Published in Channels (Austin) on September 01, 2010
Store-operated calcium channels: new perspectives on mechanism and function. Cold Spring Harb Perspect Biol (2011) 1.72
Hypertonic saline inhibits arachidonic acid priming of the human neutrophil oxidase. J Surg Res (2011) 1.44
Orai3--the 'exceptional' Orai? J Physiol (2011) 1.07
STIM/Orai signalling complexes in vascular smooth muscle. J Physiol (2012) 1.05
Complex role of STIM1 in the activation of store-independent Orai1/3 channels. J Gen Physiol (2014) 0.99
The STIM1/Orai signaling machinery. Channels (Austin) (2013) 0.97
Mechanisms of STIM1 activation of store-independent leukotriene C4-regulated Ca2+ channels. Mol Cell Biol (2013) 0.93
STIM and ORAI proteins in the nervous system. Channels (Austin) (2015) 0.85
Emerging roles of Orai3 in pathophysiology. Channels (Austin) (2013) 0.84
STIM and Orai proteins and the non-capacitative ARC channels. Front Biosci (Landmark Ed) (2012) 0.84
Exploring the unique features of the ARC channel, a store-independent Orai channel. Channels (Austin) (2013) 0.79
Activation of ERK1/2 by store-operated calcium entry in rat parotid acinar cells. PLoS One (2013) 0.78
Orai channel-mediated Ca2+ signals in vascular and airway smooth muscle. Am J Physiol Cell Physiol (2015) 0.78
STIM and Orai isoform expression in pregnant human myometrium: a potential role in calcium signaling during pregnancy. Front Physiol (2014) 0.76
Orai3 Surface Accumulation and Calcium Entry Evoked by Vascular Endothelial Growth Factor. Arterioscler Thromb Vasc Biol (2015) 0.75
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature (2006) 14.78
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx. Curr Biol (2005) 14.53
STIM1, an essential and conserved component of store-operated Ca2+ channel function. J Cell Biol (2005) 13.11
Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai. Nature (2006) 7.22
STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1. Cell (2009) 6.92
Calcium release-activated calcium current in rat mast cells. J Physiol (1993) 6.33
Amplification of CRAC current by STIM1 and CRACM1 (Orai1). Nat Cell Biol (2006) 6.31
Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores. Proc Natl Acad Sci U S A (1993) 6.27
CRACM1 multimers form the ion-selective pore of the CRAC channel. Curr Biol (2006) 6.02
Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation. J Biol Chem (2008) 4.20
Biochemical and functional characterization of Orai proteins. J Biol Chem (2007) 3.87
The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers. Nature (2008) 3.46
CRACM1, CRACM2, and CRACM3 are store-operated Ca2+ channels with distinct functional properties. Curr Biol (2007) 3.12
Functional stoichiometry of the unitary calcium-release-activated calcium channel. Proc Natl Acad Sci U S A (2008) 3.07
Mapping the interacting domains of STIM1 and Orai1 in Ca2+ release-activated Ca2+ channel activation. J Biol Chem (2007) 3.05
Store-dependent and -independent modes regulating Ca2+ release-activated Ca2+ channel activity of human Orai1 and Orai3. J Biol Chem (2008) 2.75
Orai1 subunit stoichiometry of the mammalian CRAC channel pore. J Physiol (2007) 2.69
Calcium inhibition and calcium potentiation of Orai1, Orai2, and Orai3 calcium release-activated calcium channels. J Biol Chem (2007) 2.58
Presenilin-mediated modulation of capacitative calcium entry. Neuron (2000) 2.25
STIM1 regulates Ca2+ entry via arachidonate-regulated Ca2+-selective (ARC) channels without store depletion or translocation to the plasma membrane. J Physiol (2006) 2.17
I(ARC), a novel arachidonate-regulated, noncapacitative Ca(2+) entry channel. J Biol Chem (2000) 1.66
2-aminoethoxydiphenyl borate alters selectivity of Orai3 channels by increasing their pore size. J Biol Chem (2008) 1.66
Molecular determinants of the coupling between STIM1 and Orai channels: differential activation of Orai1-3 channels by a STIM1 coiled-coil mutant. J Biol Chem (2009) 1.65
Both Orai1 and Orai3 are essential components of the arachidonate-regulated Ca2+-selective (ARC) channels. J Physiol (2007) 1.54
Essential role of the N-terminus of murine Orai1 in store-operated Ca2+ entry. Biochem Biophys Res Commun (2007) 1.40
Ca2+ selectivity and fatty acid specificity of the noncapacitative, arachidonate-regulated Ca2+ (ARC) channels. J Biol Chem (2003) 1.35
The molecular architecture of the arachidonate-regulated Ca2+-selective ARC channel is a pentameric assembly of Orai1 and Orai3 subunits. J Physiol (2009) 1.34
Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domain. J Biol Chem (2009) 1.21
Agonist activation of arachidonate-regulated Ca2+-selective (ARC) channels in murine parotid and pancreatic acinar cells. J Physiol (2005) 1.19
