Published in Cancer Res on March 15, 2006
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The combination of tephrosin with 2-deoxy-D-glucose enhances the cytotoxicity via accelerating ATP depletion and blunting autophagy in human cancer cells. Cancer Biol Ther (2011) 0.78
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Inhibition of eEF-2 kinase sensitizes human nasopharyngeal carcinoma cells to lapatinib-induced apoptosis through the Src and Erk pathways. BMC Cancer (2016) 0.75
Phosphorylation of elongation factor-2 kinase differentially regulates the enzyme's stability under stress conditions. Biochem Biophys Res Commun (2012) 0.75
IRS1 deficiency protects β-cells against ER stress-induced apoptosis by modulating sXBP-1 stability and protein translation. Sci Rep (2016) 0.75
Targeting translation initiation in breast cancer. Translation (Austin) (2014) 0.75
Functional analysis of a novel glioma antigen, EFTUD1. Neuro Oncol (2014) 0.75
Decreased ATF4 expression as a mechanism of acquired resistance to long-term amino acid limitation in cancer cells. Oncotarget (2017) 0.75
Tunicamycin induced endoplasmic reticulum stress promotes apoptosis of prostate cancer cells by activating mTORC1. Oncotarget (2017) 0.75
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Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell (2006) 11.79
Autophagy suppresses tumor progression by limiting chromosomal instability. Genes Dev (2007) 7.41
The coordinate regulation of the p53 and mTOR pathways in cells. Proc Natl Acad Sci U S A (2005) 7.38
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. Genes Dev (2007) 6.35
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Autophagy is induced in CD4+ T cells and important for the growth factor-withdrawal cell death. J Immunol (2006) 2.68
Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways. Genes Dev (2006) 2.66
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Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells. Cancer Res (2003) 1.71
Accurate prediction of protein torsion angles using chemical shifts and sequence homology. Magn Reson Chem (2006) 1.66
The CD44 receptor interacts with P-glycoprotein to promote cell migration and invasion in cancer. Cancer Res (2005) 1.57
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Effect of stathmin on the sensitivity to antimicrotubule drugs in human breast cancer. Cancer Res (2002) 1.56
Advanced glycation end-products induce tubular CTGF via TGF-beta-independent Smad3 signaling. J Am Soc Nephrol (2009) 1.45
Transcription-dependent degradation of topoisomerase I-DNA covalent complexes. Mol Cell Biol (2003) 1.43
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Extracellular matrix metalloproteinase inducer (CD147) confers resistance of breast cancer cells to Anoikis through inhibition of Bim. J Biol Chem (2006) 1.41
Overexpression of extracellular matrix metalloproteinase inducer in multidrug resistant cancer cells. Mol Cancer Res (2003) 1.39
A new HDL mimetic peptide that stimulates cellular cholesterol efflux with high efficiency greatly reduces atherosclerosis in mice. J Lipid Res (2010) 1.36
MK-2206, a novel allosteric inhibitor of Akt, synergizes with gefitinib against malignant glioma via modulating both autophagy and apoptosis. Mol Cancer Ther (2011) 1.33
Identification and characterization of an inhibitor of eukaryotic elongation factor 2 kinase against human cancer cell lines. Cancer Res (2003) 1.33
Reversal of stathmin-mediated resistance to paclitaxel and vinblastine in human breast carcinoma cells. Mol Pharmacol (2007) 1.29
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miR-30 inhibits TGF-β1-induced epithelial-to-mesenchymal transition in hepatocyte by targeting Snail1. Biochem Biophys Res Commun (2011) 1.25
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Regulation of the stability of P-glycoprotein by ubiquitination. Mol Pharmacol (2004) 1.19
Involvement of CtBP1 in the transcriptional activation of the MDR1 gene in human multidrug resistant cancer cells. Biochem Pharmacol (2007) 1.14
