Published in Am J Hum Genet on September 21, 2007
A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet (2009) 30.09
Origins and functional impact of copy number variation in the human genome. Nature (2009) 23.63
A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals. Am J Hum Genet (2009) 17.80
Genotype imputation for genome-wide association studies. Nat Rev Genet (2010) 14.59
Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. Nat Genet (2008) 12.07
Dindel: accurate indel calls from short-read data. Genome Res (2010) 8.62
Genotype and SNP calling from next-generation sequencing data. Nat Rev Genet (2011) 8.34
A linear complexity phasing method for thousands of genomes. Nat Methods (2011) 8.30
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet (2011) 7.80
Genotype-imputation accuracy across worldwide human populations. Am J Hum Genet (2009) 7.28
Practical issues in imputation-based association mapping. PLoS Genet (2008) 6.76
Simultaneous genotype calling and haplotype phasing improves genotype accuracy and reduces false-positive associations for genome-wide association studies. Am J Hum Genet (2009) 5.65
Improved whole-chromosome phasing for disease and population genetic studies. Nat Methods (2013) 5.43
Human dectin-1 deficiency and mucocutaneous fungal infections. N Engl J Med (2009) 5.27
Web-based, participant-driven studies yield novel genetic associations for common traits. PLoS Genet (2010) 5.02
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Nat Genet (2009) 4.97
Inference of population structure using dense haplotype data. PLoS Genet (2012) 4.87
The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research. Am J Hum Genet (2008) 4.79
Whole population, genome-wide mapping of hidden relatedness. Genome Res (2008) 4.72
Haplotype phasing: existing methods and new developments. Nat Rev Genet (2011) 4.66
Validating, augmenting and refining genome-wide association signals. Nat Rev Genet (2009) 4.56
Simple and efficient analysis of disease association with missing genotype data. Am J Hum Genet (2008) 4.52
A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose. PLoS Genet (2009) 4.32
A fast, powerful method for detecting identity by descent. Am J Hum Genet (2011) 4.26
Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia. J Infect Dis (2014) 4.24
GWAMA: software for genome-wide association meta-analysis. BMC Bioinformatics (2010) 4.11
Low concordance of multiple variant-calling pipelines: practical implications for exome and genome sequencing. Genome Med (2013) 3.90
Schizophrenia risk from complex variation of complement component 4. Nature (2016) 3.84
Missing data imputation and haplotype phase inference for genome-wide association studies. Hum Genet (2008) 3.65
Hunter-gatherer genomic diversity suggests a southern African origin for modern humans. Proc Natl Acad Sci U S A (2011) 3.53
Reconstructing Native American population history. Nature (2012) 3.49
High-resolution detection of identity by descent in unrelated individuals. Am J Hum Genet (2010) 3.41
Analyses and comparison of accuracy of different genotype imputation methods. PLoS One (2008) 3.41
Sparse whole-genome sequencing identifies two loci for major depressive disorder. Nature (2015) 3.25
A comprehensive evaluation of SNP genotype imputation. Hum Genet (2008) 3.18
Genome-wide association study identifies susceptibility loci for IgA nephropathy. Nat Genet (2011) 3.15
A comprehensive map of mobile element insertion polymorphisms in humans. PLoS Genet (2011) 3.14
Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry (2010) 3.13
Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study. Lancet Neurol (2012) 3.04
Quantifying prion disease penetrance using large population control cohorts. Sci Transl Med (2016) 3.04
Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned. Mol Psychiatry (2010) 2.95
Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups. Blood (2010) 2.93
Haplotypic analysis of Wellcome Trust Case Control Consortium data. Hum Genet (2008) 2.92
Detecting rare variants for complex traits using family and unrelated data. Genet Epidemiol (2010) 2.80
Avoiding the high Bonferroni penalty in genome-wide association studies. Genet Epidemiol (2010) 2.79
Global distribution of genomic diversity underscores rich complex history of continental human populations. Genome Res (2009) 2.76
Population genomics of Bronze Age Eurasia. Nature (2015) 2.58
Genomic ancestry of North Africans supports back-to-Africa migrations. PLoS Genet (2012) 2.51
Evolution of Darwin's finches and their beaks revealed by genome sequencing. Nature (2015) 2.50
Phasing of many thousands of genotyped samples. Am J Hum Genet (2012) 2.47
A general approach for haplotype phasing across the full spectrum of relatedness. PLoS Genet (2014) 2.38
SNP calling, genotype calling, and sample allele frequency estimation from New-Generation Sequencing data. PLoS One (2012) 2.37
A hidden markov model combining linkage and linkage disequilibrium information for haplotype reconstruction and quantitative trait locus fine mapping. Genetics (2009) 2.37
Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array. Genomics (2011) 2.31
Rapid and accurate multiple testing correction and power estimation for millions of correlated markers. PLoS Genet (2009) 2.30
Efficiency and power as a function of sequence coverage, SNP array density, and imputation. PLoS Comput Biol (2012) 2.29
Methodological challenges of genome-wide association analysis in Africa. Nat Rev Genet (2010) 2.27
Improving the accuracy and efficiency of identity-by-descent detection in population data. Genetics (2013) 2.26
A comparison of approaches to account for uncertainty in analysis of imputed genotypes. Genet Epidemiol (2011) 2.19
Accuracy of genome-wide imputation of untyped markers and impacts on statistical power for association studies. BMC Genet (2009) 2.16
Current status of genome-wide association studies in cancer. Hum Genet (2011) 2.14
Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder. Mol Psychiatry (2012) 2.09
Whole-genome haplotype reconstruction using proximity-ligation and shotgun sequencing. Nat Biotechnol (2013) 2.05
Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles. Gastroenterology (2011) 2.01
Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. Hum Mol Genet (2011) 1.98
A combined long-range phasing and long haplotype imputation method to impute phase for SNP genotypes. Genet Sel Evol (2011) 1.97
An application of Random Forests to a genome-wide association dataset: methodological considerations & new findings. BMC Genet (2010) 1.96
Length distributions of identity by descent reveal fine-scale demographic history. Am J Hum Genet (2012) 1.91
Structural genomic changes underlie alternative reproductive strategies in the ruff (Philomachus pugnax). Nat Genet (2015) 1.89
Case-control genome-wide association study of attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry (2010) 1.86
A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. Nat Genet (2013) 1.85
RFMix: a discriminative modeling approach for rapid and robust local-ancestry inference. Am J Hum Genet (2013) 1.82
A phasing and imputation method for pedigreed populations that results in a single-stage genomic evaluation. Genet Sel Evol (2012) 1.80
A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy. Nat Genet (2011) 1.77
Population genetic inference from personal genome data: impact of ancestry and admixture on human genomic variation. Am J Hum Genet (2012) 1.75
A common reference population from four European Holstein populations increases reliability of genomic predictions. Genet Sel Evol (2011) 1.74
Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens. Nat Genet (2014) 1.74
Performance of genotype imputation for rare variants identified in exons and flanking regions of genes. PLoS One (2011) 1.72
Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection. Am J Hum Genet (2010) 1.71
PRESTO: rapid calculation of order statistic distributions and multiple-testing adjusted P-values via permutation for one and two-stage genetic association studies. BMC Bioinformatics (2008) 1.71
Common and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project. Blood (2013) 1.69
Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC. Nat Genet (2010) 1.69
Genetic variants in pigmentation genes, pigmentary phenotypes, and risk of skin cancer in Caucasians. Int J Cancer (2009) 1.69
Imputation of low-frequency variants using the HapMap3 benefits from large, diverse reference sets. Eur J Hum Genet (2011) 1.68
Genomic diversity and evolution of the head crest in the rock pigeon. Science (2013) 1.68
Reconstructing the population genetic history of the Caribbean. PLoS Genet (2013) 1.68
HIBAG--HLA genotype imputation with attribute bagging. Pharmacogenomics J (2013) 1.66
HLA has strongest association with IgA nephropathy in genome-wide analysis. J Am Soc Nephrol (2010) 1.64
Structural diversity and African origin of the 17q21.31 inversion polymorphism. Nat Genet (2012) 1.62
ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: a comprehensive analysis from the Ovarian Cancer Association Consortium and The Cancer Genome Atlas. Gynecol Oncol (2013) 1.61
High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. PLoS Genet (2009) 1.61
The genetic ancestry of African Americans, Latinos, and European Americans across the United States. Am J Hum Genet (2014) 1.61
Genome-wide association mapping of root traits in a japonica rice panel. PLoS One (2013) 1.58
Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome. Genome Res (2013) 1.58
An integrative variant analysis pipeline for accurate genotype/haplotype inference in population NGS data. Genome Res (2013) 1.56
ImmunoChip study implicates antigen presentation to T cells in narcolepsy. PLoS Genet (2013) 1.55
Cryptic distant relatives are common in both isolated and cosmopolitan genetic samples. PLoS One (2012) 1.55
Shared and unique components of human population structure and genome-wide signals of positive selection in South Asia. Am J Hum Genet (2011) 1.52
Global analysis of the impact of environmental perturbation on cis-regulation of gene expression. PLoS Genet (2011) 1.51
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature (2007) 144.95