The Orai1 severe combined immune deficiency mutation and calcium release-activated Ca2+ channel function in the heterozygous condition. J Biol Chem (2008) 1.03
Formyl-peptide receptor like 1: a potent mediator of the Ca2+ release-activated Ca2+ current ICRAC. Arch Biochem Biophys (2008) 0.91
Arachidonic acid stimulates extracellular Ca(2+) entry in rat pancreatic beta cells via activation of the noncapacitative arachidonate-regulated Ca(2+) (ARC) channels. Cell Calcium (2009) 0.80
Orai1 subunit stoichiometry of the mammalian CRAC channel pore. J Physiol (2007) 2.69
STIM1 regulates Ca2+ entry via arachidonate-regulated Ca2+-selective (ARC) channels without store depletion or translocation to the plasma membrane. J Physiol (2006) 2.17
Both Orai1 and Orai3 are essential components of the arachidonate-regulated Ca2+-selective (ARC) channels. J Physiol (2007) 1.54
Phosphorylation of inositol 1,4,5-trisphosphate receptors in parotid acinar cells. A mechanism for the synergistic effects of cAMP on Ca2+ signaling. J Biol Chem (2001) 1.51
Ca2+ selectivity and fatty acid specificity of the noncapacitative, arachidonate-regulated Ca2+ (ARC) channels. J Biol Chem (2003) 1.35
The molecular architecture of the arachidonate-regulated Ca2+-selective ARC channel is a pentameric assembly of Orai1 and Orai3 subunits. J Physiol (2009) 1.34
ARC channels: a novel pathway for receptor-activated calcium entry. Physiology (Bethesda) (2004) 1.28
Agonist activation of arachidonate-regulated Ca2+-selective (ARC) channels in murine parotid and pancreatic acinar cells. J Physiol (2005) 1.19
Cytosolic Ca(2+) and Ca(2+)-activated Cl(-) current dynamics: insights from two functionally distinct mouse exocrine cells. J Physiol (2002) 1.11
Calcineurin directs the reciprocal regulation of calcium entry pathways in nonexcitable cells. J Biol Chem (2003) 1.06
The Orai1 severe combined immune deficiency mutation and calcium release-activated Ca2+ channel function in the heterozygous condition. J Biol Chem (2008) 1.03
A mathematical model of fluid secretion from a parotid acinar cell. J Theor Biol (2007) 1.01
STIM1 and the noncapacitative ARC channels. Cell Calcium (2007) 1.00
A dynamic model of saliva secretion. J Theor Biol (2010) 0.99
Modulation of [Ca2+]i signaling dynamics and metabolism by perinuclear mitochondria in mouse parotid acinar cells. J Biol Chem (2003) 0.99
How many Orai's does it take to make a CRAC channel? Sci Rep (2013) 0.97
High glucose-induced apoptosis through store-operated calcium entry and calcineurin in human umbilical vein endothelial cells. Cell Calcium (2005) 0.94
Molecular basis of activation of the arachidonate-regulated Ca2+ (ARC) channel, a store-independent Orai channel, by plasma membrane STIM1. J Physiol (2013) 0.93
Orai channel-dependent activation of phospholipase C-δ: a novel mechanism for the effects of calcium entry on calcium oscillations. J Physiol (2011) 0.91
A plasma membrane-targeted cytosolic domain of STIM1 selectively activates ARC channels, an arachidonate-regulated store-independent Orai channel. Channels (Austin) (2012) 0.90
High-throughput analysis of promoter occupancy reveals new targets for Arx, a gene mutated in mental retardation and interneuronopathies. PLoS One (2011) 0.89
Ca2+-dependent protein kinase--a modulation of the plasma membrane Ca2+-ATPase in parotid acinar cells. J Biol Chem (2002) 0.88
Carboxyamidotriazole-induced inhibition of mitochondrial calcium import blocks capacitative calcium entry and cell proliferation in HEK-293 cells. J Cell Sci (2005) 0.88
Arachidonate-regulated Ca2+-selective (ARC) channel activity is modulated by phosphorylation and involves an A-kinase anchoring protein. J Physiol (2005) 0.86
Anchoring protein AKAP79-mediated PKA phosphorylation of STIM1 determines selective activation of the ARC channel, a store-independent Orai channel. J Physiol (2015) 0.84
Modelling the effects of calcium waves and oscillations on saliva secretion. J Theor Biol (2012) 0.80
Proteomic identification of calumenin as a G551D-CFTR associated protein. PLoS One (2012) 0.80
Orai channels - new insights, new ideas. J Physiol (2012) 0.78
Calcium signaling and cell fate: how can Ca (2+)signals contribute to wrong decisions for Chronic Lymphocytic Leukemic B lymphocyte outcome? Int J Dev Biol (2015) 0.77
Control of rectal gland secretion by blood acid-base status in the intact dogfish shark (Squalus acanthias). Respir Physiol Neurobiol (2006) 0.77
The ARC channel--an endogenous store-independent Orai channel. Curr Top Membr (2013) 0.76
Characterization of neurons from adult human skin-derived precursors in serum-free medium : a PCR array and immunocytological analysis. Exp Dermatol (2012) 0.75