Quorum-sensing agr mediates bacterial oxidation response via an intramolecular disulfide redox switch in the response regulator AgrA. Proc Natl Acad Sci U S A (2012) 1.11
EMMPRIN expression as a prognostic factor in radiotherapy of cervical cancer. Clin Cancer Res (2008) 1.11
Effect of a single nucleotide polymorphism in the murine double minute 2 promoter (SNP309) on the sensitivity to topoisomerase II-targeting drugs. Cancer Res (2007) 1.10
Identification and characterization of small non-coding RNAs from Chinese fir by high throughput sequencing. BMC Plant Biol (2012) 1.09
Crp-dependent cytochrome bd oxidase confers nitrite resistance to Shewanella oneidensis. Environ Microbiol (2013) 1.09
MicroRNA-101 suppresses liver fibrosis by targeting the TGFβ signalling pathway. J Pathol (2014) 1.08
p300-Dependent ATF5 acetylation is essential for Egr-1 gene activation and cell proliferation and survival. Mol Cell Biol (2011) 1.08
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Involvement of CD147 in regulation of multidrug resistance to P-gp substrate drugs and in vitro invasion in breast cancer cells. Cancer Sci (2007) 1.05
Interaction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAIL-induced apoptosis. FEBS Lett (2010) 1.05
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Identification of the ubiquitin-proteasome pathway in the regulation of the stability of eukaryotic elongation factor-2 kinase. Cancer Res (2005) 1.01
Supplementation of the diet with high-viscosity beta-glucan results in enrichment for lactobacilli in the rat cecum. Appl Environ Microbiol (2006) 1.01
Cellular autophagy machinery is not required for vaccinia virus replication and maturation. Autophagy (2006) 1.01
Use of the ODD-luciferase transgene for the non-invasive imaging of spontaneous tumors in mice. PLoS One (2011) 1.00
Altered energy metabolism in cancer: a unique opportunity for therapeutic intervention. Cancer Biol Ther (2012) 1.00
Autophagy and adipogenesis: implications in obesity and type II diabetes. Autophagy (2010) 1.00
A matter of life or death (or both): understanding autophagy in cancer. Clin Cancer Res (2006) 0.99
Differential gene expression in tamoxifen-resistant breast cancer cells revealed by a new analytical model of RNA-Seq data. PLoS One (2012) 0.99
p70 S6 kinase and tau in Alzheimer's disease. J Alzheimers Dis (2008) 0.99
Oxidative stress-induced inhibition of adrenal steroidogenesis requires participation of p38 mitogen-activated protein kinase signaling pathway. J Endocrinol (2008) 0.98
ParaAT: a parallel tool for constructing multiple protein-coding DNA alignments. Biochem Biophys Res Commun (2012) 0.96
Direct differentiation of homogeneous human adipose stem cells into functional hepatocytes by mimicking liver embryogenesis. J Cell Physiol (2014) 0.96
Nanoporous polymer monoliths as adsorptive supports for robust photocatalyst of Degussa P25. J Colloid Interface Sci (2009) 0.96
Detection of mutations in the mitogen-activated protein kinase pathway in human melanoma. Clin Cancer Res (2003) 0.95
Over-expression of ubiquitin carboxy terminal hydrolase-L1 induces apoptosis in breast cancer cells. Int J Oncol (2008) 0.95
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Mammalian target of rapamycin (mTor) mediates tau protein dyshomeostasis: implication for Alzheimer disease. J Biol Chem (2013) 0.94
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Inhibition of glycogen synthase kinase 3β ameliorates D-GalN/LPS-induced liver injury by reducing endoplasmic reticulum stress-triggered apoptosis. PLoS One (2012) 0.93
Survival and death of endoplasmic-reticulum-stressed cells: Role of autophagy. World J Biol Chem (2011) 0.92
Induction of cell cycle arrest at G1 and S phases and cAMP-dependent differentiation in C6 glioma by low concentration of cycloheximide. BMC Cancer (2010) 0.92
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Up-regulation of CD147 and matrix metalloproteinase-2, -9 induced by P-glycoprotein substrates in multidrug resistant breast cancer cells. Cancer Sci (2007) 0.91