A haplotype map of the human genome. Nature (2005) 105.70
A new statistical method for haplotype reconstruction from population data. Am J Hum Genet (2001) 59.30
Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol Biol Evol (1995) 30.55
A high-resolution recombination map of the human genome. Nat Genet (2002) 28.66
A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase. Am J Hum Genet (2006) 28.32
A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet (2003) 26.59
Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet (2003) 21.52
Calibrating a coalescent simulation of human genome sequence variation. Genome Res (2005) 15.04
Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation. Am J Hum Genet (2005) 14.09
An E-M algorithm and testing strategy for multiple-locus haplotypes. Am J Hum Genet (1995) 13.84
HAPLO: a program using the EM algorithm to estimate the frequencies of multi-site haplotypes. J Hered (1995) 13.52
A comparison of phasing algorithms for trios and unrelated individuals. Am J Hum Genet (2006) 12.45
Evaluating coverage of genome-wide association studies. Nat Genet (2006) 11.40
A genotype calling algorithm for affymetrix SNP arrays. Bioinformatics (2005) 10.43
Partition-ligation-expectation-maximization algorithm for haplotype inference with single-nucleotide polymorphisms. Am J Hum Genet (2002) 10.12
Genotyping over 100,000 SNPs on a pair of oligonucleotide arrays. Nat Methods (2004) 9.52
Haplotype inference in random population samples. Am J Hum Genet (2002) 8.07
Haplotype reconstruction from genotype data using Imperfect Phylogeny. Bioinformatics (2004) 6.02
Multilocus association mapping using variable-length Markov chains. Am J Hum Genet (2006) 5.13
Gametic phase estimation over large genomic regions using an adaptive window approach. Hum Genomics (2003) 4.63
A method to address differential bias in genotyping in large-scale association studies. PLoS Genet (2007) 4.51
Efficient multilocus association testing for whole genome association studies using localized haplotype clustering. Genet Epidemiol (2007) 4.49
GERBIL: Genotype resolution and block identification using likelihood. Proc Natl Acad Sci U S A (2004) 4.36
A new algorithm for haplotype-based association analysis: the Stochastic-EM algorithm. Ann Hum Genet (2004) 3.24
The use of inferred haplotypes in downstream analyses. Am J Hum Genet (2007) 2.16
HaploRec: efficient and accurate large-scale reconstruction of haplotypes. BMC Bioinformatics (2006) 2.08
2SNP: scalable phasing based on 2-SNP haplotypes. Bioinformatics (2005) 1.76
A recurrent 16p12.1 microdeletion supports a two-hit model for severe developmental delay. Nat Genet (2010) 6.62
Haplotype phasing: existing methods and new developments. Nat Rev Genet (2011) 4.66
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol (2011) 3.52
High-resolution detection of identity by descent in unrelated individuals. Am J Hum Genet (2010) 3.41
Evaluation of Nyholt's procedure for multiple testing correction. Hum Hered (2005) 2.50
Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. PLoS Genet (2011) 2.33
Performance of genotype imputation for rare variants identified in exons and flanking regions of genes. PLoS One (2011) 1.72
Population structure can inflate SNP-based heritability estimates. Am J Hum Genet (2011) 1.54
Identity by descent between distant relatives: detection and applications. Annu Rev Genet (2012) 1.39
Interactions among genes in the ErbB-Neuregulin signalling network are associated with increased susceptibility to schizophrenia. Behav Brain Funct (2007) 1.19
Triallelic single nucleotide polymorphisms and genotyping error in genetic epidemiology studies: MDR1 (ABCB1) G2677/T/A as an example. Cancer Epidemiol Biomarkers Prev (2007) 1.15
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. Circ Cardiovasc Genet (2013) 1.12
Additive genetic variation in schizophrenia risk is shared by populations of African and European descent. Am J Hum Genet (2013) 1.07
Exome sequencing reveals novel rare variants in the ryanodine receptor and calcium channel genes in malignant hyperthermia families. Anesthesiology (2013) 1.06
Identity-by-descent-based heritability analysis in the Northern Finland Birth Cohort. Hum Genet (2012) 1.05
Interactions among genes influencing bacterial recognition increase IBD risk in a population-based New Zealand cohort. Hum Immunol (2009) 0.97
On reducing the statespace of hidden Markov models for the identity by descent process. Theor Popul Biol (2002) 0.93
Genes, diet and inflammatory bowel disease. Mutat Res (2007) 0.91
Genetic analysis of MDR1 and inflammatory bowel disease reveals protective effect of heterozygous variants for ulcerative colitis. Inflamm Bowel Dis (2009) 0.82
Efficient clustering of identity-by-descent between multiple individuals. Bioinformatics (2013) 0.79
Nucleotide-binding oligomerization domain containing 1 (NOD1) haplotypes and single nucleotide polymorphisms modify susceptibility to inflammatory bowel diseases in a New Zealand caucasian population: a case-control study. BMC Res Notes (2009) 0.79