect of a single nucleotide polymorphism in the murine double minute 2 promoter (SNP309) on the sensitivity to topoisomerase II-targeting drugs.
|
Cancer Res
|
2007
|
1.10
|
20
|
p300-Dependent ATF5 acetylation is essential for Egr-1 gene activation and cell proliferation and survival.
|
Mol Cell Biol
|
2011
|
1.08
|
21
|
Involvement of CD147 in regulation of multidrug resistance to P-gp substrate drugs and in vitro invasion in breast cancer cells.
|
Cancer Sci
|
2007
|
1.05
|
22
|
Interaction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAIL-induced apoptosis.
|
FEBS Lett
|
2010
|
1.05
|
23
|
Autophagic pathways as new targets for cancer drug development.
|
Acta Pharmacol Sin
|
2010
|
1.05
|
24
|
Elongation factor-2 kinase: its role in protein synthesis and autophagy.
|
Autophagy
|
2006
|
1.03
|
25
|
Endotoxins enhance hepatocarcinogenesis induced by oral intake of thioacetamide in rats.
|
World J Gastroenterol
|
1998
|
1.02
|
26
|
Identification of the ubiquitin-proteasome pathway in the regulation of the stability of eukaryotic elongation factor-2 kinase.
|
Cancer Res
|
2005
|
1.01
|
27
|
Altered energy metabolism in cancer: a unique opportunity for therapeutic intervention.
|
Cancer Biol Ther
|
2012
|
1.00
|
28
|
A matter of life or death (or both): understanding autophagy in cancer.
|
Clin Cancer Res
|
2006
|
0.99
|
29
|
Differential gene expression in tamoxifen-resistant breast cancer cells revealed by a new analytical model of RNA-Seq data.
|
PLoS One
|
2012
|
0.99
|
30
|
Detection of mutations in the mitogen-activated protein kinase pathway in human melanoma.
|
Clin Cancer Res
|
2003
|
0.95
|
31
|
Over-expression of ubiquitin carboxy terminal hydrolase-L1 induces apoptosis in breast cancer cells.
|
Int J Oncol
|
2008
|
0.95
|
32
|
Survival and death of endoplasmic-reticulum-stressed cells: Role of autophagy.
|
World J Biol Chem
|
2011
|
0.92
|
33
|
Induction of cell cycle arrest at G1 and S phases and cAMP-dependent differentiation in C6 glioma by low concentration of cycloheximide.
|
BMC Cancer
|
2010
|
0.92
|
34
|
Up-regulation of CD147 and matrix metalloproteinase-2, -9 induced by P-glycoprotein substrates in multidrug resistant breast cancer cells.
|
Cancer Sci
|
2007
|
0.91
|
35
|
Rational incorporation of selenium into temozolomide elicits superior antitumor activity associated with both apoptotic and autophagic cell death.
|
PLoS One
|
2012
|
0.91
|
36
|
Clinical management of recurrent breast cancer: development of multidrug resistance (MDR) and strategies to circumvent it.
|
Semin Oncol
|
2005
|
0.91
|
37
|
Targeting autophagic pathways for cancer drug discovery.
|
Chin J Cancer
|
2012
|
0.91
|
38
|
Inhibition of eEF-2 kinase sensitizes human glioma cells to TRAIL and down-regulates Bcl-xL expression.
|
Biochem Biophys Res Commun
|
2011
|
0.90
|
39
|
Integrated regulation of autophagy and apoptosis by EEF2K controls cellular fate and modulates the efficacy of curcumin and velcade against tumor cells.
|
Autophagy
|
2012
|
0.90
|
40
|
Dysfunction of nucleus accumbens-1 activates cellular senescence and inhibits tumor cell proliferation and oncogenesis.
|
Cancer Res
|
2012
|
0.88
|
41
|
Acidic pH induces topoisomerase II-mediated DNA damage.
|
Proc Natl Acad Sci U S A
|
2003
|
0.87
|
42
|
Interaction between CD147 and P-glycoprotein and their regulation by ubiquitination in breast cancer cells.
|
Chemotherapy
|
2008
|
0.86
|
43
|
A Phase I/pilot study of sequential doxorubicin/vinorelbine: effects on p53 and microtubule-associated protein 4.
|
Clin Cancer Res
|
2002
|
0.84
|
44
|
Inhibition of elongation factor-2 kinase augments the antitumor activity of Temozolomide against glioma.
|
PLoS One
|
2013
|
0.84
|
45
|
Involvement of Caveolin-1 in repair of DNA damage through both homologous recombination and non-homologous end joining.
|
PLoS One
|
2010
|
0.83
|
46
|
Diaza- and triazachrysenes: potent topoisomerase-targeting agents with exceptional antitumor activity against the human tumor xenograft, MDA-MB-435.
|
Bioorg Med Chem Lett
|
2002
|
0.82
|
47
|
A role for p53 in the regulation of extracellular matrix metalloproteinase inducer in human cancer cells.
|
Cancer Biol Ther
|
2009
|
0.82
|
48
|
The individualization of cancer therapy: the unexpected role of p53.
|
Trans Am Clin Climatol Assoc
|
2006
|
0.81
|
49
|
Identification of Sirtuin 3, a mitochondrial protein deacetylase, as a new contributor to tamoxifen resistance in breast cancer cells.
|
Biochem Pharmacol
|
2013
|
0.81
|
50
|
P-glycoprotein mediates resistance to histidine kinase inhibitors.
|
Mol Pharmacol
|
2004
|
0.81
|
51
|
eEF-2 kinase, another meddler in the "yin and yang" of Akt-mediated cell fate?
|
Autophagy
|
2011
|
0.80
|
52
|
Effect of the multidrug resistance protein on the transport of the antiandrogen flutamide.
|
Cancer Res
|
2003
|
0.80
|
53
|
11H-Isoquino[4,3-c]cinnolin-12-ones; novel anticancer agents with potent topoisomerase I-targeting activity and cytotoxicity.
|
Bioorg Med Chem
|
2004
|
0.79
|
54
|
NAC1 and HMGB1 enter a partnership for manipulating autophagy.
|
Autophagy
|
2011
|
0.78
|
55
|
Detection of anti-elongation factor 2 kinase (calmodulin-dependent protein kinase III) antibodies in patients with systemic lupus erythematosus.
|
Biochem Biophys Res Commun
|
2002
|
0.78
|
56
|
Lipopolysaccharide (LPS) potentiates hydrogen peroxide toxicity in T98G astrocytoma cells by suppression of anti-oxidative and growth factor gene expression.
|
BMC Genomics
|
2008
|
0.78
|
57
|
Roles of eEF-2 kinase in cancer.
|
Chin Med J (Engl)
|
2012
|
0.77
|
58
|
Triticuside A, a dietary flavonoid, inhibits proliferation of human breast cancer cells via inducing apoptosis.
|
Nutr Cancer
|
2013
|
0.76
|
59
|
Autophagy and apoptosis: rivals or mates?
|
Chin J Cancer
|
2013
|
0.75
|
60
|
Potentiation of the growth inhibition activity of 2-({4-[4-(acridin-9-ylamino)phenylthio]phenyl}(2-hydroxyethyl)amino)ethan-1-ol (CK0402) by Herceptin in SKBR-3 human breast cancer cells.
|
Exp Ther Med
|
2010
|
0.75
|
61
|
Phosphorylation of elongation factor-2 kinase differentially regulates the enzyme's stability under stress conditions.
|
Biochem Biophys Res Commun
|
2012
|
0.75
|
62
|
[Quantitative estimation of evapotranspiration from Tahe forest ecosystem, Northeast China].
|
Ying Yong Sheng Tai Xue Bao
|
2014
|
0.75
|
63
|
[Comparison of three daily global solar radiation models].
|
Ying Yong Sheng Tai Xue Bao
|
2014
|
0.75
|